Allelic loss of 11q13 as detected by MEN1-FISH is not associated with mutation of the MEN1 gene in lymphoid neoplasms

Leukemia

Volumn 13, Issue 1, 1999, Pages 85-91

  Thieblemont, C ^a   Pack, S ^a   Sakai, A ^a   Beaty, M ^a   Pak, E ^a   Vortmeyer, A O ^a   Wellmann, A ^a   Zhuang, Z ^a   Jaffe, E S ^a   Raffeld, M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Chromosomal deletions; MEN1; Non Hodgkin's lymphoma; Tumor suppressor gene

Indexed keywords

ARTICLE; B CELL LYMPHOMA; CHROMOSOME 11Q; CHRONIC LYMPHATIC LEUKEMIA; DELETION MUTANT; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLICULAR LYMPHOMA; GENE LOSS; GENE REARRANGEMENT; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MANTLE CELL LYMPHOMA; MULTIPLE ENDOCRINE NEOPLASIA; NONHODGKIN LYMPHOMA; NUCLEIC ACID BASE SUBSTITUTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM; T CELL LYMPHOMA; TUMOR SUPPRESSOR GENE;

EID: 0032897406     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401216     Document Type: Article

References (65)

1. Yunis JJ, Oken MM, Kaplan ME, Ensrud KM, Howe KR, Theologides A. Distinctive chromosomal abnormalities in histologic subtypes of non-Hodgkin's lymphoma. New Engl J Med 1982; 307: 1231-1236.
2. Bloomfield CD, Arthur DC, Frizzera C, Levine EG, Peterson BA, Gajl-Peczalska KJ. Nonrandom chromosome abnormalities in lymphoma. Cancer Res 1983; 43: 2975-2984.
3. Croce CM, Nowell PM. Molecular basis of human B cell neoplasia. Blood 1985; 65: 1-7.
4. Chaganti RSK, Doucette LA, Offit K, Filippa DA, Allen GJ, Condon MR, Jhanwar SC, Clarkson BD, Lieberman PH. Specific translocations in non-Hodgkin's lymphoma: incidence, molecular detection, and histological and clinical correlations. Cancer Cells 1989; 7: 33-36.
5. Yunis JJ, Frizzera G, Oken MM, McKenna J. Theologides A, Arnesen M. Multiple recurrent genomic defects in follicular lymphoma. A possible model for cancer. New Engl J Med 1987; 316: 79-84.
6. Gaidano G, Hauptschein RS, Parsa NZ, Offit K, Rao PH, Lenoir G, Knowles DM, Chaganti RS, Dalla-Favera R. Deletions involving two distinct regions of 6q in B-cell non-Hodgkin lymphoma. Blood 1992; 80: 1781-1787.
7. Maseki N, Hayashi Y, Kaneko Y, Sakurai M. Partial loss of the short arm of chromosome 9 in leukemia and lymphoma. Cancer Cenet Cytogenet 1986; 22: 89-91.
8. Pollak C, Hagemeijer A. Abnormalities of the short arm of chromosome 9 with partial loss of material in hematological disorders. Leukemia 1987; 7: 541-548.
9. Fernandez-Piqueras J, Santos J, Perex de Castro I, Melendez B, Martinez B, Robledo M, Rivas C, Benitez J. Frequent allelic losses of 9p21 markers and low incidence of mutations at p16(CDKN2) gene in non-Hodgkin lymphomas of B-cell lineage. Cancer Genet Cytogenet 1997; 98: 63-68.
10. Rodriguez MA, Ford RJ, Goodacre A, Selvanayagam P, Cabanillas F, Deisseroth AB. Chromosome 17- and p53 changes in lymphoma. Br J Haematol 1991; 79: 575-582.
11. Ponder B. Gene losses in human tumors. Nature 1988; 335: 400-402.
12. Stanbridge EJ. Human tumor suppressor genes. Annu Rev Genet 1990; 24: 615-657.
13. Marshall CJ. Tumor suppressor genes. Cell 1991; 64: 313-326.
14. Kamb A, Shattuck-Eidens D, Eeles R, Liu Q, Gruis NA, Ding W, Hussey C, Tran T, Miki Y, Weaver-Feldhaus J, McClure M, Aitken JF, Anderson DE, Bergman W, Frants R, Goldgar DE, Green A, MacLennan R, Martin NG, Meyer LJ, Youl P, Zone JJ, Skolnick MH, Cannon-Albright LA. Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat Genet 1994; 8: 23-26.
15. Isobe M, Emanuel BS, Givol D, Oren M, Croce CM. Localization of gene for human p53 tumour antigen to band 17p13. Nature 1986; 320: 84-85.
