Onychomycosis: A compendium of facts and a clinical experience

Journal of Foot and Ankle Surgery

Volumn 38, Issue 4, 1999, Pages 290-302

  Schlefman, Barbara S ^a  

^a NONE   (United States)

Author keywords

Fluconazole; Fungal nails; Itraconazole; Onychomycosis; Terbinafine

Indexed keywords

ASTEMIZOLE; CARBAMAZEPINE; CIMETIDINE; CISAPRIDE; CYCLOSPORIN; CYCLOSPORIN A; DIGOXIN; FLUCONAZOLE; GRISEOFULVIN; GRISFULVIN; ITRACONAZOLE; KETOCONAZOLE; MEVINOLIN; MIDAZOLAM; PHENYTOIN; SIMVASTATIN; TERBINAFINE; TERFENADINE; TRIAZOLAM; UNCLASSIFIED DRUG; WARFARIN; ZIDOVUDINE;

DIFFERENTIAL DIAGNOSIS; DISEASE PREDISPOSITION; DRUG COST; DRUG EFFICACY; DRUG INDICATION; DRUG MECHANISM; GASTROINTESTINAL DISEASE; HEADACHE; HEMATOLOGIC DISEASE; HUMAN; LABORATORY DIAGNOSIS; ONYCHOMYCOSIS; ORAL DRUG ADMINISTRATION; REVIEW;

EID: 0032811723     PISSN: 10672516     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1067-2516(99)80072-6     Document Type: Review

References (48)

