-
1
-
-
0026079136
-
Bioactivation of xenobiotics by formation of toxic glutathione conjugates
-
Koob M., Dekant W. Bioactivation of xenobiotics by formation of toxic glutathione conjugates. Chem Biol Interact. 77:1991;107-136.
-
(1991)
Chem Biol Interact
, vol.77
, pp. 107-136
-
-
Koob, M.1
Dekant, W.2
-
2
-
-
0028190695
-
Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: Cysteine conjugate β-lyase pathway
-
Dekant W., Vamvakas S., Anders M.W. Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates Cysteine conjugate β-lyase pathway . Adv Pharmacol. 27:1994;115-162.
-
(1994)
Adv Pharmacol
, vol.27
, pp. 115-162
-
-
Dekant, W.1
Vamvakas, S.2
Anders, M.W.3
-
3
-
-
0345135505
-
Enzymes involved in processing glutathione conjugates
-
I.G. Sipes, C.A. McQueen, A.J. Gandolfi, Guengerich F.P. Oxford: Elsevier
-
Cooper A.J.L., Tate S.S. Enzymes involved in processing glutathione conjugates. Sipes I.G., McQueen C.A., Gandolfi A.J., Guengerich F.P. Comprehensive Toxicology. Vol. 3:1998;329-363 Elsevier, Oxford.
-
(1998)
Comprehensive Toxicology
, vol.3
, pp. 329-363
-
-
Cooper, A.J.L.1
Tate, S.S.2
-
4
-
-
0028315145
-
Enzymology of cysteine S-conjugate β-lyases
-
Cooper A.J.L. Enzymology of cysteine S-conjugate β-lyases. Adv Pharmacol. 27:1994;71-113.
-
(1994)
Adv Pharmacol
, vol.27
, pp. 71-113
-
-
Cooper, A.J.L.1
-
5
-
-
0021236594
-
The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity
-
Nash J.A., King L.J., Lock E.A., Green T. The metabolism and disposition of hexachloro-1:3-butadiene in the rat and its relevance to nephrotoxicity. Toxicol Appl Pharmacol. 73:1984;124-137.
-
(1984)
Toxicol Appl Pharmacol
, vol.73
, pp. 124-137
-
-
Nash, J.A.1
King, L.J.2
Lock, E.A.3
Green, T.4
-
6
-
-
0025327018
-
The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogense activities
-
Lock E.A., Schnellmann R.G. The effect of haloalkene cysteine conjugates on rat renal glutathione reductase and lipoyl dehydrogense activities. Toxicol Appl Pharmacol. 104:1990;180-190.
-
(1990)
Toxicol Appl Pharmacol
, vol.104
, pp. 180-190
-
-
Lock, E.A.1
Schnellmann, R.G.2
-
7
-
-
0026287447
-
Pentachlorobutadienyl-L-cysteine (PLBC) toxicity: The importance of mitochondrial dysfunction
-
Groves C.E., Schnellmann R.G., Sokol P.P., Steffens T.G., Lock A.E. Pentachlorobutadienyl-L-cysteine (PLBC) toxicity The importance of mitochondrial dysfunction . J Biochem Toxicol. 6:1991;253-260.
-
(1991)
J Biochem Toxicol
, vol.6
, pp. 253-260
-
-
Groves, C.E.1
Schnellmann, R.G.2
Sokol, P.P.3
Steffens, T.G.4
Lock, A.E.5
-
8
-
-
0031041496
-
Intranephron distribution of cysteine-S-conjugate β-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats
-
Kim H.S., Cha S.H., Abraham D.G., Cooper A.J.L., Endou H. Intranephron distribution of cysteine-S-conjugate β-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats. Arch Toxicol. 71:1997;131-141.
