-
1
-
-
0030431698
-
Microsomal ethanol oxidizing system activity by human hepatic cytochrome P450s
-
Asai H, Imaoka S. Kuroki T, Monna T and Funae Y (1996) Microsomal ethanol oxidizing system activity by human hepatic cytochrome P450s. J Pharmacol Exp Ther 227:1004-1009.
-
(1996)
J Pharmacol Exp Ther
, vol.227
, pp. 1004-1009
-
-
Asai, H.1
Imaoka, S.2
Kuroki, T.3
Monna, T.4
Funae, Y.5
-
2
-
-
0004270170
-
-
Greene Publishing Associates, New York
-
Ausubel FM, Brent R, Kingston RE. Moore DD. Seidman JG, Smith JA and Struhl K, eds (1989) Current Protocols in Molecular Biology. Greene Publishing Associates, New York.
-
(1989)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Brent, R.2
Kingston, R.E.3
Moore, D.D.4
Seidman, J.G.5
Smith, J.A.6
Struhl, K.7
-
3
-
-
0026043945
-
A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl-β-D-thiogalactopyranoside
-
Baim SB, Labow MA, Levine AJ and Shenk TA (1991) A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl-β-D-thiogalactopyranoside. Proc Natl Acad Sci USA 88:5072-5075.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5072-5075
-
-
Baim, S.B.1
Labow, M.A.2
Levine, A.J.3
Shenk, T.A.4
-
4
-
-
0028900699
-
Rabbit P450 2E1 expressed in CHO-K1 cells has a short half-life
-
Barmada S, Kienle E and Koop DR (1995) Rabbit P450 2E1 expressed in CHO-K1 cells has a short half-life. Biochem Biophys Res Commun 206:601-607.
-
(1995)
Biochem Biophys Res Commun
, vol.206
, pp. 601-607
-
-
Barmada, S.1
Kienle, E.2
Koop, D.R.3
-
5
-
-
0027465481
-
A selective transcriptional induction system for mammalian cells based on Ga14-estrogen receptor fusion proteins
-
Braselmann S, Graninger P and Busslinger M (1993) A selective transcriptional induction system for mammalian cells based on Ga14-estrogen receptor fusion proteins. Proc Natl Acad Sci USA 90:1657-1661.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1657-1661
-
-
Braselmann, S.1
Graninger, P.2
Busslinger, M.3
-
6
-
-
0030296461
-
Baculovirus expression and purification of human and rat cytochrome P450 2E1
-
Chen W, Peter RM, McArdle S, Thummel KE, Sigle RO and Nelson SD (1996) Baculovirus expression and purification of human and rat cytochrome P450 2E1. Arch Biochem Biophys 335:123-130.
-
(1996)
Arch Biochem Biophys
, vol.335
, pp. 123-130
-
-
Chen, W.1
Peter, R.M.2
McArdle, S.3
Thummel, K.E.4
Sigle, R.O.5
Nelson, S.D.6
-
7
-
-
0030749318
-
Menadione cytotoxicity to Hep G2 cells and protection by activation of nuclear factor-κB
-
Chen Q and Cederbaum AI (1997) Menadione cytotoxicity to Hep G2 cells and protection by activation of nuclear factor-κB. Mol Pharmacol 52:648-657.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 648-657
-
-
Chen, Q.1
Cederbaum, A.I.2
-
8
-
-
0031958219
-
Cytotoxicity and apoptosis produced by cytochrome P450 2El in Hep G2 cells
-
Chen Q and Cederbaum AI (1998) Cytotoxicity and apoptosis produced by cytochrome P450 2El in Hep G2 cells. Mol Pharmacol 53:638-648.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 638-648
-
-
Chen, Q.1
Cederbaum, A.I.2
-
9
-
-
0025848338
-
A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-l-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450 2D6
-
Crespi CL, Penman BW, Gelboin HV and Gonzalez FJ (1991) A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-l-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450 2D6. Carcinogenesis 12:1197-1201.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1197-1201
-
-
Crespi, C.L.1
Penman, B.W.2
Gelboin, H.V.3
Gonzalez, F.J.4
-
10
-
-
0027185531
-
Stable expression of human cytochrome P450 2E1 in Hep G2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates
-
Dai Y, Rashba-Step J and Cederbaum Al ( 1993) Stable expression of human cytochrome P450 2E1 in Hep G2 cells: Characterization of catalytic activities and production of reactive oxygen intermediates. Biochemistry 32:6928-6937.
