Zinc inhibition of γ-aminobutyric acid(A) receptor function is decreased in the cerebral cortex during pilocarpine-induced status epilepticus

Journal of Pharmacology and Experimental Therapeutics

Volumn 291, Issue 1, 1999, Pages 361-366

  Banerjee, Pradeep K ^a   Olsen, Richard W ^a   Snead III, O Carter ^b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; ALFAXALONE; CHLORINE 36; DIAZEPAM; FLUNITRAZEPAM; MUSCIMOL; PENTOBARBITAL; PILOCARPINE; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CEREBELLUM; CHLORIDE TRANSPORT; CONTROLLED STUDY; DRUG INHIBITION; EPILEPTIC STATE; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BIOLOGICAL TRANSPORT; CEREBELLUM; CEREBRAL CORTEX; CHLORIDES; GABA AGONISTS; MALE; MUSCARINIC AGONISTS; MUSCIMOL; PILOCARPINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; STATUS EPILEPTICUS; ZINC;

EID: 0032825881     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. 2+ from brain tissue during activity. Nature (Lond) 308:734-736.
2. 3H]flunitrazepam binding in the hippocampus following status epilepticus. Soc Neurosci Abstr 24:1936.
3. 35S]butylbicyclophosphorothionate binding in thalamic relay nuclei. J Pharmacol Exp Ther 287:766-772.
4. A receptor α1 and α4 subunit mRNA levels in thalamic relay nuclei following absence seizures. Exp Neurol 164:213-223.
5. A receptor-operated chloride channels: I. Acute effects of ethanol. J Pharmacol Exp Ther 253:706-712.
6. Buhl EH, Otis TS and Mody I (1996) Zinc-induced collapse of augmented inhibition by GABA in a temporal lobe epilepsy model. Science (Wash DC) 271:369-373.
7. Cavalheiro EA, Leite JP, Bortolotto ZA, Turski WA, Ikonomidou C and Turski L (1991) Long term effects of pilocarpine in rats: Structural damage of brain triggers kindling and spontaneous recurrent seizures. Epilepsia 32:778-782.
8. Cavazos JE, Golarai G and Sutula TP (1991) Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permeance. J Neurosci 11:2795-2803.
9. Chen LS, Wong JG, Banerjee PK and Snead OC (1996) Kainic acid-induced focal cortical seizures is associated with an increase of synaptophysin immunoreactivity in the cortex. Exp Neural 141:25-31.
10. Choi DW and Koh JY (1998) Zinc and brain injury. Annu Rev Neurosci 21:347-375.
11. Choi DW, Yokoyama M and Koh JY (1988) Zinc neurotoxicity in cortical cell culture. Neuroscience 24:67-79.
12. Dube C, Andre V, Covolan L, Ferrandon A, Marescaux C and Nehlig A (1998) C-Fos, Jun D and HSP72 immunoreactivity, and neuronal injury following lithium-pilocarpine induced status epilepticus in immature and adult rats. Mol Brain Res 63:139-154.
13. Fredrickson CJ, Hernandez MD and McGinty JF (1989) Translocation of zinc may contribute to seizure-induced death of neurons. Brain Res 480:317-321.
14. Fujikawa DG (1996) The temporal evolution of neuronal damage from pilocarpine-induced status epilepticus. Brain Res 725:11-22.
15. A receptor function in dentate granule and CA1 neurons. J Neurophysiol 77:1924-1938.
16. Harris RA and Allan AM (1985) Functional coupling of GABA receptors to chloride channels in brain membranes. Science (Wash DC) 228:1108-1110.
17. Howell GA, Welch MG and Fredrickson CJ (1984) Stimulation-induced uptake and release of zinc in hippocampal slices. Nature (Lond) 308:736-738.
18. A receptor function in CA1 pyramidal neurons. Ann Neurol 38:893-900.
19. A receptors during partial status epilepticus. Neurology 44:2407-2408.
20. A receptor. J Neurosci 17:7532-7540.
21. Koh JY, Suh SW, Gwag BJ, He YY, Hsu CY and Choi DW (1996) The role of zinc in selective neuronal death after transient global cerebral ischemia. Science (Wash DC) 272:1013-1016.
22. A channels by zinc. Mol Pharmacol 39:267-274.
23. Lemos T and Cavalheiro EA (1995) Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats. Exp Brain Res 102:423-428.
24. A receptor channels. Annu Rev Neurosci 17:569-602.
25. Mody I and Miller JJ (1985) Levels of hippocampal calcium and zinc following kindling-induced epilepsy. Can J Physiol Pharmacol 63:159-161.
26. Motte J, Fernandes MJS, Baram TZ and Nehlig A (1998) Spatial and temporal evolution of neuronal activation, stress and injury in lithium-pilocarpine seizures in adult rats. Brain Res 793:61-72.
27. 2 pretreatment on behavioral and histological responses to kainic acid in rats. Brain Res 604:298-303.
28. Pei YQ and Koyama I (1986) Features of seizures and behavioral changes induced by intrahippocampal injection of zinc sulfate in the rabbit: A new experimental model of epilepsy. Epilepsia 27:183-188.
29. Peterson GL (1977) A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 83:346-356.
30. A benzodiazepine receptors produced in transfected cells. Science (Wash DC) 245: 1389-1391.
31. Pritchett DB, Sontheimer H, Shivers B, Ymer S, Kettenmann H, Schofield PR and Seeburg, PH (1989a) Importance of a novel GABAA receptor subunit for benzodiazepine pharmacology. Nature (Lond) 338:582-585.
32. Ramsey RE (1993) Treatment of status epilepticus. Epilepsia 34(Suppl 1): S71-S81.
33. Shin C, Pedersen HB and McNamara JO (1985) γ-Aminobutyric acid and benzodiazeopine receptors in the kindling model of epilepsy: A quantitative radiohistochemical study. J Neurosci 5:2696-2701.
34. Smart TG, Xie X and Krishek BJ (1994) Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc. Prog Neurobiol 42:393-441.