메뉴 건너뛰기




Volumn 13, Issue 4, 1999, Pages 249-258

Raloxifene analog LY 117018 effects on central and peripheral β-endorphin

Author keywords

LY 117018; Raloxifene; SERMs; endorphin

Indexed keywords

6 HYDROXY 2 (4 HYDROXYPHENYL) 3 [4 [2 (1 PYRROLIDINYL)ETHOXY]BENZOYL]BENZO[B]THIOPHENE; ANTIESTROGEN; BETA ENDORPHIN; ESTRADIOL; ESTROGEN RECEPTOR;

EID: 0032887292     PISSN: 09513590     EISSN: None     Source Type: Journal    
DOI: 10.3109/09513599909167563     Document Type: Article
Times cited : (32)

References (36)
  • 1
    • 0002395353 scopus 로고    scopus 로고
    • The complexity of selective estrogen receptor modulators: The design of a postmenopausal prevention maintenance therapy
    • Lindsay R, Dempster DW, Jordan VC, eds. Philadelphia: Lippincott-Raven Publishers
    • MacGregor JI, Tonetti DA, Jordan VC. The complexity of selective estrogen receptor modulators: the design of a postmenopausal prevention maintenance therapy. In Lindsay R, Dempster DW, Jordan VC, eds. Estrogens and Antiestrogens. Philadelphia: Lippincott-Raven Publishers, 1997:261-77
    • (1997) Estrogens and Antiestrogens , pp. 261-277
    • MacGregor, J.I.1    Tonetti, D.A.2    Jordan, V.C.3
  • 2
    • 0030801841 scopus 로고    scopus 로고
    • Differential ligand activation of estrogen receptor ERα and ERβ at AP1 sites
    • Paech K, Webb P, Kuiper GJM, et al. Differential ligand activation of estrogen receptor ERα and ERβ at AP1 sites. Science 1997;277:1508-10
    • (1997) Science , vol.277 , pp. 1508-1510
    • Paech, K.1    Webb, P.2    Kuiper, G.J.M.3
  • 3
    • 0031816540 scopus 로고    scopus 로고
    • Differential response of ERα and ERβ to partial estrogen agonists/antagonists
    • Barkhem T, Carlsson B, Nilsson Y, et al. Differential response of ERα and ERβ to partial estrogen agonists/antagonists. Mol Pharmacol 1998;54:105-12
    • (1998) Mol Pharmacol , vol.54 , pp. 105-112
    • Barkhem, T.1    Carlsson, B.2    Nilsson, Y.3
  • 4
    • 0032487057 scopus 로고    scopus 로고
    • Expression and neuropeptidergic characterization of estrogen receptors (ERα and ERβ)throughout the rat brain: Anatomical evidence of distinct roles of each subtype
    • Laflamme N, Nappi RE, Drolet G, et al. Expression and neuropeptidergic characterization of estrogen receptors (ERα and ERβ)throughout the rat brain: anatomical evidence of distinct roles of each subtype. J Neurobiol 1998;36:357-78
    • (1998) J Neurobiol , vol.36 , pp. 357-378
    • Laflamme, N.1    Nappi, R.E.2    Drolet, G.3
  • 5
    • 0030665761 scopus 로고    scopus 로고
    • Regulation of progesterone receptor messenger ribonucleic acid in the rat medial preoptic nucleus by estrogenic and anti-estrogenic compounds: An in situ hybridization study
    • Shughruc PJ, Lane MV, Merchenthaler I, Regulation of progesterone receptor messenger ribonucleic acid in the rat medial preoptic nucleus by estrogenic and anti-estrogenic compounds: an in situ hybridization study. Endocrinology 1997;138:5476-84
    • (1997) Endocrinology , vol.138 , pp. 5476-5484
    • Shughruc, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 6
    • 0030467582 scopus 로고    scopus 로고
    • The distribution of estrogen receptor-beta mRNA in the rat hypothalamus
    • Shughrue PJ, Komm B, Merchenthaler I. The distribution of estrogen receptor-beta mRNA in the rat hypothalamus. Steroids 1996;61:678-81
    • (1996) Steroids , vol.61 , pp. 678-681
    • Shughrue, P.J.1    Komm, B.2    Merchenthaler, I.3
  • 7
    • 0025991237 scopus 로고
    • Phase I study of toremifene in patients wth advanced cancer
    • Hamm JT, Tormey DC, Kohler PC, et al. Phase I study of toremifene in patients wth advanced cancer. J Clin Oncol 1991;9:2036-41
    • (1991) J Clin Oncol , vol.9 , pp. 2036-2041
    • Hamm, J.T.1    Tormey, D.C.2    Kohler, P.C.3
  • 8
    • 0028288381 scopus 로고
    • Influence of toremifene on the endocrine regulation in breast cancer patients
