Expression of the Ly-6E.1 (Sca-1) transgene in adult hematopoietic stem cells and the developing mouse embryo

Development

Volumn 124, Issue 2, 1997, Pages 537-547

  Milest, Colin ^a,c   Sanchez, Maria Jose ^a,d   Sinclair, Angus ^a,d   Dzierzak, Elaine ^a,b  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Hematopoietic cell; Ly 6E.1; Mouse; Sca 1; Stem cell; Transgene

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CONTROLLED STUDY; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; FLOW CYTOMETRY; GENE EXPRESSION; HEMATOPOIETIC STEM CELL; MARKER GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; START CODON; TRANSGENE;

ANIMALS; ANTIGENS, LY; BETA-GALACTOSIDASE; BONE MARROW TRANSPLANTATION; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, REPORTER; HEMATOPOIETIC STEM CELLS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; RADIATION CHIMERA; REGULATORY SEQUENCES, NUCLEIC ACID; TRANSCRIPTION, GENETIC; TRANSPLANTATION CHIMERA;

ANIMALIA;

EID: 0031046437     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Abramson, S., Miller, R. G. and Phillips, R. A. (1977). The identification in adult marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems. J. Exp. Med. 145, 1567-1579.
2. Aihara, Y., Bühring, H. J., Aihara, M. and Klein, J. (1986). An attempt to produce 'pre-T' cell hybridomas and to identify their antigens. Eur. J. Immunology 16, 1391-1399.
3. V mice. Proc. Natl. Acad. Sci. USA 86,4564-4568.
4. b haplotypes. Immunogenetics 29, 98-107.
5. Cray, C., Keane, R. W., Malek, T. R. and Levy, R. B. (1990). Regulation and selective-expresson of Ly-6A/E, a lymphocyte activation molecule, in the central nervous system. Mol. Brain Res. 8, 9-15.
6. Dillon, N. and Grosveld, F. (1993). Transcriptional regulation of multigene loci: Multilevel control. Trends Genet. 9, 134-137.
7. Dumont, F. J. and Boltz, R. C. (1987). The augmentation of surface Ly-6A/E molecules in activated T cells is mediated by endogenous interferon-γ. J. Immunol. 139, 4088-4095.
8. Dzierzak, E., Daly, B., Fraser, P., Larsson, L. and Müller, A. (1993). Thy-1 tk transgenic mice with a conditional lymphocyte deficiency. Internat. Immunol. 5, 975-984.
9. Dzierzak, E., Müller, A., Sinclair, A., Miles, C., Gillett, N., Daly, B., Sanchez, M.-J. and Medvinsky, A. (1995). Hematopoietic stem cell development in the mouse embryo. In Proceedings of the Ninth Conference on Hemoglohin Switching (ed. G. Stamatoyannopoulos), pp. 109-121. Incercept.
10. Dzierzak, E. and Medvinsky, A. (1995). Mouse embryonic hematopoiesis. Trends Genet. 11, 359-366.
11. Fraser, P., Hurst, J., Collis, P. and Grosveld, F. (1990). DNaseI hypersensitive sites 1, 2, and 3 of the human β-globin dominant control region directs position-independent expression. Nucleic Acids Res. 18, 3503-3508.
12. Gokkel, E., Grossman, Z., Ramot, B., Yarden, Y., Rechavi, G. and Givol, D. (1992). Structural organization of the murine c-kit proto-oncogene. Oncogene 7, 1423-1429.
13. Grosveld, F. G., van Assendelft, G. B., Greaves, D. R. and Kollias, G. (1987). Position-independent, high level expression of the human β-globin gene in transgenic mice. Cell 51, 975-985.
14. Hendriks, P. J., Martens, A. C. M., Visser, J. W. M. and Hagenbeek, A. (1994). Differential suppressionof background mammalian lysosomal β-galactosidase increases the detection sensitivity of LacZ marked leukemic cells. Anal. Biochem. 222, 456-460.
