Alterations of p73 preferentially occur in gastric adenocarcinomas with foveolar epithelial phenotype

International Journal of Cancer

Volumn 83, Issue 2, 1999, Pages 192-196

  Yokozaki, Hiroshi ^a   Shitara, Yoshinori ^a   Fujimoto, Jyun Ya ^a   Hiyama, Toru ^a   Yasui, Wataru ^a   Tahara, Eiichi ^a  

^a HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE MUTATION; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE STRAND CONFORMATION POLYMORPHISM; STOMACH BIOPSY; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; TUMOR SUPPRESSOR GENE;

ADENOCARCINOMA; AGED; ALLELES; DNA MUTATIONAL ANALYSIS; DNA-BINDING PROTEINS; EPITHELIUM; FEMALE; GENES, TUMOR SUPPRESSOR; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PHENOTYPE; STOMACH NEOPLASMS; TUMOR SUPPRESSOR PROTEINS;

EID: 0032859474     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19991008)83:2<192::AID-IJC8>3.0.CO;2-E     Document Type: Article

References (36)

1. BELTINGER, C.P., WHITE, P.S., MARIS, J.M., SULMAN, E.P., JENSEN, S.J., LEPASLIER, D., STALLARD, B.J., GOEDDEL, D.V., DE SAUVAGE, F.J. and BRODEUR, G.M., Physical mapping and genomic structure of the human TNFR2 gene. Genomics, 35, 94-100 (1996).
2. BRODEUR, G.M., SEKHON, G. and GOLDSTEIN, M.N., Chromosomal aberrations in human neuroblastomas. Cancer, 40, 2256-2263 (1997).
3. DEED, R.W., HIROSE, T., MITCHELL, E.L.D., SANTIBANEZ-KOREF, M.F. and NORTON, J.D., Structural organisation and chromosomal mapping of the human Id-3 gene. Gene, 151, 309-314 (1994).
4. ENOMOTO, H., OZAKI, T., TAKAHASHI, E., NOMURA, N., TABATA, S., TAKAHASHI, H., OHNUMA, N., TANABE, M., IWAI, J., YOSHIDA, H., MATSUNAGA, T. and SAKIYAMA, S., Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus. Oncogene, 9, 2785-2791 (1994).
5. EZAKI. T., YANAGISAWA, A., OHTA, K., AISO, S., WATANABE, M., HIBI, T., KATO, Y., NAKAJIMA, T., ARIYAMA, T., INAZAWA, J., NAKAMURA, Y. and HORII, A., Deletion mapping on chromosome lp in well-differentiated gastric cancer. Brit. J. Cancer, 73, 424-428 (1996).
6. Kipl is haplo-insufficient for tumor suppression. Nature (Lond.), 396, 177-180 (1998).
7. FUJII, K., YOKOZAKI, H., YASUI, W., KUNIYASU, H., HIRATA, M., KAJIYAMA, G. and TAHARA, E., High frequency of p53 gene mutation in adenocarcinomas of the gallbladder. Cancer Epidemiol. Biomarkers Prevent., 5, 461-466 (1996)
8. GENUARDI, M., TSIHIRA, H., ANDERSON, D.E. and SAUNDERS, G.F. Distal deletion of chromosome 1p in ductal carcinoma of the breast. Amer. J. hum. Genet., 45, 73-82 (1989).
9. HATTORI, T., Morphological range of hyperplastic polyps and carcinomas arising in hyperplastic polyps of the stomach. J. clin. Pathol., 38, 622-630 (1985).
10. HIYAMA, T., YOKOZAKI, H., SHIMAMOTO, F., HARUMA, K., YASUI, W., KAJIYAMA, G. and TAHARA, E., Frequent p53 gene mutations in serrated adenomas of the colorectum. J. Pathol., 186, 131-139 (1998).
11. JAPANESE RESEARCH SOCIETY FOR GASTRIC CANCER (JRSGC), Japanese classification of gastric carcinoma (2nd English ed.). Gastric Cancer, 1, 10-24 (1998).
12. JOST, C.A., MARIN, M.C. and KAELIN, W.G., JR., p73 is a human p53-related protein that can induce apoptosis. Nature (Lond), 7, 191-194 (1997).
13. KAGHAD, M. AND 12 OTHERS, Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell, 90, 809-819 (1997).
14. KOIZUMI, Y. AND 13 OTHERS, Changes in DNA copy number in primary gastric carcinomas by comparative genomic hybridization. Clin. Cancer Res., 3, 1067-1076 (1997).
15. KUNIYASU, H., YASUI, W., YOKOZAKI, H., AKAGI, M., AKAMA, Y., KITAHARA, K., FUJII, K. and TAHARA, E., Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas. Int. J. Cancer, 59, 597-600 (1994).
16. KUSHIMA, R. and HATTORI, T., Histogenesis and characteristics of gastrictype adenocarcinomas in the stomach. J. Cancer Res. clin. Oncol., 120, 102-111 (1993).
17. KUSHIMA, R., MÜLLER, W., STOLTE, M. and BORCHARD, F., Differential p53 protein expression in stomach adenoma of gastric and intestinal pheno-types: possible sequences of p53 alteration in stomach carcinogenesis. Virchows Arch., 428, 223-227 (1996).
