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Volumn 5, Issue 9, 1999, Pages 2399-2408

A pilot study of interferon α-2a, fluorouracil, and leucovorin given with granulocyte-macrophage colony stimulating factor in advanced gastrointestinal adenocarcinoma

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; FOLINIC ACID; RECOMBINANT ALPHA2A INTERFERON; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

EID: 0032883417     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (7)

References (45)
  • 1
    • 33745464490 scopus 로고
    • Fluorinated pyrimidines: A new class of tumor inhibitory compounds
    • Heidelberger, C., Chaudhuari, N. K., and Danenberg, P. Fluorinated pyrimidines: a new class of tumor inhibitory compounds. Nature (Lond.), 179: 663-666, 1957.
    • (1957) Nature (Lond.) , vol.179 , pp. 663-666
    • Heidelberger, C.1    Chaudhuari, N.K.2    Danenberg, P.3
  • 2
    • 0002548405 scopus 로고    scopus 로고
    • Fluorinated pyrimidines
    • B. A. Chabner and D. L. Longo (eds.), Philadelphia: J. B. Lippincott
    • Grem, J. L. Fluorinated pyrimidines. In: B. A. Chabner and D. L. Longo (eds.), Cancer Chemotherapy: Principles and Practice, Ed. 2, pp. 149-212. Philadelphia: J. B. Lippincott, 1996.
    • (1996) Cancer Chemotherapy: Principles and Practice, Ed. 2 , pp. 149-212
    • Grem, J.L.1
  • 3
    • 0000513018 scopus 로고    scopus 로고
    • Cancer of the colon
    • V. T. DeVita, Jr., S. Hellman, and S. Rosenberg (eds.), Philadelphia: J. B. Lippincott
    • Cohen, A., Minsky, B., and Schilsky, R. Cancer of the colon. In: V. T. DeVita, Jr., S. Hellman, and S. Rosenberg (eds.), Cancer-Principles and Practice of Oncology, Ed. 5, pp. 1144-1196. Philadelphia: J. B. Lippincott, 1997.
    • (1997) Cancer-Principles and Practice of Oncology, Ed. 5 , pp. 1144-1196
    • Cohen, A.1    Minsky, B.2    Schilsky, R.3
  • 5
    • 0026721532 scopus 로고
    • The advanced colorectal cancer meta-analysis project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • The advanced colorectal cancer meta-analysis project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J. Clin. Oncol., 10: 896-903, 1992.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 896-903
  • 6
    • 0023718558 scopus 로고
    • Interferon effects upon the adenocarcinoma 38 and HL-60 cell lines: Antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites
    • Elias, L., and Crissman, H. A. Interferon effects upon the adenocarcinoma 38 and HL-60 cell lines: antiproliferative responses and synergistic interactions with halogenated pyrimidine antimetabolites. Cancer Res., 48: 4861-4873, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 4861-4873
    • Elias, L.1    Crissman, H.A.2
  • 7
    • 0025052138 scopus 로고
    • Interaction of fluorouracil and interferon in human colon cancer cell lines: Cytotoxic and cytokinetic effects
    • Wadler, S., Wersto, R., Weinberg, V., Wiernik, P. H. Interaction of fluorouracil and Interferon in human colon cancer cell lines: cytotoxic and cytokinetic effects. Cancer Res., 50: 5735-5739, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 5735-5739
    • Wadler, S.1    Wersto, R.2    Weinberg, V.3    Wiernik, P.H.4
  • 8
    • 0026600296 scopus 로고
    • Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cell lines
    • Schwartz, E. L., Hoffman, M., O'Connor, C. J., and Wadler, S. Stimulation of 5-fluorouracil metabolic activation by interferon-α in human colon carcinoma cell lines. Biochem. Biophys. Res. Commun., 182: 1232-1239, 1992.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1232-1239
    • Schwartz, E.L.1    Hoffman, M.2    O'Connor, C.J.3    Wadler, S.4
  • 9
    • 0025043811 scopus 로고
    • Interaction of γ interferon and fluorouracil in the H630 human colon carcinoma cell line
    • Chu, E., Zinn, S., Boarman, D., and Allegra, C. J. Interaction of γ Interferon and fluorouracil in the H630 human colon carcinoma cell line. Cancer Res., 50: 5834-5840, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 5834-5840
    • Chu, E.1    Zinn, S.2    Boarman, D.3    Allegra, C.J.4
  • 10
    • 0021222546 scopus 로고
    • Cytologic activity of interferon-γ and its synergism with 5-fluorouracil
    • Le, J., Yip, Y. K., and Vilcek, J. Cytologic activity of interferon-γ and its synergism with 5-fluorouracil. Int. J. Cancer, 34: 495-500, 1984.
