MHC class I restricted T cell responses to Listeria monocytogenes, an intracellular bacterial pathogen

Immunologic Research

Volumn 19, Issue 2-3, 1999, Pages 211-223

  Finelli, Alyce ^a   Kerksiek, Kristen M ^a   Allen, S Elise ^a   Marshall, Natalia ^a   Mercado, Roberto ^a   Pilip, Ingrid ^a   Busch, Dirk H ^a   Pamer, Eric G ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Section of Infectious Diseases   (United States)

Author keywords

Antigen presentation; Antimicrobial immunity; Cytolytic T lymphocytes; Intracellular bacteria; Lysteria monocytogenes; MHC class Ib molecules; MHC tetramers

Indexed keywords

BACTERIAL PROTEIN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEASOME; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ANTIGEN PRESENTATION; CELL POPULATION; CYTOSOL; CYTOTOXIC T LYMPHOCYTE; HOST CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNITY; INFECTION RESISTANCE; LISTERIA MONOCYTOGENES; LISTERIOSIS; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 0032811574     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02786489     Document Type: Review

References (67)

1. Pamer EG: Immune response to Listeria monocytogenes. Austin, R G Landes, 1997.
2. Gellin BG: Broome CV Listeriosis. JAMA 1989;261:1313-1320.
3. Mengaud J, Ohayon H, Gounon P, Mege RM, Cossart P: E-cadherin is the receptor for internalin, a surface protein required for entry of L monocytogenes into epithelial cells. Cell 1996;84:923-932.
4. Gaillard JL, Berche P, Frehel C, Gouin E, Cossart P: Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from Gram-positive cocci. Cell 1991;65:1127-1141.
5. Bielecki J, Youngman P, Connelly P, Portnoy DA: Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells. Nature 1990;345:175,176.
6. Tilney LJ, Portnoy DA: Actin filaments and the growth, movement, and spread of the intracellular parasite, Listeria monocytogenes. J Cell Biol. 1989;109:1597-1608.
7. Domann E, Wehland J, Rohde M, Pistor S, Hartl M, et al.: A novel bacterial virulence gene in Listeria monocytogenes required for host cell microfilament interaction with homology to the proline-rich region of vinculin. EMBO J 1992;11:1981-1990.
8. Kocks C, Gouin E, Tabouret M, Berche P, Ohayon H, Cossart P: L monocytogenes-inducecl actin assembly requires the actA gene product, a surface protein. Cell 1992;68:521-531.
9. Rogers HW, Callery MP, Deck B, Unanue ER: Listeria monocytogenes induces apoptosis of infected hepatocytes. J Immunol 1996;156:679-684.
10. Villanueva MS, Beckers CJM, Pamer EG: Infection with Listeria monocytogenes impairs sialic acid addition to host cell glycoproteins. J Exp Med 1994;62:1881-1888.
11. Mackaness GB:Cellular resistance to infection. J Exp Med 1962;381-406
12. Miki K, Mackaness GB: The passive transfer of acquired resistance to Listeria monocytogenes. J Exp Med 1964;120:93-103.
13. Unanue ER: Studies in listeriosis show the strong symbiosis between the innate cellular system and the T-cell response. Immunol Rev 1997;158:11-25.
14. Unanue ER: Why listeriosis? A perspective on cellular immunity to infection. Immunol Rev 1997;158:5-11
15. Unanue E: Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance. Curr Opinion Immunol 1997;9:35-43.
16. Rogers HW, Unanue ER: Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice. Infect Immun 1993;91:5090-5096.
17. Conlan JW, North RJ: Neutrophil-mediated dissolution of infected host cells as a defense strategy against a facultative intracellular bacterium. J Exp Med 1991;174:744-744.
18. Czuprynski CJ, Henson PM, Campbell PA: Enhanced accumulation of inflammatory neutrophils and macrophages mediated by transfer of T cells from mice immunized with Listeria monocytogenes. J Immunol 1985;134:3449-3454.
19. Conlan JW, North RJ: Neutrophils are essential for early anti-Listeria defense in the liver, but not in the spleen or peritoneal cavity, as revealed by a granulocyte-depleting monoclonal antibody. J Exp Med 1994;179:259-268.
20. Dunn PL, North RJ: Early gamma interferon production by natural killer cells is important in defense against murine Listeriosis. Infect Immun 1991;59:2892-2900.
