Double-blind, randomized comparison of itraconazole capsules and placebo in onychomycosis of toenail

International Journal of Dermatology

Volumn 35, Issue 8, 1996, Pages 589-590

  Jones, Henry Earl ^b   Zaias, Nardo ^a  

^a MOUNT SINAI MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ITRACONAZOLE; PLACEBO;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; FEMALE; HEADACHE; HUMAN; MAJOR CLINICAL STUDY; MALE; ONYCHOMYCOSIS; ORAL DRUG ADMINISTRATION; RANDOMIZED CONTROLLED TRIAL; RHINITIS; SINUSITIS; TRICHOPHYTON RUBRUM;

EID: 0029747136     PISSN: 00119059     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-4362.1996.tb03667.x     Document Type: Article

References (8)

1. Ramesh V, Reddy BS, Singh R. Onychomycosis. Int J Dermatol 1983; 22:148-152.
2. Andre J, Achten G. Onychomycosis. Int J Dermatol 1987; 26:481-490.
3. Davies R, Everall J, Hamilton E. Mycological and clinical evaluation of griseofulvin for chronic onychomycosis. BMJ 1967; 3:464-468.
4. Heykants J, van Peer A, van de Velde V, et al. The clinical pharmacokinetics of itraconazole; an overview. Mycoses 1989; 32:67-87.
5. Heykants J, Michiels M, Meudermans W, et al. The pharmacokinetics of itraconazole in animals and man. In: Fromtling R, ed. Recent trends in discovery, development, and evaluation of antifungal agents. Barcelona, Spain: Prous Science Publishers, 1987:223-249.
6. Cauwenbergh G, DeGreef H, Heykants J, et al. Pharmacokinetic profile of orally administered itraconazole in human skin. J Am Acad Dermatol 1988; 18:263-269.
7. Matthieu L, DeDoncker P, Cauwenbergh G, et al. Itraconazole concentrations in the distal nail plate during the treatment of Onychomycosis. London: Clinical Dermatology of the Year 2000. 1990:137. [Abstr]
8. Willemsen R, DeDoncker P, Willens J, et al. Post-treatment itraconazole levels in the nail: new implications for treatment in Onychomycosis. J Am Acad Dermatol 1992; 26:731-735.