Elevated CD154 (CD40 ligand) synthesis in T-cells from allergic patients after nonspecific stimulation in vitro

Journal of Investigational Allergology and Clinical Immunology

Volumn 9, Issue 4, 1999, Pages 248-252

  Markert, U R ^a   Bar C ^a   Niess, J H ^a   Vogelsang, H ^a   Zwacka, G ^b  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b Kinderklinik Robert Koch Krankhs   (Germany)

Author keywords

Allergy; B cells; CD154; CD40; CD40 ligand; T cells

Indexed keywords

GLYCOPROTEIN GP 39; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE;

ALLERGY; ARTICLE; CELL SEPARATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTER; GRASS POLLEN; HOUSE DUST ALLERGY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; POLLEN ALLERGY; PROTEIN SYNTHESIS; T LYMPHOCYTE;

CD40 LIGAND; CELL SEPARATION; CHILD; FEMALE; FLOW CYTOMETRY; HUMANS; HYPERSENSITIVITY; MALE; MEMBRANE GLYCOPROTEINS; T-LYMPHOCYTES;

EID: 0032884109     PISSN: 10189068     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Banchereau, J., Bazan, F., Blanchard, D., Briere, F., Galizzi, J.P., van-Kooten, C., Liu, Y.J., Rousset, F., Saeland, S. The CD40 antigen and its ligand. Annu Rev Immunol 1994, 12: 881-992.
2. Fuleihan, R., Ahern, D., Geha, R S. CD40 ligand expression is developmentally regulated in human thymocytes. Clin Immunol Immunopathol 1995, 76: 52-8.
3. Mingari, M.C., Maggi, E., Cambiaggi, A., Annunziato, F., Schiavetti, F., Manetti, R., Moretta, L., Romagnani, S. Development in vitro of human CD4+ thymocytes into functionally mature Th2 cells. Exogenous interleukin-12 is required for priming thymocytes to produce both Th1 cytokines 4nd interleukin-10. Eur J Immunol 1996, 26: 1083-7.
4. Splawski, J.B., Nishloka, J., Nishloka, Y., Lipsky, P.E. CD40 ligand is expressed and functional on activated neonatal T cells. J Immunol 1996; 156: 119-27.
5. Noelle, R.J., Ledbetter, J.A., Aruffo, A. CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. Immunol Today 1992, 13: 431-3.
6. Callard, R.E., Armitage, R J., Fanslow, W.C., Spriggs, M.K. CD40 ligand and its role in X-linked hyper-IgM syndrome. Immunol Today 1993, 14: 559-64
7. Armitage, R.J., Macduff, B.M., Spriggs, M.K., Fanslow, W C. Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. Immunol 1993, 160 3671-80.
8. Hollenbaugh, D., Ochs, H.D., Noelle, R.J., Ledbetter, J.A., Aruffo, A. The role of CD40 and its ligand in the regulation of the immune response. Immunol Rev 1994, 138: 23-37.
9. Grewal, I.S., Foollmer, H.G , Grewal, K.D., Xu, J., Hardardottir, F., Baron, J.L., Janeway, Jr. C A., Flavell, R.A Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis. Science 1996, 273: 1864-7.
10. Roy, M , Aruffo, A., Ledbetter, J.A., Linsley, P., Kehry, M., Noelle, R.J. Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses. Eur J Immunol 1995, 25: 596-603.
11. Van Essen, D., Kikutani, H., Gray, D. CD40 ligand-transduced co-stimulation of T cells in the development of helper function. Nature 1995, 378: 620-3.
12. Van Kooten, C., Banchereau, J. CD40-CD40 ligand. A multifunctional receptor-ligand pair. Adv Immunol 1996, 61 1-77
13. Van Kooten, C., Banchereau, J. Immune regulation by CD40-CD40-L interactions. Front Blosci 1997, 1: D1-D11.
14. Burdin, N., Van Kooten, C., Galibert, L., Abrams, J.S., Wijdenes, J., Banchereau, J., Rousset, F Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 1995, 154. 2633-44.
15. Malisan, F., Briere, F, Bridon, J.M., Harindranath, N., Mills, F.C., Max, E.E., Banchereau, J., Martinez-Valdez, H. Interleukin-10 induces immunoglobulin G isotype switch recombination in human CD40-activated naive B lymphocytes. J Exp Med 1996, 183: 937-47.
16. Kroczek, R.A., Graf, D., Brugnoni, D., Giliani, S., Korthuer, U., Ugazio, A., Senger, G., Mages, H.W., Villa, A., Notarangelo, L.D. Defective expression of CD40 ligand on T cells causes "X-linked immunodeficiency with hyper-IgM (HIGM1)". Immunol Rev 1994, 138: 39-59.
17. Blotta, M.H., Marshall, J.D., DeKruyff, R.H., Umetsu, D.T. Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis. J Immunol 1996, 156: 3133-40.
18. Peng, X., Kasran, A., Warmerdam, P.A.M., De Boer, M., Ceuppens, J.L. Accessory signaling by CD40 for T cell activation: Induction of Th1 and Th2 cytokines and synergy with interleukin-12 for interferon-gamma production. Eur J Immunol 1996, 26: 1621-7.
19. Hermes, B., Worm, M., Nowak, F., Krozcek, R.A., Stein, H., Henz, B.M. Upregulation of CD40 and CD40 ligand expression in IgE-associated cutaneous diseases. Acta Derm Venereol 1997, 77: 441-5.
20. Burdin, N., Gailbert, L., Garrone, P., Durand, I., Banchereau, J., Roussel, F. Inability to produce IL-6 is a functional feature of human germinal B cells. 1996, 156: 4107-13.