Studies on sulfation of synthesized metabolites from the local anesthetics ropivacaine and lidocaine using human cloned sulfotransferases

Drug Metabolism and Disposition

Volumn 27, Issue 9, 1999, Pages 1057-1063

  Falany, Charles N ^a   Falany, Josie L ^a   Wang, Jin ^a   Hedström, Johan ^b   Von Euler Chelpin, Hans ^b   Swedmark, Stellan ^b  

^a University of Alabama at Birmingham   (United States)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

LIDOCAINE; ROPIVACAINE; SULFOTRANSFERASE;

ARTICLE; CHANNEL GATING; DEALKYLATION; DRUG METABOLISM; DRUG SULFATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROLYSIS; HYDROXYLATION; LIVER MICROSOME; LOCAL ANESTHESIA; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

AMIDES; ANESTHETICS, LOCAL; BIOTRANSFORMATION; CYTOSOL; HUMANS; HYDROXYLATION; ISOENZYMES; KINETICS; LIDOCAINE; MASS SPECTROMETRY; RECOMBINANT PROTEINS; SULFATES; SULFOTRANSFERASES;

EID: 0032822219     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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