Enhancement of swine progenitor chimerism in mixed swine/human bone marrow cultures with swine cytokines

Experimental Hematology

Volumn 27, Issue 8, 1999, Pages 1330-1337

  Emery, David W ^a   Holley, Kristine ^a   Sachs, David H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Bone marrow; Culture; Cytokines; Swine; Xenogeneic

Indexed keywords

CYTOKINE; RECOMBINANT INTERLEUKIN 3; STEM CELL FACTOR;

ANIMAL CELL; ARTICLE; BONE MARROW CULTURE; BONE MARROW TRANSPLANTATION; CHIMERA; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOSTIMULATION; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; SWINE; XENOTRANSPLANTATION;

ANIMALS; BONE MARROW; BONE MARROW TRANSPLANTATION; CHIMERA; COCULTURE TECHNIQUES; GRAFT SURVIVAL; HUMANS; INTERLEUKIN-3; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; STEM CELL FACTOR; STROMAL CELLS; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 0032811258     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(99)00058-2     Document Type: Article

References (50)

1. Sachs D.H., Leight G., Cone J., Schwarz S., Stuart L., Rosenberg S. Transplantation in miniature swine. I. Fixation of the major histocompatibility complex. Transplantation. 22:1976;559.
2. Pennington L.R., Lunney J.K., Sachs D.H. Transplantation in miniature swine. VIII. Recombination within the major histocompatibility complex of miniature swine. Transplantation. 31:1981;66.
3. Sachs D.H. The pig as a potential xenograft donor. Vet Immunol Immunopathol. 43:1990;185.
4. Kirkman R.L. Of swine and men. organ physiology in different species Hardy M.A. Xenograft 25. 1989;125 Excerpta Medica, Amsterdam.
5. Reemtsma K., McCracken B.H., Schlegel J.V., Pearl M. Heterotransplantation of the kidney; two clinical experiences. Science. 143:1964;700.
6. Starzl T.E., Fung J., Tzakis A., Todo S., Demetris A.J., Marino I.R., Doyle H., Zeevi A., Warty V., Michaels M., Kusne S., Rudert W.A., Trucco M. Baboon-to-human liver transplantation. Lancet. 341:1993;65.
7. Lambrigts D., Sachs D.H., Cooper D.K.C. Discordant organ xenotransplantation in primates. Transplantation. 66:1998;547.
8. Sykes M., Strober S. Mechanisms of tolerance. Forman S.J., Blume K.G., Thomas E.D. Hematopoietic cell transplantation, vol II. 1999;Blackwell/Genne, Malden, MA. p. 264-286.Inc.
9. Sykes M., Sachs D.H. Mixed allogeneic chimerism as an approach to transplantation tolerance. Immunol Today. 9:1988;23.
10. Sykes M., Szot G.L., Swenson K.A., Pearson D.A. Induction of high levels of allogeneic hamatopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning. Nat Med. 3:1997;783.
11. Smith C.V., Nakajima K., Mixon A., Guzzetta P.C., Rosengard B.R., Fishbein J.M., Sachs D.H. Successful induction of long-term specific tolerance to fully allogeneic renal allografts in miniature swine. Transplantation. 53:1992;438.
12. Kawai T., Cosimi A.B., Colvin R.B., Powelson J., Eason J., Kozlowski T., Sykes M., Monroy R., Tanaka M., Sachs D.H. Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation. 59:1995;256.
13. Thomas A.W., Lu L., Wan Y., Qian S., Larsen C.P., Starzl T.E. Identification of donor-derived dendritic cell progenitors in bone marrow of spontaneously tolerant liver allograft recipients. Transplantation. 60:1995;1555.
14. Rugeles M.T., Aitouche A., Zeevi A., Fung J.J., Watkins S.C., Starzl T.E., Rao A.S. Evidence for the presence of multilineage chimerism and progenitors of donor dendritic cells in the peripheral blood of bone marrow-augmented organ transplantation recipients. Transplantation. 64:1997;735.
