The lawc gene is a new member of the trithorax-group that affects the function of the gypsy insulator of Drosophila

Genetics

Volumn 152, Issue 3, 1999, Pages 1045-1055

  Zorin, Izanne D ^a   Gerasimova, Tatiana I ^a   Corces, Victor G ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN LAWC; PROTEIN TRITHORAX; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CHROMATIN; DNA SEQUENCE; DROSOPHILA; GENE MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN LOCALIZATION; RETROPOSON;

ANIMALS; CELL NUCLEUS; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; MALE; MULTIGENE FAMILY; MUTAGENESIS; PHENOTYPE; PIGMENTATION; RECOMBINANT PROTEINS; TRANSCRIPTION FACTORS;

HEXAPODA; INVERTEBRATA;

EID: 0032812492     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. ADAMSON, A. L., and A. SHEARN, 1996 Molecular genetic analysis of Drosophila ash-2, a member of the trithorax Group required for imaginal disc formation. Genetics 144: 621-633.
2. BREEN, T. R., and P. J. HARTE, 1993 trithorax regulates multiple homeotic genes in the bithorax and Antennapedia complexes and exerts different tissue-specific, parasegment-specific and promoter-specific effects on each. Development 117: 119-134.
3. CAPDEVILA, M. P., and A. GARCIA-BELLIDO, 1981 Genes involved in the activation of the bithorax complex of Drosophila. Wilhelm Roux's Arch. 190: 339-350.
4. CAPDEVILA, M. P., J. BOTAS and A. GARCIA-BELLIDO, 1986 Genetic interactions between the Polycomb locus and the Antennapedia and bithorax complexes of Drosophila. Roux's Arch. Dev. Biol. 195: 417-432.
5. CASPERSON, T., and J. SCHULTZ, 1938 Nucleic acid metabolism of the chromosomes in relation to gene reproduction. Nature 142: 294-295.
6. CHUNG, J. H., A. C. BELL and G. FELSENFELD, 1997 Characterization of the chicken β-globin insulator. Proc. Natl. Acad. Sci. USA 94: 575-580.
7. DORN, R., V. KRAUSS, G. REUTER and H. SAUMWEBER, 1993 The enhancer of position-effect variegation of Drosophila E(var)3-93D codes for a chromatin protein containing a conserved domain common to several transcriptional regulators. Proc. Natl. Acad. Sci. USA 90: 11376-11380.
8. DUNCAN, I. M., 1982 Polycomblike: a gene that appears to be required for the normal expression of the bithorax and Antennapedia gene complexes of Drosophila melanogaster. Genetics 102: 49-70.
9. DURA, J. M., and H. W. BROCK, 1985 Polyhomeotic: a gene of Drosophila melanogaster required for correct expression of segmental identity. Mol. Gen. Genet. 198: 213-220.
10. EISSENBERG, J. C., T. C. JAMES, D. M. FOSTER-HARTNETT, V. NGAN and S. C. ELGIN, 1990 Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 87: 9923-9927.
11. ELFRING, L. K., C. DANIEL, O. PAPOULAS, R. DEURING, M. SARTE et al., 1998 Genetic analysis of brahma: the Drosophila homolog of the yeast chromatin remodeling factor SW12/SNF2. Genetics 148: 251-265.
12. FARKAS, G., J. GAUSZ, M. GALLONI, G. REUTER, H. GYURKOVICS et al., 1994 The Trithorax-like gene encodes the Drosophila GAGA factor. Nature 371: 806-808.
13. GDULA, D. A., T. I. GERASIMOVA and V. G. CORCES, 1996 Genetic and molecular analysis of the gypsy chromatin insulator of Drosophila. Proc. Natl. Acad. Sci. USA 93: 9378-9383.
14. GERASIMOVA, T. I., and V. G. CORCES, 1996 Boundary and insulator elements in chromosomes. Curr. Opin. Genet. Dev. 6: 185-192.
15. GERASIMOVA, T. I., and V. G. CORCES, 1998 Polycomb and trithorax group proteins mediate the function of a chromatin insulator. Cell 92: 511-521.
16. GERASIMOVA, T. I., D. A. GDULA, D. V. GERASIMOV, O.B. SIMONOVA and V. G. CORCES, 1995 A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation. Cell 82: 587-597.
17. GEYER, P. K., and V. G. CORCES, 1992 DNA position-specific repression of transcription by a Drosophila Zn finger protein. Genes Dev. 6: 1865-1873.
18. GINDHART, J. G., and T. C. KAUFMAN, 1995 Identification of Polycomb and trithorax Group responsive elements in the regulatory region of the Drosophila homeotic gene Sex combs reduced. Genetics 139: 797-814.
19. HAGSTROM, K., M. MULLER and P. SCHEDL, 1996 Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes Dev. 10: 3202-3215.