18. LAHTI, J.M., VALENTINE, M., XIANG, J., JONES, B., AMANN, J., GRENET, J., RICHMOND, G., LOOK, A.T. and KIDD, V.J., Alterations in the PITSLRE protein kinase gene complex on chromosome 1p36 in childhood neuroblastoma. Nature (Genet.), 7, 370-375 (1994).
19. LEFEBVRE, O., CHENARD, M.P., MASSON, R., LINARES, J., DIERICH, A., LEMEUR, M., WENDLING, C., TOMASETTO, C., CHAMBON, P. and RIO, M.C., Gastric mucosa abnormalities and tumorigenesis in mice lacking pS2 trefoil protein. Science, 274, 259-262 (1996).
20. MAI, M., YOKOMIZO, A., QUIAN, C., YANG, P., TINDALL, D.J., SMITH, D.I. and LIU, W., Activation of p73 silent allele in lung cancer. Cancer Res., 58, 2347-2349 (1998).
21. NAKAHARA, M., YOKOZAKI, H., YASUI, W., DOHI, K. and TAHARA, E., Identification of concurrent germ-line mutations in hMSH2 and/or hMLH1 in Japanese hereditary nonpolyposis colorectal cancer kindreds. Cancer Epidemiol. Biomarkers Prevent., 6, 1057-1064 (1997).
22. NIMURA, Y. AND 12 OTHERS, p73, a gene related to p53, is not mutated in esophageal carcinomas. Int. J. Cancer, 78, 437-440 (1998).
23. NOMOTO, S., HARUKI, N., KONDO, M., KONISHI, H., TAKAHASHI, T., TAKAHASHI, T. and TAKAHASHI, T., Search for mutations and examination of allelic expression imbalance of the p73 gene at 1p36.33 in human lung cancers. Cancer Res., 58, 1380-1283 (1998).
24. SANO, T., TSUJINO, T., YOSHIDA, K., NAKAYAMA, H., HARUMA, K., ITO, H., NAKAMURA, Y., KAJIYAMA, G. and TAHARA, E., Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas. Cancer Res., 51, 2926-2931 (1991).
25. SUNAHARA, M., ICHIMIYA, S., NIMURA, Y., TAKADA, N., SAKIYAMA, S., SATO, Y., TODO, S., ADACHI, W., AMANO, J. and NAKAGAWARA, A., Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas. Int. J. Oncol., 13, 319-323 (1998).
26. TAHARA, E., SEMBA, S. and TAHARA, H., Molecular biological observations in gastric cancer. Semin. Oncol., 23, 307-315 (1996).
27. TAKAHASHI, H., ICHIMIYA, M., NIMURA, Y., WATANABE, M., FURUSATO, M., WAKUI, S., YATANI, R., AIZAWA, S. and NAKAGAWARA, A., Mutation, allelotyping, and transcription analyses of the p73 gene in prostatic carcinoma. Cancer Res., 58, 2076-2077 (1998).
28. THEISINGER, B., WELTER, C., SEITZ, G., RIO, M.C., LATHE, R., CHAMBON, P. and BLIN, N., Expression of the breast cancer associated gene pS2 and the pancreatic spasmolytic polypeptide gene (hSP) in diffuse type stomach carcinoma. Europ. J. Cancer, 27A, 770-773 (1991).
29. TOHDO, H., YOKOZAKI, H., HARUMA, K., KAJIYAMA, G. and TAHARA, E., p53 gene mutations in gastric adenomas. Virchows Arch. B (Cell. Pathol.), 63, 191-195 (1993).
30. UCHINO, S., NOGUCHI, M., OCHIAI, A., SAITO, T., KOBAYASHI, M. and HIROHASHI, S., p53 mutation in gastric cancer: a genetic model for carcinogenesis is common to gastric and colorectal cancer. Int. J. Cancer, 54, 759-764 (1993).
31. VENKATACHALAM, S., SHI, Y.-P., JONES, S.N., VOGEL, H., BRADLEY, A., KINKEL, D. and DONEHOWER, L.A., Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation. EMBO J., 17, 4657-4667 (1998).
32. WHITE, P.S. AND 14 OTHERS, A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3. Proc. nat. Acad. Sci. (Wash.), 92, 5520-5524 (1995).
33. WONG, Z., WILSON, V., PATEL, I., POVEY, S. and JEFFREYS, A.J., Characterization of a panel of highly variable minisatellites cloned from human DNA. Ann. hum. Genet., 51, 269-288 (1987).
34. WU, M.-S., SHUN, C-T., WANG, H.-P., LEE, W.-J., WANG, T-H. and LIN, J.-T., Loss of pS2 protein expression is an early event of intestinal-type gastric cancer. Jpn. J. Cancer Res., 89, 278-282 (1998).
35. YOKOZAKI, H., KUNIYASU, H., KITADAI, Y., NISHIMURA, K., TODO, H., AYHAN, A., YASUI, W., ITO, H. and TAHARA, E., p53 point mutations in primary human gastric carcinomas. J. Cancer Res. clin. Oncol., 119, 67-70 (1992).
36. YOKOZAKI, H., KUNIYASU, H., SEMBA, S., YASUI, W. and TAHARA, E., Molecular bases of human stomach carcinogenesis. In: E. Tahara (ed.), Molecular pathology of gastroenterological cancer. Application to cinical practice, pp. 55-70, Springer-Verlag, Tokyo (1997).