Spur cell anaemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation

Gut

Volumn 45, Issue 2, 1999, Pages 301-305

  Pascoe, A ^a   Kerlin, P ^a   Steadman, C ^a   Clouston, A ^a   Jones, D ^a   Powell, L ^b   Jazwinska, E ^b   Lynch, S ^a   Strong, R ^a  

^a PRINCESS ALEXANDRA HOSPITAL   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Alcoholic liver disease; Haemochromatosis; Hepatic iron index; Orthotopic liver transplantation

Indexed keywords

ALCOHOL; FERRITIN; HEMOGLOBIN; IRON; TRANSFERRIN;

ACANTHOCYTOSIS; ADULT; AGED; ALCOHOL LIVER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROCYTE STRUCTURE; EXPLANT; FEMALE; GENE MUTATION; HEMOCHROMATOSIS; HEMOLYTIC ANEMIA; HUMAN; HUMAN CELL; HUMAN TISSUE; IRON OVERLOAD; IRON STORAGE; LIVER CELL; LIVER TRANSPLANTATION; MALE; PRIORITY JOURNAL; SIDEROSIS;

EID: 0032816831     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.45.2.301     Document Type: Article

References (29)

1. Simon M, Bourel M, Genetet B, et al. Idiopathic haemochromatosis: demonstration of recessive transmission and early detection by family HLA typing. N Engl J Med 1977;297:1017-21.
2. Cartwright GE, Edwards CQ, Kraritz K, et al. Hereditary haemochromatosis: phenotypic expression of the disease. N Engl J Med 1979;301:175-9.
3. Bassett ML, Halliday JW, Powell LW. Value of hepatic iron measurements in early haemochromatosis and determination of the critical iron level associated with fibrosis. Hepatology 1986;6:24-9.
4. Summers KM, Halliday JW, Powell LW. Identification of homozygous haemochromatosis subjects by measurement of hepatic iron index. Hepatology 1990;13:20-5.
5. Powell LW, Fletcher LM, Halliday JW. Distinction between haemochromatosis and alcoholic siderosis. In: Hall P, ed. Alcholic liver disease, pathology and pathogenesis. London: Edward Arnold, 1995:199-216.
6. Villeneuvre J-P, Bilodeau M, LePage R, et al. Variability in hepatic iron concentration measurement from needle biopsy specimen. J Hepatol 1996;25:172-7.
7. Ambu R, Crisponi G, Sciot R, et al. Uneven hepatic iron and phosphorous distribution in beta-thalassemia. J Hepatol 1995;23:544-9.
8. Ludwig J, Hashimoto E, Porayko M, et al. Haemosiderosis in cirrhosis: a study of 447 native livers. Gastroenterology 1997;112:882-8.
9. Bonkovsky HL, Slaker D, Bills E, et al. Usefulness and limitations of laboratory and hepatic imaging studies in iron-storage disease. Gastroenterology 1990;99:1080-91.
10. Chapman RW, Morgan MY, Laulicht M, et al. Hepatic iron stores and markers of iron overload in alcoholics and patients with idiopathic haemochromatosis. Dig Dis Sci 1982;27:909-16.
11. Smith JA, Lonergan ET, Sterling K. Hemolytic anaemia with red cells resembling acanthocytes in alcoholic cirrhosis. N Engl J Med 1964;271:396.
12. Feder JN, Gnirke A, Thomas W, et al. A novel MHC class 1-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996;13:399-408.
13. Jazwinska EC, Cullen EM, Busfield F, et al. Haemochromatosis and HLA-H. Nat Genet 1996;14:249-51.
14. Jouanolle AM, Gandon G, Jezequel P, et al. Haemochromatosis and HLA-H. Nat Genet 1996;14:251-2.
15. Feder JN, Penny D, Irrinki A, et al. The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. Proc Natl Acad Sci USA 1998;95:1472-7.
16. Niederau C, Fischer R, Sonnenberg A, et al. Survival and causes of death in cirrhotic and non-cirrhotic patients with primary haemochromatosis. N Engl J Med 1985;313:1256-62.
17. Kilpe VE, Krakauer H, Wren RE. An analysis of liver transplant experience from 37 transplant centres as reported to medicare. Transplantation 1993;56:554-61.
18. Farrell FJ, Nguyen M, Woodley S, et al. Outcome of liver transplantation in patients with haemochromatosis. Hepatology 1994;20:404-40.
19. Poulus JE, Bacon BR. Liver transplantation for hereditary haemochromatosis. Dig Dis Sci 1996;14:316-22.
20. Searle J, Kerr JFR, Halliday JW, et al. Iron storage disease. In: MacSween RNM, Anthony PP, Scheuer PJ, et al, eds. Pathology of the liver. 3rd edn. Churchill Livingstone, 1994:219-41.
21. Barry M, Sherlock S. Measurement of liver-iron concentration in needle-biopsy specimens. Lancet 1971;i:100-3.
22. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
23. Cullen LM, Gao X, Easteal S, et al. The hemochromatosis 845 G-A and 187 C-G mutations: prevalence in non-Caucasian populations. Am J Hum Genet 1998;62:1403-7.
24. Adams PC, Bradley C, Henderson AR. Evaluation of the hepatic iron index as a diagnostic criterion for genetic haemochromatosis. J Lab Clin Med 1997;130:509-14.
25. Deugnier Y, Turlin B, le Quilleuc D, et al. A reappraisal of hepatic siderosis in patients with end-stage cirrhosis: practical implications for the diagnosis of hemochromatosis. Am J Surg Pathol 1977;21:669-75.
26. Cooper RA, Diloy-Puray M, Lando P, et al. An analysis of lipoproteins, bile acids, and red cell membranes associated with target cells and spur cells in patients with liver disease. J Clin Invest 1972;51:3182-92.
27. Cooper RA, Kimball DB, Durocher JR. Role of the spleen in membrane conditioning and hemolysis of spur cells in liver disease. N Engl J Med 1974;290:1279-84.
28. Silber R, Amorsi E, Lhowe J, et al. Spur-shaped erythrocytes in Laennec's cirrhosis. N Engl J Med 1966;275:639-43.
29. Powell LW, Jazwinska E, Halliday JW. Primary iron overload. In: Brock JH, Halliday JW, Pippard MJ, Powell LW, eds. Iron metabolism in health and disease. London: WB Saunders, 1994;227-70.