Modulation of in vitro biomarkers of the carcinogenic process by chemopreventive agents

Anticancer Research

Volumn 19, Issue 1 A, 1999, Pages 35-44

  Lee, Sang Kook ^a   Song, Lynda ^a   Mata Greenwood, Eugenia ^a   Kelloff, Gary J ^b   Steele, Vernon E ^b   Pezzuto, John M ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biomarker assays; Chemopreventive agents

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; ANTINEOPLASTIC AGENT; BENZO[A]PYRENE; BIOLOGICAL MARKER; CAFFEIC ACID; CELL DNA; GENISTEIN; ORNITHINE DECARBOXYLASE; PHENOL DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE);

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BRONCHUS MUCOSA; CARCINOGENESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL METABOLISM; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTICARCINOGENIC AGENTS; BENZO(A)PYRENE; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; DNA; GLUTATHIONE TRANSFERASE; HL-60 CELLS; HUMANS; MICE; NAD(P)H DEHYDROGENASE (QUINONE); ORNITHINE DECARBOXYLASE;

EID: 0032897448     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Morse MA, Stoner GD: Cancer chemoprevention. Principles and prospects. Carcinogenesis 14: 1737-1746, 1993.
2. Kelloff GJ, Boone CW, Malone WF, Steele VE: Recent results in preclinkal and clinical drug development of chemopreventive agents at the National Cancer Institute. In: Cancer Chemoprevention, eds. Wattenberg L, Lipkin M, Boone CW, Kelloff, GJ, CRC press, Boca Raton, FL, pp. 41-56, 1992.
3. Kelloff GJ, Boone CW, Crowell JA, Steele VE: New agents for cancer chemoprevention. J Cell Biochem 26: 1-28, 1996.
4. Sharma S, Stutzman JD, Kelloff GJ, Steele VE: Screening of potential chemopreventive agents using biochemical markers of carcinogenesis. Cancer Res 54: 5848-5855, 1994.
5. Huberman E, Selkirk JK, Heidelberg C: Metabolism of polycyclic aromatic hydrocarbons in cell culture. Cancer Res 31: 2161-2167, 1971.
6. Sims P, Grover PL: Epoxides in polycyclic aromatic hydrocarbon metabolism and carcinogenesis. Adv Cancer Res 20: 165-274, 1974.
7. Fox CH, Selkirk JK, Price FM, Croy RG, Sanford KK, Cottler-Fox M: Metabolism of benzo(a)pyrene by human epithelial cells in vitro. Cancer Res 35: 3551-3557, 1975.
8. Duncan ME, Brookes P: Metabolism and macromolecular binding of diben(a,c)anthracene and diben(a,c)anthracene by mouse embryo cells in culture. Int J Cancer 9: 349-352, 1972.
9. Ranadive DV, Talageri VR, Bhide SV: Urethane and 3,4-benzo(a) pyrene interactions with macromolecules of human cells grown in vitro. Indian J Biochem Biophys 12: 58-59, 1975.
10. Perara FP, Poirier MC, Yuspa SH, Nakayama J, Jaretzki A, Curnen MM, Knowles DM, Weinstein IB: A pilot project in molecular cancer epidemiology: Determination of benzo(a)pyrene-DNA adducts in animal and human tissues by immunoassay. Carcinogenesis 3: 1405-1410, 1982.
11. Teel RW, Merrill SB, Dixit R, Stoner GD: Ellagic acid toxicity and interaction with benzo(a)pyrene and benzo(a)pyrene-7,8-dihydrodiol in human bronchial epithelial cells. Cell Biol Toxicol 2: 53-56, 1986.
12. Talalay P: Mechanisms of induction of enzymes that protect against chemical carcinogenesis. Proc Natl Acad Sci USA 85: 8261-8265, 1988.
13. Prestera T, Zhang Y, Spencer SR, -Wilczak CA, Talalay P: The electrophile counterattack response: Protection against neoplasia and toxicity. Adv Enzyme Regul 33: 281-296, 1993.
