Synthesis and in vitro antiprotozoal activity of thiophene ring- containing quinones

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 9, 1999, Pages 1221-1226

  Valderrama, Jaime ^a   Fournet, Alain ^b   Valderrama, Claudio ^a   Bastias, Sandra ^a   Astudillo, Claudio ^a   Rojas De Arias, Antonieta ^c   Inchausti, Alba ^c   Yaluff, Gloria ^c  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b Inst de Recherche sur les Vaccins   (France)

^c Instituto de Investigaciones en Ciencias de la Salud Universidad Nacional de Asuncion   (Paraguay)

Author keywords

Benzo b thiophene 4,7 quinones; Biological activity; Electron affinity; Leishmania; Synthesis; Trypanosoma cruzi

Indexed keywords

1,8 BIS (4,7 DIOXO 4,7 DIHYDROBENZO[B]THIOPHENE 2 CARBONYLOXY) 3,6 DIOXAOCTANE; 2 METHOXYCARBONYL 5 DIMETHYLAMINOBENZO[B]THIOPHENE 4,7 QUINONE; 3,6 DIMETHYL 2 METHOXYCARBONYLTHIENO[3,2 G]QUINOLINE 4,9 QUINONE; 5 METHYLTHIENO[2,3 G]QUINOLINE 4,9 QUINONE; 6 METHYLNAPHTHO[B]THIOPHENE 4,9 QUINONE; 7 METHYLNAPHTHO[B]THIOPHENE 4,9 QUINONE; ANTIPROTOZOAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIPROTOZOAL ACTIVITY; ARTICLE; DRUG CONFORMATION; DRUG EFFECT; DRUG SYNTHESIS; ELECTRIC POTENTIAL; LEISHMANIA; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA CRUZI;

EID: 0032848897     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1221     Document Type: Article

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