-
(1993)
Biochemistry
, vol.32
, pp. 6928-6937
-
-
Dai, Y.1
Rashba-Step, J.2
Cederbaum, A.3
-
11
-
-
0023945548
-
Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker
-
de la Luna S, Soria I. Pulido D, Ortin J and Jimenez A (1988) Efficient transformation of mammalian cells with constructs containing a puromycin-resistance marker. Gene (Amst) 62:121-126.
-
(1988)
Gene (Amst)
, vol.62
, pp. 121-126
-
-
De La Luna, S.1
Soria, I.2
Pulido, D.3
Ortin, J.4
Jimenez, A.5
-
12
-
-
0021671419
-
Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes
-
DiMonte D. Ross D, Bellomo G, Eklow L and Orrenius S (1984a) Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch Biochem Biophys 235:334-342.
-
(1984)
Arch Biochem Biophys
, vol.235
, pp. 334-342
-
-
DiMonte, D.1
Ross, D.2
Bellomo, G.3
Eklow, L.4
Orrenius, S.5
-
14
-
-
0029121027
-
Use of tetracycline operator system to regulate oncogene expression in mammalian cells
-
Eldredge ER, Chiao PJ and Lu KP (1995) Use of tetracycline operator system to regulate oncogene expression in mammalian cells. Methods Enzymol 254:481-491.
-
(1995)
Methods Enzymol
, vol.254
, pp. 481-491
-
-
Eldredge, E.R.1
Chiao, P.J.2
Lu, K.P.3
-
15
-
-
0030587081
-
Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2
-
Gomez J, Martinez AC, Fernandez B, Garcia A and Rebollo A (1996) Critical role of Ras in the proliferation and prevention of apoptosis mediated by IL-2. J Immunol 157:2272-2281.
-
(1996)
J Immunol
, vol.157
, pp. 2272-2281
-
-
Gomez, J.1
Martinez, A.C.2
Fernandez, B.3
Garcia, A.4
Rebollo, A.5
-
16
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M and Bujard H (1992) Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89:5547-5551.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
17
-
-
0028880596
-
Cytochrome P450 2A1, 2E1, and 2C9 cDNA-expression by insect cells and partial purification using hydrophobic chromatography
-
Grogan J, Shou M, Andrusiak EA, Tamura S, Buters JT, Gonzalez FJ and Korzekwa KR (1995) Cytochrome P450 2A1, 2E1, and 2C9 cDNA-expression by insect cells and partial purification using hydrophobic chromatography. Biochem Pharmacol 50:1509-1515.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 1509-1515
-
-
Grogan, J.1
Shou, M.2
Andrusiak, E.A.3
Tamura, S.4
Buters, J.T.5
Gonzalez, F.J.6
Korzekwa, K.R.7
-
19
-
-
1842288569
-
A novel candidate tumor suppressor, INGI, is involved in the regulation of apoptosis
-
Helbing CC, Veillette C, Riabowol K, Johnston RN and Garkavtsev I (1997) A novel candidate tumor suppressor, INGI, is involved in the regulation of apoptosis. Cancer Res 57:1255-1258.
-
(1997)
Cancer Res
, vol.57
, pp. 1255-1258
-
-
Helbing, C.C.1
Veillette, C.2
Riabowol, K.3
Johnston, R.N.4
Garkavtsev, I.5
-
20
-
-
0026567713
-
Oxidative and reductive metabolism by cytochrome P450 2E1
-
Koop DR (1992) Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB J 6:724-730.