14. Reddel RR, Ke Y, Gerwin BI, McMenamin MG, Lechner JF, Su RT, Brash DE, Park J, Rhim JS, Harris CC: Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strantium phosphate coprecipitation with a plasmid containing SV40 early region genes. Cancer Res 48: 1904-1909, 1988.
15. Fischer-Nielsen A, Jeding IB, Loft S: Radiation-induced formation of 8-hydroxy-2'-deoxyguanosine and its prevention by scavengers. Carcinogenesis 15: 1609-1612, 1994.
16. Cerutti PA, Trump BF: Inflammation and oxidative stress in carcinogenesis. Cancer Cells 3: 1-7, 1991.
17. Troll W, Wiesner R: The role of oxygen radicals as a possible mechanism of tumor promotion. Ann Rev Pharmacol Toxicol 25: 509-528, 1985.
18. McCann P, Pegg AE: Ornithine decarboxylase as an enzyme target for therapy. Pharmacol Ther 54: 195-215, 1992.
19. O'Brien TG: The induction of ornithine decarboxylase as an early, possibly obligatory event in mouse skin carcinogenesis. Cancer Res 36: 2644-2653, 1976.
20. Boutwell RK, Verma AK: Effects of vitamin A and related retinoids on the biochemical process of linked to carcinogenesis. Pure Appl Chem 51: 857-866, 1979.
21. Matsushima M, Takano S, Erturk E, Bryan G: Induction of ornithine decarboxylase activity in mouse urinary bladder by L-tryptophan and some of its metabolites. Cancer Res 42: 3587-3591, 1982.
22. Rozhin J, Wilson PS, Bull AW, Nigro ND: Ornithine decarboxylase activity in the rat and human colon. Cancer Res 44: 3226-3230, 1984.
23. Verma AK, Shapas BG, Rice HM, Boutwell RK: Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and skin tumor promotion. Cancer Res 39: 419-425, 1979.
24. Kelloff GJ, Boone CW, Crowell JA, Steele VE, Lubet RA, Sigman CS: Chemopreventive drug development: Perspective and progress. Cancer Epidem Biomarkers Prevent 3: 83-98, 1994.
25. Talalay P, De Long MJ, Prochaska HJ: Molecular mechanisms in protection against carcinogenesis. In: Cancer Biology and Therapeutics, eds. Cory JG, Szentivani A, Plenum Press, New York, pp. 197-216, 1987.
26. Prochaska HI, Talalay P: Role of NAD(P)H:quinone reductase in protection against the toxicities of quinones and related agents. In: Oxidative Stress. Oxidants and Antioxidants. ed. Sies H, Academic Press, London, pp. 195-211, 1991.
27. Prochaska HJ, Talalay P: Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver. Cancer Res 48: 4776-4782, 1988.
28. Benson AM, Batzinger RP, Ou SL, Bueding E, Cha Y, Talalay P: Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants. Cancer Res 38: 4486-4495, 1978.
29. Cha Y, Bueding E: Effects of 2(3)-tert-butyl-4-hydroxyanisole administration on the activities of several hepatic microsomal and cytoplasmic enzymes in mice. Biochem Pharmacol 28: 1917-1921, 1979.
30. Pearson WR, Windle JJ, Morrow JF, Benson AM, Talalay P: Increased synthesis of gluatathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of RNA. J Biol Chem 258: 2052-2062, 1983.
31. Davis RW, Thomas M, Cameron J, John TP, Scherer S, Padgett RA: Rapid DNA isolations for enzymatic and hybridization analysis. Meth Enzymol 65; 404-411, 1980.
32. Swanson SW, Pezzuto JM: Enhancement of benzo(a)pyrene metabolism mediated by retinol acetate in cultured human bronchial epithelial cells. Oncol Rep 2: 1011-1015, 1995.
33. Autrup H: Separation of water-soluble metabolites of benzo(a)pyrene formed by cultured human colon. Biochem Pharmacol 28: 1727-1730, 1974.
34. Gerhäuser C, Mar W, Lee SK, Suh N, Luo Y, Kosmeder J, Luyengi L, Fong HHS, Kinghorn AD, Moriarty RM, Mehta R. Constantinou A, Moon RC, Pezzuto JM: Rotenoids mediate potent cancer chemopreventive activity through transcriptional regulation of ornithine decarhoxylase. Nature Med 1: 260-266, 1995.
