Unique properties of the large antigen of hepatitis delta virus

Journal of Virology

Volumn 73, Issue 9, 1999, Pages 7147-7152

  Moraleda, Gloria ^a   Seeholzer, Steven ^a   Bichko, Vadim ^a   Dunbrack, Roland ^a   Otto, James ^b   Taylor, John ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS ANTIGEN;

ANIMAL CELL; ARTICLE; DIMERIZATION; HEPATITIS DELTA VIRUS; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; RETICULOCYTE; VIRUS ASSEMBLY;

EID: 0032816401     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.9.7147-7152.1999     Document Type: Article

References (50)

1. Asselbergs, F. A. M., and P. Grand. 1993. A two-plasmid system for transient expression of cDNAs in primate cells. Anal. Biochem. 209:327-331.
2. Bernard, E. J., G. Kao, A. D. Cox, S. M. Sebti, A. D. Hamilton, and R. J. Muschel. 1996. The farnesyltransferase inhibitor FTI-277 radiosensitizes H-ras-transformed rat embryo fibroblasts. Cancer Res. 56:1727-1730.
3. Bichko, V., S. Barik, and J. Taylor. 1997. Phosphorylation of the hepatitis delta virus antigens. J. Virol. 71:512-518.
4. Biou, V., J. F. Gibrat, J. M. Levin, J. Robson, and J. Garnier. 1988. Secondary structure prediction: combination of three different methods. Protein Eng. 2:185-191.
5. Bordier, C. 1981. Phase separation of integral membrane proteins in Triton X-114 solution. J. Biol. Chem. 256:1604-1607.
6. Casey, P. J., and M. C. Seabra. 1996. Protein prenyltransferases. J. Biol. Chem. 271:5289-5292.
7. Chang, F. L., P. J. Chen, S. J. Tu, M. N. Chiu, C. J. Wang, and D. S. Chen. 1991. The large form of hepatitis 8 antigen is crucial for the assembly of hepatitis δ virus. Proc. Natl. Acad. Sci. USA 88:8490-8494.
8. Chao, M., S.-Y. Hsieh, and J. Taylor. 1990. Role of two forms of the hepatitis delta virus antigen: evidence for a mechanism of self-limiting genome replication. J. Virol. 64:5066-5069.
9. Dingle, K., V. Bichko, H. Zuccola, J. Hogle, and J. Taylor. 1998. Initiation of hepatitis delta virus genome replication. J. Virol. 72:4783-4788.
10. Endo, A. 1992. The discovery and development of HMG-CoA reductase inhibitors. J. Lipid Res. 33:1569-1582.
11. Farh, L., D. A. Mitchell, and R. J. Deschenes. 1995. Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway. Arch. Biochem. Biophys. 318:113-121.
12. Frishman, D., and P. Argos. 1997. Seventy-five percent accuracy in protein secondary structure prediction. Proteins 27:329-335.
13. Ganem, D. 1991. Assembly of hepadnaviral virions and subviral particles. Curr. Top. Microbiol. Immunol. 168:61-83.
14. Garoff, H., R. Hewson, and D.-J. E. Opstelten. 1998. Virus maturation by budding. Microbiol. Mol. Biol. Rev. 62:1171-1190.
15. Ghomashchi, F., X. Zhang, L. Liu, and M. H. Gelb. 1995. Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange. Biochemistry 34:11910-11918.
16. Glenn, J. S. 1995. Prenylation and virion morphogenesis, p. 83-94. In G. Dinter-Gottlieb (ed.), The unique hepatitis delta virus. R. G. Landes, Co., Austin, Tex.
17. Glenn, J. S. 1999. Shutting the door on hepatitis delta virus (HDV): sensitivity to prenylation inhibition prompts new therapeutic strategy. Viral Hepat. Rev. 5:13-26.
18. Glenn, J. S., J. C. Marsters, Jr., and H. B. Greenberg. 1998. Use of a prenylation inhibitor as a novel antiviral agent. J. Virol. 72:9303-9306.
19. Glenn, J. S., J. A. Watson, C. M. Havel, and J. O. White. 1992. Identification of a prenylation site in the delta virus large antigen. Science 256:1331-1333.
20. Glenn, J. S., and J. M. White. 1991. trans-dominant inhibition of human hepatitis delta virus genome replication. J. Virol. 65:2357-2361.
21. Gutierrez, L., A. I. Magee, C. J. Marshall, and J. F. Hancock. 1989. Posttranslational processing of p21ras is two-step and involves carboxymethylation and carboxy-terminal proteolysis. EMBO J. 8:1093-1099.
22. Hallick, R. B., B. K. Chelm, P. W. Gray, and E. M. Orozco. 1977. Use of aurintricarboxylic acid as an inhibitor of nucleases during nucleic acid isolation. Nucleic Acids Res. 4:3055-3063.
23. Hancock, J. F., H. Paterson, and C. J. Marshall. 1990. A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 63:133-139.
24. Hruby, D. E., and C. A. Franke. 1993. Viral acy proteins: greasing the wheels of assembly. Trends Microbiol. 1:20-25.
25. Hwang, S. B., and M. M. C. Lai. 1994. Isoprenylation masks a conformational epitope and enhances trans-dominant inhibitory function of the large hepatitis delta antigen. J. Virol. 68:2958-2964.
