Evaluation of the staphylococcal exotoxins and their specific IgE in childhood atopic dermatitis

Journal of Allergy and Clinical Immunology

Volumn 104, Issue 2 I, 1999, Pages 441-446

  Nomura, Ichiro ^a   Tanaka, Kazuko ^b   Tomita, Hisashi ^b   Katsunuma, Toshio ^a   Ohya, Yukihiro ^a   Ikeda, Norikazu ^b   Takeda, Tae ^b   Saito, Hirohisa ^b   Akasawa, Akira ^a  

^a NATIONAL CHILDREN S HOSPITAL   (Japan)

^b NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Atopic dermatitis; Leicester's disease activity score; Specific IgE; Staphylococcal exotoxin

Indexed keywords

IMMUNOGLOBULIN E; STAPHYLOCOCCUS TOXIN;

ADOLESCENT; ADULT; AGE; ANTIBODY TITER; ARTICLE; ATOPIC DERMATITIS; BACTERIUM ISOLATION; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SCORING SYSTEM; STAPHYLOCOCCUS AUREUS;

EID: 0032828538     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(99)70390-8     Document Type: Article

References (15)

1. Leung DY. Atopic dermatitis: the skin as a window into the pathogenesis of chronic allergic diseases. J Allergy Clin Immunol 1995;96:302-18.
2. Motala C, Potter PC, Weinberg EG, Malherbe D, Hughes J. Anti-Staphylococcus aureus-specific IgE in atopic dermatitis. J Allergy Clin Immunol 1986;78:583-9
3. Marrack P, Kappler J. The staphylococcal enterotoxins and their relatives. Science 1990;248:705-1.
4. Neuber K, Steinrucke K, Ring J. Staphylococcal enterotoxin B affects in vitro IgE synthesis, interferon-γ, interleukin-4 and interleukin-5 production in atopic eczema. Int Arch Allergy Immunol 1995;107:179-82.
5. Hofer MF, Lester MR, Schlievert PM, Leung DY. Upregulation of IgE synthesis by staphylococcal toxic shock syndrome toxin-1 in peripheral blood mononuclear cells from patients with atopic dermatitis. Clin Exp Allergy 1995;25:1218-27.
6. Jabara HH, Geha RS. The superantigen toxic shock syndrome toxin-1 induces CD40 ligand expression and modulates IgE isotype switching. Int Immunol 1996;8:1503-10.
7. Leung DY, Gately M, Trumble A, Ferguson DB, Schlievert PM, Picker LJ. Bacterial superantigens induce T cell expression of the skin-selective homing receptor, the cutaneous lymphocyte-associated antigen, via stimulation of interleukin 12 production. J Exp Med 1995;181:747-53.
8. Saloga J, Leung DY, Reardon C, Giorno RC, Born W, Gelfand EW. Cutaneous exposure to the superantigen staphylococcal enterotoxin B elicits a T-cell-dependent inflammatory response. J Invest Dermatol 1996;106:982-8.
9. Akiyama H, Toi Y, Kanzaki H, Tada J, Arata J. Prevalence of producers of enterotoxins and toxic shock syndrome toxin-1 among Staphylococcus aureus strains isolated from atopic dermatitis lesions. Arch Dermatol Res 1996;288:418-20.
10. Leung DY, Harbeck R, Bina P, Reiser RF, Yang E, Norris DA, et al. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 1993;92:1374-80.
11. Tada J, Toi Y, Akiyama H, Arata J, Kato H. Presence of specific IgE antibodies to staphylococcal enterotoxins in patients with atopic dermatitis. Eur J Dermatol 1996;6:552-4.
12. Nissen D, Pedersen LJ, Skov PS, Vejlsgaard GL, Poulsen LK, Jarlov JO, et al. IgE-binding components of staphylococcal enterotoxins in patients with atopic dermatitis. Ann Allergy Asthma Immunol 1997;79:403-8.
13. Bunikowski R, Mielke M, Skarabis H, Herz U, Bergmann RL, Wahn U, et al. Prevalence and role of serum IgE antibodies to the Staphylococcus aureus-derived superantigens SEA and SEB in children with atopic dermatitis. J Allergy Clin Immunol 1999;103:119-24.
14. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol 1980;9:44-7.
15. Sowden JM, Berth JJ, Ross JS, Motley RJ, Marks R, Finlay AY, et al. Double-blind, controlled, crossover study of cyclosporin in adults with severe refractory atopic dermatitis. Lancet 1991;338:137-40.