Tolerance and auto-immunity: 50 Years after Burnet

European Journal of Pediatrics

Volumn 158, Issue 10, 1999, Pages 769-775

  Martini, A ^a   Burgio, G R ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Auto immunity; Immune tolerance

Indexed keywords

ANTIBODY; ANTIGEN;

ANTIGEN RECOGNITION; AUTOIMMUNE DISEASE; AUTOIMMUNITY; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CLONAL ANERGY; HELPER CELL; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; LYMPHOCYTE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

AUTOIMMUNE DISEASES; BONE MARROW TRANSPLANTATION; CYTOKINES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNE TOLERANCE; T-LYMPHOCYTES;

EID: 0032859749     PISSN: 03406199     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004310051201     Document Type: Review

References (58)

1. Abbas AK, Murphy KM, Sher A (1996) Functional diversity of helper T lymphocytes. Nature 383:787-793
2. Albani S, Carson DA (1996) A multistep molecular mimicry hypothesis for the pathogenesis of rheumatoid arthritis. Immunol Today 17:466-470
3. Albani S, Keystone EC, Nelson JL, Ollier WER, La Cava A, Montemayor AC, Weber DA, Montecucco C, Martini A, Carson DA (1995) Positive selection in autoimmunity: abnormal immune responses to bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis. Nat Med 1:448-452
4. Billingham RE, Lampkin GH, Medawar PB, Williams HL (1952) Tolerance to homografts, twin diagnosis, and the freemartin condition in cattle. Heredity 6:201-212
5. Billingham RE, Brent L, Medawar PB (1953) Actively acquired tolerance of foreign cells. Nature 172:603-606
6. Brocke S, Gaur A, Piercy C, Gautam A, Gijbels K, Fatman CG, Steinman L (1993) Induction of relapsing paralysis in experimental autoimmune encephalomyelitis by bacterial superantigen. Nature 365:642-644
7. Burgio GR, Martini A (1990) Immunological features of diffuse connective tissue diseases. Eur J Pediatr 149:224-231
8. Burgio GR, Nespoli L (1989) A notation on individuality, 50 years after the death of Sigmund Freud. Toward a biological Ego? Eur J Pediatr 149:9-10
9. Burnet FM (1957) A modification of Jerne's theory of antibody production using the concept of clonal selection. Aust J Sci 20:67-69
10. Burnet FM (1959) The clonal selection theory of acquired immunity. Cambridge University Press, Cambridge
11. Burnet FM (1961) The new approach to immunology. N Engl J Med 264:24-34
12. Burnet FM (1969) Self and non-self, Cambridge University Press, Cambridge
13. Burnet FM (1972) Autoimmunity and autoimmune disease. Medical and Technical Publishing, Lancaster
14. Burnet FM, Fenner F (1949) The production of antibodies, 2nd edn. Macmillian, Melbourne
15. Cohen IR (1992) The cognitive principle challenges clonal selection. Immunol Today 13:441-444
16. Cohen IR (1992) The cognitive paradigm and the immunological homunculus. Immunol Today 13:490-494
17. Cohn M (1994) The wisdom of hindsight. Annu Rev Immunol 12:1-62
18. Doniach D, Roitt IM (1957) Autoimmunity in Hashimoto disease and its implication. J Clin Endocrinol Metab 17:1293
19. Dresser DW (1961) Effectiveness of lipid and lipidophilic substances as adjuvants. Nature 191:1169-1171
20. Dresser DW (1962) Specific inhibition of antibody production. II. Paralysis induced in adult mouse by small quantities of protein antigen. Immunology 5:378-388
21. Ehrlich P, Morgenroth J (1901) Uber Hamolysine: Funfte Miittheilung. Berlin klin Wochenschr 38:251-256
22. Fisher GH, Rosenberg FJ, Straus SE, Dale JK, Middleton LA, Lin AY, Strober W, Lenardo MJ, Puck JM (1995) Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune Imphoproliferative syndrome. Cell 81:935-946
23. Genain CP, Abel K, Belmar N, Villinger F, Rosenberg DP, Linington C, Raine CS, Hauser SL (1996) Late complications of immune deviation therapy in a nonhuman primate. Science 274:2054-2057
24. Goodnow CC (1996) Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci USA 93:2264-2271
25. Gregersen PK (1997) Genetic analysis of rheumatic diseases. In: Kelley WN, Ruddy S, Harris ED, Sledge CB (eds) Textbook of rheumatology. W.B. Saunders, Philadelphia, pp 209-227
26. Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, Vries JA de, Roncarolo MG (1997) A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389:737-742