-
(1997)
Arch Toxicol
, vol.71
, pp. 131-141
-
-
Kim, H.S.1
Cha, S.H.2
Abraham, D.G.3
Cooper, A.J.L.4
Endou, H.5
-
9
-
-
0022891407
-
The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells
-
Jones T.W., Wallin A., Thor H., Gerdes R.G., Ormstad K., Orrenius S. The mechanism of pentachlorobutadienyl-glutathione nephrotoxicity studied with isolated rat renal epithelial cells. Arch Biochem Biophys. 251:1986;504-513.
-
(1986)
Arch Biochem Biophys
, vol.251
, pp. 504-513
-
-
Jones, T.W.1
Wallin, A.2
Thor, H.3
Gerdes, R.G.4
Ormstad, K.5
Orrenius, S.6
-
10
-
-
0002030669
-
Bioactivation and cytotoxicity of nephrotoxic amino acid and glutathione S-conjugates
-
Lash L.H., Anders M.W. Bioactivation and cytotoxicity of nephrotoxic amino acid and glutathione S-conjugates. Comments Toxicol. 1:1986;87-107.
-
(1986)
Comments Toxicol
, vol.1
, pp. 87-107
-
-
Lash, L.H.1
Anders, M.W.2
-
11
-
-
0023449792
-
Toxicity of S-pentachlorobutadienyl-L-cysteine studied with isolated rat renal cortical mitochondria
-
Wallin A., Jones T.W., Vercesi A.E., Cotgreave I., Ormstad K., Orrenius S. Toxicity of S-pentachlorobutadienyl-L-cysteine studied with isolated rat renal cortical mitochondria. Arch Biochem Biophys. 258:1987;365-372.
-
(1987)
Arch Biochem Biophys
, vol.258
, pp. 365-372
-
-
Wallin, A.1
Jones, T.W.2
Vercesi, A.E.3
Cotgreave, I.4
Ormstad, K.5
Orrenius, S.6
-
12
-
-
0024454859
-
Pentachlorobutadienyl-L-cysteine uncouples oxidative phosphorylation by dissipating the proton gradient
-
Schnellmann R.G., Cross T.J., Lock E.A. Pentachlorobutadienyl-L-cysteine uncouples oxidative phosphorylation by dissipating the proton gradient. Toxicol Appl Pharmacol. 100:1989;498-505.
-
(1989)
Toxicol Appl Pharmacol
, vol.100
, pp. 498-505
-
-
Schnellmann, R.G.1
Cross, T.J.2
Lock, E.A.3
-
13
-
-
0025092615
-
Perturbations of intracellular calcium distribution in kidney cells by nephrotoxic haloalkenyl cysteine S-conjugates
-
Vamvakas S., Sharma V.K., Shen S.S., Anders M.W. Perturbations of intracellular calcium distribution in kidney cells by nephrotoxic haloalkenyl cysteine S-conjugates. Mol Pharmacol. 38:1990;455-461.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 455-461
-
-
Vamvakas, S.1
Sharma, V.K.2
Shen, S.S.3
Anders, M.W.4
-
15
-
-
0015120455
-
2-Oxoacid dehydrogenases of rat liver mitochondria as the site of action of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-3-mercaptopropionic acid
-
Stonard M.D., Parker V.H. 2-Oxoacid dehydrogenases of rat liver mitochondria as the site of action of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-3-mercaptopropionic acid. Biochem Pharmacol. 20:1971;2417-2427.
-
(1971)
Biochem Pharmacol
, vol.20
, pp. 2417-2427
-
-
Stonard, M.D.1
Parker, V.H.2
-
16
-
-
0025261923
-
Cysteine conjugate toxicity, metabolism and binding to macromolecules in isolated rat kidney mitochondria
-
Hayden P.J., Stevens J.L. Cysteine conjugate toxicity, metabolism and binding to macromolecules in isolated rat kidney mitochondria. Mol Pharmacol. 37:1990;468-476.