-
(1992)
FASEB J
, vol.6
, pp. 724-730
-
-
Koop, D.R.1
-
21
-
-
0028283819
-
Expoxidation of arachidonic acid as an active-site probe of cytochrome P-450 2B isoforms
-
Laethem RM, Halpert JR and Koop DR (1994) Expoxidation of arachidonic acid as an active-site probe of cytochrome P-450 2B isoforms. Biochim Biophys Acta 1206:42-48.
-
(1994)
Biochim Biophys Acta
, vol.1206
, pp. 42-48
-
-
Laethem, R.M.1
Halpert, J.R.2
Koop, D.R.3
-
22
-
-
0030935567
-
Cytochrome P-450 2E1: Its physiological and pathological role
-
Lieber CS (1997) Cytochrome P-450 2E1: Its physiological and pathological role. Physiol Rev 77:517-544.
-
(1997)
Physiol Rev
, vol.77
, pp. 517-544
-
-
Lieber, C.S.1
-
23
-
-
0031947060
-
Heterologous expression of rat P450 2E1 in a mammalian cell line: In situ metabolism and cytotoxicity of N-nitrosodimethylamine
-
Lin HL, Roberts ES and Hollenberg PF (1998) Heterologous expression of rat P450 2E1 in a mammalian cell line: In situ metabolism and cytotoxicity of N-nitrosodimethylamine Carcinogenesis 19:321-329.
-
(1998)
Carcinogenesis
, vol.19
, pp. 321-329
-
-
Lin, H.L.1
Roberts, E.S.2
Hollenberg, P.F.3
-
24
-
-
0027158167
-
Mammalian PC-12 cell genetically engineered for human cytochrome P450 2E1 expression
-
Mapoles J, Berthou F, Alexander A, Simon F and Menez JF (1993) Mammalian PC-12 cell genetically engineered for human cytochrome P450 2E1 expression. Eur J Biochem 214:735-745.
-
(1993)
Eur J Biochem
, vol.214
, pp. 735-745
-
-
Mapoles, J.1
Berthou, F.2
Alexander, A.3
Simon, F.4
Menez, J.F.5
-
25
-
-
0020328232
-
The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells
-
Mayo KE, Warren R and Palmiter RD (1982) The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells. Cell 29:99-108.
-
(1982)
Cell
, vol.29
, pp. 99-108
-
-
Mayo, K.E.1
Warren, R.2
Palmiter, R.D.3
-
26
-
-
0028856361
-
Ethanol increase cytochrome P4502E1 and induces oxidative stress in astrocytes
-
Montoliu C, Sancho-Tello M, Azorin I, Burgal M, Valles S, Renau-Piqueras J and Guerri C (1995) Ethanol increase cytochrome P4502E1 and induces oxidative stress in astrocytes. J Neurochem 65:2561-2570.
-
(1995)
J Neurochem
, vol.65
, pp. 2561-2570
-
-
Montoliu, C.1
Sancho-Tello, M.2
Azorin, I.3
Burgal, M.4
Valles, S.5
Renau-Piqueras, J.6
Guerri, C.7
-
27
-
-
0028051780
-
Fish oil, alcohol, and liver pathology: Role of cytochrome P450 2E1
-
Morimoto M, Zern MA, Hagbjork AL, Ingelman-Sundberg M and French SW (1994) Fish oil, alcohol, and liver pathology: Role of cytochrome P450 2E1. Proc Soc Exp Biol Med 207:197-205.
-
(1994)
Proc Soc Exp Biol Med
, vol.207
, pp. 197-205
-
-
Morimoto, M.1
Zern, M.A.2
Hagbjork, A.L.3
Ingelman-Sundberg, M.4
French, S.W.5
-
28
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
Mosmann T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays J Immunol Methods 65:55-63.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
29
-
-
0030575551
-
Stable expression of human CYP2E1 in Chinese hamster cells: High sensitivity to N,N-dimethylnitrosamine in cytotoxicity testing
-
Nakagawa T, Sawada M, Gonzalez FJ, Yokoi T and Kamataki T (1996) Stable expression of human CYP2E1 in Chinese hamster cells: High sensitivity to N,N-dimethylnitrosamine in cytotoxicity testing. Mutat Res 360:181-186.
