Common conformational effects in the P53 protein of vinyl chloride- induced mutations

Journal of Protein Chemistry

Volumn 18, Issue 4, 1999, Pages 467-472

  Chen, James M ^a   Smith, Steven J ^b   Marion, Marie Jeanne ^c   Pincus, Matthew R ^d,e   Brandt Rauf, Paul W ^b  

^a PFIZER INC   (United States)

^b Columbia Univ Sch of Public Health ^*  (United States)

^c INSERM   (France)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Immunohistochemistry; Molecular dynamics; Mutation; p53; Vinyl chloride

Indexed keywords

PROTEIN P53; VINYL CHLORIDE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; HUMAN; IMMUNOHISTOCHEMISTRY; MOLECULAR DYNAMICS; NUCLEIC ACID BASE SUBSTITUTION; PROTEIN CONFORMATION; PROTEIN DNA BINDING; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOGENS; CRYSTALLOGRAPHY, X-RAY; GENES, P53; HEMANGIOSARCOMA; HUMANS; IMMUNOENZYME TECHNIQUES; LEUCINE; LIVER NEOPLASMS; MICE; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN CONFORMATION; TUMOR SUPPRESSOR PROTEIN P53; VINYL CHLORIDE;

EID: 0032815632     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020644826867     Document Type: Article

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