Double-blind, randomized comparison of itraconazole capsules vs. placebo in the treatment of toenail onychomycosis

Cutis

Volumn 59, Issue 4, 1997, Pages 217-220

  Elewski, Boni E ^a,b   Scher, Richard K ^a,c   Aly, Raza ^a,d   Daniel III, Ralph ^a,e   Jones, Henry Earl ^a,f   Odom, Richard B ^a,g   Zaias, Nardo ^a,h   Jacko, Mary L ^a,i  

^a University Hospitals of Cleveland ^*

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c New York Presbyterian Columbia University Medical Center   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h MOUNT SINAI MEDICAL CENTER   (United States)

ⁱ JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ITRACONAZOLE; PLACEBO; POTASSIUM HYDROXIDE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DERMATOPHYTE; DOUBLE BLIND PROCEDURE; DRUG CAPSULE; DRUG EFFICACY; HUMAN; HYPERGLYCEMIA; HYPERTENSION; LIVER TOXICITY; MAJOR CLINICAL STUDY; MALAISE; MULTICENTER STUDY; MYALGIA; ONYCHOMYCOSIS; ORAL DRUG ADMINISTRATION; ORTHOSTATIC HYPOTENSION; RANDOMIZED CONTROLLED TRIAL; RASH; STOMACH PAIN; SYMPTOMATOLOGY; TOE; TRICHOPHYTON RUBRUM; VASCULITIS;

EID: 0031425905     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Ramesh V, Reddy BSN, Singh R: Onychomycosis. Int J Dermatol 148-152, 1983.
2. Scher R, Daniel CR III: Nails: Therapy Diagnosis, Surgery. Philadelphia, WB Saunders, 1990.
3. Zaias N: Onychomycosis. Dermatol Clin 3: 445-460, 1985.
4. Holub P, Hubbard E: Ketoconazole in the treatment of onychomycosis. J Am Podiatr Med Assoc 77: 338-339, 1987.
5. Hay R, Clayton Y, Griffiths W, et al: A comparative double-blind study of ketoconazole and griseofulvin in dermatophytes. Br J Dermatol 112: 691-696, 1985.
6. Cauwenbergh G: Safety aspects of ketoconazole, the most commonly used systemic antifungal. Mycoses 32 (Suppl 2): 59-63, 1989.