Release studies with rat brain cortical synaptosomes indicate that tramadol is a 5-hydroxytryptamine uptake blocker and not a 5-hydroxytryptamine releaser

European Journal of Pharmacology

Volumn 370, Issue 1, 1999, Pages 23-26

  Gobbi, Marco ^a   Mennini, Tiziana ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

( ) Tramadol; 5 HT (5 hydroxytryptamine, serotonin) carrier; 5 HT (5 hydroxytryptamine, serotonin) release; Synaptosome

Indexed keywords

2 ETHYL 1,2,3,4,6,7 HEXAHYDRO 2 HYDROXY 3 ISOBUTYL 9,10 DIMETHOXY 11BH BENZO[A]QUINOLIZINE; CITALOPRAM; FENFLURAMINE; TRAMADOL;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SEROTONIN UPTAKE; SYNAPSE VESICLE;

2H-BENZO(A)QUINOLIZIN-2-OL, 2-ETHYL-1,3,4,6,7,11B-HEXAHYDRO-3-ISOBUTYL-9,10-DIMETHOXY-; ANALGESICS, OPIOID; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; FENFLURAMINE; MALE; RATS; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; SYNAPTOSOMES; TRAMADOL;

EID: 0032898039     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00123-5     Document Type: Article

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