Iron metabolism in eukaryotes: Mars and Venus at it again

Science

Volumn 271, Issue 5255, 1996, Pages 1510-1512

  Kaplan, Jerry ^a   O'Halloran, Thomas V ^b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTA;

CARRIER PROTEIN; CERULOPLASMIN; COPPER; FERRIC ION; FERROUS ION; FET3 PROTEIN, S CEREVISIAE; FTR1 PROTEIN, S CEREVISIAE; IRON; OXIDOREDUCTASE; SACCHAROMYCES CEREVISIAE PROTEIN;

ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; NOTE; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CERULOPLASMIN; COPPER; FERRIC COMPOUNDS; FERROUS COMPOUNDS; IRON; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0030584404     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.271.5255.1510     Document Type: Article

References (25)

1. I. Zaitseva et al, J Biol, Inorg. Chem 1, 15 (1996)
2. R. Stearman, D. S. Yuan, Y Yamaguchi-Iwai, R. D. Klausner, A. Dancis, Science 271, 1552 (1996).
3. D. R. Dix, J T. Bridgham, M. A. Broderius, C. A. Byersdorfer, D J Eide, J. Biol Chem 269, 26092 (1994).
4. C. Askwith et al., Cell 76, 403 (1994)
5. D de Silva, C. Askwith, D. J. Eide, J. Kaplan, J. Biol Chem 270, 1098 (1995)
6. A Dancis et al, Cell 76, 393 (1994).
7. M Kammler, C Schoin, D. Hantke, J. Bacteriol. 175, 6212 (1993).
8. G R Lee, S. Nacht, J N Lukens, G E Cartwright, J. Clin Invest 47, 2058 (1968)
9. Z. L Harns et al., Proc Natl Acad Sci USA 92, 2539 (1995).
10. K Yoshida et al, Nature Genet 9, 267 (1995)
11. S Osaki, D. A Johnson, E Frieden, J. Biol. Chem. 241, 2746 (1966)
12. E Saenko, A. Yaropolov, E Harris, J. Trace Elements Exp. Med 7, 69 (1994).
13. Z Harris, H Morita, J Gitlin, in Multicopper Oxidases, A Messerschmidt, Ed. (World Scientific, Singapore, in press)
14. J Bryson et al., Bioinorganic Chemistry of Copper, K D Karlin and Z Tyeklar, Eds (Chapman and Hall, New York, 1993), pp. 101-109
15. G Munson, D Huffman, T. V. O'Halloran, unpublished results.
16. C Collyer, J. Guss, Y Sugimura, F Yoshizaki, H. Freeman, J Mol Biol. 211, 617 (1990).
17. A Messerschmidt and R Huber, Eur. J. Biochem. 187, 341 (1990).
18. A Messerschmidt et al., J. Mol Biol 224, 179 (1992)
19. J W Godden et al, Science 253, 438 (1991).
20. F F. Fenderson et al., Biochemistry 30, 7180 (1991)
21. Y. Pan, T DeFay, J. Gitschier, F. Cohen, Nature Struct Biol 2 (no. 9), 740 (1995)
22. R. Langen et al , Science 268, 1733 (1995).
23. P Lindley, personal communication.
24. Charge distributions were calculated by P. Lindley and co-workers with the program GRASP incorporating the Del Phi algorithm [A. Nicholls and B Honig, J. Comput. Chem. 12, 435 (1991)]
25. We thank P Lindley (E-mail: pfhndley@ daresburyacuk) and G. Card for providing preliminary results and Figs 2 and 3.