메뉴 건너뛰기




Volumn 109, Issue 1-3, 1998, Pages 195-219

Sulfotransferase-mediated activation of mutagens studied using heterologous expression systems

Author keywords

Aromatic amines; Benzylic alcohols; Chinese hamster V79 cells; Hycanthone; Mutagenicity; Polycyclic aromatic hydrocarbons; Safrole; Salmonella typhimurium; Sulfotransferase; Tamoxifen

Indexed keywords

1' HYDROXYSAFROLE; BENZYL ALCOHOL DERIVATIVE; DNA; HYCANTHONE; HYDROXYTAMOXIFEN; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTAGENIC AGENT; N (2 FLUORENYL)ACETAMIDE; POLYCYCLIC AROMATIC HYDROCARBON; SAFROLE; SULFATE; SULFOTRANSFERASE; TIOGUANINE; UNCLASSIFIED DRUG;

EID: 0032549062     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(97)00133-6     Document Type: Conference Paper
Times cited : (78)

References (57)
  • 2
    • 0028301393 scopus 로고
    • Activation of promutagens by endogenous and heterologous sulfotransferases expressed in continuous cell cultures
    • Glatt H.R., Pauly K., Piée-Staffa A., Seidel A., Hornhardt S., Czich A. Activation of promutagens by endogenous and heterologous sulfotransferases expressed in continuous cell cultures. Toxicol. Lett. 72:1994;13-21.
    • (1994) Toxicol. Lett. , vol.72 , pp. 13-21
    • Glatt, H.R.1    Pauly, K.2    Piée-Staffa, A.3    Seidel, A.4    Hornhardt, S.5    Czich, A.6
  • 3
    • 0020044747 scopus 로고
    • A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[a]anthracene
    • Watabe T., Ishizuka T., Isobe M., Ozawa N. A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[a]anthracene. Science. 215:1982;403-405.
    • (1982) Science , vol.215 , pp. 403-405
    • Watabe, T.1    Ishizuka, T.2    Isobe, M.3    Ozawa, N.4
  • 5
    • 0001042792 scopus 로고
    • Synthesis of 11 benzylic sulfate esters, their bacterial mutagenicity and its modulation by chloride, bromide and acetate anions
    • Enders N., Seidel A., Monnerjahn S., Glatt H.R. Synthesis of 11 benzylic sulfate esters, their bacterial mutagenicity and its modulation by chloride, bromide and acetate anions. Polycyclic Aromat. Compds. 3(Suppl.):1993;887-894.
    • (1993) Polycyclic Aromat. Compds. , vol.3 , Issue.SUPPL. , pp. 887-894
    • Enders, N.1    Seidel, A.2    Monnerjahn, S.3    Glatt, H.R.4
  • 6
    • 0001483889 scopus 로고    scopus 로고
    • Physico-chemical properties and mutagenicity of benzylic compounds
    • Landsiedel R., Engst W., Seidel A., Glatt H.R. Physico-chemical properties and mutagenicity of benzylic compounds. Exp. Toxicol. Pathol. 48(Suppl. II):1996;215-222.
    • (1996) Exp. Toxicol. Pathol. , vol.48 , Issue.SUPPL. II , pp. 215-222
    • Landsiedel, R.1    Engst, W.2    Seidel, A.3    Glatt, H.R.4
  • 7
    • 0030355238 scopus 로고    scopus 로고
    • Benzylic sulphuric acid esters react with diverse functional groups and often form secondary reactive species
    • Landsiedel R., Engst W., Scholtyssek M., Seidel A., Glatt H.R. Benzylic sulphuric acid esters react with diverse functional groups and often form secondary reactive species. Polycyclic Aromat. Compds. 11:1996;341-348.
    • (1996) Polycyclic Aromat. Compds. , vol.11 , pp. 341-348
    • Landsiedel, R.1    Engst, W.2    Scholtyssek, M.3    Seidel, A.4    Glatt, H.R.5
  • 9
    • 0028981772 scopus 로고
    • Activation of benzylic alcohols to mutagens by rat and human sulfotransferases expressed in Escherichia coli
    • Glatt H.R., Pauly K., Czich A., Falany J.L., Falany C.N. Activation of benzylic alcohols to mutagens by rat and human sulfotransferases expressed in Escherichia coli. Eur. J. Pharmacol. 293:1995;123-131.