-
(1990)
Mol Pharmacol
, vol.37
, pp. 468-476
-
-
Hayden, P.J.1
Stevens, J.L.2
-
17
-
-
0027491608
-
Mitochondrial HSP 60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2,2-tetrafluororethyl)-L-cysteine-induced toxicity
-
Bruschi S.A., West K.A., Crabb J.W., Gupta R.S., Stevens J.L. Mitochondrial HSP 60 (P1 protein) and a HSP70-like protein (mortalin) are major targets for modification during S-(1,1,2,2,2-tetrafluororethyl)-L-cysteine-induced toxicity. J Biol Chem. 268:1993;23157-23161.
-
(1993)
J Biol Chem
, vol.268
, pp. 23157-23161
-
-
Bruschi, S.A.1
West, K.A.2
Crabb, J.W.3
Gupta, R.S.4
Stevens, J.L.5
-
18
-
-
0032506133
-
Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death
-
Bruschi S.A., Lindsay J.G., Crabb J.W. Mitochondrial stress protein recognition of inactivated dehydrogenases during mammalian cell death. Proc Natl Acad Sci USA. 95:1998;13413-13418.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13413-13418
-
-
Bruschi, S.A.1
Lindsay, J.G.2
Crabb, J.W.3
-
19
-
-
0027497132
-
High activities of glutamine transaminase K (dichlorovinylcysteine β-lyase) and ω-amidase in the choroid plexus of rat brain
-
Cooper A.J.L., Abraham D.G., Gelbard A.S., Lai J.C.K., Petito C.K. High activities of glutamine transaminase K (dichlorovinylcysteine β-lyase) and ω-amidase in the choroid plexus of rat brain. J Neurochem. 61:1993;1731-1741.
-
(1993)
J Neurochem
, vol.61
, pp. 1731-1741
-
-
Cooper, A.J.L.1
Abraham, D.G.2
Gelbard, A.S.3
Lai, J.C.K.4
Petito, C.K.5
-
21
-
-
0021713999
-
Formation of dichloroacetylene from trichloroethylene in the presence of alkaline material - Possible cause of intoxication after abundant use of trichloroethylene
-
Greim H., Wolff T., Höffler M., Lahaniatis E. Formation of dichloroacetylene from trichloroethylene in the presence of alkaline material - Possible cause of intoxication after abundant use of trichloroethylene. Arch Toxicol. 56:1984;74-77.
-
(1984)
Arch Toxicol
, vol.56
, pp. 74-77
-
-
Greim, H.1
Wolff, T.2
Höffler, M.3
Lahaniatis, E.4
-
22
-
-
0014180936
-
Polyneuritis cranialis associated with industrial trichloroethylene poisoning
-
Buxton P.H., Hayward M. Polyneuritis cranialis associated with industrial trichloroethylene poisoning. J Neurol Neurosurg Psychiatry. 30:1967;511-518.
-
(1967)
J Neurol Neurosurg Psychiatry
, vol.30
, pp. 511-518
-
-
Buxton, P.H.1
Hayward, M.2
-
23
-
-
0017122070
-
Inhibition of acetylcholine synthesis and of carbohydrate utilization by maple-syrup-urine disease metabolites
-
Gibson G.E., Blass J.P. Inhibition of acetylcholine synthesis and of carbohydrate utilization by maple-syrup-urine disease metabolites. J Neurochem. 26:1976;1073-1078.
-
(1976)
J Neurochem
, vol.26
, pp. 1073-1078
-
-
Gibson, G.E.1
Blass, J.P.2
-
24
-
-
0023732664
-
Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease
-
Gibson G.E., Sheu K.-F.R., Blass J.P., Baker A., Carlson K.C., Harding B., Perrino P. Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease. Arch Neurol. 45:1988;836-840.
