Synthesis and binding properties of photoactivable biotin-conjugated verapamil derivatives for the study of P-170 glycoprotein

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 9, 1999, Pages 1873-1880

  Teodori, Elisabetta ^a   Ettori, Dominique ^b   Garnier Suillerot, Arlette ^b   Gualtieri, Fulvio ^a   Manetti, Dina ^a   Novella Romanelli, Maria ^a   Scapecchi, Serena ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITÉ PARIS 13   (France)

Author keywords

Biotin labeled compounds; Multidrug resistance; P glycoprotein; Photoaffinity labeling; Verapamil analogues

Indexed keywords

2 (3,4 DIMETHOXYPHENYL) 2 [3 (1 BIOTINYL)PROPYL ESTER] 5 [2 (2 AZIDOPHENETHYL)METHYLAMINO]VALERONITRILE; 2 (3,4 DIMETHOXYPHENYL) 2 [3 (1 BIOTINYL)PROPYL ESTER] 5 [2 (4 AZIDOPHENETHYL)METHYLAMINO]VALERONITRILE; AVIDIN; BIOTIN; EDP 137; EDP 141; GLYCOPROTEIN P 170; UNCLASSIFIED DRUG; VERAPAMIL DERIVATIVE;

ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; PROTEIN ANALYSIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

BIOTIN; HUMANS; K562 CELLS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR PROBES; P-GLYCOPROTEIN; PHOTOCHEMISTRY; SPECTROPHOTOMETRY, INFRARED; VERAPAMIL;

EID: 0032882920     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00104-2     Document Type: Article

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