    • (1995) Eur. J. Pharmacol. , vol.293 , pp. 123-131
    • Glatt, H.R.1    Pauly, K.2    Czich, A.3    Falany, J.L.4    Falany, C.N.5
  • 10
    • 0029093466 scopus 로고
    • Bacterial expression and kinetic characterization of the human monoamine-sulfating form of phenol sulfotransferase
    • Ganguly T.C., Krasnykh V., Falany C.N. Bacterial expression and kinetic characterization of the human monoamine-sulfating form of phenol sulfotransferase. Drug Metab. Dispos. 23:1995;945-950.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 945-950
    • Ganguly, T.C.1    Krasnykh, V.2    Falany, C.N.3
  • 11
    • 0032549055 scopus 로고    scopus 로고
    • Heterologous expression of human estrogen sulfotransferase in Salmonella typhimurium and its use for mutagenicity studies
    • (this issue)
    • Hagen M., Pabel U., Bartsch I., Landsiedel R., Falany C.N., Glatt H.R. Heterologous expression of human estrogen sulfotransferase in Salmonella typhimurium and its use for mutagenicity studies. Chem. Biol. Interact. 109:1998;249-253. (this issue).
    • (1998) Chem. Biol. Interact. , vol.109 , pp. 249-253
    • Hagen, M.1    Pabel, U.2    Bartsch, I.3    Landsiedel, R.4    Falany, C.N.5    Glatt, H.R.6
  • 12
    • 0020510718 scopus 로고
    • + for all three chromosomally located systems of DNA restriction and modification
    • + for all three chromosomally located systems of DNA restriction and modification. J. Bacteriol. 156:1983;471-474.
    • (1983) J. Bacteriol. , vol.156 , pp. 471-474
    • Bullas, L.R.1    Ryu, J.-I.2
  • 13
    • 0023812877 scopus 로고
    • Vectors for efficient expression in mammalian fibroblastoid, myeloid and lymphoid cells via transfection or infection
    • Artelt P., Morelle C., Ausmeier M., Fitzek M., Hauser H. Vectors for efficient expression in mammalian fibroblastoid, myeloid and lymphoid cells via transfection or infection. Gene. 68:1988;213-219.
    • (1988) Gene , vol.68 , pp. 213-219
    • Artelt, P.1    Morelle, C.2    Ausmeier, M.3    Fitzek, M.4    Hauser, H.5
  • 14
    • 0028245971 scopus 로고
    • Stable heterologous expression of hydroxysteroid sulfotransferase in Chinese hamster V79 cells and their use for toxicological investigations
    • Czich A., Bartsch I., Dogra S., Hornhardt S., Glatt H.R. Stable heterologous expression of hydroxysteroid sulfotransferase in Chinese hamster V79 cells and their use for toxicological investigations. Chem.-Biol. Interact. 92:1994;119-128.
    • (1994) Chem.-Biol. Interact. , vol.92 , pp. 119-128
    • Czich, A.1    Bartsch, I.2    Dogra, S.3    Hornhardt, S.4    Glatt, H.R.5
  • 15
    • 0028286684 scopus 로고
    • Molecular cloning and functions of rat liver hydroxysteroid sulfotransferases catalysing covalent binding of carcinogenic polycyclic arylmethanols to DNA
    • Watabe T., Ogura K., Satsukawa M., Okuda H., Hiratsuka A. Molecular cloning and functions of rat liver hydroxysteroid sulfotransferases catalysing covalent binding of carcinogenic polycyclic arylmethanols to DNA. Chem.-Biol. Interact. 92:1994;87-105.
    • (1994) Chem.-Biol. Interact. , vol.92 , pp. 87-105
    • Watabe, T.1    Ogura, K.2    Satsukawa, M.3    Okuda, H.4    Hiratsuka, A.5
  • 16
    • 0027504348 scopus 로고
    • Isolation and expression of a cDNA encoding a male-specific rat sulfotransferase that catalyzes activation of N-hydroxy-2-acetylaminofluorene
    • Nagata K., Ozawa S., Miyata M., Shimada M., Gong D.W., Yamazoe Y., Kato R. Isolation and expression of a cDNA encoding a male-specific rat sulfotransferase that catalyzes activation of N-hydroxy-2-acetylaminofluorene. J. Biol. Chem. 268:1993;24720-24725.