    • Szamel I, Hindy I, Vincze B, et al. Influence of toremifene on the endocrine regulation in breast cancer patients. Eur J Cancer 1994;30:154-8
    • (1994) Eur J Cancer , vol.30 , pp. 154-158
    • Szamel, I.1    Hindy, I.2    Vincze, B.3
  • 9
    • 0023677286 scopus 로고
    • Inhibitory actions of keoxifene on luteinizing hormone secretion in pituitary gonadotrophs
    • Ortmann O, Emons G, Knuppen R, et al. Inhibitory actions of keoxifene on luteinizing hormone secretion in pituitary gonadotrophs. Endocrinology 1988;123:962-8
    • (1988) Endocrinology , vol.123 , pp. 962-968
    • Ortmann, O.1    Emons, G.2    Knuppen, R.3
  • 10
    • 0020582094 scopus 로고
    • Effects of a new anti-estrogen, Keoxifene LY156758, on growth of carcinogen induced mammary tumors and on LH and prolactin levels
    • Clemens JA, Bennett DR, Black LJ, et al. Effects of a new anti-estrogen, Keoxifene LY156758, on growth of carcinogen induced mammary tumors and on LH and prolactin levels. Life Sci 1983:2869-75
    • (1983) Life Sci , pp. 2869-2875
    • Clemens, J.A.1    Bennett, D.R.2    Black, L.J.3
  • 11
    • 0026555809 scopus 로고
    • Anti-estrogen binding sites in brain and pituitary of ovariectomized rats
    • Gray JM, Ziemian L. Anti-estrogen binding sites in brain and pituitary of ovariectomized rats. Brain Res 1992;578:55-60
    • (1992) Brain Res , vol.578 , pp. 55-60
    • Gray, J.M.1    Ziemian, L.2
  • 12
    • 0024544402 scopus 로고
    • Suppression of spontaneous LH surges in estrogen treated ovariectomized rats by microimplants of antiestrogens into the preoptic brain
    • Petersen SL, Barraclough CA. Suppression of spontaneous LH surges in estrogen treated ovariectomized rats by microimplants of antiestrogens into the preoptic brain. Brain Res 1989;484:279-89
    • (1989) Brain Res , vol.484 , pp. 279-289
    • Petersen, S.L.1    Barraclough, C.A.2
  • 13
    • 0023114871 scopus 로고
    • Antagonism of sexual behaviour in Female rats by ventromedial hypothalamic implants of anti-estrogen
    • Meisel RL, Dohanich GP, McEwen BS, et al. Antagonism of sexual behaviour in Female rats by ventromedial hypothalamic implants of anti-estrogen. Neuroendocrinology 1987;45:201-7
    • (1987) Neuroendocrinology , vol.45 , pp. 201-207
    • Meisel, R.L.1    Dohanich, G.P.2    McEwen, B.S.3
  • 14
    • 0026595133 scopus 로고
    • Systemic treatment of early breast cancer by hormonal, cytotoxic or immune therapy
    • Early Breast Cancer Trials Collaborative Group. Systemic treatment of early breast cancer by hormonal, cytotoxic or immune therapy. Lancet 1992;339:71-85
    • (1992) Lancet , vol.339 , pp. 71-85
  • 15
    • 0032538822 scopus 로고    scopus 로고
    • The effect of estrogens and anti-estrogens in a rat model for hot flush
    • Merchenthaler I, Funkhouser JM, Carver JM, et al. The effect of estrogens and anti-estrogens in a rat model for hot flush. Maturitas 1998;30:307-16
    • (1998) Maturitas , vol.30 , pp. 307-316
    • Merchenthaler, I.1    Funkhouser, J.M.2    Carver, J.M.3
  • 16
    • 0031797494 scopus 로고    scopus 로고
    • Raloxifene induces neurite outgrowth in estrogen receptor positive PC12 cells
    • Nilsen J, Mor G, Naftolin F. Raloxifene induces neurite outgrowth in estrogen receptor positive PC12 cells. Menopause 1998;5:211-16
    • (1998) Menopause , vol.5 , pp. 211-216
    • Nilsen, J.1    Mor, G.2    Naftolin, F.3
  • 17
    • 0001775922 scopus 로고
    • Opioid control of gonadotropin secretion
    • Genazzani AR, Montemagno U, Nappi C, et al, eds. Carnforth, UK: Parthenon Publishing
    • Petraglia F, Panerai AE, Rivier C, et al. Opioid control of gonadotropin secretion. In Genazzani AR, Montemagno U, Nappi C, et al, eds. The Brain and Female Reproductive Function Carnforth, UK: Parthenon Publishing, 1987:65-71
    • (1987) The Brain and Female Reproductive Function , pp. 65-71
