Regulation of cell cycle transcription factor Swi4 through auto- inhibition of DNA binding

Molecular and Cellular Biology

Volumn 19, Issue 10, 1999, Pages 6729-6741

  Baetz, Kristin ^a   Andrews, Brenda ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; DNA BINDING PROTEIN; PROTEIN SWI4; PROTEIN SWI6; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA BINDING; INHIBITION KINETICS; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; STRAIN DIFFERENCE; TRANSCRIPTION REGULATION;

INSECTA; SACCHAROMYCES CEREVISIAE; UNIDENTIFIED BACULOVIRUS;

EID: 0032875465     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.10.6729     Document Type: Article

References (52)

1. Amon, A., M. Tyers, B. Futcher, and K. Nasmyth. 1993. Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins. Cell 74:993-1007.
2. Andrews, B. J., and I. Herskowitz. 1989. Identification of a DNA binding factor involved in cell-cycle control of the yeast HO gene. Cell 57:21-29.
3. Andrews, B. J., and I. Herskowitz. 1989. The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription. Nature 342:830-833.
4. Andrews, B. J., and L. A. Moore. 1992. Interaction of the yeast Swi4 and Swi6 cell cycle regulatory proteins in vitro. Proc. Natl. Acad. Sci. USA 89:11852-11856.
5. Bassuk, A. G., and J. M. Leiden. 1997. The role of Ets transcription factors in the development and function of the mammalian immune system. Adv. Immunol. 64:65-104.
6. Bork, P. 1993. Hundreds of ankyrin-like repeats in functionally diverse proteins; mobile modules that cross phyla horizontally? Proteins 17:363-374.
7. Breeden, L., and K. Nasmyth. 1985. Regulation of HO. Cold Spring Harbor Symp. Quant. Biol. 50:643-650.
8. Breeden, L. L. (ed.). 1996. Start-specific transcription in yeast. Curr. Top. Microbiol. Immunol. 208:95-127.
9. Breeden, L. L., and K. Nasmyth. 1987. Cell cycle control of the yeast HO gene: cis-and trans-acting regulators. Cell 48:389-397.
10. Brown, T., and S. McKnight. 1992. Specificities of protein-protein and protein-DNA interaction of GABPα and two newly defined Ets-related proteins. Genes Dev. 6:2502-2512.
11. Cosma, M. P., T. Tanaka, and K. Nasmyth. 1999. Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle-and developmentally regulated promoter. Cell 97:299-311.
12. Davey, M. J., and B. E. Funnell. 1994. The P1 plasmid partition protein ParA: a role for ATP in site specific DNA binding. J. Biol. Chem. 269:29908-29913.
13. de la Brousse, F., E. Birkenmeier, D. King, B. Rowe, and S. McKnight. 1994. Molecular and genetic characterization of GABPβ. Genes Dev. 8:1853-1865.
14. Dirick, L., T. Bohm, and K. Nasmyth. 1995. Roles and regulation of Cln/ Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. EMBO J. 14:4803-4813.
15. Donoviel, M. Personal communication.
16. Espinoza, F. H., J. Ogas, I. Herskowitz, and D. O. Morgan. 1994. Cell cycle control by a complex of the cyclin HCS26(PCL1) and the kinase PHO85. Science 266:1388-1391.
17. Ewaskow, S. P., J. M. Sidorova, J. Hendle, J. C. Emery, D. E. Lycan, K. Y. J. Zhang, and L. L. Breeden. 1998. Mutation and modeling analysis of the Saccharomyces cerevisiae Swi6 ankyrin repeats. Biochemistry 37:4437-4450.
18. Gehrung, S., and M. Snyder. 1990. The SPA2 gene of Saccharomyces cerevisiae is important for pheromone-induced morphogenesis and efficient mating. J. Cell Biol. 111:1451-1454.
19. Ghosh, S., M. J. May, and E. B. Kopp. 1998. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:225-260.
20. Giese, K., C. Kingsley, J. Kirshner, and R. Grosschedl. 1995. Assembly and function of a TCRα enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions. Genes Dev. 9:995-1008.
21. Gietz, D., A. St. Jean, R. A. Woods, and R. H. Schiestl. 1992. Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20:1425.
22. Guthrie, C., and G. R. Fink. 1991. Guide to yeast genetics and molecular biology, vol. 194. Academic Press, Inc., San Diego, Calif.
23. Hagman, J., and R. Grosschedl. 1992. An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene. Proc. Natl. Acad. Sci. USA 89: 8889-8893.
24. Harrington, L. A., and B. J. Andrews. 1996. Binding to the yeast Swi4,6-dependent cell cycle box, CACGAAA, is cell cycle regulated in vivo. Nucleic Acids Res. 24:558-565.
25. Igual, J., A. Johnson, and L. Johnston. 1996. Coordinated regulation of gene expression by the cell cycle transcription factor Swi4 and the protein kinase C MAP kinase pathway for yeast cell integrity. EMBO J. 15:5001-5013.