    • (1984) Int. J. Cancer , vol.34 , pp. 495-500
    • Le, J.1    Yip, Y.K.2    Vilcek, J.3
  • 11
    • 0027817576 scopus 로고
    • Locus of the interaction among 5-fluorouracil, leucovorin, and interferon α-2a in colon carcinoma cells
    • Houghton, J. A., Morton, C. L., Adkins, D. A., and Rahman, A. Locus of the interaction among 5-fluorouracil, leucovorin, and interferon α-2a in colon carcinoma cells. Cancer Res., 53: 4243-4250, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 4243-4250
    • Houghton, J.A.1    Morton, C.L.2    Adkins, D.A.3    Rahman, A.4
  • 15
    • 0025945855 scopus 로고
    • Phase II trial of fluorouracil and recombinant interferon α-2a in patients with advanced colorectal carcinoma: An Eastern Cooperative Oncology Group study
    • Wadler, S., Lembersky, B., Atkins, M., Kirkwood, J., and Petrelli, N. Phase II trial of fluorouracil and recombinant interferon α-2a in patients with advanced colorectal carcinoma: an Eastern Cooperative Oncology Group study. J. Clin. Oncol., 9: 1806-1810, 1991.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 1806-1810
    • Wadler, S.1    Lembersky, B.2    Atkins, M.3    Kirkwood, J.4    Petrelli, N.5
  • 16
    • 0026554769 scopus 로고
    • Biochemical modulation of 5-fluorouracil with leucovorin and interferon: Preclinical and clinical investigations
    • Grem, J. L., Chu, E., Boarman, D., Balis, F. M., Murphy, R. F., McAtee, N., and Allegra, C. J. Biochemical modulation of 5-fluorouracil with leucovorin and interferon: preclinical and clinical investigations. Semin. Oncol., 19 (Suppl. 2): 36-44, 1992.
    • (1992) Semin. Oncol. , vol.19 , Issue.SUPPL. 2 , pp. 36-44
    • Grem, J.L.1    Chu, E.2    Boarman, D.3    Balis, F.M.4    Murphy, R.F.5    McAtee, N.6    Allegra, C.J.7
  • 19
    • 0026740918 scopus 로고
    • Granulocyte colony stimulating factor and granulocyte-macrophage colony stimulating factor
    • Lieschke, G. J., and Burgess, A. W. Granulocyte colony stimulating factor and granulocyte-macrophage colony stimulating factor. N. Engl. J. Med., 327: 28-35, 99-106, 1992.
    • (1992) N. Engl. J. Med. , vol.327 , pp. 28-35
    • Lieschke, G.J.1    Burgess, A.W.2
  • 20
    • 0023945042 scopus 로고
    • Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium
    • Gabrilove, J. L., Jakubowski, A., Scher, H., Sternberg, C., Wong, G., Grous, J., Yagoda, A., Fain, K., Moore, M. A., and Clarkson, B. Effect of granulocyte colony-stimulating factor on neutropenia and associated morbidity due to chemotherapy for transitional cell carcinoma of the urothelium. N. Engl. J. Med., 318: 1414-1422, 1988.