26. Hwang, S. B., and M. M. C. Lai. 1993. Isoprenylation mediates direct protein-protein interactions between hepatitis large delta antigen and hepatitis B virus surface antigen. J. Virol. 67:7659-7662.
27. Hwang, S. B., C.-Z. Lee, and M. M. C. Lai. 1992. Hepatitis delta antigen expressed by recombinant baculoviruses: comparison of biochemical properties and post-translational modifications between the large and small forms. Virology 190:413-422.
28. Jenna, S., and C. Sureau. 1998. Effect of mutations in the small envelope protein of hepatitis B virus on assembly and secretion of hepatitis delta virus. Virology 251:176-186.
29. Kim, C. M., J. L. Goldstein, and M. S. Brown. 1992. cDNA cloning of MEV, a mutant protein that facilitates cellular uptake of mevalonate, and identification of the point mutation responsible for its gain of function. J. Biol. Chem. 267:23113-23121.
30. Kinh, R. D., M. Saqi, R. Sayle, and M. J. Sternberg. 1997. DSC: public domain protein secondary structure prediction. Comput. Appl. Biosci. 13: 473-474.
31. Kneller, D. G., F. E. Cohen, and R. Langridge. 1990. Improvements in secondary structure prediction by an enhanced neural network. J. Mol. Biol. 214:171-182.
32. Kuo, M. Y.-P., M. Chao, and J. Taylor. 1989. Initiation of replication of the human hepatitis delta virus genome from cloned DNA: role of delta antigen. J. Virol. 63:1945-1950.
33. Kuo, M. Y.-P., J. Goldberg, L. Coates, W. Mason, J. Gerin, and J. Taylor. 1988. Molecular cloning of hepatitis delta virus RNA from an infected woodchuck liver: sequence, structure, and applications. J. Virol. 62:1855-1861.
34. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
35. Lazinski, D. W., and J. M. Taylor. 1993. Relating structure to function in the hepatitis delta virus antigen. J. Virol. 67:2672-2680.
36. Lee, C.-Z., P.-J. Chen, M. Lai, and D.-S. Chen. 1994. Isoprenylation of large hepatitis delta antigen is necessary but not sufficient for hepatitis delta virus assembly. Virology 199:169-175.
37. Lin, H.-p., S.-C. Hsu, J.-C. Wu, I.-J. Sheen, B.-S. Yan, and W.-J. Syu. 1999. Localization of isoprenylated antigen of hepatitis delta virus by anti-farnesyl antibodies. J. Gen. Virol. 80:91-96.
38. Luo, G., M. Chao, S.-Y. Hsieb, C. Sureau, K. Nishikura, and J. Taylor. 1990. A specific base transition occurs on replicating hepatitis delta virus RNA. J. Virol. 64:1021-1027.
39. Lupas, L., M. Van Dyke, and J. Stock. 1991. Predicting coiled coils from protein sequences. Science 252:1162-1164.
40. Marshall, C. J. 1993. Protein prenylation: a mediator of protein-protein interactions. Science 259:1865-1866.
41. Nakabayashi, H., K. Taketa, K. Miyano, T. Yamane, and J. Sato. 1982. Growth of human hepatoma cell lines with differentiated functions in chemically defined medium. Cancer Res. 42:3858-3863.
42. Otto, J. C., and P. J. Casey. 1996. The hepatitis delta virus large antigen is farnesylated both in vitro and in animal cells. J. Biol. Chem. 271:4569-4572.
43. Ponzetto, A., P. J. Cote, H. Popper, B. H. Hoyer, W. T. London, E. C. Ford, F. Bonino, R. H. Purcell, and J. L. Gerin. 1984 Transmission of the hepatitis B virus-associated δ agent to the eastern woodchuck. Proc. Natl. Acad. Sci. USA 81:2208-2212.
44. Pryde, J. G. 1986. Triton X-114: a detergent that has come in from the cold. Trends Biochem. Sci. 11:160-163.
45. Rost, B. 1996. PHD: predicting one-dimensional protein structure by profile based neural networks. Methods Enzymol. 266:525-539.
46. Ryu, W.-S., M. Bayer, and J. Taylor. 1992. Assembly of hepatitis delta virus particles. J. Virol. 66:2310-2315.
47. Sasseville, A. M.-J., and Y. Raymond. 1995. Lamin A precursor is localized to intranuclear foci. J. Cell Sci. 108:273-285.
48. Wu, H.-L., P.-J. Chen, J.-J. Mu, W.-K. Chi, T.-L. Kao, L.-H. Hwang, and D.-S. Chen. 1997. Assembly of hepatitis delta virus-like empty particles in yeast. Virology 236:374-381.
49. Xia, Y.-P., and M. M. C. Lai. 1992. Oligomerization of hepatitis delta antigen is required for both the trans-activating and trans-dominant inhibitory activities of the delta antigen. J. Virol. 66:6641-6648.
50. Zuccola, H. J., J. E. Rozzelle, S. M. Lemon, B. W. Erickson, and J. M. Hogle. 1998. Structural basis of the oligomerization of hepatitis delta antigen. Structure 6:821-830.