15. Huang, H. and Auerbach, R. (1993). Identification and characterization of hematopoietic stem cells from the yolk sac of the early mouse embryo. Proc. Natl. Acad. Sci. USA 90, 10110-10114.
16. Ikuta, K., Kina, T., MacNeil, I., Uchida, N., Peault, B., Chien, Y. and Weissman, I. L, (1990). A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells. Cell 62, 863-874.
17. Ikuta, K. and Weissman, I. L. (1992). Evidence that hematopoietic stem cells-express mouse c-kit but do not depend on steel factor for their generation. Proc. Natl. Acad. Sci. USA 89, 1502-1506.
18. Jordan, C. T., McKearn, J. P. and Lemischka, I. R. (1990). Cellular and developmental properties of fetal hematopoietic stem cell. Cell 61, 953-963.
19. Kahn, K. D., Lindwall, G., Maher, S. E. and Bothwell, A. L. M. (1990). Characterization of promoter elements of an interferon-inducible Ly-6E/A differentiation antigen which is expressed on activated T cells and hematopoietic stem cells. Mol. Cell Biol. 10, 5150-5159.
20. Kamiura, S., Nolan, C. M. and Meruelo, D. (1992). Long-range physical map of the Ly-6 complex: Mapping the Ly-6 multigene family by field-inversion and two-dimensional gel electrophoresis. Genomics 12, 89.
21. Kaufman, M. H. (1992). In The Atlas of Mouse Development, pp. 465-468. Academic Press: London, UK.
22. Kimura, S., Tada, N., Liu-Lam, Y. and Hammerling, U. (1984). Studies of the mouse Ly-6 alloantigen system: II. Complexities of the Ly-6 region. Immunogenetics 20, 47-56.
23. Krasnow, M. A., Cumberledge, S., Manning, G., Herzenberg, L. A. and Nolan, G. R. (1991). Whole animal sorting of Drosophila embryos. Science 251, 81-85.
24. Krause, D. S., Ito, T., Fackler, M. J., Smith, O. M., Collector, M. I., Sharkis, S. J. and May, W. S. (1994). Characterization of murine CD34, a marker for hematopoietic progenitor and stem cells. Blood 84, 691-701.
25. Lawrence, P. A., Johnston, P., MacDonald, P. and Struhl, G. (1987). Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even skipped genes. Nature 328, 440-442.
26. LeClair, K. P., Palfree, R. G. E., Flood, P. M., Hammerling, U. and Bothwell, A. (1986). Isolation of a murine Ly-6 cDNA reveals a new multigene family. EMBO J. 5, 3227-3234.
27. May, G. and Enver, T. (1995). Targeting gene expression to haemopoietic stem cells: a chromatin-dependent upstream element mediates cell type-specific expression of the stem cell antigen CD34. EMBO J. 14, 564-574.
28. McGrew, J. T. and Rock, K, L. (1991). Isolation, expression and sequence of the TAP/Ly-6A. 2 chromosomal gene. J. Immunol. 146,3663-3638.
29. Medvinsky, A. L., Samoylina, N. L., Müller, A. M. and Dzierzak, E. A. (1993). An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature 364, 64-67.
30. Michlem, H. S., Ford, C. E., Evans, E. P. and Gray, J. (1966). Interrelationships of myeloid and lymphoid cell studies with chromosome-marked cells transplanted into lethally irradiated mice. Proc. R. Soc. Lond. 165, 78.
31. Moore, M. A. S. and Metcalf, D. (1970). Ontogeny of the haematopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing mouse embryo. Br. J. Haematol. 18, 279-296.
32. Müller, A. M., Medvinsky, A., Strouboulis, J., Grosveld, R. and Dzierzak, E. (1994). Development of hematopoietic stem cell activity in the mouse embryo. Immunity 1, 291-301.
33. Müller-Sieburg, C. E., Whitlock, C. A. and Weissman, I. L. (1986). Isolation of two early B lymphocyte progenitors from mouse marrow: A committed pre-pre-B cell and a donogenic Thy-llo hematopoietic stem cell. Cell 44, 653-662.
