Cell density and contraction regulate p38 MAP kinase-dependent responses in neonatal rat cardiac myocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 277, Issue 1 46-1, 1999, Pages

  Hines, Wirt A ^a   Thorburn, Jacqueline ^b   Thorburn, Andrew ^a,b  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

Atrial natriuretic factor; Hypertrophy; Myofibril

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ATRIAL NATRIURETIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL DENSITY; CELL SIZE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; HEART MUSCLE CELL; HYPERTROPHY; MUSCLE FIBER CONTRACTION; MUSCLE FIBER CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SARCOMERE;

EID: 0032817014     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.1.h331     Document Type: Article

References (38)

1. Abdellatif, M., S. E. Packer, L. H. Michael, D. Zhang, M. J. Charng, and M. D. Schneider. A Ras-dependent pathway regulates RNA polymerase II phosphorylation in cardiac myocytes: implications for cardiac hypertrophy. Mol. Cell. Biol. 18: 6729-6736, 1998.
2. Bogoyevitch, M. A., J. Gillespie-Brown, A. J. Ketterman, S. J. Fuller, R. Ben-Levy, A. Ashworth, C. J. Marshall, and P. H. Sugden. Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. Circ. Res. 79: 162-173, 1996.
3. Bogoyevitch, M. A., P. E. Glennon, M. B. Andersson, A. Clerk, A. Lazou, C. J. Marshall, P. J. Parker, and P. H. Sugden. Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. J. Biol. Chem. 269: 1110-1119, 1994.
4. Bogoyevitch, M. A., P. E. Glennon, and P. H. Sugden. Endothelin-1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytes. FEBS Lett. 317: 271-275, 1993.
5. Bogoyevitch, M. A., C. Marshall, and P. H. Sugden. Hypertrophic agonists stimulate the activities of the protein kinases c-Raf and A-Raf in cultured ventricular myocytes. J. Biol. Chem. 270: 26303-26310, 1995.
6. Clerk, A., S. J. Fuller, A. Michael, and P. H. Sugden. Stimulation of "stress-regulated" mitogen-activated protein kinases (Stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses. J. Biol. Chem. 273: 7228-7234, 1998.
7. Clerk, A., A. Michael, and P. H. Sugden. Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy? J. Cell Biol. 142: 523-535, 1998.
8. Eble, D. M., B. M. Cadre, M. Qi, D. M. Bers, and A. M. Samarel. Contractile activity modulates atrial natriuretic factor gene expression in neonatal rat ventricular myocytes. J. Mol. Cell. Cardiol. 30: 55-60, 1998.
9. Eble, D. M., M. Qi, S. Waldschmidt, P. A. Lucchesi, K. L. Byron, and A. M. Samarel. Contractile activity is required for sarcomeric assembly in phenylephrine-induced cardiac myocyte hypertrophy. Am. J. Physiol. 274 (Cell Physiol. 43): C1226-C1237, 1998.
10. Groom, L. A., A. A. Sneddon, D. R. Alessi, S. Dowd, and S. M. Keyse. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J. 15: 3621-3632, 1996.
11. Han, J., Y. Jiang, Z. Li, V. V. Kravchenko, and R. J. Ulevitch. Activation of the transcription factor MEF2C by the MAP kinase p38 in inflammation. Nature 386: 296-299, 1997.
12. q-induced hypertrophie gene expression in neonatal rat cardiac myocytes. J. Mol. Cell. Cardiol. 30: 485-494, 1998.
13. Hines, W. A., J. Thorburn, and A. Thorburn. A low-affinity serum response element allows other transcription factors to activate inducible gene expression. Mol. Cell. Biol. 19: 1841-1852, 1999.
14. Ito, H., Y. Hirata, M. Hiroe, M. Tsujino, S. Adachi, T. Takamoto, M. Nitta, K. Taniguchi, and F. Marumo. Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes. Circ. Res. 69: 209-215, 1991.
15. Knowlton, K. U., E. Barrachini, R. S. Ross, A. N. Harris, S. Henderson, S. M. Evans, C. C. Glembotski, and K. R. Chien. Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during α-adrenergic stimulation of neonatal rat ventricular cells. J. Biol. Chem. 266: 7759-7768, 1991.
16. 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy. J. Biol. Chem. 268: 15374-15380, 1993.
17. Makhlouf, A.A., and P. J. McDermott. Increased expression of eukaryotic initiation factor 4E during growth of neonatal rat cardiocytes in vitro. Am. J. Physiol. 274 (Heart Circ. Physiol. 43): H2133-H2142, 1998.
18. McDonough, P. M., and C. C. Glembotski. Induction of atrial natriuretic factor and myosin light chain-2 gene expression in cultured ventricular myocytes by electrical stimulation of contraction. J. Biol. Chem. 267: 11665-11668, 1992.