35. Suh N, Luyengi L, Fong HHS, Kinghorn AD, Pezzuto JM: Discovery of natural product chemopreventive agents utilizing HL-60 cell differentiation as a model. Anticancer Res 15: 233-240, 1995.
36. Gerhäuser C, You M, Liu J, Moriarty RM, Hawthorne M, Mehta RG, Moon RC, Pezzuto JM: Cancer chemopreventive potential of sulforamate, a novel analogue of sulforaphane that induces phase 2 drug-metabolizing enzymes. Cancer Res 57: 272-278, 1997.
37. Habig WH, Pabst MJ, Jakoby WB: Glutathione S-transferase. The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139, 1974.
38. Zhang Y, Talalay P, Cho CG, Posner GH: A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proc Natl Acad Sci USA 89: 2399-2403, 1992.
39. Sud'ina GF, Mirzoeva OK, Pushkareva MA, Korshunova GA, Sumbatyan NV, Varfolomeev SD: Caffeic acid phenethyl ester as a lipoxygenase inhibitor with antioxidant properties. FEBS Lett 329: 21-24, 1993.
40. 2 production. Cancer Detect Prevent 19: 292-298, 1995.
41. Huang MT, Ma W, Yen P, Xie JG, Man J, Frenkel K, Grunberger D, Conney AH: Inhibitory effects of caffeic acid phenethyl ester (CAPE) on 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mouse skin and the synthesis of DNA, RNA and protein in HeLa cells. Carcinogenesis 17: 761-765, 1996.
42. Ansher SS, Dolan P, Bueding E: Chemopreventive effects of two dithiolthiones and of butylhydroxyanisol against carbon tetrachloride and acetaminophen toxicity. Hepatol 3: 932-935, 1983.
43. Ansher SS, Dolan P, Bueding E: Biochemical effects of dithiolthiones. Food Chem Toxicol 24: 405-414, 1986.
44. Kensler TW, Groopman JD, Eaton DL, Curphey TJ, Roebuck BD: Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione. Carcinogenesis 13: 95-100, 1992.
45. Kensler TW, Styczynski P, Groopman JD, Helzlsouer K, Curphey R, Maxuitenko Y, Roebuck BD: Mechanism of chemoprotection of oltipraz. J Cell Biochem 161: 167-172, 1992.
46. Kessler FK, Ritter JK: Induction of a rat liver benzo(a)pyrene-trans7,8-dihydrodiol glucuronidating activity by oltipraz and β-naphthoflavone. Carcinogenesis 18: 107-114, 1997.
47. Akiyama T, Ishida J, Nakagawa S, Ogawara H, Watanabe S, Itoh N. Shibuya M, Fukami Y: Genistein, a specific inhibitor of tyrosine-specific protein kinases. J Biol Chem 262: 5592-5595, 1987.
48. Barnes S, Grubbs C, Setchell KDR, Carlson J: Soybeans inhibit mammary tumors in models of breast cancer. In: Mutagens and Carcinogens in the Diet. ed. Pariza M, Wiley-Liss. New York, pp. 239-253, 1990.
49. Messina MJ, Persky V, Setchell KDR, Barnes S: Soy intake and cancer risk: a review of in vitro and in vivo data. Nutr Cancer 21: 113-131, 1994.
50. Wei H, Wei L, Bowen R, Frenkel K, Barnes S: Inhibition of tumor promoter-induced hydrogen peroxide production in vitro and in vivo by genistein. Nutr Cancer 20: 1-12, 1993.
51. Wei H, Bowen R, Cai O, Barnes S, Wang Y: Antioxidant and antipromotional effects of the soybean isoflavone genistein. Proc Soc Exp Biol Med 208: 124-130, 1995.
52. Zhang Y, Talalay P, Cho CG, Posner GH: A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure. Proc Natl Acad Sci USA 89: 2399-2403, 1992.
53. Zhang Y, Kensler TW, Cho CG, Posner GH, Talalay P: Anti-carcinogenic activities of sulforaphane and structurally related synthetic norboryl isothiocyanates. Proc Natl Acad Sci USA 91: 3147-3150, 1994.
54. Barcelo S, Gardiner JM, Gescher A, Chipman JK: CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane. Carcinogenesis 17: 277-282, 1996.