Cigarette smoking and urinary 3-alkyladenine excretion in man

Chemical Research in Toxicology

Volumn 9, Issue 2, 1996, Pages 439-444

  Prevost, Virginie ^a   Shuker, David E G ^a,b  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 ETHYLADENINE; 3 METHYLADENINE; TOBACCO SMOKE; UNCLASSIFIED DRUG;

ADULT; ALKYLATION; ARTICLE; CARCINOGENICITY; CIGARETTE SMOKING; CONTROLLED STUDY; DIETARY INTAKE; DNA ADDUCT; FEMALE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; MALE; NORMAL HUMAN; TOXICOKINETICS; TOXIN ANALYSIS; URINARY EXCRETION;

ADENINE; ADULT; ALKYLATION; DIET; DNA ADDUCTS; FEMALE; HUMANS; MALE; SMOKING;

NICOTIANA TABACUM;

EID: 0029883174     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx9501041     Document Type: Article

References (26)

1. International Agency for Research on Cancer (1986) IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Volume 38: Tobacco Smoking, International Agency for Research on Cancer, Lyon, France.
2. Hecht, S. S., and Hoffmann, D. (1989) The relevance of tobacco-specific nitrosamines to human cancer. Cancer Surv. 8, 273-294.
3. Phillips, D. H., Hewer, A., Martin, C. N., Garner, R. C., and King, M. M. (1988) Correlation of DNA adduct levels in human lung with cigarette smoking. Nature 336, 790-792.
4. Alexandrov, K., Rojas, M., Geneste, O., Castegnaro, M., Camus, A. M., Petruzzelli, S., Guintini, C., and Bartsch, H. (1992) An improved fluorimetric assay for dosimetry of benzo[α]pyrene diolepoxide-DNA adducts in smokers' lung: Comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity. Cancer Res. 52, 6248-6253.
5. 32P-postlabeling assay. Carcinogenesis 14, 545-550.
6. Mustonen, R., and Hemminki, K. (1992) 7-Methylguanine levels in DNA of smokers' and nonsmokers' total white blood cells. granulocytes and lymphocytes. Carcinogenesis 13, 1951-1955.
7. 6-methyldeoxyguanosine in human placental DNA. Cancer Res. 48, 4184-4188.
8. Hecht, S. S., Carmella, S, G., Foiles, P. G., and Murphy, S. E. (1994) Biomarkers for human uptake and metabolic activation of tobacco-specific nitrosamines. Cancer Res. (Suppl.) 54, 1912s-1917s.
9. Foiles, P G., Akerkar, S. A., Carmella, S. G., Kagan, M., Stoner, G. D., Resau, J. H., and Hecht, S. S. (1991) Mass spectrometric analysis of tobacco-specific nitrosamine-DNA adducts in smokers and nonsmokers. Chem. Res. Toxicol. 4, 364-368.
10. Shuker, D. E. G., and Farmer, P. B. (1992) Relevance of urinary DNA adducts as markers of carcinogen exposure. Chem Res. Toxicol. 5, 450-460.
11. Prevost, V., Shuker, D. E. G., Friesen, M. D., Eberle, G., Rajewsky, M. F., and Bartsch, H. (1993) Immunoaffinity purification and gas chromatography-mass spectrometric quantification of 3-alkyladenines in urine: metabolism studies and basal excretion levels in man. Carcinogenesis 14, 199-204.
12. Prevost, V., Shuker, D. E. G., Bartsch, H., Pastorelli, R., Stillwell, W. G., Trudel, L. J , and Tannenbaum, S. R. (1990) The determination of urinary 3-methyladenine by immunoaffinity chromatography-monoclonal antibody-based ELISA: use in human biomonitoring studies. Carcinogenesis 11, 1747-1751.
13. Friesen, M. D., Garren, L., Prevost, V., and Shuker, D. E. G. (1991) Isolation of 3-methyladenine using immunoaffinity columns prior to determination by low-resolution gas chromatography-mass spectrometry. Chem. Res. Toxicol. 4, 102-106.
14. Stillwell, W. G., Glogowski, J., Xu, H. X., Wishnok, J. S., Zavala, D., Montes, G., Correa, P., and Tannenbaum, S. R. (1991) Urinary excretion of nitrate, N-nitrosoproline, 3-methyladenine and 7-methylguanine in a Colombian population at high risk of gastric cancer. Cancer Res. 51, 190-194.
15. Prevost, V., and Shuker, D. E. G (1993) Urinary 3-alkyladenines as markers of tobacco smoke exposure in humans. Hum. Exp. Toxicol. 11, 427-429.
16. Shuker, D. E. G., Prevost, V , Friesen, M. D., Lin, D., Ohshima, H., and Bartsch, H. (1993) Urinary markers for measuring exposure to endogenous and exogenous alkylating agents and precursors Environ. Health Perspect. 99, 33-37.
17. Maxwell, S. E., and Delaney, H. D. (1990) Designing Experiments and Analyzing Data, pp 455-488. Wadsworth Publishing Co., Belmont, CA.
18. Leanderson, P., and Tagesson, C. (1989) Cigarette smoke potentiates the DNA-damaging effect of man-made mineral fibres Am. J. Ind. Med. 16, 697-706.
19. Bailey, E., Brooks, A. G. F , Dollery, C. T., Farmer, P. B., Passingham, B. J., Sleightholm, M. A., and Yates, D. W. (1988) Hydroxyethylvaline adduct formation in haemoglobin as a biological monitor of cigarette smoke intake. Arch. Toxicol. 62, 247-253.
20. Tornqvist, M., Osterman-Golkar, S., Kautiainen, A., Jenesen, S., Farmer, P. B., and Ehrenberg, L. (1986) Tissue doses of ethylene oxide in cigarette smokers determined from adduct levels in hemoglobin. Carcinogenesis 7, 1519-1521.
21. Tavares, R., Ramos, P., Palminha, J., Bispo, M. A., Paz, I , Bras, A., Rueff, J., Farmer, P. B., and Bailey, E. (1994) Transplacental exposure to carcinogens. Evaluation in haemoglobin of hydroxyethylvaline adduct levels in smoking and nonsmoking mothers and their newborns. Carcinogenesis 15, 1271-1274.
22. Segerback, D. (1990) Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea. Carcinogenesis 11, 307-312.
23. Bolt, H. M., Fost, U., Marczynski, B., Golka, K., Hallier, E., and Peter, H. (1991) Ethylene/ethylene oxide and propylene/propylene oxide: an evaluation of human biomonitoring and cancer risk In Human Carcinogen Exposure: Biomonitoring and Risk Assessment (Garner, R C., Farmer, P. B., Steel, G. T., and Wright, A. S., Eds.) pp 223-231, IRL Press, Oxford.
24. 4-ethylthymine in human lung tissue (Abstract). Proc. Am. Assoc. Cancer Res. 36, 136.
25. Hecht, S. S., Spratt, T. E., and Trushin, N. (1988) Evidence for 4-(3-pyridyl)-4-oxobutylation of DNA in F344 rats treated with the tobacco specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N′-nitrosonornicotine. Carcinogenesis 9, 161-165.
26. Kopplin, A., Eberle-Adamkiewicz, G., Glusenkamp, K.-H., Nehls, P., and Kirstein, U (1995) Urinary excretion of 3-methyladenine and 3-ethyladenine after controlled exposure to tobacco smoke. Carcinogenesis 16, 2637-2641.