19. McDonough, P. M., D. S. Hanford, A. B. Sprenkle, N. R. Mellon, and C. C. Glembotski. Collaborative roles for c-Jun N-terminal kinase, c-Jun, serum response factor, and Sp1 in calcium-regulated myocardial gene expression. J. Biol. Chem. 272: 24046-24053, 1997.
20. Molkentin, J. D., J.-R. Lu, C. L. Antos, B. Markham, J. Richardson, J. Robbins, S. R. Grant, and E. N. Olson. A calcineurin-dependent transcription pathway for cardiac hypertrophy. Cell 93: 215-228, 1998.
21. Nemoto, S., Z. Sheng, and A. Lin. Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy. Mol. Cell. Biol. 18: 3518-3526, 1998.
22. Ramirez, M. T., V. P. Sah, X.-L. Zhao, J. J. Hunter, K. R. Chien, and J. H. Brown. The MEKK-JNK pathway is stimulated by a-adrenergic receptor and Ras activation and is associated with in vitro and in vivo cardiac hypertrophy. J. Biol. Chem. 272: 14057-14061, 1997.
23. Sadoshima, J., and S. Izumo. Mechanical stretch rapidly activates multiple signal transduction pathways in cardiac myocytes: potential involvement of an autocrine/paracrine mechanism. EMBO J. 12: 1681-1692, 1993.
24. Sadoshima, J., and S. Izumo. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Circ. Res. 73: 413-423, 1993.
25. ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J. 15: 775-787, 1996.
26. Sadoshima, J., Y. Xu, H. S. Slater, and S. Izumo. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 75: 977-984, 1993.
27. Sei, C. A., C. E. Irons, A. B. Sprenkle, P. M. McDonough, J. H. Brown, and C. C. Glembotski. The α-adrenergic stimulation of atrial natriuretic factor expression in cardiac myocytes requires calcium influx, protein kinase C, and calmodulin-regulated pathways. J. Biol. Chem. 266: 15910-15916, 1991.
28. Sheng, Z., K. Knowlton, J. Chen, M. Hoshijima, J. H. Brown, and K. R. Chien. Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. J. Biol. Chem. 272: 5783-5791, 1997.
29. Shubeita, H. E., P. M. McDonough, A. Harris, K. U. Knowlton, C. Glembotski, J. H. Brown, and K. R. Chien. Endothelin induction of sarcomere assembly and cardiac gene expression in ventricular myocytes: a paracrine mechanism for myocardial cell hypertrophy. J. Biol. Chem. 265: 20555-20562, 1990.
30. Simpson, P. Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an α-adrenergic response. J. Clin. Invest. 72: 732-738, 1983.
31. Thorburn, A. Ras activity is required for phenylephrine-induced activation of mitogen-activated protein kinase in cardiac muscle cells. Biochem. Biophys. Res. Commun. 205: 1417-1422, 1994.
32. Thorburn, J., M. Carlson, S. J. Mansour, K. R. Chien, N. G. Ahn, and A. Thorburn. Inhibition of a signaling pathway in cardiac muscle cells by active mitogen-activated protein kinase kinase. Mol. Biol. Cell 6: 1479-1490, 1995.
33. Thorburn, J., S. Xu, and A. Thorburn. MAP kinase- and Rho-dependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells. EMBO J. 16: 1888-1900, 1997.
34. Thorburn, J. S., J. A. Frost, and A. M. Thorburn. Mitogen activated protein kinases mediate changes in gene expression, but not cytoskeletal organization associated with cardiac muscle cell hypertrophy. J. Cell Biol. 126: 1565-1572, 1994.
35. Thuerauf, D. J., N. D. Arnold, D. Zechner, D. S. Hanford, K. M. DeMartin, P. M. McDonough, R. Prywes, and C. C. Glembotski. p38 mitogen-activated protein kinase mediates the transcriptional induction of the atrial natriuretic factor gene through a serum response element. A potential role for the transcription factor atf6. J. Biol. Chem. 273: 20636-20643, 1998.
36. Wang, Y., S. Huang, V. P. Sah, J. Ross, J. H. Brown, J. Han, and K. Chien. Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family. J. Biol. Chem. 273: 2161-2168, 1998.
37. Zechner, D., R. Craig, D. S. Hanford, P. M. McDonough, R. A. Sabbadini, and C. C. Glembotski. MKK6 activates myocardial cell NF-κB and inhibits apoptosis in a p38 mitogen-activated protein kinase-dependent manner. J. Biol. Chem. 273: 8232-8239, 1998.
38. Zechner, D., D. J. Thuerauf, D. S. Hanford, P. M. McDon-ough, and C. C. Glembotski. A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization and cardiac-specific gene expression. J. Cell Biol. 139: 115-127, 1997.