    • (1993) J. Biol. Chem. , vol.268 , pp. 24720-24725
    • Nagata, K.1    Ozawa, S.2    Miyata, M.3    Shimada, M.4    Gong, D.W.5    Yamazoe, Y.6    Kato, R.7
  • 17
    • 0026349345 scopus 로고
    • Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17β-estradiol and 2-aminofluorene in V79 Chinese hamster cells
    • Wölfel C., Platt K.-L., Dogra S., Glatt H.R., Wächter F., Doehmer J. Stable expression of rat cytochrome P450IA2 cDNA and hydroxylation of 17β-estradiol and 2-aminofluorene in V79 Chinese hamster cells. Mol. Carcinog. 4:1991;489-498.
    • (1991) Mol. Carcinog. , vol.4 , pp. 489-498
    • Wölfel, C.1    Platt, K.-L.2    Dogra, S.3    Glatt, H.R.4    Wächter, F.5    Doehmer, J.6
  • 18
    • 0028898346 scopus 로고
    • Human platelet phenolsulfotransferases: CDNA cloning, stable expression in V79 cells and identification of a novel allelic variant of the phenol-sulfating form
    • Jones A.L., Hagen M., Coughtrie M.W.H., Roberts R.C., Glatt H.R. Human platelet phenolsulfotransferases: cDNA cloning, stable expression in V79 cells and identification of a novel allelic variant of the phenol-sulfating form. Biochem. Biophys. Res. Commun. 208:1995;855-862.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 855-862
    • Jones, A.L.1    Hagen, M.2    Coughtrie, M.W.H.3    Roberts, R.C.4    Glatt, H.R.5
  • 19
    • 0029051063 scopus 로고
    • Human fetal adrenal hydroxysteroid sulphotransferase: CDNA cloning, stable expression in V79 cells and functional characterization of the expressed enzyme
    • Forbes K.J., Hagen M., Glatt H.R., Hume R., Coughtrie M.W.H. Human fetal adrenal hydroxysteroid sulphotransferase: cDNA cloning, stable expression in V79 cells and functional characterization of the expressed enzyme. Mol. Cell. Endocrinol. 112:1995;53-60.
    • (1995) Mol. Cell. Endocrinol. , vol.112 , pp. 53-60
    • Forbes, K.J.1    Hagen, M.2    Glatt, H.R.3    Hume, R.4    Coughtrie, M.W.H.5
  • 20
    • 0027956942 scopus 로고
    • Comparison of common gene mutation tests in mammalian cells in culture: A position paper of the GUM Commission for the development of guidelines for genotoxicity testing
    • Glatt H.R. Comparison of common gene mutation tests in mammalian cells in culture: a position paper of the GUM Commission for the development of guidelines for genotoxicity testing. Mutat. Res. 313:1994;7-20.
    • (1994) Mutat. Res. , vol.313 , pp. 7-20
    • Glatt, H.R.1
  • 21
    • 0023402354 scopus 로고
    • Search for cell culture systems with diverse xenobiotic-metabolising activities and their use in toxicological studies
    • Glatt H.R., Gemperlein I., Turchi G., Heinritz H., Doehmer J., Oesch F. Search for cell culture systems with diverse xenobiotic-metabolising activities and their use in toxicological studies. Mol. Toxicol. 1:1987;313-333.
    • (1987) Mol. Toxicol. , vol.1 , pp. 313-333
    • Glatt, H.R.1    Gemperlein, I.2    Turchi, G.3    Heinritz, H.4    Doehmer, J.5    Oesch, F.6
  • 22
    • 0010629535 scopus 로고
    • Stable expression of heterologous cytochromes P450 in V79 cells: Mutagenicity studies with polycyclic aromatic hydrocarbons
    • Glatt H.R., Pauly K., Wölfel C., Dogra S., Seidel A., Lee H., Harvey R.G., Oesch F., Doehmer J. Stable expression of heterologous cytochromes P450 in V79 cells: mutagenicity studies with polycyclic aromatic hydrocarbons. Polycyclic Aromat. Compds. 3(Suppl. ):1993;1167-1174.
