Failure of early postnatal dexamethasone to prevent chronic lung disease in infants with respiratory distress syndrome

Archives of Disease in Childhood

Volumn 74, Issue 1, 1996, Pages

  Shinwell, E S ^a   Karplus, M ^a   Zmora, E ^a   Reich, D ^b   Rothschild, A ^c   Blazer, S ^d   Bader, D ^e   Yurman, S ^f   Dolfin, T ^g   Kuint, J ^h   Milbauer, B ⁱ   Kohelet, D ^j   Goldberg, M ^k   Armon, Y ^l   Davidson, S ^m   Sirota, L ⁿ   Amitai, M ^o   Zaretsky, A ^p   Barak, M ^q   Gottfried, S ^r  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b HAEMEK MEDICAL CENTER   (Israel)

^c CARMEL MEDICAL CENTER   (Israel)

^d RAMBAM MEDICAL CENTER   (Israel)

^e BNAI ZION MEDICAL CENTER   (Israel)

^f HILLEL YAFFE MEDICAL CENTER   (Israel)

^g MEIR MEDICAL CENTER   (Israel)

^h SHEBA MEDICAL CENTER   (Israel)

ⁱ Hakirya Medical Center   (Israel)

^j WOLFSON MEDICAL CENTER   (Israel)

^k ASSAF HAROFEH MEDICAL CENTER   (Israel)

^l BIKUR CHOLIM HOSPITAL   (Israel)

^m RABIN MEDICAL CENTER   (Israel)

ⁿ Hasharon Medical Center   (Israel)

^o KAPLAN MEDICAL CENTER   (Israel)

^p BARZILAI MEDICAL CENTER   (Israel)

^q Nahariya Regional Medical Center   (Israel)

^r Rebecca Sieff Government Hospital   (Israel)

more..

Author keywords

Chronic lung disease; Respiratory distress syndrome; Steroids; Surfactant

Indexed keywords

DEXAMETHASONE; LUNG SURFACTANT; PLACEBO; SURFACTANT TA;

ARTICLE; ARTIFICIAL VENTILATION; CHRONIC LUNG DISEASE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NEWBORN; NEWBORN INTENSIVE CARE; PREMATURITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY DISTRESS SYNDROME;

BIRTH WEIGHT; CHRONIC DISEASE; DEXAMETHASONE; DOUBLE-BLIND METHOD; FEMALE; GLUCOCORTICOIDS; HUMANS; INFANT, NEWBORN; LUNG DISEASES; MALE; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, NEWBORN; TREATMENT FAILURE;

EID: 0030071806     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/fn.74.1.f33     Document Type: Article

References (21)

1. AAP Committee on the Fetus and Newborn. Surfactant replacement therapy for respiratory distress syndrome. Pediatrics 1991; 87: 946-7.
2. Fujiwara T, Konishi M, Chida S, Ogawa Y, Takeuchi Y. Surfactant replacement therapy with a single postventilatory dose of a reconstituted bovine surfactant in preterm infants with respiratory distress syndrome: Final analysis of a multicenter, double-blind, randomized trial and comparison with similar trials. Pediatrics 1990; 86: 753-64.
3. Soll RF, McQueen MC. Respiratory distress syndrome. In: Effective care of rhe newborn infant. Oxford: Oxford University Press, 1992: 325-58.
4. Avery U, Fletcher AB, Kaplan M, Brudno DS. Controlled trial of dexamethasone in respirator-dependent infants with bronchopulmonary dysplasia. Pediatrics 1985; 75: 106-11.
5. Cummings JJ, D'Eugenio DB, Gross SJ. A controlled trial of dexamethasone in preterrn infants at risk for bronchopulmonary dysplasia. N Engl J Med 1989; 320: 1505-10.
6. Harkavy KL, Scanlon JW, Chowdhry PK, Grylack LJ. Dexamethasone therapy for chronic lung disease in ventilator- and oxygen-dependent infants: A controlled trial. J Pediatr 1989; 115: 979-83.
7. Collaborative Dexamethasone Trial Group. Dexamethasone therapy in neonatal chronic lung disease: An international, placebo-controlled trial. Pediatrics 1991; 88: 421-7.
8. Merritt TA, Stuard ID, Puccia J, Wood B, Edwards DK, Finkelstein J, et al. Newborn tracheal aspirate cytology: classification during respiratory distress syndrome and bronchopulmonary dysplasia. J Pediatr 1981; 98: 949-56.
9. Ogden H, Murphy S, Saunders G, Pathak D, Johnson J. Neonatal lung neutrophils and elastase/proteinase inhibitor imbalance. Am Rev Respir Dis 1984; 130: 817-21.
10. McColm J, McIntosh N. Tracheal IL8 as a predictor of chronic lung disease. Ped Res 1994; 36: A153.
11. Groneck P, Opperman M, Speer CP. Levels of complement anaphylatoxin C5a in pulmonary effluent fluid of infants at risk for chronic lung disease and effects of dexamethasone treatment. Ped Res 1993; 34: 586-90.
12. Groneck P, Reuss D, Goetze-Speer B, Speer CP. Effects of dexamethasone on chemotactic activity and inflammatory mediators in tracheobronchial aspirates of preterm infants at risk for chronic lung disease. J Pediatr 1993; 122; 938-44.
13. Yeh TF, Torre JA, Rastogi A, Anyebuno MA, Pildes RS. Early postnatal dexamethasone therapy in premature infants with severe respiratory distress syndrome: A double-blind, controlled study. J Pediatr 1990; 117: 273-82.
14. Baden M, Bauer CR, Colle E, Klein G, Taeusch HW, Stern L. A controlled trial of hydrocortisone therapy in infants with respiratory distress syndrome. Pediatrics 1972; 50: 526-34.
15. Sanders RJ, Cox C, Phelps DL, Sinkin RA. Two doses of early intravenous dexamethasone for the prevention of bronchopulmonary dysplasia in babies with respiratory distress syndrome. Ped Res 1994; 36: 122-8.
16. Yeh TF, Lin IJ, Shieh WS, Lin HC, Lin CH, Chen JY, et al. Prevention of chronic lung disease in premature RDS infants with early and prolonged dexamethasone therapy - a multicenter, double-blind controlled study. Ped Res 1994; 36; 262A.
17. Rastogi A, Morales P, Akintorin S, Bez M, David R, Pildes RS. Randomized, double-blind trial of dexamethasone plus surfactant for prevention of bronchopulmonary dysplasia. Ped Res 1994; 36: 1486A.
18. Giedion A, Haefliger H, Dangel P. Acute pulmonary x-ray changes in hyaline membrane disease treated with artificial ventilation and positive end-expiratory pressure. Pediatr Radiol 1973; 1: 145-52.
19. Levene MI. Measurement of the growth of the lateral ventricles in preterm infants with real-time ultrasound. Arch Dis Child 1981; 56: 900-4.
20. Committee for the classification of ROP. An international classification of retinopathy of prematurity. Pediatrics 1984; 74: 127-33.
21. van Houten J, Long W, Mullett M, Finer N, Derleth D, McMurray B, et al. Pulmonary hemorrhage in premature infants after treatment with synthetic surfactant: an autopsy evaluation. J Pediatr 1992; 120: S40-4.