-
(1996)
Mutat Res
, vol.360
, pp. 181-186
-
-
Nakagawa, T.1
Sawada, M.2
Gonzalez, F.J.3
Yokoi, T.4
Kamataki, T.5
-
30
-
-
0026773251
-
Stable expression of human cytochrome P450IIE1 in mammalian cells: Metabolic activation of nitrosodimethylamine and formation of adducts with cellular DNA
-
Nouso K, Thorgeirsson SS and Battula N (1992) Stable expression of human cytochrome P450IIE1 in mammalian cells: Metabolic activation of nitrosodimethylamine and formation of adducts with cellular DNA. Cancer Res 52:1796-1800.
-
(1992)
Cancer Res
, vol.52
, pp. 1796-1800
-
-
Nouso, K.1
Thorgeirsson, S.S.2
Battula, N.3
-
31
-
-
0028997743
-
Chlorzoxazone is metabolized by human CYP1 A2 as well as by human CYP2E1
-
Ono S, Hatanaka T, Hotta H, Tsutsui M, Satoh T and Gonzalez FJ (1995) Chlorzoxazone is metabolized by human CYP1 A2 as well as by human CYP2E1. Pharmacogenetics 5:143-150.
-
(1995)
Pharmacogenetics
, vol.5
, pp. 143-150
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Tsutsui, M.4
Satoh, T.5
Gonzalez, F.J.6
-
32
-
-
0030465547
-
Diffuse brain invasion of glioma cells requires b1 integrins
-
Paulus W, Baur I, Beutler AS and Reeves SA (1996) Diffuse brain invasion of glioma cells requires b1 integrins. Lab Invest 75:819-826.
-
(1996)
Lab Invest
, vol.75
, pp. 819-826
-
-
Paulus, W.1
Baur, I.2
Beutler, A.S.3
Reeves, S.A.4
-
33
-
-
0026344778
-
Expression of mammalian P450s in Escherichia Coli
-
Porter TD and Larson JR (1991) Expression of mammalian P450s in Escherichia Coli. Methods Enzymol 206:108-116.
-
(1991)
Methods Enzymol
, vol.206
, pp. 108-116
-
-
Porter, T.D.1
Larson, J.R.2
-
34
-
-
0027218413
-
Increased NADPH-dependent, and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment
-
Rashba-Step J, Turro NJ and Cederbaum AI (1993) Increased NADPH-dependent, and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment. Arch Biochem Biophys 300:401-408.
-
(1993)
Arch Biochem Biophys
, vol.300
, pp. 401-408
-
-
Rashba-Step, J.1
Turro, N.J.2
Cederbaum, A.I.3
-
35
-
-
0029618909
-
Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1
-
Robert BJ, Song BJ, Soh Y, Park SS and Shoaf SE (1995) Ethanol induces CYP2E1 by protein stabilization. Role of ubiquitin conjugation in the rapid degradation of CYP2E1. J Biol Chem 270:29632-29635.
-
(1995)
J Biol Chem
, vol.270
, pp. 29632-29635
-
-
Robert, B.J.1
Song, B.J.2
Soh, Y.3
Park, S.S.4
Shoaf, S.E.5
-
36
-
-
0028981769
-
Stable expression of human cytochrome P450 2E1 in V79 Chinese hamster cells
-
Schmalix WA, Barrenscheen M, Landsiedel R, Janzowski C, Eisenbrand G, Gonzalez F, Eliasson E, Ingelman-Sundberg M, Perchermeier M, Greim H and Doehmer J (1995) Stable expression of human cytochrome P450 2E1 in V79 Chinese hamster cells. Eur J Pharmacol 293:123-131.