16. Kobayashi H, Espinosa R III, Fernald AA, Begy C, Diaz MO, Le Beau MM, Rowley JD. Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization. Genes Chromosom Cancer 1993; 8: 246-252.
17. Slavutsky I, Labal de Vinuesa M, Estévez ME, Sen L, Dupont J, Larripa I. Chromosome studies in human hematologic diseases: non-Hodgkin's lymphomas. Haematologica 1987; 72: 29-37.
18. Juliusson G, Gahrton G. Chromosome aberrations in B-cell chronic lymphocytic leukemia. Pathogenetic and clinical implications. Cancer Genet Cytogenet 1990; 45: 143-160.
19. Juliusson G, Oscier DG, Fitchett M, Ross FM, Stockdill G, Mackie MJ, Parker AC, Castoldi GL, Guneo A, Knuutila S, Elonen E, Gahrton G. Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. New Engl J Med 1990; 323: 720-724.
20. Hernandez JM, Mecucci C, Creil A, Meeus P, Michaux L, Van Hoof A, Verhoet G, Louwagie A, Scheiff J-M, Michaux J-L, Boogaerts M, Van den Berghe H. Cytogenetic analysis of B cell chronic lymphoid leukemias classified according to morphologic and immunophenotypic (FAB) criteria. Leukemia 1995; 9: 2140-2146.
21. Fegan C, Robinson H, Thompson P, Whiltaker JA, White D. Karyotypic evolution in CLL. Identification of a new sub-group of patients with deletions of 11q and advanced of progressive disease. Leukemia 1995; 9: 2003-2008.
22. Mark J, Ekedahl C, Dahlenfors R. Characteristics of the banding patterns in non-Hodgkin and non-Burkitt lymphomas. Hereditas 1978; 88: 229-242.
23. Palka C, Fioritone G, Lombardo M, Donti E, Calabrese G, Stuppia L, Di Marco G, Franchi PG, Parruti G, Geraci L. Chromosome abnormalities in PHA-stimulated and non stimulated bone marrow cultures from patients with non-Hodgkin lymphoma. Haematologica 1988; 73: 489-494.
24. Yunis JJ. Recurrent chromosomal defects are found in most patients with acute nonlymphocytic leukemia. Cancer Genet Cytogenet 1984; 11: 125-137.
25. Koduru PR, Filippa DA, Richardson ME, Jhanwar SC, Chaganti SR, Koziner B, Clarkson BD, Lieberman PH, Chaganti RS. Cytogenetic and histologic correlations in malignant lymphomas. Blood 1987; 69: 97-102.
26. Nishida K, Taniwaki M, Misawa S, Abe T. Nonrandom rearrangement of chromosome 14 at band q32.33 in human lymphoid malignancies with mature B-cell phenotype. Cancer Res 1989; 49: 1275-1281.
27. Takechi M, Tanaka K, Hashimoto T, Asaoku H, Dohy H, Kikuchi M, Kamada N. Cytogenetic, molecular biological and clinical study of B cell lymphomas with 14;18 translocation in Japanese patients. Leukemia 1991; 5: 1069-1075.
28. Kaneko Y, Frizzera G, Shikano T, Kobayashi H, Maseki N, Sakurai M. Chromosomal and immunophenotypic patterns in T cell acute lymphoblastic leukemia (T ALL) and lymphoblastic lymphoma (LBL). Leukemia 1989; 3: 886-892.
29. Larsson C, Skogseid B, Öberg K, Nakamura Y, Nordenskjöld M. Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma. Nature 1988; 332: 85-87.
30. Bale SJ, Bale AE, Stewart K, Dachowski L, McBride OW, Glaser T, Green SE III, Mulvihill JJ, Brandi ML, Sakaguchi K, Aurbach GD, Marx SJ. Linkage analysis of multiple endocrine neoplasia type 1 with INT2 and other markers on chromosome 11. Genomics 1989; 4: 320-322.
31. Bystrom CC, Larsson C, Blomberg K, Sandelin U, Falkmer B, Skogseid B, Öberg K, Wermer S, Nordenskjöld M. Localization of the MEN1 gene to a small region within the chromosome 11q13 by deletion mapping in tumors. Proc Natl Acad Sci USA 1990; 87: 1968-1972.