    • (1988) N. Engl. J. Med. , vol.318 , pp. 1414-1422
    • Gabrilove, J.L.1    Jakubowski, A.2    Scher, H.3    Sternberg, C.4    Wong, G.5    Grous, J.6    Yagoda, A.7    Fain, K.8    Moore, M.A.9    Clarkson, B.10
  • 21
    • 0028217482 scopus 로고
    • Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma
    • Grem, J. L., McAtee, N., Murphy, R. F., Hamilton, J. M., Balis, F., Steinberg, S., Arbuck, S. G., Setser, A., Jordan, E., Chen, A., Kohler, D. R., Kotite, B., and Allegra, C. J. Phase I and pharmacokinetic study of recombinant human granulocyte-macrophage colony stimulating factor given in combination with fluorouracil plus calcium leucovorin in metastatic gastrointestinal adenocarcinoma. J. Clin. Oncol., 12: 560-568, 1994.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 560-568
    • Grem, J.L.1    McAtee, N.2    Murphy, R.F.3    Hamilton, J.M.4    Balis, F.5    Steinberg, S.6    Arbuck, S.G.7    Setser, A.8    Jordan, E.9    Chen, A.10    Kohler, D.R.11    Kotite, B.12    Allegra, C.J.13
  • 24
    • 0026335113 scopus 로고
    • Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissues
    • Johnston, P. G., Liang, C. M., Henry, S., Chabner, B. A., and Allegra, C. J. Production and characterization of monoclonal antibodies that localize human thymidylate synthase in the cytoplasm of human cells and tissues. Cancer Res., 51: 6668-6676, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6668-6676
    • Johnston, P.G.1    Liang, C.M.2    Henry, S.3    Chabner, B.A.4    Allegra, C.J.5
  • 25
    • 0019492861 scopus 로고
    • A comparative study of the peroxidase-antiperoxidase method and an avidin biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies
    • Hsu, S. M., Raine, L., and Fanger, H. A comparative study of the peroxidase-antiperoxidase method and an avidin biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am. J. Clin. Pathol., 75: 734-738, 1981.
    • (1981) Am. J. Clin. Pathol. , vol.75 , pp. 734-738
    • Hsu, S.M.1    Raine, L.2    Fanger, H.3
  • 26
  • 28
    • 33845382806 scopus 로고
    • Non-parametric estimation from incomplete observations
    • Kaplan, E., and Meier, P. Non-parametric estimation from incomplete observations. J. Am. Stat. Assoc., 53: 457-481, 1958.
    • (1958) J. Am. Stat. Assoc. , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 29
    • 0013886333 scopus 로고
    • Evaluation of survival data and two new rank order statistics arising on its consideration
    • Mantel, N. Evaluation of survival data and two new rank order statistics arising on its consideration. Cancer Chemother. Rep., 50: 163-170, 1966.
    • (1966) Cancer Chemother. Rep. , vol.50 , pp. 163-170
    • Mantel, N.1
  • 30
    • 0031879654 scopus 로고    scopus 로고
    • Clinical trial of weekly intensive therapy with 5-fluorouracil on two different schedules combined with interferon α-2a and filgrastim in patients with advanced solid tumors: Eastern Cooperative Oncology Group Study P-Z991
    • Wadler, S., Atkins, M., Karp, D., Neuberg, D., Haynes, H., and Dutcher, J. P. Clinical trial of weekly intensive therapy with 5-fluorouracil on two different schedules combined with interferon α-2a and filgrastim in patients with advanced solid tumors: Eastern Cooperative Oncology Group Study P-Z991. Cancer J. Sci. Am., 4: 261-268, 1998.
    • (1998) Cancer J. Sci. Am. , vol.4 , pp. 261-268
    • Wadler, S.1    Atkins, M.2    Karp, D.3    Neuberg, D.4    Haynes, H.5    Dutcher, J.P.6
  • 31
    • 0004521702 scopus 로고
    • Interferon effects upon fluorouracil metabolism by HL-60 cells
    • Elias, L., and Sandoval, J. M. Interferon effects upon fluorouracil metabolism by HL-60 cells. Biochem. Biophys. Res. Commun., 182: 1232-1239, 1992.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1232-1239
    • Elias, L.1    Sandoval, J.M.2
  • 34
    • 0028956096 scopus 로고
    • Phase III randomized study of two fluorouracil combinations with either interferon α-2a or leucovorin for advanced colorectal cancer
    • Corfu-A Study Group. Phase III randomized study of two fluorouracil combinations with either interferon α-2a or leucovorin for advanced colorectal cancer. J. Clin. Oncol., 13: 921-928, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 921-928
  • 35
    • 0029003849 scopus 로고
    • Interferon-α does not improve the antineoplastic activity of high-dose infusional 5-fluorouracil plus folinic acid in advanced colorectal cancer
    • Kohne, C. H., Wilke, H., Hecker, H. Schoffski, P., Kaufer, C., Rauschecker, H., Andreesen, R., Ohl, U., Lange, H. J., and Klaassen, U. Interferon-α does not improve the antineoplastic activity of high-dose infusional 5-fluorouracil plus folinic acid in advanced colorectal cancer. Ann. Oncol., 6: 461-466, 1995.
