The cellular ionic basis of hypertension and allied clinical conditions

Progress in Cardiovascular Diseases

Volumn 42, Issue 1, 1999, Pages 1-22

  Resnick, L ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; INSULIN; ION; MAGNESIUM ION;

BLOOD PRESSURE REGULATION; CALCIUM INTAKE; CALCIUM MOBILIZATION; CARDIOVASCULAR AUTOREGULATION; GLUCOSE METABOLISM; HUMAN; HYPERTENSION; PATHOPHYSIOLOGY; REVIEW; SODIUM BALANCE; SYNDROME X;

EID: 0032860330     PISSN: 00330620     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0033-0620(99)70006-X     Document Type: Article

References (132)

1. LM Resnick Ionic disturbances of calcium and magnesium metabolism in essential hypertension ed 2 JH Laragh BM Brenner Hypertension: Pathophysiology, Diagnosis, and Management 1995 Raven Press New York, NY 1169 1191
2. JH Laragh LM Resnick Recognizing and treating two types of long-term vasoconstriction in hypertension Kidney Int 34 suppl 25 1988 S162 S174
3. T Fujita WL Henry FC Bartter Factors influencing blood pressure in salt-sensitive patients with hypertension Am J Med 69 1980 334 344
4. P Erne P Bolli O Bertel Factors influencing the antihypertensive effects of calcium antagonists Hypertension 5 suppl II 1983 II-97 II-102
5. S Sheps The Sixth Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure 1997 National Institutes of Health Bethesda, MD
6. S Ringer A third contribution regarding the infusion of the inorganic constituents of the blood on the ventricular contraction J Physiol (Lond) 4 1883 222 225
7. K Hermsmeyer P Erne Vascular muscle ion channels and cellular calcium regulation in hypertension ed 2 JH Laragh BM Brenner Hypertension: Pathophysiology, Diagnosis, and Management 1995 Raven Press New York, NY 673 683
8. RA Khalil C van Breeman Mechanisms of calcium mobilization and homeostasis in vascular smooth muscle and their relevance to hypertension ed 2 JH Laragh BM Brenner Hypertension: Pathophysiology, Diagnosis, and Management 1995 Raven Press New York, NY 523 539
9. RP Rubin The role of calcium in the release of neurotransmitter substances and hormones Pharmacol Rev 22 1970 389 427
10. L Resnick Role of calcium and magnesium in the therapy of human hypertension J Laragh B Brenner Hypertension: Pathophysiology, Diagnosis, and Management. 1990 Raven Press New York, NY 2037 2059
11. BM Altura BT Altura Magnesium ions and contraction of vascular smooth muscles: Relationship to some vascular diseases Federation Proc 40 1981 2672 2679
12. P Erne P Bolli E Burgissen F Buhler Correlation of platelet calcium with blood pressure: Effect of antihypertensive therapy N Engl J Med 319 1984 1084 1088
13. LM Resnick RK Gupta JH Laragh Intracellular free magnesium in erythrocytes of essential hypertension: Relation to blood pressure and serum divalent cations Proc Natl Acad Sci USA 81 1984 6511 6515
14. L Resnick R Gupta K Bhargava Cellular ions in hypertension, diabetes, and obesity: A nuclear magnetic resonance spectroscopic study Hypertension 17 1991 951 957
15. 2+ transport in permeabilized human neutrophils Clin Sci 74 1988 53 56
16. A Lindner M Kenny AJ Meachem Effects of a circulating factor in patients with essential hypertension on intracellular free calcium in normal platelets N Engl J Med 316 1987 509 513
17. M Barbagallo RK Gupta O Bardicef Altered ionic effects of insulin in hypertension: Role of basal ion levels in determining cellular responsiveness J Clin Endocrinol Metab 82 1997 1761 1765