15. Ildstad S.T., Sachs D.H. Reconstitution with syngeneic plus allogeneic or xenogeneic bone marrow leads to specific acceptance of allografts or xenografts. Nature. 307:1984;168.
16. Kimikawa M., Sachs D.H., Colvin R.B., Bartholemew A., Kawai T., Cosimi A.B. Modification of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation. 64:1997;709.
17. Ramsdell F., Lantz T., Fowlkes B.J. A nondeletional mechanism of thymic self tolerance. Science. 246:1989;1038.
18. Marrack P., Lo D., Brinster R., Plmiter R., Burkly L., Flavell R.H., Kappler J. The effect of thymus environment on T cell development and tolerance. Cell. 53:1988;627.
19. Kappler J.W., Roehm N., Marrack P. T cell tolerance by clonal elimination in the thymus. Cell. 49:1987;280.
20. Oriol R., Ye Y., Koren E., Cooper D.K.C. Carbohydrate antigens of pig tissues reacting with human natural antibodies as potential targets for hyperacute vascular rejection in pig-to-man organ xenotransplantation. Transplantation. 56:1993;1433.
21. Sharabi Y., Aksentijevich I., Sundt T.M., Sachs D.H., Sykes M. Specific tolerance induction across a xenogeneic barrier. production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen J Exp Med. 172:1990;195.
22. Yang Y.G., deGoma E., Ohdan H., Bracy J.L., Xu Y., Iacomini J., Thall A.D., Sykes Tolerization of anti-Galα1-3Gal natural antibody-forming B cells by induction of mixed chimerism. J Exp Med. 187:1998;1335.
23. Bracy J.L., Sachs D.H., Iacomini J. Inhibition of xenoreactive natural antibody production by retroviral gene therapy. Science. 281:1998;1845.
24. Gritsch H.A., Glaser R.M., Emery D.W., Lee L.A., Smith C.V., Sablinski T., Arn J.S., Sachs D.H., Sykes M. The importance of nonimmune factors in reconstitution by discordant xenogeneic hematopoietic cells. Transplantation. 57:1994;906.
25. Lee L.A., Gritsch H.A., Arn J.S., Emery D.W., Glaser R.M., Sablinski T., Sachs D.H., Sykes M. Induction of tolerance to pig antigens in mice grafted with fetal pig thymus/liver grafts. Transplant Proc. 26:1994;1300.
26. Dick J.E., Lapidot T., Pflumio F. Transplantation of normal and leukemic human bone marrow into immune-deficient mice. development of animal models for human hematopoiesis Immunologic Rev. 124:1991;25.
27. Latinne D., Gianello P., Smith C.V., Nickeleit V., Kawai T., Beadle M., Haug C., Sykes M., Lebowitz E., Bazin H., Colvin R., Cosimi A.B., Sachs D.H. Xenotransplantation from pig to cynomolgus monkey. Approach toward tolerance induction Transplant Proc. 25:1993;336.
28. Tanaka M., Latinne D., Gianello P., Sablinski T., Lorf T., Bailin M., Nickeleit V., Colvin R., Lebowitz E., Sykes M., Cosimi A.B., Sachs D.H. Xenotransplantation from pig to cynomolgus monkey. The potential for overcoming xenograft rejection through induction of chimerism Transplant Proc. 26:1994;1326.
29. Lapidot T., Pflumio F., Doedens M., Murdoch B., Williams D.E., Dick J.E. Cytokine stimulation of multilineage hematopoiesis from immature human cells engrafted in SCID mice. Science. 255:1992;1137.
30. Nolta J.A., Hanley M.B., Kohn D.B. Sustained human hematopoiesis in immunodeficient mice by cotransplantation of marrow stroma expressing human interleukin-3. analysis of gene transduction of long-lived progenitors Blood. 83:1994;3041.
31. Yang Y.G., Sergio J.J., Swenson K., Glaser R.M., Monroy R., Sykes M. Donor-specific growth factors promote swine hematopoiesis in SCID mice. Xenotransplant. 3:1996;92.
32. Emery D.W., Sykes M., Sachs D.H., LeGuern C. Mixed swine/human long-term bone marrow cultures. Transplant Proc. 26:1994;1313.
33. Pennington L.R., Sakamoto K., Popitz-Bergez F.A., Pescovitz M.D., McDonough M.A., MacVittie T.J., Gress R.E., Sachs D.H. Bone marrow transplantation in miniature swine. I. Development of the model. Transplantation. 45:1988;21.