-
(1988)
Arch Neurol
, vol.45
, pp. 836-840
-
-
Gibson, G.E.1
Sheu, K.-F.R.2
Blass, J.P.3
Baker, A.4
Carlson, K.C.5
Harding, B.6
Perrino, P.7
-
25
-
-
0031754275
-
α-Ketoglutarate dehydrogenase in Alzheimer brains bearing the APP670/671 mutation
-
Gibson G.E., Zhang H., Sheu K.-F.R., Bogdanovich N., Lindsay J.G., Lannfelt L., Vestling M., Cowburn R.F. α-Ketoglutarate dehydrogenase in Alzheimer brains bearing the APP670/671 mutation. Ann Neurol. 44:1998;676-681.
-
(1998)
Ann Neurol
, vol.44
, pp. 676-681
-
-
Gibson, G.E.1
Zhang, H.2
Sheu, K.-F.R.3
Bogdanovich, N.4
Lindsay, J.G.5
Lannfelt, L.6
Vestling, M.7
Cowburn, R.F.8
-
26
-
-
0028176592
-
An immunohistochemical study on α-ketoglutarate dehydrogenase complex in Parkinson's disease
-
Mizuno Y., Matsuda S., Yoshino H., Mori H., Hattori N., Ikebe S.I. An immunohistochemical study on α-ketoglutarate dehydrogenase complex in Parkinson's disease. Ann Neurol. 35:1994;204-210.
-
(1994)
Ann Neurol
, vol.35
, pp. 204-210
-
-
Mizuno, Y.1
Matsuda, S.2
Yoshino, H.3
Mori, H.4
Hattori, N.5
Ikebe, S.I.6
-
27
-
-
0029884010
-
Brain protein and α-ketoglutarate dehydrogenase complex activity in Alzheimer's disease
-
Mastrogiacomo F., Lindsay J.G., Bettendorff L., Rice J., Kish S.J. Brain protein and α-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. Ann Neurol. 39:1996;592-598.
-
(1996)
Ann Neurol
, vol.39
, pp. 592-598
-
-
Mastrogiacomo, F.1
Lindsay, J.G.2
Bettendorff, L.3
Rice, J.4
Kish, S.J.5
-
28
-
-
0019074779
-
Purification of 2-oxoacid dehydrogenase multienzyme complexes from ox heart by a new method
-
Stanley C.J., Perham R.N. Purification of 2-oxoacid dehydrogenase multienzyme complexes from ox heart by a new method. Biochem J. 191:1980;147-154.
-
(1980)
Biochem J
, vol.191
, pp. 147-154
-
-
Stanley, C.J.1
Perham, R.N.2
-
29
-
-
0027133652
-
Thioredoxin reduction dependent on α-ketoacid oxidation by α-ketoacid dehydrogenase complexes
-
Bunik V., Follmann H. Thioredoxin reduction dependent on α-ketoacid oxidation by α-ketoacid dehydrogenase complexes. FEBS Lett. 336:1993;197-200.
-
(1993)
FEBS Lett
, vol.336
, pp. 197-200
-
-
Bunik, V.1
Follmann, H.2
-
30
-
-
0018145510
-
Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between l-phenylalanine and α-keto-γ-methiolbutyrate
-
Cooper A.J.L. Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between l-phenylalanine and α-keto-γ-methiolbutyrate. Anal Biochem. 89:1978;451-460.
-
(1978)
Anal Biochem
, vol.89
, pp. 451-460
-
-
Cooper, A.J.L.1
-
31
-
-
0029164474
-
The role of signal transduction systems in mediating cell density dependent changes in tyrosine hydroxylase gene expression
-
Kim K.S., Huang H.M., Zhang H., Wagner J., Joh T., Gibson G.E. The role of signal transduction systems in mediating cell density dependent changes in tyrosine hydroxylase gene expression. Brain Res Mol Brain Res. 33:1995;254-260.
-
(1995)
Brain Res Mol Brain Res
, vol.33
, pp. 254-260
-
-
Kim, K.S.1
Huang, H.M.2
Zhang, H.3
Wagner, J.4
Joh, T.5
Gibson, G.E.6
-
32
-
-
0023264679
-
Separate microassays for aspartate aminotransferase isoenzymes
-
Parli J.D., Godfrey D.A., Ross C.D. Separate microassays for aspartate aminotransferase isoenzymes. Biochim Biophys Acta. 925:1987;175-184.