18. LM Resnick DM Militianu AJ Cunnings Direct magnetic resonance determination of aortic distensibility in essential hypertension: Relation to age, abdominal visceral fat, and in situ intracellular free magnesium Hypertension 30 1997 654 659
19. L Resnick M Roman R Gupta Intracellular cation determinants of left ventricular mass Am J Hypertens 3 1990 15A (abstr)
20. M Barbagallo RK Gupta L Dominguez LM Resnick Cellular ionic alterations with aging: Relation to hypertension and diabetes Hypertension 33 1999 1067 (abstr)
21. M Barbagallo RK Gupta LM Resnick Cellular ions in NIDDM: Relation of calcium to hyperglycemia and cardiac mass Diabetes Care 19 1996 1393 1398
22. LM Resnick RK Gupta B DiFabio Intracellular ionic consequences of dietary salt loading in essential hypertension: Relation to blood pressure and effects of calcium channel blockade J Clin Invest 94 1994 1269 1276
23. LM Resnick JP Nicholson RK Gupta JH Laragh Interactive effects between oral calcium supplementation and calcium antagonist therapy in essential hypertension J Hypertens 11 suppl 5 1993 S472
24. P Lijnen V Petrov Dietary calcium, blood pressure and cell membrane cation transport systems in males J Hypertens 13 1995 875 882
25. DB Jacobs JR Sowers A Hmeidan Effects of weight reduction on cellular cation metabolism and vascular resistance Hypertension 21 1993 308 314
26. L Resnick M Roman R Gupta Intracellular cation determinants of left ventricular mass Am J Hypertens 3 1990 15A (abstr)
27. 31P-NMR spectroscopic studies of oral glucose loading and in situ skeletal muscle ion content in essential hypertension Hypertension 26 1995 552 (abstr)
28. L Resnick R Gupta H Gruenspan Hypertension and peripheral insulin resistance: Mediating role of intracellular free magnesium Am J Hypertens 3 1990 373 379
29. G Paolisso D Galzerano A Gambardella Low fasting and insulin-mediated intracellular magnesium accumulation in hypertensive patients with left ventricular hypertrophy: Role of insulin resistance J Hum Hypertens 9 1995 199 203
30. H Roslova O Mayer Jr G Reaven Effect of variations in plasma magnesium concentration on resistance to insulin-mediated glucose disposal in non-diabetic subjects J Clin Endocrinol Metab 82 1997 3783 3785
31. B Draznin K Sussman M Kao The existance of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes J Biol Chem 262 1987 14385 14388
32. B Draznin K Sussman R Eckel Possible role of cytosolic free calcium in mediating insulin resistance of obesity and hyperinsulinemia J Clin Invest 82 1988 1848 1852
33. B Draznin Cytosolic calcium: A new factor in insulin resistance? Diabetes Res Clin Pract 11 1991 141 146
34. LM Resnick Cellular ions in hypertension, insulin resistance, obesity, and diabetes: A unifying theme J Am Soc Nephrol 3 suppl 1 1992 S78 S85
35. LM Resnick M Barbagallo Ionic basis of Syndrome X Y Matsuzawa Y Akanuma Diabetes Mellitus, Obesity and Hyperlipidemia. 1996 Axel Springer Tokyo, Japan 19 23
36. H Kuriyama I Uyshi H Sueuk Factors modifying contraction-relaxation cycle in vascular smooth muscles Am J Physiol 243 1982 H641 H662
37. BM Altura BT Altura A Gebrewold Magnesium deficiency and hypertension: Correlation between magnesium-deficient diets and microcirculatory changes in situ Science 223 1984 1315 1317
38. I Inoue H Matsuura T Kawagoe Role of intracellular cation abnormalities in development of left ventricular hypertrophy J Cardiovasc Pharmacol 17 suppl 2 1991 s107 s109
39. 2+ handling in isolated rat myocardium Am J Physiol 274 1998 H1361 H1370