    • Petraglia, F.1    Panerai, A.E.2    Rivier, C.3
  • 18
    • 0009796307 scopus 로고
    • Dual effects of the opioids in the control of gonadotropin secretion
    • Delitala G, Motta M, Serio M, eds. New York: Raven Press
    • Piva F, Limonta P, Maggi R, et al. Dual effects of the opioids in the control of gonadotropin secretion. In Delitala G, Motta M, Serio M, eds. Opiod Modulation of Endocrine Function. New York: Raven Press, 1984:155-9
    • (1984) Opiod Modulation of Endocrine Function , pp. 155-159
    • Piva, F.1    Limonta, P.2    Maggi, R.3
  • 19
    • 0002004636 scopus 로고
    • Gonadal steroid modulation of brain and pituitary β-endorphin
    • Camanni F and Muller EE, eds. New York: Raven Press
    • Locatelli V, Petraglia F. Gonadal steroid modulation of brain and pituitary β-endorphin. In Camanni F and Muller EE, eds. Pituitary Hyperfunction: Physiopathology and Clinical Aspects. New York: Raven Press, 1984:35-40
    • (1984) Pituitary Hyperfunction: Physiopathology and Clinical Aspects , pp. 35-40
    • Locatelli, V.1    Petraglia, F.2
  • 20
    • 0022638960 scopus 로고
    • Estradiol target sites immunoreactive for β-endorphin in the arcuate nucleus of rat and mouse hypothalamus
    • Jirikowski GF, Merchenthaler I, Rieger GE, et al. Estradiol target sites immunoreactive for β-endorphin in the arcuate nucleus of rat and mouse hypothalamus, Neurosci Lett 1986;65:121-5
    • (1986) Neurosci Lett , vol.65 , pp. 121-125
    • Jirikowski, G.F.1    Merchenthaler, I.2    Rieger, G.E.3
  • 21
    • 0025317757 scopus 로고
    • Effects of steroid hormones and antihormones on hypothalamic β-endorphin concentrations in intact and castrated female rats
    • Genazzani AR, Petraglia F, Mercuri N. et al. Effects of steroid hormones and antihormones on hypothalamic β-endorphin concentrations in intact and castrated female rats. J Endocrinol Invest 1990;13:91-6
    • (1990) J Endocrinol Invest , vol.13 , pp. 91-96
    • Genazzani, A.R.1    Petraglia, F.2    Mercuri, N.3
  • 22
    • 0020202031 scopus 로고
    • Effect of gonadectomy and gonadal steroid replacement on pituitary and plasma β-endorphin levels in rats
    • Petraglia F, Penalva A, Locatelli V, et al. Effect of gonadectomy and gonadal steroid replacement on pituitary and plasma β-endorphin levels in rats. Endocrinology 1982;111:1224-9
    • (1982) Endocrinology , vol.111 , pp. 1224-1229
    • Petraglia, F.1    Penalva, A.2    Locatelli, V.3
  • 23
    • 0017184389 scopus 로고
    • A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. A rapid and sensitive method for quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Annal Biochem 1976;72:248-59
    • (1976) Annal Biochem , vol.72 , pp. 248-259
    • Bradford, M.1
  • 25
    • 0022629696 scopus 로고
    • Oestrus cycle-related LH responsiveness to naloxone: Effect of high oestrogen levels on the activity of opioid receptors
    • Petraglia F, Locatelli V, Facchinetti F, et al. Oestrus cycle-related LH responsiveness to naloxone: effect of high oestrogen levels on the activity of opioid receptors J Endorcrinol 1986;108:89-94
    • (1986) J Endorcrinol , vol.108 , pp. 89-94
    • Petraglia, F.1    Locatelli, V.2    Facchinetti, F.3
  • 26
    • 0019353270 scopus 로고
    • Changes in the β-endorphin content of discrete hypothalamic nuclei during the estrous cycle of the rat
    • Barden N, Merand Y, Rouleau D, et al. Changes in the β-endorphin content of discrete hypothalamic nuclei during the estrous cycle of the rat. Brain Res 1981;204:441-5
    • (1981) Brain Res , vol.204 , pp. 441-445
    • Barden, N.1    Merand, Y.2    Rouleau, D.3
  • 27
    • 0020554666 scopus 로고
    • Changes in β-endorphin content in discrete areas of the hypothalamus throughout proestrus and diestrus of the rat
    • Knuth UA, Sikand GS, Casanueva FF, et al. Changes in β-endorphin content in discrete areas of the hypothalamus throughout proestrus and diestrus of the rat. Life Sci 1983;33:1443-50
