The discriminative stimulus properties of LY233708, a selective serotonin reuptake inhibitor, in the pigeon

Psychopharmacology

Volumn 146, Issue 3, 1999, Pages 275-279

  Wolff, Mary C ^a   Leander, J David ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

5 HT(1A); Drug discrimination; Pigeon; Selective serotonin reuptake inhibitor

Indexed keywords

1 (6 CHLORO 1,2,3,4 TETRAHYDRO 1 METHYL 2 NAPHTHALENYL)PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CITALOPRAM; FLUOXETINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; NISOXETINE; PIPERAZINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DEPRESSION; DISCRIMINATIVE STIMULUS; DOSE RESPONSE; DRUG STRUCTURE; MALE; NONHUMAN; OBSESSION; PANIC; PIGEON; PRIORITY JOURNAL; PSYCHOTHERAPY; RECEPTOR UPREGULATION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; COLUMBIDAE; CUES; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; PIPERAZINES; PYRIDINES; SEROTONIN UPTAKE INHIBITORS;

EID: 0032870417     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130051117     Document Type: Article

References (25)

1. 2 agonists in rats. Pharmacol Toxicol 64:165-172
2. 1A receptor antagonists BMY7378 and NAN-190. Eur J Pharmacol 217:163-171
3. 1A activity in the discriminative stimulus effects of imipramine. Pharmacol Biochem Behav 38:407-410
4. Berendsen HHG, Broekkamp CLE (1994) Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure. Eur J Pharmacol 253:83-89
5. 1A receptors. Eur J Pharmacol 336:1-6
6. 1A agonist 8-OHDPAT. Psychophamacology 112:121-128
7. 1A receptors. Neurochem Res 21:557-562
8. 1A receptor antagonist. Behav Brain Res 73:337-353
9. Fuller RW (1992) Basic advances in serotonin pharmacology. J Clin Psychiatry 53:36-45
10. Fuller RW, Wong DT (1990) Serotonin uptake and serotonin uptake inhibition. Ann NY Acad Sci 600:68-78
11. Fuller R, Snoddy H, Molloy B (1975) Blockade of amine depletion by nisoxetine in comparison to other uptake inhibitors. Psychopharmacol Commun 1:455-464
12. Hoyer D, Clarke DE, Fozard JR, Hartig PR, Martin GR, Mylecharane EJ, Saxena PR, Humphrey PP (1994) International union of pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharm Rev 46:157-203
13. Jones CN, Howard JL, McBennett ST (1980) Stimulus properties of antidepressants in the rat. Psychopharmacology 67:111-118
14. Lane R, Baldwin D, Preskorn S (1995) The SSRIs: advantages, disadvantages and differences. J Psychopharmacol 9:163-178
15. 1A receptor antagonists enhance the functional activity of fluoxetine in a mouse model of feeding. Brain Res 781:119-126
16. 1D agonist: effects in drug discrimination and punishment procedures. Psychopharmacology 128:313-319
17. Marona-Lewicka D, Nichols DE (1998) Drug discrimination studies of the interoceptive cues produced by selective serotonin uptake inhibitors and selective serotonin releasing agents. Psychopharmacology 138:67-75
18. Millan MJ, Gobert A, Girardon S, Dekeyne A (1999) Citalopram elicits a discriminative stimulus in rats at a dose selectively increasing extracellular levels of serotonin vs. dopamine and noradrenaline. Eur J Pharmacol 364:147-150
19. Nixon JA, Pioch RP, Bymaster FP, Reid L, Wong DT, Hemrick-Luecke SK, Fuller RW (1989) SAR and pharmacological activity of LY233708, a potent and selective inhibitor of serotonin reuptake. 197th National American Chemical Society Meeting, Dallas, TX
20. Schaus JM, Nixon JA, Titus RD, Pioch R, Wong DT, Fuller RW (1989) Piperazinyltetralins: a new class of potent and selective serotonin reuptake inhibitors. NYAS Conference on Neuro-pharmacology of Serotonin, New York
21. Schreiber R, Brocco M, Millan MJ (1994) Blockade of the discriminative stimulus effects of DOI by MDL 100907 and the 'atypical' antipsychotics, clozapine and risperidone. Eur J Pharmacol 264:99-102
22. Sherman G, Miksic S, Lal H (1978) Discriminative stimulus properties of desipramine. Neuropharmacology 17:1045-1048
23. 1A receptor ligands by drag discrimination. Eur J Pharmacol 333:113-122
24. Wolff Mc, Leander JD (1998) Selective serotonin reuptake inhibitors potentiate 8-OH-DPAT-induced stimulus control in the pigeon. Eur J Pharmacol 345:35-39
25. Zhang L, Barrett JE (1991) Imipramine as a discriminative stimulus. J Pharmacol Exp Ther 259:1088-1093