-
(1987)
Biochim Biophys Acta
, vol.925
, pp. 175-184
-
-
Parli, J.D.1
Godfrey, D.A.2
Ross, C.D.3
-
33
-
-
0019945166
-
Studies on the pyruvate dehydrogenase complex in brain with arylamine acetyltransferase-coupled assay
-
Ksiezak-Reding H., Blass J.P., Gibson G.E. Studies on the pyruvate dehydrogenase complex in brain with arylamine acetyltransferase-coupled assay. J Neurochem. 38:1982;1627-1636.
-
(1982)
J Neurochem
, vol.38
, pp. 1627-1636
-
-
Ksiezak-Reding, H.1
Blass, J.P.2
Gibson, G.E.3
-
34
-
-
0019420189
-
Pyruvate dehydrogenase complex in normal and deficient fibroblasts
-
Sheu K.-F.R., Hu C.W.C., Utter M.F. Pyruvate dehydrogenase complex in normal and deficient fibroblasts. J Clin Invest. 67:1981;1463-1471.
-
(1981)
J Clin Invest
, vol.67
, pp. 1463-1471
-
-
Sheu, K.-F.R.1
Hu, C.W.C.2
Utter, M.F.3
-
35
-
-
0020494539
-
A novel reaction of the coenzyme of glutamate decarboxylase with L-serine-O-sulfate
-
Likos J.J., Ueno H., Feldhaus R.W., Metzler D.E. A novel reaction of the coenzyme of glutamate decarboxylase with L-serine-O-sulfate. Biochemistry. 21:1982;4377-4386.
-
(1982)
Biochemistry
, vol.21
, pp. 4377-4386
-
-
Likos, J.J.1
Ueno, H.2
Feldhaus, R.W.3
Metzler, D.E.4
-
36
-
-
0025685477
-
The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells
-
Chen Q., Jones T.W., Brown P.C., Stevens J.L. The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. J Biol Chem. 265:1990;21603-21611.
-
(1990)
J Biol Chem
, vol.265
, pp. 21603-21611
-
-
Chen, Q.1
Jones, T.W.2
Brown, P.C.3
Stevens, J.L.4
-
38
-
-
0029801976
-
Inactivation of brain and kidney aspartate aminotransferases by S-(1,2-dichlorovinyl)-L-cysteine and by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine
-
Kato Y., Asano Y., Cooper A.J.L. Inactivation of brain and kidney aspartate aminotransferases by S-(1,2-dichlorovinyl)-L-cysteine and by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine. Dev Neurosci. 18:1996;505-514.
-
(1996)
Dev Neurosci
, vol.18
, pp. 505-514
-
-
Kato, Y.1
Asano, Y.2
Cooper, A.J.L.3
-
39
-
-
0020494540
-
Chemistry of the inactivation of cytosolic aspartate aminotransferase by serine O-sulfate
-
Ueno H., Likos J.J., Metzler D.E. Chemistry of the inactivation of cytosolic aspartate aminotransferase by serine O-sulfate. Biochemistry. 21:1982;4387-4393.
-
(1982)
Biochemistry
, vol.21
, pp. 4387-4393
-
-
Ueno, H.1
Likos, J.J.2
Metzler, D.E.3
-
40
-
-
0029586365
-
The interaction between lipoamide dehydrogenase and the peripheral-component-binding domain from the Azotobacter vinelandii pyruvate dehydrogenase complex
-
Westphal A.H., Fabisz-Kijowska A., Kester H., Obels P.P., De Kok A. The interaction between lipoamide dehydrogenase and the peripheral-component-binding domain from the Azotobacter vinelandii pyruvate dehydrogenase complex. Eur J Biochem. 234:1995;861-870.