    • (1983) Life Sci , vol.33 , pp. 1443-1450
    • Knuth, U.A.1    Sikand, G.S.2    Casanueva, F.F.3
  • 28
    • 0021135530 scopus 로고
    • Increase of pro-opiomelanocortin related peptides during subjective menopausal flushes
    • Genazzani AR, Petraglia F, Facchinetti F, et al. Increase of pro-opiomelanocortin related peptides during subjective menopausal flushes. Am J Obstet Gynecol 1984;149:775-9
    • (1984) Am J Obstet Gynecol , vol.149 , pp. 775-779
    • Genazzani, A.R.1    Petraglia, F.2    Facchinetti, F.3
  • 29
    • 0019481072 scopus 로고
    • Climacteric flushing: Clinical and endocrine response to infusion of naloxone
    • Linghtman SL, Jacobs HS, Maguire AK. Climacteric flushing: clinical and endocrine response to infusion of naloxone. Br J Obstet Gynecol 1981;88:919-24
    • (1981) Br J Obstet Gynecol , vol.88 , pp. 919-924
    • Linghtman, S.L.1    Jacobs, H.S.2    Maguire, A.K.3
  • 30
    • 0031573927 scopus 로고    scopus 로고
    • Neuroendocrine effects of different oestradiol-progestin regimens in postmenopausal women
    • Stomati M, Bersi C, Rubino S, et al. Neuroendocrine effects of different oestradiol-progestin regimens in postmenopausal women. Maturitas 1997;28:127-35
    • (1997) Maturitas , vol.28 , pp. 127-135
    • Stomati, M.1    Bersi, C.2    Rubino, S.3
  • 32
    • 0024993176 scopus 로고
    • Estrogens modulate the circadian rhythm of hypothalamic β-endorphin contents in female rats
    • Genazzani AR, Trentini GP, Petraglia F, et al. Estrogens modulate the circadian rhythm of hypothalamic β-endorphin contents in female rats. Neuroendocrinology 1990;52:221-4
    • (1990) Neuroendocrinology , vol.52 , pp. 221-224
    • Genazzani, A.R.1    Trentini, G.P.2    Petraglia, F.3
  • 33
    • 0023301723 scopus 로고
    • Progesterone and progestins modulate β-endorphin concentrations in the hypothalamus and in pituitary of castrated female rats
    • Genazzani AR, Petraglia F, Bergamaschi M, et al. Progesterone and progestins modulate β-endorphin concentrations in the hypothalamus and in pituitary of castrated female rats. Gynecol Endocrinol 1987;1:61-9
    • (1987) Gynecol Endocrinol , vol.1 , pp. 61-69
    • Genazzani, A.R.1    Petraglia, F.2    Bergamaschi, M.3
  • 34
    • 0002498147 scopus 로고
    • Progesterone and progestins modulate hypothalamic and pituitary β-endorphin
    • Runnebaum B, Rabe T, Kiesel L, eds. Berlin, Heidelberg: Springer-Verlag
    • Genazzani AR, Petraglia F, Bergamaschi M, et al. Progesterone and progestins modulate hypothalamic and pituitary β-endorphin. In Runnebaum B, Rabe T, Kiesel L, eds. Female Contraception. Berlin, Heidelberg: Springer-Verlag, 1988:167-72
    • (1988) Female Contraception , pp. 167-172
    • Genazzani, A.R.1    Petraglia, F.2    Bergamaschi, M.3
  • 35
    • 0023065513 scopus 로고
    • Effects of Org OD 14 on pituitary and peripheral β-endorphin in castrated rats and postmenopausal women
    • Genazzani AR, Petraglia F, Facchinetti F, et al. Effects of Org OD 14 on pituitary and peripheral β-endorphin in castrated rats and postmenopausal women. Maturitas 1987;1(Suppl):35-48
    • (1987) Maturitas , vol.1 , Issue.SUPPL. , pp. 35-48
    • Genazzani, A.R.1    Petraglia, F.2    Facchinetti, F.3
  • 36
    • 0021201213 scopus 로고
    • Antiestrogens. Structure-activity studies in a series of 3-aroyl-2-arylbenzolbthiophene derivatives leading to LY 156758, a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity
    • Jones CD, Jevnikar MG, Pick AJ, et al. Anti-estrogens. Structure-activity studies in a series of 3-aroyl-2-arylbenzolbthiophene derivatives leading to LY 156758, a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity. J Med Chem 1984;27:1057-66
    • (1984) J Med Chem , vol.27 , pp. 1057-1066
    • Jones, C.D.1    Jevnikar, M.G.2    Pick, A.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.