    • (1993) Polycyclic Aromat. Compds. , vol.3 , Issue.SUPPL. , pp. 1167-1174
    • Glatt, H.R.1    Pauly, K.2    Wölfel, C.3    Dogra, S.4    Seidel, A.5    Lee, H.6    Harvey, R.G.7    Oesch, F.8    Doehmer, J.9
  • 23
    • 0027359552 scopus 로고
    • Some substrates and inhibitors of cytosolic epoxide hydrolase induce sister-chromatid exchanges in mammalian cells, but do not induce gene mutations in Salmonella typhimurium and V79 cells
    • Krämer A., Pudil J., Frank H., Setiabudi F., Oesch F., Glatt H.R. Some substrates and inhibitors of cytosolic epoxide hydrolase induce sister-chromatid exchanges in mammalian cells, but do not induce gene mutations in Salmonella typhimurium and V79 cells. Mutat. Res. 290:1993;165-174.
    • (1993) Mutat. Res. , vol.290 , pp. 165-174
    • Krämer, A.1    Pudil, J.2    Frank, H.3    Setiabudi, F.4    Oesch, F.5    Glatt, H.R.6
  • 24
    • 0010562279 scopus 로고    scopus 로고
    • Benzylic hydroxylation of 1-methylpyrene by cytochrome P450 species expressed in V79 cells
    • Engst W., Landsiedel R., Hermersdörfer H., Doehmer J., Glatt H.R. Benzylic hydroxylation of 1-methylpyrene by cytochrome P450 species expressed in V79 cells. Exp. Toxicol. Pathol. 48(Suppl. II):1996;102-108.
    • (1996) Exp. Toxicol. Pathol. , vol.48 , Issue.SUPPL. II , pp. 102-108
    • Engst, W.1    Landsiedel, R.2    Hermersdörfer, H.3    Doehmer, J.4    Glatt, H.R.5
  • 26
    • 0024518120 scopus 로고
    • Mutagenicity spectra in Salmonella typhimurium strains of glutathione, L-cysteine and active oxygen species
    • Glatt H.R. Mutagenicity spectra in Salmonella typhimurium strains of glutathione, L-cysteine and active oxygen species. Mutagenesis. 4:1989;221-227.
    • (1989) Mutagenesis , vol.4 , pp. 221-227
    • Glatt, H.R.1
  • 28
    • 0024374662 scopus 로고
    • Metabolic activation of the carcinogen 6-hydroxymethylbenzo[a]pyrene: Formation of an electrophilic sulfuric acid ester and benzylic DNA adducts in rat liver in vivo and in reactions in vitro
    • Surh Y.-J., Liem A., Miller E.C., Miller J.A. Metabolic activation of the carcinogen 6-hydroxymethylbenzo[a]pyrene: formation of an electrophilic sulfuric acid ester and benzylic DNA adducts in rat liver in vivo and in reactions in vitro. Carcinogenesis. 10:1989;1519-1528.
    • (1989) Carcinogenesis , vol.10 , pp. 1519-1528
    • Surh, Y.-J.1    Liem, A.2    Miller, E.C.3    Miller, J.A.4
  • 29
    • 0022291757 scopus 로고
    • Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver
    • E. Huberman, & S.H. Barr. New York: Raven Press
    • Miller E.C., Miller J.A., Boberg E.W., Delclos K.B., Lai C.-C., Fennell T.R., Wiseman R.W., Liem A. Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver. Huberman E., Barr S.H. Carcinogenesis. 1985;93-107 Raven Press, New York.
    • (1985) Carcinogenesis , pp. 93-107
    • Miller, E.C.1    Miller, J.A.2    Boberg, E.W.3    Delclos, K.B.4    Lai, C.-C.5    Fennell, T.R.6    Wiseman, R.W.7    Liem, A.8
  • 30
    • 0024413050 scopus 로고
    • Early years of the Salmonella mutagen tester strains: Lessons from hycanthone
    • Hartman P.E. Early years of the Salmonella mutagen tester strains: lessons from hycanthone. Environ. Mol. Mutagen. 16:1989;39-45.
