Mechanism for dexamethasone inhibition of neutrophil migration upon exposure to lipopolysaccharide in vitro: Role of neutrophil interleukin-8 release

Pediatric Research

Volumn 46, Issue 4, 1999, Pages 406-410

  Zentay, Zoltan ^a   Sharaf, Mohamed ^a   Qadir, Maqbool ^a   Drafta, Denise ^a   Davidson, Dennis ^a  

^a SCHNEIDER CHILDREN'S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE ANTIBODY; DEXAMETHASONE; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; STEROID;

ADULT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; LEUKOCYTE MIGRATION; LUNG DYSPLASIA; NEUTROPHIL; NEWBORN; PRIORITY JOURNAL; STEROID THERAPY;

EID: 0032848083     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-199910000-00008     Document Type: Article

References (35)

1. Yeh TF, Lin YJ, Hsieh WS, Lin HC, Lin CH, Chen JY, Kao HA, Chien CH 1997 Early postnatal dexamethasone therapy for the prevention of chronic lung disease in preterm infants with respiratory distress syndrome: a multicenter clinical trial Pediatrics 100:715-716
2. Papile LA, Tyson JE, Stoll BJ, Wright LL, Donovan EF, Bauer CR, Krause-Steinrauf H, Verter J, Korones SB, Lemons JA, Fanaroff AA, Stevenson DK 1998 A multicenter trial of two dexamethasone regimens in ventilator-dependent premature infants. N Engl J Med 338:1112-1118
3. Merritt TA, Cochrane CG, Holcomb K, Bohl B, Hallman M, Strayer D, Edwards DK 1983 Elastase and alpha 1-proteinase inhibitor activity in tracheal aspirates during respiratory distress syndrome. Role of inflammation in the pathogenesis of bronchopulmonary dysplasia. J Clin Invest 72:656-666
4. Kotecha S, Chan B, Azam N, Silverman M, Shaw RJ 1995 Increase in interleukin-8 and soluble intercellular adhesion molecule-1 in bronchoalveolar lavage fluid from premature infants who develop chronic lung disease Arch Dis Child 72:F90-F96
5. Groneck P, Götze-Speer B, Oppermann M, Eiffert H, Speer CP 1994 Association of pulmonary inflammation and increased microvascular permeability during the development of bronchopulmonary dysplasia: a sequential analysis of inflammatory mediators in respiratory fluids of high-risk preterm neonates. Pediatrics 93:712-718
6. Groneck P, Reuss D, Götze-Speer B, Speer CP 1993 Effects of dexamethasone on chemotactic activity and inflammatory mediators in tracheobronchial aspirates of preterm infants at risk for chronic lung disease. J Pediatr 122:938-944
7. Shinwell ES, Karplus M, Zmora E, Reich D, Rothschild A, Blazer S, Bader D, Yurman S, Dolfin T, Kuint J, Milbauer B, Kohelet D, Goldberg M, Armon Y, Davidson S, Sirota L, Amitai M, Zaretsky A, Barak M, Gottfried S 1996 Failure of early postnatal dexamethasone to prevent chronic lung disease in infants with respiratory distress syndrome. Arch Dis Child Fetal Neonat Educ 74:F33-F37
8. Root R 1997 The two-faced neutrophil-host defense versus tissue injury. In: Pratter HK, Nelson S (eds) Cytokines and Pulmonary Infection, Part I: Host Pathogen Interactions in Pulmonary Infections. American Thoracic Society, New York, pp 21-37
9. Stricter RM, Kasahara K, Allen RM, Standiford TJ, Rolfe MW, Becker FS, Chensue SW, Kunkel SL 1992 Cytokine-induced neutrophil-derived interleukin-8. Am J Pathol 141:397-407
10. McCain RW, Dessypris EN, Christman JW 1993 Granulocyte/macrophage colony-stimulating factor stimulates human polymorphonuclear leukocytes to produce interleukin-8 in vitro. Am J Respir Cell Mol Biol 8:28-34
11. Qadir M, Sharaf M, Drafta D, Davidson D 1997 Neutrophil-induced, neutrophil migration upon exposure to lipopolysaccharide in vitro: Interleukin 8 release is a dominant mechanism for the newborn. Pediatric Academic Societies Annual Meeting Washington, DC. Pediatr Res 41:218A
12. Boyum A 1976 Isolation of lymphocytes, granulocytes and macrophages. Scand. J Immunol 5(Suppl 5):9-15
13. Dos Santos C, Davidson D 1993 Neutrophil chemotaxis to leukotriene B4 in vitro is decreased for the human neonate. Pediatr Res 33:242-246
14. 4, and platelet-activating factor on neutrophil chemotaxis of the newborn. Pediatr Res 38:11-16