34. Nolan, G. P., Fiering, S., Nicolas, J. -F. and Herzenberg, L. A. (1988). Fluorescence-activated cell analysis and sorting of viable mammalian cell based on β-d-galactosidase activity after transduction of Escherichia coli lacZ. Proc. Natl. Acad. Sci. USA 85, 2603-2607.
35. Palfree, R. G. E. and Hammeling, U. (1986). Biochemical characterization of the murine activated lymphocyte alloantigen Ly-6E. 1 controlled by the Ly-6locus. J. Immunol. 136, 594-600.
36. Ploemacher, R. E. and Brons, R. H. C. (1989). Separation of CFU-S from primitive cells responsible for reconstitution of the bone marrow hemopoietic stem cell compartment following irradiation: Evidence for a pre-CFU-S cell. Exp. Hematol. 17, 263-266.
37. Porter, A. C. G., Chernajovski, Y., Dale, T. C., Gilbert, C. S., Stark, G. R. and Kerr, I. M. (1988). Interferon response element of the human gene 6-16. EMBO J. 7, 85-92.
38. Reid, L. E., Basnett, A. H., Gilbert, C. S., Porter, A. C. G., Gewert, D. R., Stark, G. R. and Kerr, I. M. (1989). A single DNA response element can confer inducibility by both α and β interferons. Proc. Natl. Acad. Sci. USA 86, 840-844.
39. Reiser, H., Coligan, J., Palmer, E., Benacerraf, B. and Rock, K. L. (1988). Cloning and expression of a cDNA tor the T-cell-activating protein TAP. Proc. Natl. Acad. Sci USA 85, 2255-2259.
40. Rock, K. L., Yeh, E. T. H., Haber, S. I., Reiser, H. and Benacerraf, B. (1986). TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes. J. Exp. Med. 163, 315-333.
41. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). In Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
42. Sinclair, A. M. and Dzierzak E. A. (1993). Cloning of the complete Ly-6E. 1 gene and identification of DNaseI hypersensitive sites corresponding to expression in hematopoietic cells. Blood 82, 3052-3062.
43. Sinclair, A., Daly, B. and Dzierzak, E. (1996). The Ly-6E. 1 (Sca-1), gene requires a 3′ chromatin dependent region for high level γ-interferon induced hematopoietic cell expression. Blood 87, 2750-2761.
44. Spangrude, G. J., Aihara, Y., Weissman, I. L. and Klein, J. (1988a). The stem cell antigens Sca-1 and Sca-2 subdivide thymic and peripheral T lymphocytes into unique subsets. J. Immunol. 141, 3697-3707.
45. Spangrude, G. J. and Brooks, D. M. (1993). Mouse strain variability in the expression of the hematopoietic stem cell antigen Ly-6A/E by bone marrow cells. Blood 82, 3327-3332.
46. Spangrude, G. J., Heimfeld, S. and Weissman, I. L. (1988b). Purification and characterization of mouse hematopoietic stem cells. Science 241, 58-62.
47. Spanopoulou, E., Giguere, V. and Grosveld, G. (1988). Transcriptional unit of the murine Thy-1 gene: Different distribution of transcriptional initiation sites in brain. Mol. Cell Biol 8, 3847-3856.
48. Su, B. and Bothwell, A. L. M. (1989). Biosynthesis of a phosphatidylinositol-glycan-linked membrane protein: Signals for posttranslational processing of the Ly-6E antigen. Mol. Cell Biol. 9, 3369-3376.
49. Turpen, J. B., Knudson, M. and Hoefen, P. B. (1981). The early ontogeny of hematopoietic cells studied by grafting cytogenetically labeled tissue anlagen: localization of a prospective stem cell compartment. Dev Biol. 85, 99-112.
50. van de Rijn, M., Heimfeld, S., Spangrude, G. J. and Weissman, I. L. (1989). Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family. Proc. Natl. Acad. Sci. USA 86, 4634-4938.
51. Visser, J. W. M., Bauman, J. G. J., Mulder, A. H., Eliason, J. F. and de Leeuw, A. M. (1984). Isolation of murine pluripotent hemopoietic stem cells. J. Exp. Med. 59, 1579-1590.