Functional promoter polymorphism of the human serotonin transporter: Lack of association with panic disorder

Psychiatric Genetics

Volumn 7, Issue 1, 1997, Pages 45-47

  Deckert, J ^a   Catalano, M ^b   Heils, A ^a   Di Bella, D ^b   Friess, F ^a   Politi, E ^b   Franke, P ^c   Nothen M M ^c   Maier, W ^c   Bellodi, L ^b   Lesch, K P ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b DSNP   (Italy)

^c UNIVERSITY OF BONN   (Germany)

Author keywords

Panic disorder; Promoter variant; Serotonin transporter

Indexed keywords

SEROTONIN; TRANSCRIPTION FACTOR;

ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE FREQUENCY; GENE MUTATION; GERMANY; HUMAN; MAJOR CLINICAL STUDY; PANIC; PRIORITY JOURNAL; PROMOTER REGION;

EID: 8544260300     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041444-199700710-00008     Document Type: Article

References (16)

1. American Psychiatrie Association (1987) Diagnostic and Statistical Manual of Mental Disorders. Third Edition, Revised. American Psychiatric Association, Washington, DC.
2. Battaglia M, Bertella S, Politi E, Bernardeschi L, Perna G, Gabriele A and Bellodi L (1995) Age at onset of panic disorder: influence of familial liability to the disease and of childhood separation anxiety disorder. American Journal of Psychiatry, 152, 1362-1364.
3. Chopin P and Briley M (1987) Animal models of anxiety: The effect of compounds that modify 5-HT neurotransmission. Trends in Pharmacological Sciences, 8, 383-388.
4. Crowe RR, Noyes R, Pauls DL and Slymen D (1983) A family study of panic disorder. Archives of General Psychiatry, 40, 1065-1069.
5. Heils A, Teufel A, Petri S, Seemann M, Bengel D, Balling U, Riederer P and Lesch KP (1995) Functional promoter and polyadenylation site mapping of the human serotonin (5-HT) transporter gene. Journal of Neural Transmission, 102, 247-254.
6. Heils A, Teufel A, Petri S, Stöber G, Riederer P, Bengel D and Lesen KP (1996) Allelic variation of human serotonin transporter gene expression. Journal of Neurochemistry, 66, 2621-2624.
7. Iny LJ, Pecknold J, Suranyi-Cadotte BE, Bernier B, Luthe L, Nair NPV and Meaney MJ (1994) Studies of a neurochemical link between depression, anxiety, and stress from (3H) imipramine and (3H) paroxetine binding on human platelets. Biological Psychiatry, 36, 281-291.
8. Kahn RS and Wetzler S (1991) m-Chlorophenylpiperazine as a probe of serotonin function. Biological Psychiatry, 30, 1139-1166.
9. Lahiri DK and Nurnberger JI (1991) A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Research, 19, 5444.
10. Losch KP, Wolozin BL, Estler HC, Murphy DL and Riederer P (1993) Isolation of a cDNA encoding the human brain serotonin transporter. Journal of Neural Transmission, 91, 67-73.
11. Losch KP, Balling U, Gross J, Strauss K, Wolozin BL, Murphy DL and Riederer P (1994) Organization of the human serotonin transporter gene. Journal of Neural Transmission, 95, 157-164.
12. Maier W, Lichtermann D, Minges J, Oehrlein A and Franke P (1993) A controlled family study in panic disorder, Journal of Psychiatric Research, 27 (Suppl 1), 79-87.
13. Miller SA, Dykes DD and Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Research, 16, 1215.
14. Ramamoorthy S, Baumann A, Moore K, Han H, Yang-Feng T, Chang A, Ganapathy V and Blakely R (1993) Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization. Proceedings of the National Academy of Sciences USA, 90, 2542-2546.
15. Robins L and Regier DA (1991) Psychiatric Disorder in America. Free Press, New York.
16. Torgersen S (1983) Genetic factors in anxiety disorders. Archives of General Psychiatry, 40, 1085-1089.