32. Thakker RV, Wooding C, Pang JT, Farren B, Harding B, Anderson DC, Besser GM, Bouloux P, Brenton DP, Buchanan KD, Edwards CR, Heath DA, Jackson CE, Jansen S, Lips K, Norum RA, Sampson J, Shalet SM, Taggart RT, Tailor D, Wheeler MH, Woollard PM, Yates J. Linkage analysis of 7 polymorphic markers at chromosome 11p11.2-11q13 in 27 multiple endocrine neoplasia type 1 families. Ann Hum Genet 1993; 57: 17-25.
33. Courseaux A, Grosgeorge J, Gaudray P, Pannett AA, Forbes SA, Williamson C, Bassett D, Thakker RV, Teh BT, Farnebo F, Shepherd J, Skogseid B, Larsson C, Giraud S, Zhang CX, Salandre J, Calender A. Definition of the minimal MEN1 candidate area based on a 5-Mb integrated map of proximal 11q13. Genomics 1996; 37: 354-365.
34. Smith CM, Wells SA, Gerhard DS. Mapping eight new polymorphism in 11q13 in the vicinity of the multiple endocrine neoplasia type 1: identification of a new distal recombinant. Hum Genet 1995; 96: 377-387.
35. Debelenko LV, Emmert-Buck MR, Manickam P, Kester M-B, Guru SC, Difranco EM, Olufemi S-E, Agarwal S, Lubensky IA, Zhuang Z, Burns AL, Speigel AM, Liotta LA, Collins FS, Marx SJ, Chandrasekharappa SC. Haplotype analysis defines a new minimal interval for multiple endocrine neoplasia type 1 (MEN1) gene. Cancer Res 1997; 57: 1039-1042.
36. Metz DC, Jensen RT, Bale A, Skarulis MC, Eastman R, Nieman L, Norton JA, Friedman E, Larsson C, Amorosi A, Brandi ML, Marx SJ. Multiple endocrine neoplasia type 1 : clinical features and management. In: Bileezekian JP, Levine MA, Marcus R (eds). The Parathyroids. Raven Press: New York; 1994, pp 591-646.
37. Chandrasekharappa SC, Guru SC, Manickam P, Olufemi S-E, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Crabtree JS, Wang Y, Roe BA, Weisemann J, Boguski MS, Agarwal SK, Kester MB, Kim YS, Heppner C, Dong Q, Spiegel AM, Burns AL, Marx SJ. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science 1997; 276: 404-407.
38. Larsson C, Weber G, Teh BT, Lagercrantz J. Genetics of multiple endocrine neoplasia type 1. Ann NY Acad Sci 1994; 733: 453-463.
39. Thakker RV, Bouloux P, Wooding C, Chotai K, Broad PM, Spurr NK, Besser GM, O'Riordan J. Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles of chromosome 11. New Engl J Med 1989; 321: 218-224.
40. Debelenko LV, Zhuang Z, Emmert-Buck MR, Chandrasekharappa SC, Manickam P, Guru SC, Marx SJ, Skarulis MC, Spiegel AM, Collins FS, Jensen RT, Liotta LA, Lubensky IA. Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type-1 associated and sporadic gastrinomas and pancreatic endocrine tumors. Cancer Res 1997; 57: 2238-2243.
41. Lubensky IA, Debelenko LV, Zhuang Z, Emmert-Buck MR, Dong Q, Chandrasekharappa SC, Guru SC, Manickam P, Olufemi S-E, Marx SJ, Spiegel AM, Collins FS, Liotta LA. Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients. Cancer Res 1996; 56; 5272-5278.
42. Beckers A, Abs R, Reyniers E, De Boulle K, Steavenaert A, Heller FR, Klöppel G, Meurisse M, Willems PJ. Variable regions of chromosome 11 loss in different pathological tissues of a patient with the multiple endocrine neoplasia type 1 syndrome. J Clin Endocrinol Metab 1994; 79: 1498-1502.
43. Radford DM, Ashley SW, Wells SA Jr, Gerhard DS. Loss of heterozygosity of markers on chromosome 11 in tumors from patients with multiple endocrine neoplasia syndrome type 1. Cancer Res 1990; 50: 6529-6533.
44. Bale AE, Norton JA, Wong EL, Fryburg JS, Maton PN, Oldfield EH, Streeten E, Aurbach GD, Brandi ML, Friedman E, Spiegel AM, Taggart RT, Marx SJ. Allelic loss on chromosome 11 in hereditary and sporadic tumors related to familial multiple endocrine type 1. Cancer Res 1991; 51: 1154-1157.