15. Lomas DA, Ip M, Chamba AA, Stockley RA 1991 The effect of in vitro and in vivo dexamethasone on human neutrophil function. Agents Actions 33:279-285
16. Cassatella MA, Bazzoni F, Ceska M, Ferro I, Baggiolini M, Berton G 1992 IL-8 production by human polymorphonuclear leukocytes. J Immunol 148:3216-3220
17. Barnes PJ, Karin M. 1997 Nuclear factor κ-β - a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071
18. Goodman RB, Stricter RM, Martin DP, Steinberg KP, Milberg JA, Maunder RJ, Kunkel SL, Walz A, Hudson LD, Martin TR 1996 Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med 154:602-611
19. Little S, Dean T, Bevin S, Hall M, Ashton M, Church M, Warner J, Shute J 1995 Role of elevated plasma soluble ICAM-1 and bronchial lavage fluid IL-8 levels as markers of chronic lung disease in premature infants. Thorax 50:1073-1079
20. Kunkel SL; Standiford T; Kasahara K; Stricter RM 1991 Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung. Exp Lung Res 17:17-23
21. Tiku K, Tiku ML, Skosey JL 1986 Interleukin-1 production by polymorphonuclear neutrophils. J Immunol 136:3677-3685
22. Dubravec DB, Spriggs DR, Mannick JA, Rodrick ML 1990 Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor. Proc Natl Acad Sci USA 87:6758-6761
23. Christman JW, Lancaster LH, Blackwell TS 1998 Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intens Care Med 24:1131-1138
24. Barnes PJ, Adcock 1993 Anti-inflammatory actions of steroids: molecular mechanisms. Trends Pharmacol Sci 14:436-441
25. Scheinman RI, Gualberto A, Jewel CM, Cidlowski JA, Baldwin AS 1995 Characterization of mechanisms involved in transrepression of NF-κβ by activated glucorticoid receptors. Mol Cell Biol 15:943-953
26. Tapia JL, Ramirez R, Cifuentes J, Fabres J, Hubner ME, Bancalari A, Mercado ME, Standen J; Escobar M 1998 The effect of early dexamethasone administration on bronchopulmonary dysplasia in preterm infants with respiratory distress syndrome. J Pediatr 132:48-52
27. Yeh TF, Torre JA, Rastogi A, Anyebuno MA, Pildes RS 1990 Early postnatal dexamethasone therapy in premature infants with severe respiratory distress syndrome: a double-blind, controlled study. J Pediatr 117:273-282
28. Sanders RJ, Cox C, Phelps DL, Sinkin RA 1994 Two doses of early intravenous dexamethasone for the prevention of bronchopulmonary dysplasia in babies with respiratory distress syndrome. Pediatr Res 36:122-128
29. Brozanski BS, Jones JG, Gilmour CH, Balsan MJ, Vazquez RL, Israel BA, Newman B, Mimouni FB, Guthrie RD 1995 Effect of pulse dexamethasone therapy on the incidence and severity of chronic lung disease in the very low birth weight infant. J Pediatr 126:769-776
30. Durand M, Sardesai S, McEvoy C 1995 Effects of early dexamethasone therapy on pulmonary mechanics and chronic lung disease in very low birth weight infants: a randomized, controlled trial. Pediatrics 95:584-590
31. Rastogi A, Akintorin SM, Bez ML, Morales P, Pildes RS 1996 A controlled trial of dexamethasone to prevent bronchopulmonary dysplasia in surfactant-treated infants. Pediatrics 98:204-210
32. Stoll BJ, Temprosa MG, Tyson JE, Papile LA, Wright LL, Donovan EF, Bauer CR, Verter JI 1998 Infections among very low birthweight infants enrolled in the NICHD Neonatal Research Network Dexamethasone (Dex) Trial. Pediatric Academic Societies Annual Meeting New Orleans, LA. Pediatr Res 43:253A
33. Schild PN, Charles BG 1994 Determination of dexamethasone in plasma of premature neonates using high-performance liquid chromatography. J Chromatogr B 658:189-192
34. McEvoy C, Mendoza ME, Bowling S, Durand M 1998 Low dose dexamethasone therapy in very low birth weight (VLBW) ventilator dependent infants (≤1250 g): A randomized trial. Pediatric Academic Societies Annual Meeting New Orleans, LA. Pediatr Res 43:184A
35. Watterberg KL, Gerdes JS, Gifford KL, Hung-MO L 1999 Prophylaxis against early adrenal insufficiency to prevent chronic lung disease in premature infants. Pediatric Academic Societies Annual Meeting San Francisco CA. Pediatr Res 45:232A