40. L Resnick Ionic hypothesis: The link between hypertension, obesity, insulin resistance, and left ventricular hypertrophy Practical Cardiol 16 1990 36 42
41. LM Resnick Ionic basis of hypertension, insulin resistance, vascular disease, and related disorders: Mechanism of Syndrome X Am J Hypertens 6 1993 123s 134s
42. JK Rockstroh HP Schobel G Vogt-Ladner Blood pressure independent effects of nitrendipine on cardiac structure in patients after renal transplantation Nephrol Dial Transplant 12 1997 1441 1447
43. MA Sussman HW Lim N Gude Prevention of cardiac hypertrophy in mice by calcineurin inhibition Science 281 1998 1690 1693
44. DL Curry LL Bennett GM Grodsky Requirement for calcium ion in insulin secretion by the perfused rat pancreas Am J Physiol 214 1968 174 181
45. B Hellman J Sehlin JB Taljedal Calcium and secretion: Distinction between two pools of glucose-sensitive calcium in pancreatic islets Science 194 1976 1421 1423
46. M Hoenig GW Sharp Glucose induces insulin release and a rise in cytosolic calcium concentration in a transplantable rat insulinoma Endocrinology 119 1986 2502 2507
47. YS Ahn W Jy W Harrington Increased platelet calcium in thrombosis and related disorders and its correction by nifedipine Thromb Res 45 1987 135 143
48. 2+ handling in arterial thrombosis Thromb Haemost 57 1987 1 10
49. RP Rubin The role of calcium in the release of neurotransmitter substances and hormones Pharmacol Rev 22 1970 389 427
50. S Julius T Gudbrandsson K Jamerson O Andersson The interconnection between sympathetics, microcirculation and insulin resistance in hypertension Blood Press 1 1992 9 19
51. M Barbagallo LM Resnick RE Sosa Renal divalent cation excretion in secondary hypertension Clin Sci 83 1992 561 565
52. M Barbagallo LJ Dominguez E Putignano Effect of aging on intracellular divalent cation metabolism: A link to the increased incidence of hypertension and non-insulin dependent diabetes mellitus in the elderly? Arch Gerontol suppl 5 1996 233 238
53. Y Saimi C Kung Are ions involved in gating of calcium channels? Science 218 1982 153 156
54. PG Kostyuk OA Krishtal Effects of calcium and calcium-chelating agents on the inward and outward current in the membrane of mollusc neurones J Physiol (Lond) 270 1997 569 580
55. 2+ content Am J Physiol 273 1997 C1666 C1672
56. G Rinaldi DF Bohr Potassium-induced relaxation of arteries in hypertension: Modulation by extracellular calcium Am J Physiol 25 1989 H707 H712
57. LM Resnick JP Nicholson RM Marion Intravenous calcium in essential hypertension: Role of intracellular ions in determining ionic and blood pressure responsiveness Hypertension 30 1997 469 (abstr)
58. DF Bohr What makes the pressure go up? A Hypothesis Hypertension 3 suppl II 1981 II-160 II-165
59. 2+ indicator Mag-Indo-1 Cell Calcium 19 1996 391 398
60. X Ruan WJ Arendshorst Calcium entry and mobilization signaling pathways in ANG II-induced renal vasoconstriction in vivo Am J Physiol 270 1996 F398 F405
61. A Verkhratsky A Shmigol Calcium-induced calcium release in neurones Cell Calcium 19 1996 1 14
62. MP Blaustein M Juhaszova VA Golovina The cellular mechanism of action of cardiotonic steroids: A new hypothesis Clin Exp Hypertens 20 1998 691 703
63. 2+ current by sarcoplasmic reticulum of guinea pig urinary bladder myocytes Am J Physiol 271 1996 C833 C841
64. AP Somlyo Editorial focus: How many messegers to send calcium? Am J Physiol 274 1998 C1453 C1455
65. DE Clapham Calcium signaling Cell 80 1995 259 268
66. 2+ release in vascular endothelial cells Am J Physiol 273 1997 C1775 C1782