26. Jonsen, M. D., J. M. Peterson, Q. P. Xu, and B. J. Graves. 1996. Characterization of the cooperative function of inhibitory sequences in Ets-1. Mol. Cell. Biol. 16:2065-2073.
27. Kaiser, C., S. Michaelis, and A. Mitchell. 1994. Methods in yeast genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
28. Koch, C., T. Moll, M. Neuberg, H. Ahorn, and K. Nasmyth. 1993. A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase. Science 261:1551-1557.
29. Koch, C., A. Schleiffer, G. Ammerer, and K. Nasmyth. 1996. Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at Start, whereas Clb/Cdc28 kinases displace it from the promoter in G2. Genes Dev. 10:129-141.
30. Lim, F., N. Kraut, J. Frampton, and T. Graf. 1992. DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanism. EMBO J. 11:643-652.
31. Measday, V., L. Moore, J. Ogas, M. Tyers, and B. Andrews. 1994. The PCL2(ORF2)-PHO85 cyclin dependent kinase complex: a cell cycle regulator in yeast. Science 266:1391-1395.
32. Measday, V., L. Moore, R. Retnakaran, J. Lee, M. Donoviel, A. M. Neiman, and B. Andrews. 1997. A family of cyclin-like proteins that interact with Pho85 cyclin-dependent kinase. Mol. Cell. Biol. 17:1212-1223.
33. Nasmyth, K. 1993. Control of the yeast cell cycle by the Cdc28 protein kinase. Curr. Opin. Cell Biol. 5:166-179.
34. Nasmyth, K., and L. Dirick. 1991. The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66:1015-1026.
35. Ogas, J., B. J. Andrews, and I. Herskowitz. 1991. Transcriptional activation of CLN1, CLN2 and a putative new G1 cyclin (HCS26) by Swi4, a positive regulator of G1 specific transcription. Cell 66:1015-1026.
36. Pardee, A. B. 1989. G1 events and regulation of cell proliferation. Science 244:603-608.
37. Petersen, J., J. Skalicky, L. Donaldson, L. McIntosh, T. Alber, and B. Graves. 1995. Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of α helix. Science 269:1866-1868.
38. Primig, M., S. Sockanathan, H. Auer, and K. Nasmyth. 1992. Anatomy of a transcription factor important for the Start of the cell cycle in Saccharomyces cerevisiae. Nature 358:593-597.
39. Pringle, J. R., A. E. M. Adams, D. G. Drubins, and B. K. Haarer. 1991. Immunofluorescence methods for yeast. Methods Enzymol. 194:565-601.
40. Rabault, B., and J. Ghysdael. 1994. Calcium-induced phosphorylation of ETS1 inhibits its specific DNA binding activity. J. Biol. Chem. 269:28143-28151.
41. Rose, M., and D. Botstein. 1983. Construction and use of gene fusions to lacZ (β-galactosidase) that are expressed in yeast. Methods Enzymol. 101: 167-180.
42. Sedgwick, S. G., I. A. Taylor, A. C. Adam, A. Spanos, S. Howell, B. A. Morgan, M. K. Treiber, N. Kanuga, G. R. Banks, R. Foord, and S. J. Smerdon. 1998. Structural and functional architecture of the yeast cell-cycle transcription factor Swi6. J. Mol. Biol. 281:763-775.
43. 1/S-specific transcription in Saccharomyces cerevisiae. Mol. Cell. Biol. 13:1069-1077.
44. Sidorova, J. M., G. E. Mikesell, and L. L. Breeden. 1995. Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization. Mol. Cell. Biol. 6:1641-1658.
45. Siegmund, R. F., and K. Nasmyth. 1996. The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6. Mol. Cell. Biol. 16:2647-2655.
46. Skalicky, J., L. Donaldson, J. Petersen, B. Graves, and L. McIntosh. 1996. Structural coupling of the inhibitory regions flanking the ETS domain of murine Ets-1. Protein Sci. 5:296-309.
47. Stuart, D., and C. Wittenberg. 1995. CLN3, not positive feedback, determines CLN2 transcription in cycling cells. Genes Dev. 9:2780-2794.
48. Taba, M. R. M., I. Muroff, D. Lydall, G. Tebb, and K. Nasmyth. 1991. Changes in a Swi4,6-DNA binding complex occur at the time of HO activation in yeast. Genes Dev. 5:2000-2013.
49. Taylor, I. A., M. K. Treiber, L. Olivi, and S. J. Smerdon. 1997. The X-ray structure of the DNA-binding domain from the Saccharomyces cerevisiae cell-cycle transcription factor Mbp1 at 2.1A resolution. J. Mol. Biol. 272:1-8.
50. Thompson, C., A. Brown, and S. McKnight. 1991. Convergence of Ets-and Notch-related structural motifs in a heteromeric DNA binding complex. Science 253:762-768.
51. Xu, R. M., C. Koch, Y. Liu, J. R. Horton, D. Knapp, K. Nasmyth, and X. Cheng. 1997. Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis. Structure 5:349-358.
52. YGAC Website. [Online.] http://ycmi.med.yale.edu/YGAC/antibodycleanup .html. [3 August 1999, last date accessed.]