-
(1995)
Eur J Biochem
, vol.234
, pp. 861-870
-
-
Westphal, A.H.1
Fabisz-Kijowska, A.2
Kester, H.3
Obels, P.P.4
De Kok, A.5
-
41
-
-
0032508722
-
Subunit interactions in the mammalian α-ketoglutarate dehydrogenase complex. Evidence for direct association of the α-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components
-
McCartney R.G., Rice J.E., Sanderson S.J., Bunik V., Lindsay H., Lindsay J.G. Subunit interactions in the mammalian α-ketoglutarate dehydrogenase complex. Evidence for direct association of the α-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components. J Biol Chem. 237:1998;24159-24164.
-
(1998)
J Biol Chem
, vol.237
, pp. 24159-24164
-
-
McCartney, R.G.1
Rice, J.E.2
Sanderson, S.J.3
Bunik, V.4
Lindsay, H.5
Lindsay, J.G.6
-
42
-
-
0021062309
-
Use of β-methylene-D,L-aspartate to assess the role of aspartate aminotransferase in cerebral oxidative metabolism
-
Fitzpatrick S.M., Cooper A.J.L., Duffy T.E. Use of β-methylene-D,L-aspartate to assess the role of aspartate aminotransferase in cerebral oxidative metabolism. J Neurochem. 41:1983;1370-1383.
-
(1983)
J Neurochem
, vol.41
, pp. 1370-1383
-
-
Fitzpatrick, S.M.1
Cooper, A.J.L.2
Duffy, T.E.3
-
43
-
-
0032506040
-
Selective inactivation of α-ketoglutarate dehydrogenase and pyruvate dehydrogenase: Reaction of lipoic acid with 4-hydroxy-2-nonenal
-
Humphries K.M., Szweda L.I. Selective inactivation of α-ketoglutarate dehydrogenase and pyruvate dehydrogenase Reaction of lipoic acid with 4-hydroxy-2-nonenal . Biochemistry. 37:1998;15835-15841.
-
(1998)
Biochemistry
, vol.37
, pp. 15835-15841
-
-
Humphries, K.M.1
Szweda, L.I.2
-
44
-
-
0033048258
-
Metabolic impairment induces oxidative stress, compromises inflammatory responses and inactivates a key mitochondrial enzyme in microglia
-
Park L.C.H., Zhang H., Sheu K.-F.R., Calingasan N.Y., Kristal B.S., Lindsay J.G., Gibson G.E. Metabolic impairment induces oxidative stress, compromises inflammatory responses and inactivates a key mitochondrial enzyme in microglia. J Neurochem. 72:1999;1948-1958.
-
(1999)
J Neurochem
, vol.72
, pp. 1948-1958
-
-
Park, L.C.H.1
Zhang, H.2
Sheu, K.-F.R.3
Calingasan, N.Y.4
Kristal, B.S.5
Lindsay, J.G.6
Gibson, G.E.7
-
45
-
-
0027332651
-
Brain alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease
-
Mastrogiacomo F., Bergeron C., Kish S.J. Brain alpha-ketoglutarate dehydrogenase complex activity in Alzheimer's disease. J Neurochem. 61:1993;2007-2014.
-
(1993)
J Neurochem
, vol.61
, pp. 2007-2014
-
-
Mastrogiacomo, F.1
Bergeron, C.2
Kish, S.J.3
-
46
-
-
0027131501
-
Thiamine-dependent enzyme changes in the brains of alcoholics: Relationship to the Wernicke-Korsakoff syndrome
-
Butterworth R.F., Kril J.J., Harper C.G. Thiamine-dependent enzyme changes in the brains of alcoholics Relationship to the Wernicke-Korsakoff syndrome . Alcohol Clin Exp Res. 71:1993;1084-1088.
-
(1993)
Alcohol Clin Exp Res
, vol.71
, pp. 1084-1088
-
-
Butterworth, R.F.1
Kril, J.J.2
Harper, C.G.3
|