20. INGHAM, P. W., 1983 Differential expression of bithorax complex genes in the absence of the extra sex combs and trithorax genes. Nature 306: 591-593.
21. INGHAM, P. W., 1985 A clonal analysis of the requirements for the trithorax gene in the diversification of segments in Drosophila. J. Embryol. Exp. Morphol. 89: 349-365.
22. INGHAM, P. W., and A. MARTINEZ-ARIAS, 1986 The correct activation of the Antennapedia and bithorax complex genes requires the fuzhi tarazu gene. Nature 324: 592-597.
23. JACK, J., D. DORSETT, Y. DELOTTO and S. LIU, 1991 Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distal enhancer. Development 113: 735-747.
24. JAMES, T. C., and S. C. ELGIN, 1986 Identification of a nonhistone chromosomal protein associated with heterochromatin in Drosophila melanogaster and its gene. Mol. Cell. Biol. 6: 3862-3872.
25. KALOS, M., and R. E. K. FOURNIER, 1995 Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domain. Mol. Cell. Biol. 15: 198-207.
26. KAUFMAN, T. C., R. LEWIS and B. WAKIMOTO, 1980 Genetic analysis of chromosome 3 in Drosophila melanogaster: the homeotic gene complex in polytene chromosome interval 84A-B. Genetics 94: 115-133.
27. KELLUM, R., and P. SCHEDL, 1991 A position-effect assay for boundaries of higher order chromosomal domains. Cell 64: 941-950.
28. KELLUM, R., and P. SCHEDL, 1992 A group of scs elements function as domain boundaries in an enhancer-blocking assay. Mol. Cell. Biol. 12: 2424-2431.
29. KENNISON, J. A., 1995 The polycomb and trithorax group proteins of Drosophila: trans-regulators of homeotic gene function. Annu. Rev. Genet. 29: 289-303.
30. KENNISON, J. A., and J. W. TAMKUN, 1988 Dosage-dependent modifiers of Polycomb and Antennapedia mutations in Drosophila. Proc. Natl. Acad. Sci. USA 85: 8136-8140.
31. KUZIORA, M. A., and W. MCGINNIS, 1988 Different transcripts of the Drosophila AbdBgene correlate with distinct genetic sub-functions. EMBO J. 7: 3233-3244.
32. LAJEUNESSE, D., and A. SHEARN, 1995 Trans-regulation of thoracic homeotic selector genes of the Antennapedia and bithorax complexes by the trithorax group genes: absent, small and homeotic discs 1 and 2. Mech. Dev. 53: 123-139.
33. LEVEFRE, G., 1976 The Genetics and Biology of Drosophila, Vol. 1a, edited by M. ASHBURNER and E. NOVITSKI, Academic Press, New York, pp. 31-66.
34. LEWIS, E. B., 1978 A gene complex controlling segmentation in Drosophila. Nature 276: 565-570.
35. MIHALY, J., I. HOGGA, J. GAUSZ, H. GYURKOVICS and F. KARCH, 1997 In situ dissection of the Fab-7 region of the bithorax complex into a chromatin domain boundary and a Polycomb-response element. Development 124: 1809-1820.
36. ORLANDO, V., and R. PARO, 1993 Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin. Cell 75: 1187-1198.
37. PARO, R., and P. J. HARTE, 1996 The role of Polycomb group and trithorax group chromatin complexes in the maintenance of determined cell states, pp. 507-528 in Epigenetic Mechanisms of Gene Regulation, edited by V. E. A. RUSSO, R. A. MARTIENSSEN and A. D. RIGGS. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
38. ROSEMAN, R. R., V. PIRROTTA and P. K. GEYER, 1993 The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects. EMBO J. 12: 435-442.
39. SHEARN, A., 1989 The ash-1, ash-2 and trithorax genes of Drosophila melanogaster are functionally related. Genetics 121: 517-525.
40. SIMONOVA, O. B., B. A. KUZIN, P. G. GEORGIEV and T. I. GERASIMOVA, 1992 Novel regulatory mutation of Drosophila melanogaster. Genetika (Russ.) 28: 164-167.
41. STRUHL, G., 1981 A gene product required for correct initiation of segmental determination in Drosophila. Nature 293: 36-41.
42. TSAI, S. F, C. C. JANG, G. G. PRIKHOD'KO, D. A. BESSARAB, C. Y. TANG et al., 1997 Gypsy retrotransposon as a tool for the in vivo analysis of the regulatory region of the optomotor-blind gene in Drosophila. Proc. Natl. Acad. Sci. USA 94: 3837-3841.
43. TSUKIYAMA, T., P. B. BECKER and C. WU, 1994 ATP-dependent nucleosome disruption at a heat shock promoter mediated by binding of GAGA transcription factor. Nature 367: 525-532.
44. ZHOU, J., S. BAROLO, P. SZYMANSKI and M. LEVINE, 1996 The Fab-7 element of the bithorax complex attenuates enhancer-promoter interactions in the Drosophila embryo. Genes Dev. 10: 3195-3201.