    • (1989) Environ. Mol. Mutagen. , vol.16 , pp. 39-45
    • Hartman, P.E.1
  • 32
    • 0028168009 scopus 로고
    • Reduced genotoxicity of [D-5-ethyl]-tamoxifen implicates α-hydroxylation of the ethyl group as a major pathway of tamoxifen activation to a liver carcinogen
    • Phillips D.H., Potter G.A., Horton M.N., Hewer A., Croftonsleigh C., Jarman M., Venitt S. Reduced genotoxicity of [D-5-ethyl]-tamoxifen implicates α-hydroxylation of the ethyl group as a major pathway of tamoxifen activation to a liver carcinogen. Carcinogenesis. 15:1994;1487-1492.
    • (1994) Carcinogenesis , vol.15 , pp. 1487-1492
    • Phillips, D.H.1    Potter, G.A.2    Horton, M.N.3    Hewer, A.4    Croftonsleigh, C.5    Jarman, M.6    Venitt, S.7
  • 33
    • 0028172454 scopus 로고
    • 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite
    • 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite. Carcinogenesis. 15:1994;2087-2094.
    • (1994) Carcinogenesis , vol.15 , pp. 2087-2094
    • Randerath, K.1    Moorthy, B.2    Mabon, N.3    Sriram, P.4
  • 34
    • 0023933978 scopus 로고
    • Bioalkylation and bio-oxidation of anthracene, in vitro and in vivo
    • Myers S.R., Blake J.W., Flesher J.M. Bioalkylation and bio-oxidation of anthracene, in vitro and in vivo. Biochem. Biophys. Res. Commun. 151:1988;1441-1445.
    • (1988) Biochem. Biophys. Res. Commun. , vol.151 , pp. 1441-1445
    • Myers, S.R.1    Blake, J.W.2    Flesher, J.M.3
  • 35
    • 0029920334 scopus 로고    scopus 로고
    • Oxidation of 9-alkylanthracenes by cytochrome P450 2B1, horseradish peroxidase and iron tetraphenylporphine iodosylbenzene systems: Anaerobic and aerobic mechanisms
    • Anzenbacher P., Niwa T., Tolbert L.M., Sirimanne S.R., Guengerich F.P. Oxidation of 9-alkylanthracenes by cytochrome P450 2B1, horseradish peroxidase and iron tetraphenylporphine iodosylbenzene systems: anaerobic and aerobic mechanisms. Biochemistry. 35:1996;2512-2520.
    • (1996) Biochemistry , vol.35 , pp. 2512-2520
    • Anzenbacher, P.1    Niwa, T.2    Tolbert, L.M.3    Sirimanne, S.R.4    Guengerich, F.P.5
  • 36
    • 0025284601 scopus 로고
    • 1-Hydroxy- and 2-hydroxy-3-methylcholanthrene: Regioselective and stereoselective formations in the metabolism of 3-methylcholanthrene and enantioselective disposition in rat liver microsomes
    • Shou M., Yang S.K. 1-Hydroxy- and 2-hydroxy-3-methylcholanthrene: regioselective and stereoselective formations in the metabolism of 3-methylcholanthrene and enantioselective disposition in rat liver microsomes. Carcinogenesis. 11:1990;933-940.
    • (1990) Carcinogenesis , vol.11 , pp. 933-940
    • Shou, M.1    Yang, S.K.2
  • 37
    • 0029550674 scopus 로고
    • Intrinsic mutagenicity and electrophilicity of 1-sulfooxy-3-methylcholanthrene: Implications for metabolic activation of the carcinogen 3-methylcholanthrene
    • Jeong H.K., Shlyankevich M., Surh Y.J. Intrinsic mutagenicity and electrophilicity of 1-sulfooxy-3-methylcholanthrene: implications for metabolic activation of the carcinogen 3-methylcholanthrene. Biochem. Mol. Biol. Int. 37:1995;885-893.
    • (1995) Biochem. Mol. Biol. Int. , vol.37 , pp. 885-893
    • Jeong, H.K.1    Shlyankevich, M.2    Surh, Y.J.3
  • 38
    • 0028090022 scopus 로고
    • Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases in the rat
    • Glatt H.R., Pauly K., Frank H., Seidel A., Harvey R.G., Werle-Schneider G. Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases in the rat. Carcinogenesis. 15:1994;2605-2611.