67. 2+ produced by angiotensin II in cultured arterial muscle cells J Biol Chem 262 1987 17455 17460
68. NR Sharma MJ Davis Calcium entry activated by store depletion in coronary endothelium is promoted by tyrosine phosphorylation Am J Physiol 270 1996 H267 H274
69. 2+ pump in endothelium Am J Physiol 274 1998 C1117 C1128
70. 2+ stores in human platelets J Physiol (Lond) 479 1994 1 10
71. 2+ entry by noradrenaline involves cGMP in vascular myocytes Cell Calcium 18 1995 505 514
72. L Resnick J Laragh J Sealey M Alderman Divalent cations in essential hypertension. Relations between serum ionized calcium, magnesium, and plasma renin activity N Engl J Med 309 1983 888 891
73. L Resnick F Muller J Laragh Calcium regulating hormones in essential hypertension: Relation to plasma renin activity and sodium metabolism Ann Intern Med 105 1986 649 654
74. SC Hunt RR Williams H Kuida Different plasma ionized calcium correlations with blood pressure in high and low renin normotensive adults in Utah Am J Hypertens 4 1991 1 8
75. 2+ load Hypertension 31 1998 595 602
76. L Resnick J Nicholson J Laragh Calcium, the renin-angiotensin system, and the hypotensive response to nifedipine Hypertension 10 1987 254 258
77. M Baudouin P Meyer S Fermandjian JL Morgat Calcium release induced by interaction of angiotensin with its receptors in smooth muscle cell microsomes Nature 235 1972 336 338
78. 2+ kinetics and contraction in cultured rat glomerular mesangial cells Am J Physiol 254 1988 F254 F266
79. L Resnick J Nicholson J Laragh Alterations in calcium metabolism mediate dietary salt sensitivity in essential hypertension Trans Assoc Am Physicians 98 1985 313 321
80. LM Resnick RZ Lewanczuk JH Laragh PKT Pang Parathyroid hypertensive factor-like activity in human essential hypertension: Relationship to plasma renin activity and dietary salt sensitivity J Hypertens 11 1993 1235 1241
81. VM Campese MS Romoff D Levitan Abnormal relationship between sodium intake and sympathetic nervous system activity in salt-sensitive patients with essential hypertension Kidney Int 21 1982 371 378
82. T Fujita WL Henry FC Bartter Factors influencing blood pressure in salt-sensitive patients with hypertension Am J Med 69 1980 334 344
83. BS Huang FHH Leenen Smpathoexcitatory and pressor responses to increased brain sodium and oubain are mediated vis brain ANG II Am J Physiol 270 1996 H275 H280
84. YF Chen Q Meng JM Wyss High NaCl diet reduces hypothalamic norepinephrine turnover in hypertensive rats Hypertension 11 1988 55 62
85. K Ishibashi T Oshima H Matsuura Effect of age and sex on sodium chloride sensitivity: Association with plasma renin activity Clin Nephrol 42 1994 376 380
86. P van Paassen D de Zeeuw G Navis PE de Jong Does the renin-angiotensin system determine the renal and systemic hemodynamic response to sodium in patients with essential hypertension? Hypertension 27 1996 202 208
87. J Sealey J Blumenfeld M Bell Presidential Address. On the renal basis for essential hypertension: Nephron heterogeneity with discordant renin secretion and sodium excretion causing a hypertensive vasoconstriction-volume relationship J Hypertens 6 1988 763 777
88. N Hollenberg G Williams Abnormal renal sodium handling in essential hypertension: Relation to failure of renal and adrenal modulation of responses to angiotensin II Am J Med 81 1986 412 418
89. J Shan LM Resnick RZ Lewanczuk 1,25 Dihdroxyvitamin D as a cardiovascular hormone: Effects on calcium current and cytosolic free calcium in vascular smooth muscle cells Am J Hypertens 6 1993 983 988