27. Horwitz MS, Bradley LM, Harbertson J, Krahl T, Lee J, Sarvetnick N (1998) Diabetes induced by Coxsackie virus: Initiation by bystander damage and not molecular mimicry. Nat Med 4:781-785
28. Janeway CA Jr (1992) The immune system evolved to discriminate infectious nonself from noninfectious self. Immunol Today 13:11-16
29. Jerne NK (1955) The natural selection theory of antibody formation. Proc Natl Acad Sci USA 41:849-857
30. Jerne NK (1974) Towards a network theory of the immune system. Ann Immunol (Paris) 125:373-389
31. Kalden JR, Sieper J (1998) Oral collagen in the treatment of rheumatoid arthritis. Arthritis Rheum 41:191-194
32. Klein J (1982) Immunology: the science of self-nonself discrimination. Wiley, New York
33. Liblau R, Tisch R, Bercovici N, McDevitt HO (1997) Systemic antigen in the treatment of T-cell-mediated autoimmune diseases. Immunol Today 18:599-604
34. Mackay IR (1992) Autoimmunity: paradigms of Burnet and complexities of today. Immunol Cell Biol 70:159-171
35. Maclaren NK, Atkinson MA (1997) Insulin-dependent diabetes mellitus: the hypothesis of molecular mimicry between islet cell antigens and microorganisms. Mol Med Today 2:76-83
36. Marmont AM, Van Bekkum DW (1995) Stem cell transplantation for severe autoimmune diseases: new proposals but still unanswered questions. Bone Marrow Transplant 16:497-498
37. Martini A, Maccario R, Ravelli A, Montagna D, De Benedetti F, Bonetti F, Viola S, Zecca M, Perotti C, Locatelli F (1999) Marked and sustained improvement two years after autologous stem cell transplant in a girl with systemic sclerosis. Arthritis Rheum 42:807-811
38. Matzinger P (1994) Tolerance, danger, and the extended family. Annu Rev Immunol 12:991-1045
39. Mondino A, Khoruts A, Jenkis MK (1996) The anatomy of T-cell activation and tolerance. Proc Natl. Acad Sci USA 93:2245-2252
40. Nossal GJV (1995) Choices following antigen entry: antibody formation or immunologie tolerance? Annu Rev Immunol 13:1-27
41. Owen RD (1945) Immunogenetic consequences of vascular anastomoses between bovine twins. Science 102:400-401
42. Pauling L (1940) A theory of the structure and process of formation of antibodies. J Am Chem Soc 62:2643-2657
43. Peng SL, Hardin JA, Craft J (1997) Antinuclear antibodies. In: Kelley WN, Ruddy S, Harris ED, Sledge CB (eds) Textbook of rheumatology. W.B. Saunders, Philadelphia, pp 250-266
44. Rieux-Laucat F, Le Deist F, Hivroz C, Roberts IA, Debatim KM, Fischer A, De Villartay JP (1995) Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 268:1347-1349
45. Schiffenbauer J, Soos J, Johnson H (1998) The possible role of bacterial superantigens in the pathogenesis of autoimmune disorders. Immunol Today 19:117-120
46. Silverstein AM, Rose NR (1997) On the mystique of the immunological self. Immunol Rev 159:197-206
47. Strober W, Kelsall B, Marth T (1998) Oral tolerance. J Clin Immunol 18:1-30
48. Talmage DW (1957) Allergy and immunology. Annu Rev Med 8:239-256
49. Traub E (1939) Epidemiology of lymphocytic choriomeningitis virus in a mouse stock observed for four years. J Exp Med 69:801-817
50. Tyndall A, Gratwohl A (1997) Blood and marrow stem cell transplants in autoimmune diseases. Br J Rheumatol 36:390-392
51. Vanderlugt CJ, Miller SD (1996) Epitope spreading. Curr Opin Immunol 8:831-836
52. Varela FJ, Coutinho A (1991) Second generation immune networks. Immunol Today 12:159-166
53. Waldmann H, Cobbold S (1998) How do monoclonal antibodies induce tolerance? A role for infectious tolerance? Annu Rev Immunol 16:619-644
54. Weiner HL (1997) Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol Today 18:335-343
55. Wucherpfenning KW, Strominger JL (1995) Molecular mimicry in T-cell mediated autoimmunity: viral peptides activate human T-cell clones specific for myelin basic protein. Cell 80:695-705
56. Wulffraat NW, Royen A van, Bierings M, Vossen JM, Kuis W (1999) Autologous haemopoietic stem cell transplantation in 4 cases with refractory juvenile chronic arthritis. Lancet 353:550-553
57. Zinkernagel RM, Doherty PC (1975) H-2 compatibility requirements for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. J Exp Med 141:1427-1436
58. Zinkernagel RF, Ehl S, Aichele P, Oehen S, Kundig T, Hengartner H (1997) Antigen localisation regulates immune response in a dose-and time-dependent fashion: a geographical view of immune reactivity. Immunol Rev 156:199-209