    • (1994) Carcinogenesis , vol.15 , pp. 2605-2611
    • Glatt, H.R.1    Pauly, K.2    Frank, H.3    Seidel, A.4    Harvey, R.G.5    Werle-Schneider, G.6
  • 39
    • 0027935994 scopus 로고
    • Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites
    • Heflich R.H., Neft R.E. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat. Res. 318:1994;73-174.
    • (1994) Mutat. Res. , vol.318 , pp. 73-174
    • Heflich, R.H.1    Neft, R.E.2
  • 40
  • 42
    • 0023226809 scopus 로고
    • Methylated derivatives of pyrene and fluorene: Evaluation of genotoxicity in the hepatocyte/DNA repair test and tumorigenic activity in newborn mice
    • Rice J.E., Rivenson A., Braley J., LaVoie E.J. Methylated derivatives of pyrene and fluorene: evaluation of genotoxicity in the hepatocyte/DNA repair test and tumorigenic activity in newborn mice. J. Toxicol. Environ. Health. 21:1987;525-532.
    • (1987) J. Toxicol. Environ. Health , vol.21 , pp. 525-532
    • Rice, J.E.1    Rivenson, A.2    Braley, J.3    LaVoie, E.J.4
  • 44
    • 0018166425 scopus 로고
    • Tumorigenicity studies with diol-epoxides of benzo[a]pyrene which indicate that (±)-trans-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene is an ultimate carcinogen in newborn mice
    • Kapitulnik J., Wislock P.G., Levin W., Yagi H., Jerina D.M., Conney A.H. Tumorigenicity studies with diol-epoxides of benzo[a]pyrene which indicate that (±)-trans-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene is an ultimate carcinogen in newborn mice. Cancer Res. 38:1978;354-358.
    • (1978) Cancer Res. , vol.38 , pp. 354-358
    • Kapitulnik, J.1    Wislock, P.G.2    Levin, W.3    Yagi, H.4    Jerina, D.M.5    Conney, A.H.6
  • 45
    • 0027479544 scopus 로고
    • Sulfotransferase-mediated activation of 4-hydroxy- and 3,4-dihydroxy-3,4-dihydrocyclopenta[c,d]pyrene, major metabolites of cyclopenta[c,d]pyrene
    • Surh Y.-J., Kwon H.J., Tannenbaum S.R. Sulfotransferase-mediated activation of 4-hydroxy- and 3,4-dihydroxy-3,4-dihydrocyclopenta[c,d]pyrene, major metabolites of cyclopenta[c,d]pyrene. Cancer Res. 53:1993;1017-1022.
    • (1993) Cancer Res. , vol.53 , pp. 1017-1022
    • Surh, Y.-J.1    Kwon, H.J.2    Tannenbaum, S.R.3
  • 46
    • 0019275121 scopus 로고
    • Sensitivity of the conformation of deoxyguanosine to binding at the C-8 position by N-acetylated and unacetylated 2-aminofluorene
    • Evans F.E., Miller D.W., Beland F.A. Sensitivity of the conformation of deoxyguanosine to binding at the C-8 position by N-acetylated and unacetylated 2-aminofluorene. Carcinogenesis. 1:1980;955-959.
    • (1980) Carcinogenesis , vol.1 , pp. 955-959
    • Evans, F.E.1    Miller, D.W.2    Beland, F.A.3
  • 47
    • 0027935994 scopus 로고
    • Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites
    • Heflich R.H., Neft R.E. Genetic toxicity of 2-acetylaminofluorene, 2-aminofluorene and some of their metabolites and model metabolites. Mutat. Res. 318:1994;73-174.
    • (1994) Mutat. Res. , vol.318 , pp. 73-174
    • Heflich, R.H.1    Neft, R.E.2
  • 48
    • 0017412773 scopus 로고
    • Role of sulfotransferase from rat liver in the mutagenicity of N-hydroxy-2-acetylaminofluorene in Salmonella typhimurium
    • Mulder G.J., Hinson J.A., Nelson W.L., Thorgeirsson S.N. Role of sulfotransferase from rat liver in the mutagenicity of N-hydroxy-2-acetylaminofluorene in Salmonella typhimurium. Biochem. Pharmacol. 26:1977;1356-1357.
