Retroviral insertions in Evi12, a novel common virus integration site upstream of Tra1/Grp94, frequently coincide with insertions in the gene encoding the peripheral cannabinoid receptor Cnr2

Journal of Virology

Volumn 73, Issue 5, 1999, Pages 3595-3602

  Valk, Peter J M ^a   Vankan, Yolanda ^a   Joosten, Marieke ^a   Jenkins, Nancy A ^b   Copeland, Neal G ^b   Löwenberg, Bob ^a   Delwel, Ruud ^a  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHROMOSOME 10; CHROMOSOME 12Q; FETUS; GENE INSERTION; GENE MAPPING; GENE REARRANGEMENT; IMMUNOBLOTTING; LEUKEMOGENESIS; MOLECULAR CLONING; MOUSE; MURINE LEUKEMIA; MURINE LEUKEMIA VIRUS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTO ONCOGENE; VIRUS CARCINOGENESIS; VIRUS DNA CELL DNA INTERACTION;

EID: 0032897969     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.5.3595-3602.1999     Document Type: Article

References (58)

1. Adams, J. M., and S. Cory. 1992. Oncogene co-operation in leukaemogenesis. Cancer Surv. 15:119-141.
2. Ben-David, Y., E. B. Giddens, K. Letwin, and A. Bernstein. 1991. Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1. Genes Dev. 5:908-918.
3. Berger, R., L. Theodor, J. Shoham, E. Gokkel, F. Brok-Simoni, K. B. Avraham, N. G. Copeland, N. A. Jenkins, G. Rechavi, and A. J. Simon. 1996. The characterization and localization of the mouse thymopoietin/lamina-associated polypeptide 2 gene and its alternatively spliced products. Genome Res. 6:361-370.
4. Bergeron, D., L. Poliquin, J. Houde, B. Barbeau, and E. Rassart. 1992. Analysis of proviruses integrated in Fli-1 and Evi-1 regions in Cas-Br-E MuLV-induced non-T-, non-B-cell leukemias. Virology 191:661-669.
5. Berns, A. 1991. Tumorigenesis in transgenic mice: identification and characterization of synergizing oncogenes. J. Cell Biochem. 47:130-135.
6. Brewer, J. W., J. L. Cleveland, and L. M. Hendershot. 1997. A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells. EMBO J. 16: 7207-7216.
7. Buchberg, A. M., H. G. Bedigian, N. A. Jenkins, and N. G. Copeland. 1990. Evi-2, a common integration site involved in murine myeloid leukemogenesis. Mol. Cell. Biol. 10:4658-4666.
8. Chang, S. C., A. E. Erwin, and A. S. Lee. 1989. Glucose-regulated protein (GRP94 and GRP78) genes share common regulatory domains and are coordinately regulated by common trans-acting factors. Mol. Cell. Biol. 9:2153-2162.
9. Chattopadhyay, S. K., B. M. Baroudy, K. L. Holmes, T. N. Fredrickson, M. R. Lander, H. C. D. Morse, and J. W. Hartley. 1989. Biologic and molecular genetic characteristics of a unique MCF virus that is highly leukemogenic in ecotropic virus-negative mice. Virology 168:90-100.
10. Copeland, N. G., and N. A. Jenkins. 1991. Development and applications of a molecular genetic linkage map of the mouse genome. Trends Genet. 7:113-118.
11. Cuypers, H. T., G. C. Selten, M. Zijlstra, R. E. de Goede, C. J. Melief, and A. J. Berns. 1986. Tumor progression in murine leukemia virus-induced T-cell lymphomas: monitoring clonal selections with viral and cellular probes. J. Virol. 60:230-241.
12. Dechert, U., M. Weber, M. Weber-Schaeuffelen, and E. Wollny. 1989. Isolation and partial characterization of an 80,000-dalton protein kinase from the microvessels of the porcine brain. J. Neurochem. 53:1268-1275.
13. Dechert, U., P. Weber, B. Konig, C. Ortwein, I. Nilson, W. Linxweiler, E. Wollny, and H. G. Gassen. 1994. A protein kinase isolated from porcine brain microvessels is similar to a class of heat-shock proteins. Eur. J. Biochem. 225:805-809.
14. Galiegue, S., S. Mary, J. Marchand, D. Dussossoy, D. Carriere, P. Carayon, M. Bouaboula, D. Shire, G. Le Fur, and P. Casellas. 1995. Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations. Eur. J. Biochem. 232:54-61.
15. Hartley, J. W., and W. P. Rowe. 1976. Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class. J. Virol. 19:19-25.
16. Holmes, K. L., W. Y. Langdon, T. N. Fredrickson, R. L. Coffman, P. M. Hoffman, J. W. Hartley, and H. C. D. Morse. 1986. Analysis of neoplasms induced by Cas-Br-M MuLV tumor extracts. J. Immunol. 137:679-688.