90. LM Resnick RZ Lewanczuk JH Laragh PKT Pang Parathyroid hypertensive factor-like activity in human essential hypertension: Relationship to plasma renin activity and dietary salt sensitivity J Hypertens 11 1993 1235 1241
91. 45Ca uptake by primary cultures of aortic myocytes of spontaneously hypertensive and Wistar Kyoto normotensive rats Biochem Biophys Res Commun 146 1987 1330 1335
92. 3 Am J Hypertens 6 1993 389 396
93. L Resnick B DiFabio R Marion Dietary calcium modifies the pressor effects of dietary salt intake in essential hypertension J Hypertens 4 suppl 6 1986 S679 S681
94. A Lasaridis K Zanieri C Kaisis Oral calcium supplementation promotes renal sodium excretion in essential hypertension J Hypertens 5 suppl 5 1987 S307 S309
95. Y Tabuchi T Ogihara H Saito Y Kumahara Hypotensive effect of long-term oral calcium supplementation in elderly patients with essential hypertension J Clin Hypertens 3 1986 254 262
96. K Saito H Sano Y Furuta H Fukuzaki Effect of oral calcium on blood pressure response in salt-loaded borderline hypertensive patients Hypertension 13 1989 219 226
97. P Lijnen V Petrov Dietary calcium, blood pressure and cell membrane cation transport systems in males J Hypertens 13 1995 875 882
98. T Ogihara H Saito Y Tabuchi The hypotensive effect of long-term oral calcium loading in elderly hypertensive patients: The importance of endogenous vitamin D suppression J Hypertens 4 suppl 6 1986 S685 S687
99. LM Resnick Alterations of dietary calcium intake as a therapeutic modality in essential hypertension Can J Physiol Pharmacol 64 1986 803 807
100. LJ Appel TJ Moore E Obarzanek A clinical trial of the effects of dietary patterns on blood pressure N Engl J Med 336 1997 1117 1124
101. DA McCarron S Oparil A Chait Nutritional management of cardiovascular risk factors Arch Intern Med 157 1997 169 177
102. LM Resnick DA McCarron S Oparil VS Group Effects of comprehensive nutrition intervention in essential hypertension: Role of calcium metabolism J Am Soc Nephrol 7 1996 1555 (abstr)
103. L Resnick J Nicholson J Laragh Alterations in calcium metabolism mediate dietary salt sensitivity in essential hypertension Trans Assoc Am Physicians 98 1985 313 321
104. L Resnick J Nicholson J Laragh Calcium metabolism and essential hypertension-relation to altered renin system activity Federation Proc 45 1986 2739 2745
105. P Hamet M Daignault-Gelinas J Lambert Epidemiological evidence of an interaction between calcium and sodium intake impacting on blood pressure. A Montreal Study Am J Hypertens 5 1992 378 385
106. LM Resnick M Barbagallo RK Gupta JL Laragh Ionic basis of hypertension in diabetes mellitus: Role of hyperglycemia Am J Hypertens 6 1993 296 301
107. M Barbagallo J Shan PKT Pang LM Resnick Glucose-induced alterations of cytosolic free calcium in cultured rat tail artery vascular smooth muscle cells J Clin Invest 95 1995 763 767
108. LM Resnick Ionic disturbances of calcium and magnesium metabolism in essential hypertension ed 2 JH Laragh BM Brenner Hypertension: Pathophysiology, Diagnosis, and Management 1995 Raven Press New York, NY 1169 1191
109. M Coutinho Y Wang HC Gerstein F Yusuf Continuous relationship of glucose with cardiovascular events in non-diabetic subjects: A meta-regression analysis of 18 studies in 88,000 individuals Circulation 94 suppl 1 1996 I214
110. K Zierler F Wu Insulin acts on Na, K, and Ca currents Trans Assoc Am Physicians 101 1988 320 325