    • (1977) Biochem. Pharmacol. , vol.26 , pp. 1356-1357
    • Mulder, G.J.1    Hinson, J.A.2    Nelson, W.L.3    Thorgeirsson, S.N.4
  • 49
    • 0019144179 scopus 로고
    • Factors responsible for the metabolic formation and inactivation of bacterial mutagens from trans-4-acetylaminostilbene
    • Glatt H.R., Oesch F., Neumann H.-G. Factors responsible for the metabolic formation and inactivation of bacterial mutagens from trans-4-acetylaminostilbene. Mutat. Res. 73:1980;237-250.
    • (1980) Mutat. Res. , vol.73 , pp. 237-250
    • Glatt, H.R.1    Oesch, F.2    Neumann, H.-G.3
  • 51
    • 0027051110 scopus 로고
    • Immunological characterization of dehydroepiandrosterone sulfotransferase from human liver and adrenal
    • Comer K.A., Falany C.N. Immunological characterization of dehydroepiandrosterone sulfotransferase from human liver and adrenal. Mol. Pharmacol. 41:1992;645-651.
    • (1992) Mol. Pharmacol. , vol.41 , pp. 645-651
    • Comer, K.A.1    Falany, C.N.2
  • 52
    • 0028078591 scopus 로고
    • Dehydroepiandrosterone sulfotransferase in the developing human fetus: Quantitative biochemical and immunological characterization of the hepatic, renal and adrenal enzymes
    • Barker E.V., Hume R., Hallas A., Coughtrie M.W.H. Dehydroepiandrosterone sulfotransferase in the developing human fetus: quantitative biochemical and immunological characterization of the hepatic, renal and adrenal enzymes. Endocrinology. 134:1994;982-989.
    • (1994) Endocrinology , vol.134 , pp. 982-989
    • Barker, E.V.1    Hume, R.2    Hallas, A.3    Coughtrie, M.W.H.4
  • 53
    • 0024309210 scopus 로고
    • Human intestinal phenol sulfotransferase: Assay conditions, activity levels and partial purification of the thermolabile form
    • Sundaram R.S., Szumlanski C., Otterness D., Van Loon J.A., Weinshilboum R.D. Human intestinal phenol sulfotransferase: assay conditions, activity levels and partial purification of the thermolabile form. Drug Metab. Dispos. 17:1989;255-264.
    • (1989) Drug Metab. Dispos. , vol.17 , pp. 255-264
    • Sundaram, R.S.1    Szumlanski, C.2    Otterness, D.3    Van Loon, J.A.4    Weinshilboum, R.D.5
  • 54
    • 0026556556 scopus 로고
    • Interindividual variability in the N-sulphation of desipramine in human liver and platelets
    • Romiti P., Giuliani L., Pacifici G.M. Interindividual variability in the N-sulphation of desipramine in human liver and platelets. Br. J. Clin. Pharmacol. 33:1992;17-23.
    • (1992) Br. J. Clin. Pharmacol. , vol.33 , pp. 17-23
    • Romiti, P.1    Giuliani, L.2    Pacifici, G.M.3
  • 55
    • 0027501606 scopus 로고
    • (+) and (-) terbutaline are sulphated at a higher rate in human intestine than in liver
    • Pacifici G.M., Eligi M., Giuliani L. (+) and (-) terbutaline are sulphated at a higher rate in human intestine than in liver. Eur. J. Clin. Pharmacol. 45:1993;483-487.
    • (1993) Eur. J. Clin. Pharmacol. , vol.45 , pp. 483-487
    • Pacifici, G.M.1    Eligi, M.2    Giuliani, L.3
  • 56
    • 0028881687 scopus 로고
    • Molecular cloning of an isoform of phenol sulfotransferase from human brain hippocampus
    • Hwang S.R., Kohn A.B., Hook V.Y.H. Molecular cloning of an isoform of phenol sulfotransferase from human brain hippocampus. Biochem. Biophys. Res. Commun. 207:1995;701-707.
    • (1995) Biochem. Biophys. Res. Commun. , vol.207 , pp. 701-707
    • Hwang, S.R.1    Kohn, A.B.2    Hook, V.Y.H.3
  • 57
    • 0030934879 scopus 로고    scopus 로고
    • Bioactivation of mutagens via sulfation
    • Glatt H.R. Bioactivation of mutagens via sulfation. FASEB J. 11:1997;314-321.
    • (1997) FASEB J. , vol.11 , pp. 314-321
    • Glatt, H.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.