17. Holmes, K. L., E. Palaszynski, T. N. Fredrickson, H. C. D. Morse, and J. N. Ihle. 1985. Correlation of cell-surface phenotype with the establishment of interleukin 3-dependent cell lines from wild-mouse murine leukemia virus-induced neoplasms. Proc. Natl. Acad. Sci. USA 82:6687-6691.
18. Hunter, T. 1991. Cooperation between oncogenes. Cell 64:249-270.
19. Ihle, J. N., A. Rein, and R. Mural. 1984. Immunological and virological mechanisms in retrovirus-induced murine leukemogenesis. Viral Oncol. 4:95-137.
20. Jenkins, N. A., N. G. Copeland, B. A. Taylor, and B. K. Lee. 1982. Organization, distribution, and stability of endogenous ecotropic murine leukemia virus DNA sequences in chromosomes of Mus musculus. J. Virol. 43:26-36.
21. Jonkers, J., and A. Berns. 1996. Retroviral insertional mutagenesis as a strategy to identify cancer genes. Biochim. Biophys. Acta 1287:29-57.
22. Jonkers, J., H. C. Korswagen, D. Acton, M. Breuer, and A. Berns. 1997. Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. EMBO J. 16:441-450.
23. Juliusson, G., and M. Merup. 1998. Cytogenetics in chronic lymphocytic leukemia. Semin. Oncol. 25:19-26.
24. Koller, R., M. Krall, B. Mock, J. Bies, V. Nazarov, and L. Wolff. 1996. Mml1, a new common integration site in murine leukemia virus-induced promonocytic leukemias maps to mouse chromosome 10. Virology 224:224-234.
25. Langdon, W. Y., P. M. Hoffman, J. E. Silver, C. E. Buckler, J. W. Hartley, S. K. Ruscetti, and H. C. D. Morse. 1983. Identification of a spleen focus-forming virus in erythroleukemic mice infected with a wild-mouse ecotropic murine leukemia virus. J. Virol. 46:230-238.
26. Lee, A. Unpublished results.
27. Li, L. J., X. Li, A. Ferrario, N. Rucker, E. S. Liu, S. Wong, C. J. Gomer, and A. S. Lee. 1992. Establishment of a Chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94. J. Cell Physiol. 153:575-582.
28. Little, E., and A. S. Lee. 1995. Generation of a mammalian cell line deficient in glucose-regulated protein stress induction through targeted ribozyme driven by a stress-inducible promoter. J. Biol. Chem. 270:9526-9534.
29. Maki, R. G., R. L. Eddy, Jr., M. Byers, T. B. Shows, and P. K. Srivastava. 1993. Mapping of the genes for human endoplasmic reticular heat shock protein gp96/grp94. Somat. Cell Mol. Genet. 19:73-81.
30. Maki, R. G., L. J. Old, and P. K. Srivastava. 1990. Human homologue of murine tumor rejection antigen gp96: 5′-regulatory and coding regions and relationship to stress-induced proteins. Proc. Natl. Acad. Sci. USA 87:5658-5662.
31. Mazzarella, R. A., and M. Green. 1987. ERp99, an abundant, conserved glycoprotein of the endoplasmic reticulum, is homologous to the 90-kDa heat shock protein (hsp90) and the 94-kDa glucose regulated protein (GRP94). J. Biol. Chem. 262:8875-8883.
32. McCormick, T. S., K. S. McColl, and C. W. Distelhorst. 1997. Mouse lymphoma cells destined to undergo apoptosis in response to thapsigargin treatment fail to generate a calcium-mediated grp78/grp94 stress response. J. Biol. Chem. 272:6087-6092.
33. Menoret, A., K. Meflah, and J. Le Pendu. 1994. Expression of the 100-kDa glucose-regulated protein (GRP100/endoplasmin) is associated with tumorigenicity in a model of rat colon adenocarcinoma. Int. J. Cancer 56:400-405.
34. Miles, C., M. J. Sanchez, A. Sinclair, and E. Dzierzak. 1997. Expression of the Ly-6E.1 (Sca-1) transgene in adult hematopoietic stem cells and the developing mouse embryo. Development 124:537-547.
35. Morishita, K., E. Parganas, C. L. William, M. H. Whittaker, H. Drabkin, J. Oval, R. Taetle, M. B. Valentine, and J. N. Ihle. 1992. Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc. Natl. Acad. Sci. USA 89:3937-3941.
36. Morishita, K., D. S. Parker, M. L. Mucenski, N. A. Jenkins, N. G. Copeland, and J. N. Ihle. 1988. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines. Cell 54:831-840.
37. Moskow, J. J., F. Bullrich, K. Huebner, I. O. Daar, and A. M. Buchberg. 1995. Meis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 mice. Mol. Cell. Biol. 15:5434-5443.
38. Munro, S., K. L. Thomas, and M. Abu-Shaar. 1993. Molecular characterization of a peripheral receptor for cannabinoids. Nature 365:61-65.