-
(1995)
Eur J Pharmacol
, vol.293
, pp. 123-131
-
-
Schmalix, W.A.1
Barrenscheen, M.2
Landsiedel, R.3
Janzowski, C.4
Eisenbrand, G.5
Gonzalez, F.6
Eliasson, E.7
Ingelman-Sundberg, M.8
Perchermeier, M.9
Greim, H.10
Doehmer, J.11
-
37
-
-
0022508442
-
Kinetic and equilibrium characterization of the Tet repressor-tetracycline complex by fluorescence measurements. Evidence for divalent metal ion requirement and energy transfer
-
Takahashi M, Altschmied L and Hillen W (1986) Kinetic and equilibrium characterization of the Tet repressor-tetracycline complex by fluorescence measurements. Evidence for divalent metal ion requirement and energy transfer. J Mol Biol 187:341-348.
-
(1986)
J Mol Biol
, vol.187
, pp. 341-348
-
-
Takahashi, M.1
Altschmied, L.2
Hillen, W.3
-
38
-
-
0023853836
-
Cytochrome P-450-dependent oxidase activity and hydroxyl radical production in micellar and membranous types of reconstituted systems
-
Terelius Y and Ingelman-Sundberg M (1988) Cytochrome P-450-dependent oxidase activity and hydroxyl radical production in micellar and membranous types of reconstituted systems. Biochem Pharmacol 37:1383-1389.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1383-1389
-
-
Terelius, Y.1
Ingelman-Sundberg, M.2
-
39
-
-
0026546019
-
Degradation of cytochrome P450 2E1: Selective loss after labilization of the enzyme
-
Tierney DJ, Haas AL and Koop DR (1992) Degradation of cytochrome P450 2E1: Selective loss after labilization of the enzyme. Arch Biochem Biophys 293:9-16.
-
(1992)
Arch Biochem Biophys
, vol.293
, pp. 9-16
-
-
Tierney, D.J.1
Haas, A.L.2
Koop, D.R.3
-
40
-
-
0030588264
-
Expression and coupling of human cytochrome P450 2E1 and NADPH-cytochrome P450 oxidoreductase in dual expression and co-infection system with baculovirus in insect cells
-
Wang MH, Patten CJ, Yang GY, Paranawithana SR, Tan Y and Yang CS (1996) Expression and coupling of human cytochrome P450 2E1 and NADPH-cytochrome P450 oxidoreductase in dual expression and co-infection system with baculovirus in insect cells. Arch Biochem Biophys 334:380-388.
-
(1996)
Arch Biochem Biophys
, vol.334
, pp. 380-388
-
-
Wang, M.H.1
Patten, C.J.2
Yang, G.Y.3
Paranawithana, S.R.4
Tan, Y.5
Yang, C.S.6
-
41
-
-
0022975115
-
Characterization of ethanol-inducible human liver N-nitrosodimethylamine demethylase
-
Wrighton SA, Thomas PE and Molowa DT (1986) Characterization of ethanol-inducible human liver N-nitrosodimethylamine demethylase. Biochemistry 25:6731-6735.
-
(1986)
Biochemistry
, vol.25
, pp. 6731-6735
-
-
Wrighton, S.A.1
Thomas, P.E.2
Molowa, D.T.3
-
42
-
-
0021958785
-
Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes
-
Yang CS, Tu YY, Koop DR and Coon MJ (1985) Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes. Cancer Res 45:1140-1145.
-
(1985)
Cancer Res
, vol.45
, pp. 1140-1145
-
-
Yang, C.S.1
Tu, Y.Y.2
Koop, D.R.3
Coon, M.J.4
-
43
-
-
0031149527
-
Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
-
Yang MX and Cederbaum AI (1997) Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1 Arch Biochem Biophys 341:25-33.
-
(1997)
Arch Biochem Biophys
, vol.341
, pp. 25-33
-
-
Yang, M.X.1
Cederbaum, A.I.2
-
44
-
-
0029866655
-
Tetracycline-controlled gene expression system achieves high-level and quantitative control of gene expression
-
Yin DX, Zhu L and Schimke RT (1996) Tetracycline-controlled gene expression system achieves high-level and quantitative control of gene expression. Anal Biochem 235:195-201.
-
(1996)
Anal Biochem
, vol.235
, pp. 195-201
-
-
Yin, D.X.1
Zhu, L.2
Schimke, R.T.3
|