21. Hiromatsu K, Yoshikai Y, Matsuzaki G, Ohga S, Muramo K, Matsumo K, et al.: A protective role of γ/δ T cells in primary infection with Listeria monocytogenes in mice. J Exp Med 1992;175:49-56.
22. Bancroft GJ, Sheehan KC, Schreiber RD, Unanue ER: Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in SCID mice. J Immunol 1989;143:127-130.
23. Kaufmann SHE, Hug E, DeLibero G: Listeria monocytogenes reactive T lymphocyte clones with cytolytic activity against infected target cells. J Exp Med 1986; 164:363-368.
24. Harty JT, Schreiber RD, Bevan MJ: CD8 T cells can protect against an intracellular bacterium in an interferon gamma-independent fashion. Proc Natl Acad Sci USA 1992;89: 11,612-11,616.
25. Harty JT, Bevan MJ: Specific immunity to Listeria monocytogenes in the absence of INF gamma. Immunity 1995;3:109-118.
26. Ladel CH, Flesch IEF, Arnoldi J, Kaufmann SHE: Studies with MHC-deficient knock-out mice reveal impact of both MHC I- and MHC II-dependent T cell responses on Listeria monocytogenes infection. J Immunol 1994;153:3116-3122
27. Pamer EG, Harty JT, Bevan MJ: Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes. Nature 1991;353:852-855.
28. Pamer EG: Direct sequence identification and kinetic analysis of an MHC class I-restricted Listeria monocytogenes CTL epilope. J Immunol 1994;152:686-694.
29. Wuenscher MD, Kohler S, Bubert A, Gerike U, Goebel W: The iap gene of Listeria monocytogenes is essential for cell viability, and its gene product, p60, has bacteriolytic activity. J Bacteriol 1993;175:3491-3501.
30. Gentschev I, Sokolovic Z, Kohler S, Krohne G, Hof H, Wagner J, et al.: Identification of p60 antibodies in human sera and presentation of this Listerial antigen on the surface of attenuated Salmonellae by the HlyB-HlyD secretion system. Infect Immun 1992;60:5091-5098.
31. Sijts AJAM, Neisig A, Neefjes J, Pamer EG: Two Listeria monocytogenes CTL epitopes are processed from the same antigen with different efficiencies. J Immunol 1996;156:685-692.
32. Harty JT, Pamer EG: CD8 T lymphocytes specific fo the secreted p60 antigen protect against Listeria monocytogenes infection. J Immunol 1995;154:4642-4650.
33. Busch DH, Bouwer AGA, Hinrichs D, Pamer EG: A nonamer peptide derived from Listeria monocytogenes metalloprotease is presented to cytolytic T lymphocytes. Infect Immun 1997;65:5326-5329.
34. Domann E, Leimeister-Wachter M, Goebel W, Chakraborty T: Molecular cloning, sequencing and identification of a metalloprotease gene from Listeria monocytogenes that is species specific and physically linked to the listeriolysin gene. Infect Immun 1991;59:65-72.
35. Marquis H, Doshi V, Portnoy DA: The broad-range phospholipase C and a metalloprotease mediate listeriolysin O-independent escape of Listeria monocytogenes from a primary vacuole in human epithelial cells. Infect Immun 1995;63:4534-4534.
36. Villanueva MS, Fischer P, Feen K, Pamer EG: Efficiency of antigen processing: a quantitative analysis. Immunity 1994;I:479-489.
37. Hess J, Gentschev I, Miko D, Welzel M, Ladel C, Goebel W, et al.: Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis. Proc Natl Acad Sci USA 1996;93:1458-1463.
38. Hess J, Dietrich G, Gentschev I, Miko D, Goebel W, Kaufmann SHE: Protection against murine listeriosis by an attenuated recombinant Salmonella typhimurium vaccine strain that secretes the naturally somatic antigen superoxide dismutase. Infect Immun 1997;65:1286-1292.
39. Shen H, Miller JF, Fan X. Kolwyck D, Ahmed R, Harty JT: Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity. Cell 1998;92:535-545.
40. Pamer EG: Cell mediated immunity: The role of bacterial protein secretion. Curr Biol 1998;8:457-460.
41. Sijts AJA, Pamer EG: Enhanced intracellular dissociation of major histocompatibility complex class I-associated peptides: a mechanism for optimizing the spectrum of cell surface-presented cytotoxic tT lymphocyte epitopes. J Exp Med 1997;185:1403-1411.
42. Levitsky V, Zhang QJ, Levitskaya J, Kurilla MG, Masucci MG: Natural variants of the immunodominant HLA A11-restricted CTL epitope of the EBV nuclear antigen-4 are nonimmunogenic due to intracellular dissociation from MHC class I:peptide complexes. J Immunol 1997;159:5390-5390.
