Estimation of SELEX pool size by measurement of DNA renaturation rates

RNA

Volumn 5, Issue 10, 1999, Pages 1326-1332

  Charlton, Josephine ^a   Smith, Drew ^a  

^a GILEAD SCIENCES   (United States)

Author keywords

Aptamers; DNA hybridization

Indexed keywords

DNA;

ARTICLE; DNA HYBRIDIZATION; DNA SEQUENCE; GENOME; NUCLEIC ACID RENATURATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

DNA; DNA, VIRAL; GENETIC TECHNIQUES; NUCLEIC ACID RENATURATION; PLASMIDS; POLYMERASE CHAIN REACTION; TEMPERATURE;

EID: 0032884387     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838299991021     Document Type: Article

References (13)

1. Bartel DP, Szostak JW. 1993. Isolation of new ribozymes from a large pool of random sequences. Science 261:1411-1418.
2. Britten R, Kohne D. 1968. Repeated sequences in DNA. Science 161:529-540.
3. Burke DH, Willis JH. 1998. Recombination, RNA evolution, and bifunctional RNA molecules isolated through chimeric SELEX. RNA 4:1165-1175.
4. Cantor CR, Schimmel P. 1980. Biophysical chemistry. New York: WH Freeman & Co.
5. Charlton J, Kirschenheuter GP, Smith D. 1997. Highly potent irreversible inhibitors of neutrophil elastase generated by selection from a randomized DNA-valine phosphonate library. Biochemistry 36:3018-3026.
6. Eisenberg D, Crothers D. 1979. Physical chemistry. Menlo Park, Caifornia: The Benjamin/Cummings Publishing Company, Inc.
7. Ellington AD, Szostak JW. 1990. In vitro selection of RNA molecules that bind specific ligands. Nature 346:818-822.
8. Irvine D, Tuerk C, Gold L. 1991. SELEXION. Systematic evolution of ligands by exponential enrichment with integrated optimization by non-linear analysis. J Mol Biol 222:739-761.
9. Marmur J, Doty P. 1962. Determination of the base composition of deoxyribonucleic acid from its thermal denaturation temperature. J Mol Biol 5:109-118.
10. Pontius B, Berg P. 1991. Rapid renaturation of complementary DNA strands mediated by cation detergents: A role for high-probability binding domains in enhancing the kinetics of molecular assembly processes. Proc Natl Acad Sci USA 88:8237-8241.
11. Tuerk C, Gold L. 1990. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249:505-510.
12. Vant-Hull B, Payano-Baez A, Davis RH, Gold L. 1998. The mathematics of SELEX against complex targets. J Mol Biol 278:579-597.
13. Wilson C, Szostak JW. 1995. In vitro evolution of a self-alkylating ribozyme. Nature 374:777-782.