111. B Draznin M Kao K Sussman Insulin and glyburide increase cytosolic free calcium concentration in isolated rat adipocytes Diabetes 36 1987 174 178
112. M Barbagallo RK Gupta LM Resnick Cellular ionic effects of insulin in normal human erythrocytes: A nuclear magnetic resonance study Diabetologia 36 1993 146 149
113. DL Hwang CF Yen JL Nadler Insulin increases intracellular magnesium transport in human platelets J Clin Endocrinol Metab 76 1993 549 553
114. ++ transport in cultured vascular smooth muscle cells from spontaneously hypertensive rats Am J Hypertens 5 1992 892 895
115. M Barbagallo PA August LM Resnick Altered cellular calcium responsiveness to insulin in normotensive and hypertensive pregnancy J Hypertens 14 1996 1081 1085
116. JM Olefsky JJ Nolan Insulin resistance and non-insulin dependent diabetes mellitus: Cellular and molecular mechanisms Am J Clin Nutr 61 suppl 1995 980s 986s
117. TA Buchanan WP Meehan YY Jeng Blood pressure lowering by pioglitazone. Evidence for a direct vascular effect J Clin Invest 96 1995 354 360
118. HA Pershadsingh J Szollosi S Benson Effects of ciglitazone on blood pressure and intracellular calcium metabolism Hypertension 21 1993 1020 1023
119. R Komers A Vrana Thiazolidinediones—Tools for the research of metabolic syndrome X Physiol Res 47 1998 215 225
120. J Nadler S Scott Evidence that pioglitazone increases intracellular free magnesium concentration in freshly isolated rat adipocytes Biochem Biophys Res Commun 202 1994 416 421
121. A Haenni L Berglund R Reneland The alterations in insulin sensitivity during angiotensin converting enzyme inhibitor treatment are related to changes in the calcium/magnesium balance Am J Hypertens 10 1997 145 151
122. M Kornfeld AM Gutierrez E Gonzalez Cell calcium concentration in glomerular afferent and efferent arterioles under the action of noradrenaline and angiotensin II Acta Physiol Scand 151 1994 99 105
123. A Romani C Marfella A Scarpa Regulation of magnesium uptake and release in the heart and in isolated ventricular myocytes Circ Res 72 1993 1139 1148
124. (2+)-dependent fashion from undifferentiated HL-60 cells Cell Calcium 17 1995 399 408
125. C Warnotte P Gilon M Nenquin JC Henquin Mechanisms of the stimulation of insulin release by saturated fatty acids. A study of palmitate effects in mouse beta-cells Diabetes 43 1994 703 711
126. 2+ mobilization and superoxide production induced by very-long-chain fatty acids Biochem J 311 1995 689 697
127. R Locher A Sachinidis C Brunner W Vetter Intracellular free calcium concentration and thromboxane A2 formation of vascular smooth muscle cells are influenced by fish oil and n-3 eicosapentanoic acid Scand J Lab Clin Invest 51 1991 541 547
128. A Sachinidis R Locher W Vetter Generation of intracellular signals by low density lipoprotein is independent of classical LDL receptor Am J Hypertens 4 1991 274 279
129. A Fleckenstein M Frey F Thimm G Fleckenstein-Grun Excessive mural calcium overload-a predominant causal factor in the development of stenosing coronary plaques in humans Cardiovasc Drugs Ther 4 suppl 5 1990 1005 1013
130. BT Altura M Brust S Bloom Magnesium dietary intake modulates blood lipid levels and atherogenesis Proc Natl Acad Sci USA 87 1990 1840 1844
131. JH Laragh Vasoconstriction-volume analysis for understanding and treating hypertension: The use of renin and aldosterone profiles Am J Med 55 1973 261 274
132. PC Churchill Second messengers in renin secretion Am J Physiol 249 1985 F175 F184