45. Heppner C, Kester MB, Agarwal SK, Debelenko LV, Emmert-Buck MR, Guru SC, Manickam P, Olufemi S-E, Skarulis MC, Doppman JL, Alexander RH, Kim YS, Saggar SK, Lubensky IA, Zhuang Z, Liotta LA, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ. Somatic mutation of the MEN1 gene in parathyroid tumors. Nat Genet 1997; 16: 375-378.
46. Friedman E, De Marco L, Gejman PV, Norton JA, Bale AE, Aurbach GD, Spiegel AM, Marx SJ. Allelic loss from chromosome 11 in parathyroid tumors. Cancer Res 1992; 52: 6804-6809.
47. Iwasaki H. A possible tumor suppressor gene for parathyroid adenomas. Int Surg 1996; 81: 71-76.
48. Zhuang Z, Ezzat SZ, Vortmeyer AO, Weil R, Oldfield EH, Park W-S, Pack S, Huang S, Agarwa SK, Guru SC, Manickam P, Debelenko LV, Kester MB, Olufemi S-E, Heppner C, Crabtree JS, Burns AL, Spiegel AM, Marx SJ, Chandrasekharappa SC, Collins FS, Emmert-Buck MR, Liotta LA, Asa SL, Lubensky IA. Mutations of the MEN1 tumor suppressor gene in pituitary tumors. Cancer Res 1997; 57: 5446-5451.
49. Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature 1986; 323: 643-646.
50. Hussussian CJ, Struewing JP, Goldstein AM, Higgins PA, Ally DS, Sheahan MD, Clark WH Jr, Tucker MA, Dracopoli NC. Germline p16 mutations in familial melanoma. Nat Genet 1994; 8: 15-21.
51. Srivastava S, Zou ZQ, Pirollo K, Blattner W, Chang EH. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature 1990; 348: 747-749.
52. Ginsberg AM, Raffeld M, Cossman J. Inactivation of the retinoblastoma gene in human lymphoid neoplasms. Blood 1991; 77: 833-840.
53. Imamura J, Miyoshi I, Koeffler HP. p53 in hematologic malignancies. Blood 1994; 84: 2412-2421.
54. Prokocimer M, Rotter V. Structure and function of p53 in normal cells and their aberrations in cancer cells: projection on the hematologic cell lineages. Blood 1994; 84: 2391-2411.
55. INK4B/MTS2 in human leukemias and lymphomas. Cancer Res 1995; 55: 1436-1440.
56. Orita M, Iwahana H, Kanazawa H, Hayashi K, Sekiya T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc Natl Acad Sci USA 1989; 86: 2766-2770.
57. Fearon ER. Human cancer syndromes: clues to the origin and nature of cancer. Science 1997; 278: 1043-1050.
58. Basset JHD, Forbes SA, Pannett AAJ, Lloyd SE, Christie PT, Wooding C, Harding B, Besser GM, Edwards CR, Monson JP, Sampson J, Wass JAH, Wheeler MH, Thakker RV. Characterization of mutations in patients with multiple endocrine neoplasia type 1. Am J Hum Genet 1998; 62: 232-244.
59. Karhu R, Knuutila S, Kallioniemi O-P, Siitonen S, Aine R, Vilpo L, Vilpo J. Frequent loss of the 11q14-24 region in chronic lymphocytic leukemia: a study by comparative genomic hybridization. Genes Chromosom Cancer 1997; 19: 286-290.
60. Döhner H, Stilgenbauer S, James MR, Benner A, Weilguni T, Bentz M, Fisher K, Hunstein W, Lichter P. 11q deletions identity a new subset of B-cell chronic lymphocytic leukemia characterized by extensive nodal involvement and inferior prognosis. Blood 1997; 89: 2516-2522.
61. Tomlinson IPM, Nicolai H, Solomon E, Bodmer WF. The frequency and mechanism of loss of heterozygosity on chromosome 11q in breast cancer. J Pathol 1996; 180: 38-43.
62. Gustafson CE, Young J, Leggett B, Searle J, Chevenix-Trench G. Loss of heterozygosity on the long arm of chromosome 11 in colorectal tumours. Br J Cancer 1994; 94: 395-397.
63. Healy E, Rehman I, Angus B, Rees JL. Loss of heterozygosity in sporadic cutaneous melanoma. Genes Chromosom Cancer 1995; T2: 152-156.
64. Foulkes WD, Campbell IG, Stamp GWH, Trowsdale J. Loss of heterozygosity and amplification on chromosome 11q in human ovarian cancer. Br J Cancer 1993; 67: 268-273.
65. Böni R, Vortmeyer AO, Huang S, Burg G, Hofbauer G, Zhuang Z. Mutation analysis of the MEN1 tumor suppressor gene in malignant melanoma (submitted).