    • (1995) Ann. Oncol. , vol.6 , pp. 461-466
    • Kohne, C.H.1    Wilke, H.2    Hecker, H.3    Schoffski, P.4    Kaufer, C.5    Rauschecker, H.6    Andreesen, R.7    Ohl, U.8    Lange, H.J.9    Klaassen, U.10
  • 39
    • 0028019880 scopus 로고
    • Thymidylate synthase inhibition after administration of fluorouracil with and without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
    • Peters, G. J., Van der Wilt, C. L., Van Groeningen, C. J., Smid, K., Meijer, S., and Pinedo, H. M. Thymidylate synthase inhibition after administration of fluorouracil with and without leucovorin in colon cancer patients: implications for treatment with fluorouracil. J. Clin. Oncol., 12: 2035-2042, 1994.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2035-2042
    • Peters, G.J.1    Van Der Wilt, C.L.2    Van Groeningen, C.J.3    Smid, K.4    Meijer, S.5    Pinedo, H.M.6
  • 41
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Leichman, C. G., Lenz, H. J., Leichman, L., Danenberg, K., Baranda, J., Groshen, S., Boswell, W., Metzger, R., Tan, M., and Danenberg, P. V. Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J. Clin. Oncol., 15: 3223-3229, 1997.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3    Danenberg, K.4    Baranda, J.5    Groshen, S.6    Boswell, W.7    Metzger, R.8    Tan, M.9    Danenberg, P.V.10
  • 42
    • 0031053520 scopus 로고    scopus 로고
    • Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy
    • Findlay, M. P. N., Cunningham, D., Morgan, G., Clinton, S., Hardcastle, A., and Aherne, G. W. Lack of correlation between thymidylate synthase levels in primary colorectal tumours and subsequent response to chemotherapy. Br. J. Cancer, 75: 903-909, 1997.
    • (1997) Br. J. Cancer , vol.75 , pp. 903-909
    • Findlay, M.P.N.1    Cunningham, D.2    Morgan, G.3    Clinton, S.4    Hardcastle, A.5    Aherne, G.W.6
  • 43
    • 0344624286 scopus 로고    scopus 로고
    • Thymidylate synthase expression as a predictor for response to 5-fluorouracil based therapy and survival for patients with resected colon or advanced colorectal cancer. An ECOG study
    • Benson, A. B., III, Catalano, P. J., Rao, S., Haller, D. G., O'Dwyer, P. J., Allegra, C. J., and Johnston, P. G. Thymidylate synthase expression as a predictor for response to 5-fluorouracil based therapy and survival for patients with resected colon or advanced colorectal cancer. An ECOG study. Proc. Am. Soc. Clin. Oncol., 16: 917, 1997.
    • (1997) Proc. Am. Soc. Clin. Oncol. , vol.16 , pp. 917
    • Benson A.B. III1    Catalano, P.J.2    Rao, S.3    Haller, D.G.4    O'Dwyer, P.J.5    Allegra, C.J.6    Johnston, P.G.7
  • 44
    • 0001849087 scopus 로고
    • Thymidylate synthase protein expression. Association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma
    • Alexander, H. R., Grem, J. L., Hamilton, J. M., Pass, H. I., Hong, M., Fraker, D. L., Steinberg, S. M., McAtee, N., Allegra, C. J., and Johnston, P. G. Thymidylate synthase protein expression. Association with response to neoadjuvant chemotherapy and resection for locally advanced gastric and gastroesophageal adenocarcinoma. Cancer J. Sci. Am., 1: 49-54, 1995.
    • (1995) Cancer J. Sci. Am. , vol.1 , pp. 49-54
    • Alexander, H.R.1    Grem, J.L.2    Hamilton, J.M.3    Pass, H.I.4    Hong, M.5    Fraker, D.L.6    Steinberg, S.M.7    McAtee, N.8    Allegra, C.J.9    Johnston, P.G.10
  • 45
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
    • Johnston, P. G., Fisher, E. R., Rockette, H. E., Fisher, B., Wolmark, N., Drake, J. C., Chabner, B. A., and Allegra, C. J. The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J. Clin. Oncol., 12: 2640-2647, 1994.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.R.2    Rockette, H.E.3    Fisher, B.4    Wolmark, N.5    Drake, J.C.6    Chabner, B.A.7    Allegra, C.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.