39. Nakai, A., T. Kawatani, S. Ohi, H. Kawasaki, T. Yoshimori, Y. Tashiro, Y. Miyata, I. Yahara, M. Satoh, and K. Nagata. 1995. Expression and phosphorylation of BiP/GRP78, a molecular chaperone in the endoplasmic reticulum, during the differentiation of a mouse myeloblastic cell line. Cell Struct. Funct. 20:33-39.
40. Nakamura, T., D. A. Largaespada, M. P. Lee, L. A. Johnson, K. Ohyashiki, K. Toyama, S. J. Chen, C. L. Willman, I. M. Chen, A. P. Feinberg, N. A. Jenkins, N. G. Copeland, and J. D. Shaughnessy, Jr. 1996. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat. Genet. 12:154-158.
41. Nakamura, T., D. A. Largaespada, J. D. Shaughnessy, Jr., N. A. Jenkins, and N. G. Copeland. 1996. Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias. Nat. Genet. 12:149-153.
42. Nicchitta, C. V. 1998. Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96. Curr. Opin. Immunol. 10:103-109.
43. Nichols, J., and S. D. Nimer. 1992. Transcription factors, translocations, and leukemia. Blood 80:2953-2963.
44. Poirier, Y., C. Kozak, and P. Jolicoeur. 1988. Identification of a common helper provirus integration site in Abelson murine leukemia virus-induced lymphoma DNA. J. Virol. 62:3985-3992.
45. Quint, W., W. Boelens, P. van Wezenbeek, T. Cuypers, E. R. Maandag, G. Selten, and A. Berns. 1984. Generation of AKR mink cell focus-forming viruses: a conserved single-copy xenotrope-like provirus provides recombinant long terminal repeat sequences. J. Virol. 50:432-438.
46. Renault, B., J. Lieman, D. Ward, K. Krauter, and R. Kucherlapati. 1995. Localization of the human achaete-scute homolog gene (ASCL1) distal to phenylalanine hydroxylase (PAH) and proximal to tumor rejection antigen (TRA1) on chromosome 12q22-q23. Genomics 30:81-83.
47. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
48. Shannon, K. M., O. C. P., G. A. Martin, D. Paderanga, K. Olson, P. Dinndorf, and F. McCormick. 1994. Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders. N. Engl. J. Med. 330:597-601.
49. Srivastava, P. K., Y. T. Chen, and L. J. Old. 1987. 5′-Structural analysis of genes encoding polymorphic antigens of chemically induced tumors. Proc. Natl. Acad. Sci. USA 84:3807-3811.
50. Srivastava, P. K., C. A. Kozak, and L. J. Old. 1988. Chromosomal assignment of the gene encoding the mouse tumor rejection antigen gp96. Immunogenetics 28:205-207.
51. Valk, P., S. Verbakel, Y. Vankan, S. Hol, S. Mancham, R. Ploemacher, A. Mayen, B. Löwenberg, and R. Delwel. 1997. Anandamide, a natural ligand for the peripheral cannabinoid receptor is a novel synergistic growth factor for hematopoietic cells. Blood 90:1448-1457.
52. Valk, P. J., S. Hol, Y. Vankan, J. N. Ihle, D. Askew, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, N. J. de Both, B. Löwenberg, and R. Delwel. 1997. The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evill. J. Virol. 71:6796-6804.
53. Valk, P. J. M., M. Joosten, Y. Vankan, B. Löwenberg, and R. Delwel. 1997. A rapid RT-PCR based method to isolate complementary DNA fragments flanking retrovirus integration sites. Nucleic Acids Res. 25:4419-4421.
54. Vogelstein, B., and K. W. Kinzler. 1993. The multistep nature of cancer. Trends Genet. 9:138-141.
55. Wilkie, T. M., D. J. Gilbert, A. S. Olsen, X. N. Chen, T. T. Amatruda, J. R. Korenberg, B. J. Trask, P. de Jong, R. R. Reed, M. I. Simon, et al. 1992. Evolution of the mammalian G protein alpha subunit multigene family. Nat. Genet. 1:85-91.
56. Wolff, L. 1997. Contribution of oncogenes and tumor suppressor genes to myeloid leukemia. Biochim. Biophys. Acta 1332:67-104.
57. Yamagata, N., C. Shimazaki, T. Kikuta, H. Hirai, T. Sumikuma, Y. Sudo, E. Ashihara, H. Goto, T. Inaba, N. Fujita, and M. Nakagawa. 1997. A translocation between 3q21 and 12q24 in a patient with minimally differentiated acute myeloid leukemia (AML-M0). Cancer Genet. Cytogenet. 97:90-93.
58. Zani, V. J., N. Asou, D. Jadayel, J. M. Heward, J. Shipley, E. Nacheva, K. Takasuki, D. Catovsky, and M. J. Dyer. 1996. Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon. Blood 87:3124-3134.