HLA-DMA and DMB genotyping in patients with rheumatoid arthritis

Journal of Rheumatology

Volumn 24, Issue 3, 1997, Pages 442-444

  Yen, Jeng Hsien ^a   Chen, Chung Jen ^a   Tsai, Wen Chan ^a,b   Tsai, Jih Jin ^a   Chang, Jan Gowth ^a,c   Liu, Hong Wen ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c Jan ai Hospital   (Taiwan)

Author keywords

HLA DM; rheumatoid arthritis

Indexed keywords

HLA DMA ANTIGEN; HLA DMB ANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FEMALE; HLA TYPING; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ALLELES; ARTHRITIS, RHEUMATOID; BONE RESORPTION; GENE FREQUENCY; GENOTYPE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HLA-D ANTIGENS; HUMANS; PREVALENCE; RHEUMATOID FACTOR;

EID: 0030897431     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Kelly AP, Monaco JJ, Cho S, Trowsdale J: A new human HLA class II-related locus, DM. Nature 1991;353:571-3.
2. Nepom GT: MHC class-II molecules and autoimmunity. Annu Rev Immunol 1991;9:493-525.
3. Yen JH, Chen JR, Tsai WJ, Tsai JJ, Liu HW: HLA-DRB1 genotyping in patients with rheumatoid arthritis in Taiwan. J Rheumatol 1995;22:1450-4.
4. Gregersen PK, Silver J, Winchester RJ: The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis. Arthritis Rheum 1987;30:1205-13.
5. Yen JH, Chen JR, Tsai WJ, Tsai JJ, Liu HW: HLA-DPB1 polymorphism in patients with rheumatoid arthritis in Taiwan. J Rheumatol 1995;22:2034-7.
6. Morris P, Shaman J, Attaya M, et al: An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules. Nature 1994;368:551-4.
7. Fling SP, Arp B, Pilous D: HLA-DMA and -DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells. Nature 1994;368:554-8.
8. Eiken HG, Odland E, Boman H, Skjelelkvale L, Engebretsen LF, Apold J: Application of natural and amplification created restriction site for the diagnosis of PKU mutations. Nucleic Acids Res 1991;19:1427-30.
9. Cho S, Attaya M, Monaco JJ: New class II-like gene in the murine MHC. Nature 1991;353:573-6.
10. Carrington M, Yeager M, Mann D: Characterization of HLA-DMB polymorphism. Immunogenetics 1993;38:446-9.
11. Sanderson F, Powis SH, Kekky AP, Trowsdale J: Limited polymorphism in HLA-DM does not involve the peptide binding groove. Immunogenetics 1994;39:56-8.
12. Roche PA: HLA-DM: An in vivo facilitator of MHC class II peptide loading. Immunity 1995;3:259-62.
13. Benham A, Tulp A, Neefjes J: Synthesis and assembly of MHC-peptide complexes. Immunol Today 1995;16:359-62.
14. Denzin LK, Cresswell P: HLA-DM induces CLIP dissociation from MHC class II alpha beta dimers and facilitates peptide loading. Cell 1995;82:155-65.
15. Radley E, Alderton RP, Kelly A, Trowsdale J, Beck S: Genomic organization of HLA-DMA and HLA-DMB. J Biol Chem 1994;269:18834-8.