43. Villanueva MS, Sijts AJAM, Pamer EG: Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells. J Immunol 1995;155:5227-5233.
44. Hochstrasser M: Ubiquitin-dependent protein degradation. Annu Rev Genet 1997;30:405-439.
45. Ciechanover A: The ubiquitin- proteasome proteolytic pathway. Cell 1994;79:13-21.
46. Sijts AJAM, Pilip I, Pamer EG: The Listeria monocytogenes p60 protein is an N-end rule substrate in the cytosol of infected cells: implications for MHC class I antigen processing of bacterial proteins. J Biol Chem 1997;272:19,261-19,268.
47. Sijts AJAM, Villanueva MS, Pamer EG: CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen. J Immunol 1996;156:1497-1503.
48. Miyahira Y, Murata K, Rodriguez D, Rodriguez J, Esteban M, Rodriguez M, et al.: Quantification of antigen specific CD8+ T cells using an ELISPOT assay. J Immunol Methods 1995;181:45-54.
49. Vijh S, Pamer EG: Immunodominant and subdominant CTL responses to Listeria monocytogenes infection. J Immunol 1997;158:3366-3371.
50. Busch DH, Pamer EG: MHC class I/peptide stability: implications for immunodominance, in vitro proliferation and diversity of responding CTL J Immunol 1998;160:4441-4448.
51. Vijh S, Pilip IM, Pamer EG: Effect of antigen processing efficiency on in vivo T cell response magnitudes. J Immunol 1998;160:3977-3977.
52. Vijh S, Pilip IM, Pamer EG: Non-competitive expansion of CTL specific for different antigens during bacterial infection. Infect Immun 1998;67:1303-1309.
53. Altman JD, Moss PAH, Goulder PJR, Barouch DH, McHeyzer- Williams, Bell JI, et al.: Phenotypic analysis of antigen specific T lymphocytes. Science 1996;274:94-96.
54. Busch DH, Pilip IM, Vijh S, Pamer EG: Coordinate regulation of complex T cell populations responding to bacterial infection. Immunity 1998;8:353-362.
55. Busch DH, Pilip I, Pamer EG: Evolution of a complex T cell receptor repertoire during primary and recall bacterial infection. J Exp Med 1998;188:61-70.
56. Sourdive DJD, Murali-Krishna K, Altman JD, Zajac AJ, Whitmire JK, Pannetier C, et al.: Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to acute viral infection. J Exp Med 1998;188:71-82.
57. Callan MFC, Annels N, Steven N, Tan L, Wilson J, McMichael AJ, et al.: T cell selection during the evolution of CD8+ T cell memory in vivo. Eur. J Immunol 1998; 28:4382-4390.
58. Busch DH, Pamer EG: T cell affinity maturation by selective expansion following infection. J Exp Med 1999;189:701-709.
59. Kaufmann SHE, Rodewald HR, Hug E, Libero GD: Cloned Listeria monocytogenes specific non- MHC-restricted Lyt-2+ T cells with cytolytic and protective activity. J Immunol 1988;140:3179-3179.
60. Lukacs K, Kurlander RJ: MHC- unrestricted transfer of antilisterial immunity by freshly isolated immune CD8 spleen cells. J Immunol 1989;143:3731-3736.
61. Kurlander RJ, Shawar SM, Brown ML, Rich RR: Specialized role for a murine class I-b MHC molecule in prokaryotic host defenses. Science 1992;257:678-679.
62. Pamer EG, Wang CR, Flaherty L, Lindahl KF, Bevan MJ: H2-M3 presents a Listeria manocytogenes peptide to cytotoxic T lymphocytes. Cell 1992;70:215-223.
63. Shawar SM, Cook RG, Rodgers JR, Rich RR: Specialized functions of MHC class I molecules. I An N-formyl peptide receptor is required for construction of the class I antigen Mta. J Exp Med 1990;171:897-912.
64. Loveland BE, Wang CR, Yonekawa H, Hermel E, Lindahl KF: Maternally transmitted histocompatibility antigen of mice: a hydrophobic peptide of a mitochondrially encoded protein. Cell 1990;60:971-980.
65. Gulden PH, Fischer P, Sherman NE, Wang W, Engelhard V, Shabanowitz J, et al.: A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule. Immunity 1996;5:73-79.
66. Lenz LL, Dere B, Bevan MJ: Identification of an H2-M3-restricted Listeria epitope: Implications for antigen presentation by M3. Immunity 1996;5:63-72.
67. Princiotta MF, Lenz LL, Bevan MJ, Staerz UD: H2-M3 restricted presentation of a Listeria-derived leader peptide. J Exp Med 1998;187:1711-1720.