34. Eaves C.J., Eaves A.C. Erythropoietin (Ep) dose-response curves for three classes of erythroid progenitors in normal human marrow and in patients with polycythemia vera. Blood. 52:1978;1196.
35. Emery D.W., Sachs D.H., LeGuern C. Culture and characterization of hematopoietic progenitor cells from miniature swine. Exp Hematol. 24:1996;927.
36. Hawley R.J., Abraham S., Akiyoshi D.E., Arduini R., Denaro M., Dickerson M., Meshalum D.H., Monroy R.L., Schacter B.Z., Rosa M.D. Xenogeneic bone marrow transplantation. I. Cloning, expression, and species specificity of porcine IL-3 and granulocyte-macrophage colony-stimulating factor Xenotransplantation. 4:1997;103.
37. Giovino M.A., Hawley R.J., Dickerson M., Glaser R., Meshalum D.H., Arduini R., Rosa M.D., Monroy R.L. Xenogeneic bone marrow transplantation. II. Porcine-specific growth factors enhance porcine bone marrow engraftment in an in vitro primate microenvironment Xenotransplantation. 4:1997;112.
38. Eaves A.C., Cashman J.D., Gaboury L.A., Eaves C.J. Clinical significance of long-term cultures of myeloid blood cells. CRC Crit Rev Oncol Hematol. 7:1987;125.
39. McNiece I.K., Langley K.E., Zsebo K.M. Recombinant human stem cell factor synergises with GM-CSF, G-CSF, IL-3 and Epo to stimulate human progenitor cells of the myeloid and erythroid lineages. Exp Hematol. 19:1991;226.
40. McNiece I.K., Stewart F.M., Deacon D.M., Temeles D.S., Zsebo K.M., Clark S.C., Quesenberry P.J. Detection of a human CFC with high proliferative potential. Blood. 74:1989;609.
41. Ogawa M. Differentiation and proliferation of hematopoietic stem cells. Blood. 81:1993;2844.
42. Gritsch H.A., Sykes M. Host marrow has a competitive advantage which limits donor hematopoietic repopulation in mixed xenogeneic chimeras. Xenotransplant. 3:1996;312.
43. Dexter T.M., Allen T.D., Lajtha L.G. Conditions controlling the proliferation of haemopoietic stem cells in vitro. J Cell Physiol. 91:1977;335.
44. Schuening F.G., Storb R., Meyer J., Goehle S. Long-term culture of canine bone marrow cells. Exp Hematol. 17:1989;411.
45. Cohen D.R., Hapel A.J., Young I.G. Cloning and expression of the rat interleukin-3 gene. Nucleic Acids Res. 14:1986;3641.
46. Bodine D.M., Orlic D., Birkett N.C., Seidel N.E., Zsebo K.M. Stem cell factor increases colony-forming unit-spleen number in vitro in synergy with interleukin-6, and in vivo in Sl/Sld mice as a single factor. Blood. 79:1992;913.
47. Andrews R.G., Bartelmez S.H., Knitter G.H., Myerson D., Bernstein I.D., Appelbaum F.R., Zsebo K.M. A c-kit ligand, recombinant human stem cell factor, mediates reversible expansion of multiple CD34+ colony-forming cell types in blood and marrow of baboons. Blood. 80:1992;920.
48. Yonemura Y., Ku H., Hirayama F., Souza L., Ogawa M. Interleukin 3 or interleukin 1 abrogates the reconstituting ability of hematopoietic stem cells. Proc Natl Acad Sci. 93:1996;4040.
49. Sablinski T., Gianello P., Bailin M., Bergen K.S., Emery D.W., Fishman J.A., Foley A., Hatch T., Hawley B., Kozlowski T., Lorf T., Meehan S., Monroy R., Powelson J.A., Colvin R., Cosimi A.B., Sachs D.H. Pig to monkey bone marrow and kidney xenotransplantation. Surgery. 121:1997;281.
50. Sablinski T., Emery D.W., Monroy R., Hawley R.J., Xu Y., Gianello P.R., Lorf T., Kozlowski T., Bailin M., Cooper D.K.C., Cosimi A.B., Sachs D.H. Long-term discordant xenogeneic (porcine-to-primate) bone marrow engraftment in a monkey treated with porcine-specific growth factors. Transplantation. 67:1999;972.