Recent advances in immunology of Type 1 diabetes mellitus: A congenital disorder?

Diabetes, Nutrition and Metabolism - Clinical and Experimental

Volumn 12, Issue 2, 1999, Pages 68-74

  Bruining, G Jan ^a,b   Batstra, M R ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Apoptosis; Diabetes mellitus; Fetal diseases; HLA; Insulin dependent; Pathologic processes

Indexed keywords

HLA A ANTIGEN; MICROSATELLITE DNA;

APOPTOSIS; GENETIC RISK; GENETIC SUSCEPTIBILITY; HLA SYSTEM; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; REVIEW;

EID: 0032861719     PISSN: 03943402     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (31)

1. De Krijger R.R., Aanstoot H.J., Kranenburg G., Reinhard M., Visser W., Bruining G.J.: The midgestational human fetal pancreas contains cells coexpressing islet hormones. Develop. Biol. 153: 368-375, 1992.
2. Åkerblom H.K., Knip M.: Putative environmental factors in type 1 diabetes. Diabetes Metab. Rev. 14: 31-67, 1998.
3. Green A., Gale E.A., Patterson C.C.: Incidence of childhood-onset insulin-dependent diabetes mellitus: the Eurodiab ACE study. Lancet 339: 905-909, 1992.
4. Dahlquist G.: Primary and secondary prevention strategies of pre-type 1 diabetes. Diabetes Care 22 (Suppl. 22): 4-6, 1999.
5. Bruining G.J.: Studies on childhood diabetes mellitus. Thesis Erasmus University, Rotterdam, 1984, p. 101.
6. Lesley R.D.G., Atkinson M.A., Notkins A.L.: Autoantigens IA-2 and GAD in type 1 (insulin dependent) diabetes mellitus. Diabetologia 42: 3-14, 1999.
7. Baxter A.G.: Immunogenetics and the cause auto-immune disease. Autoimmunity 25: 177-189, 1997.
8. Dahlquist G., Ivarsson S., Lindberg B., Forsgren M.: Maternal enteroviral infection during pregnancy as a risk factor for childhood IDDM. Diabetes 44: 408-413, 1995.
9. Nerup J., Mandrup-Poulsen T., Molvig J., Spinas G.: Immune reactions with islet cells: implications for the pathogenesis of insulin dependent diabetes mellitus. In: Lefebre P.J., Pipeleers D.G. (Eds), The pathology of the endocrine pancreas in diabetes. Springer-Verlag, Berlin, 1988, pp. 71-84.
10. Bottazzo G.F.: Death of a beta cell: homicide or suicide? Science 248: 1380-1388, 1986.
11. Conrad B., Weidmann E., Trucco G., Rudert W.A., Behboo R., Ricordi C., Rodriguez-Rilo H., Feingold D., Trucco M.: Evidence for a superantigen in insulin dependent diabetes aetiology. Nature 371: 351-355, 1994.
12. Homo-Delarche F.H., Boitard C.: Auto-immunity diabetes: the role of the islets of Langerhans. Immunol. Today 17: 456-460, 1996.
13. Homo-Delarche F.H.: Beta cell behaviour during the prediabetic stage. Part 1. Beta pathophysiology. Diabetes Metab. 23: 181-194, 1997.
14. Lindberg B., Ivarsson S.A., Landin-Olsson M., Sundkvist G., Svanberg L., Lernmark A.: Islet autoantibodies in cord blood from children who developed Type 1 (insulin-dependent) diabetes mellitus before 15 years of age. Diabetologia 42: 181-187, 1999.
15. De Krijger R.R., Aanstoot J.J., Kranenburg G., Verkerk A., Jongkind J.F., Van Strik R., Lafferty K.J., Bruining G.J.: Enrichment of beta-cells from the human fetal pancreas by fluorescence activated cell sorting using a new monoclonal antibody. Diabetologia 35: 436-443, 1992.
16. Jacobson M.D., Weil M., Raff M.C.: Programmed cell death in animal development. Cell 88: 347-354, 1997.
17. Suda T., Takashashi T., Goldstein P., Nagata S: Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis family. Cell 75: 1169-1178, 1993.
18. Throsby M., Homo-Delarche F.H., Chevenne D., Goya R., Dardenne M., Pleau J.M.: Pancreatic hormone expression in the murine thymus: localization in dendritic cells and macrophages. Endocrinology 139: 2399-2406, 1997.
19. Tong Z., Ling S., Pingar Y., Zheng W., Di L., Jope R.S.: Bisindolylmaleimide VIII facilitates Fas mediated apoptosis and inhibits T-cell-mediated auto-immune diseases. Nat. Med. 5: 42-48, 1999.
20. Sang-Mo K., Schneider D.B., Zhongghua L., Hanahan D., Dichek D.A., Stock P.G., Baekkeskov S.: Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction. Nat. Med. 3: 738-743 1997.
21. Todd J.A., Farall M.: Planning for gold: genome wide scanning for linkage in type 1 diabetes. Hum. Mol. Genet. 5: 14443-14448, 1996.
22. Kumar D., Gemayel N.B., Deapen D.: North American twins with IDDM. Genetical and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis of the first twin. Diabetes 42: 1351-1362, 1993.
23. In't Veld P.A., Bruining G.J.: Genetic syndromes associated with diabetes mellitus. In: Pickup J.C., Williams G. (Eds), Textbook of Diabetes, ed. 2. Oxford Blackwell Scientific, Oxford, 1996, pp. 1204-1210.
24. Apanius V., Penn D., Slev P.R., Ruff R., Potts W.: The nature of selection on the major histocompatibility complex. Crit. Rev. Immunol. 17: 179-224, 1997.
25. Ronningen K.S.: Genetics in the prediction of insulin-dependent diabetes mellitus: from theory to practice. Ann. Med. 29: 387-392, 1997.
26. Todd J.A., Bell J.I., McDevitt H.O.: A molecular basis for genetic susceptibility to insulin dependent diabetes. Trends Genet. 4: 129-134, 1988.
27. Jackson D.G., Capra J.D.: TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility. Proc. Natl. Acad. Sci. 90: 11079-11083, 1993.
28. Foissac A., Crouau-Roy B., Cambon-Thomsen A., Thomsen M.: Microsatellites in the MHC region: an overview. Tissue Antigens 49: 197-214, 1996.
29. Moghaddam P.H., Zwinderman A.H., De Knijff P., Roep B.O., Naipal A., Schipper R.F., Van der Auwerda B., Gorus F., Giphart M., the Belgian Registry: D6STNFa microsatellite polymorphism modulates the risk of IDDM in caucasians with the high risk genotype HLA-DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302. Diabetes 46: 1541-1515, 1997.
30. Verge C.F., Gianani R., Kawasaki E., Yen L., Pietropaolo M, Jackson R.A., Chase H.P., Eisenbarth G.S.: Prediction of type 1 diabetes in first degree relatives using a combination of insulin, GAD and ICA512 bdc/IA2 autoantibodies. Diabetes 45: 926-933, 1996.
31. Bruining G.J., Grobbee G.E., Molenaar J.L., Scheffer G.J., de Bruyn A.M., Hofman A., Bruining H.A., Valkenburg H.A.: Ten year follow up study of islet-cell antibodies and childhood diabetes mellitus. Lancet I: 1100-1103, 1989.