1. Jones, H. E., Zaias, N. Double-blind, randomized comparison of itraconazole capsules and placebo in onychomycosis of toenail. Int. J. Dermatol. 35(8):589-90, 1996.
2. Phillips, P. New drugs for the nail fungus prevalent in elderly. JAMA 276(1):12-13, 1996.
3. Odom, R. B. New therapies for onychomycosis. J. Am. Acad. Dermatol 35(3 Pt 2):S26-30, 1996.
4. Gupta, A. K., Shear, N. H. Onychomycosis. Going for cure. Can. Fam. Physician 43:299-305, 1997.
5. Daniel, C. R. Traditional management of onychomycosis. J. Am. Acad Dermatol. 35(3 Pt 2):S21-5, 1996.
6. Brautigam, M., Nolting, S., Schopf, R. E., Weidinger, G. German randomized double-blind multicenter comparison of terbinafine and itraconazole for the treatment of toenail tinea infection. Br. J. Dermatol. 134 (suppl. 46)18-21, 38, 1996.
7. Gupta, A. K., Scher, R. K., De Doncker, P. Current management of onychomycosis. An Overview. Dermarol. Clin. 15(1):121, 35, 1997.
8. Gupta, A. K., Sauder, D. N., Shear, N. H Antifungal agents: an overview. Part II. J. Am Acad. Dermatol. 30(6):911-924, 1994.
9. Segal, R., Kritzman, A., Vicidalli, L., Samra, Z., David, M., Tiqva, P. Treatment of Candida nail infection with terbinafine. J. Am. Acad Dermatol. 35(6):958-961, 1996.
10. Elewski, B. E., Hay, R. J. Update on the management of onychomycosis: Highlights of the Third Annual International Summit on Cutaneous Antifungal Therapy. Clin. Infect. Dis. 23(2):305-313, 1996.
11. De Doncker, P. R., Scher, R. K., Baran, R. L., Decroix, J., Degreef, H. J., Roseeuw, D. I., Havu, V., Rosen, T., Gupta, A. K., Pierard, G. E. Itraconazole therapy is effective for pedal onychomycosis caused by some nondermatophyte molds and in mixed infection with dermatophytes and molds: a multicenter study with 36 patients. J. Am. Acad Dermatol. 36(2 Pt 1):173-117, 1997.
12. Zaias, N., Glick, B., Rebell, G Diagnosing and treating onychomycosis. J. Fam. Pract. 42(5):513-518, 1996.
13. Wenig, J. A. The systemic treatment of onychomycosis. Clin. Podiatr Med. Surg. 12(2):263-274, 1995.
14. Bodman, M. A., Brlan, M. R. Superficial white onychomycosis. J Am. Podiatr. Med. Assoc. 85(4):205-208, 1995.
15. Luyten, C., Andre, J., Walraevens, C., De Doncker, P. Yellow nail syndrome and onychomycosis. Dermatology 192:406-408, 1996.
16. Elewski, B., Hay, R. International summit on cutaneous antifungal therapy : Onychomycosis - the new challenge. Unpublished material, May 1996.
17. McCord, J. H. New oral treatments - a groundbreaking strategy. Podiatry Today 10(2):1-4, 1997.
18. Chiritescu, M. M., Chiritescu, M. E., Scher, R. K. Newer svstemic antifungal drugs for the treatment of onychomycosis. Clin. Podiatr. Med. Surg. 13(4):741-758, 1996.
19. Brautigam, M., Nolting, S., Schopf, R. E., Weidinger, G. Randomized double blind comparison of terbinafine and itraconazole for treatment of toenail tinea infection. Br. Med. J. 311(7010):919-922, 1995.
20. Roberts, D. T., Oral therapeutic agents in fungal nail disease. J. Am. Acad. Dermatol. 31.S78-81, 1994.
21. O'Sullivan, D. P., Needham, C. A., Bangs, A., Atkin, K., Kendall, F. D Postmarketing surveillance of oral terbinafine in the UK: Report of a large cohort study. Br J. Clin. Pharmacol. 42:559-565, 1996.
22. Nolting, S., Brautigam, M., Weidinger, G. Terbinafine in onychomycosis with involvement by non-dermatophytes fungi Br. J. Dermatol. 130 (suppl 43):16-21, 1994.
23. Jones, K. W. Drugs Ther. Perspect. 7(1):1-5, 1996.
24. Shear, N. H., Villars, V. V., Marsolais, C. Terbinafine: an oral and topical antifungal agent. Clin. Dermatol. 9:487-495, 1992.
25. Assaf RR, Elewski BE. Intermittent fluconazole dosing in patients with onychomycosis: results of a pilot study. J. Am. Acad Dermatol. 35(2 Pt 1):216-219, 1996.
26. Bonifaz, A., Carraso-Gerard, E., Saul, A. Itraconazole in onychomycosis: intermittent dose schedule. Int. J. Dermatol. 36(1):70-72, 1997.
27. De Backer, M., De Keyser, P , De Vroey, C., Lesaffre, E. A 12-week treatment for dermatophytes toe onychomycosis: terbinafine 250 mg/day vs. itraconazole 200 mg/day-a double-blind comparative trial. Br. J. Dermatol. 134 (suppl 46) 16-17, 1996.
28. De Cuyper, C. Long-term evaluation of terbinafine 250 and 500 mg daily in a 16-week oral treatment for toenail onychomycosis [letter]. Br. J. Dermatol. 135(1):156-157, 1996.
29. De Doncker, P., Decroix, J., Pierard, G. E., Roelant, D., Woestenborghs, R., Jacqmin, P., Odds, F., Heremans, A., Dockx, P., Doseeuw, D. Antifungal pulse therapy for onychomycosis. A pharmacokinetic and pharmacodynamic investigation of monthly cycles of 1-week pulse therapy with itraconazole. Arch. Dermatol. 132(1).34-41, 1996.
30. De Doncker, P., Van Lint, J., Dockx, P., Roseeuw, D. Pulse therapy with one-week itraconazole monthly for three or four months in the treatment of onychomycosis. Cutis 56(3):180-183, 1995.
31. Elewski, B. E., Scher, R. K., Aly, R., Daniel, R., Jones, H. E., Odom, R. B., Zaias, N., Jacko, M. L. Double-blind, randomized comparison of itraconazole capsules vs placebo in the treatment of toenail onychomycosis. Cutis 59(4):217-220, 1997.
32. Faergemann, J., Anderson, C., Hersle, K., Hradil, E., Nordin, P., Kaaman, T., Molin, L., Pettersson, A. Double-blind, parallel-group comparison of terbinafine and griseofulvin in the treatment of toenail onychomycosis. J. Am. Acad. Dermatol 126 (suppl.39):33-35, 1995.
33. Farki, J., Heikkila, H., Kero, M., et al. Fluconazole in the treatment of onychomycosis: an open non-comparative multi-center study with oral 150-mg fluconazole once weekly. Future trends in the treatment of dermatomycoses. Dermatology 2000, Vienna, abstract book, poster, May 1993.
34. Galimberti, R , Kowalczuk, A., Flores, V., Squiquera, L. Onychomycosis treated with a short course of oral terbinafine. Int. J. Dermatol. 35(5):374-375, 1996.
35. Havu, V., Brandt, H., Heikkila, H., Hollmen, A., Oksman, R., Rantanen, T., Saari, S., Stubb, S., Turjanmaa, J , Piepponen, T. A double-blind, randomized study comparing itraconazole pulse therapy with continuous dosing for the treatment of toe-nail onychomycosis. Br. J. Dermatol. 136(2):230-234, 1997.
36. Heikkila, H., Stubb, S. Long-term results of patients with onychomycosis treated with itraconazole. Acta. Dermatol Venereol. 77(1):70-71, 1997.
37. Hofmann, H., Brautigam, M., Weidinger, G., Zaun, H. Treatment of toenail onychomycosis, a randomized, double-blind study with terbinafine and griseofulvin. Arch. Dermatol. 131:919-922, 1995.
38. Kuokkanen, K., Flava, S. Fluconazole in the treatment of onychomycosis caused by dermatophytes. J. Dermatol. Treat. 3:115-117, 1992.
39. Arenas, R., Dominguez-Cherit, J., Fernandez, L. M. Open randomized comparison of itraconazole versus terbinafine in onychomycosis. Int. J. Dermatol. 34:138-143, 1995.
40. Odom, R., Daniel, C. R., Aly, R A double-blind, randomized comparison of itraconazole capsules and placebo in the treatment of onychomycosis of the toenail. J. Am. Acad. Dermatol. 35(1):110-111, 1996.
41. Svejgaard, E. L., Brandrup, F., Kragballe, K , Larsen, P. O., Veien, N K., Holst, M., Andersen, B. L., Bro-Jorgensen, A. V., Dahl, J. C., Frentz, G., Graudal, C., Kamp, P., Korman, N., Larsen, F. S., Mikkelsen, F., Munkvad, N. J., Olafsson, J. H., Rothenborg, H , Staberg, B., Sondergaard, J., Thulin, H. Oral terbinafine in toenail dermatophytosis. A double-blind, placebo-controlled multicenter study with 12 months' follow-up. Acta. Derm. atol. Venereol. 77(1):66-69, 1997.
42. Tosti, A., Piraccini, B. M., Stinchi, C., Venturo, N., Bardazzi, F., Colombo, M. D. Treatment of dermatophytes nail infections: an open randomized study comparing intermittent terbinafine therapy with continuous terbinafine treatment and intermittent itraconazole therapy. J. Am. Acad. Dermatol. 34(4):595-600, 1996.
43. Faergemann, J., Laufen, H. Levels of fluconazole in normal and diseased nails during and after treatment of onychomycosis in toenails with fluconazole 150mg once weekly. Acta Derm Venereol 76(3):219-221, 1996.
44. De Keyser, P., De Backer, M., Massart, D. L., Westelinck, K. J. Two-week oral treatment of tinea pedis, comparing terbinafine (250 mg/day) with itraconazole (100 mg/day): a double-blind, multicenter study. Br. J. Dermatol. 130:22-25,1994.
45. Marchetti, A., Piech, C. T., McGhan, W. F., Neugut, A. I., Smith, B. T. Pharmacoeconomic analysis of oral therapies for onychomycosis: a US model. Clin. Ther. 18(4):757-777, 1996.
46. Einarson, T. R., Arikian, S. R., Shear, N. H. Cost-effectiveness analysis for onychomycosis therapy in Canada from a government perspective. Br. J. Dermatol. 130:32-24, 1994.
47. Elewski, B. E. Once weekly fluconazole in the treatment of onychomycosis: introduction J. Am. Acad. Dermatol. 38:S73-S76, 1998.
48. Scher, R. K., Breneman, D., Rich, P., et al. Once-weekly fluconazole (150, 300, or 450) in the treatment of distal d\subungal onychomycosis of the toenail, J. Am. Dermatol. 38:S77-S85, 1998.