Genetic evolutionary staging of early non-small cell lung cancer: The p53 → Her-2/neu → ras sequence

Journal of Thoracic and Cardiovascular Surgery

Volumn 118, Issue 2, 1999, Pages 259-269

  Shackney, S E ^a   Smith, C A ^a   Pollice, A ^a   Levitt, M ^a   Magovern, J A ^a   Wiechmann, R J ^a   Silverman, J ^a   Sweeney, L ^a   Landreneau, R J ^a   Vallieres, E ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ADVANCED CANCER; ARTICLE; CELL SUBPOPULATION; DNA CONTENT; FLOW CYTOMETRY; GENE TARGETING; GENETIC ANALYSIS; HIGH RISK POPULATION; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; MOLECULAR GENETICS; ONCOGENE NEU; ONCOGENE RAS; PLOIDY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0032809236     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5223(99)70216-3     Document Type: Article

References (24)

1. P Nowell The clonal evolution of tumor cell populations Science 194 1976 23 28
2. S Shackney T Shankey Common patterns of genetic evolution in human solid tumors Cytometry 29 1997 1 27
3. S Shackney A Pollice C Smith L Janocko L Sweeney K Brown Intracellular coexpression of epidermal growth factor receptor, Her-2/neu, and p21 ras in human breast cancers: evidence for the existence of distinctive patterns of genetic evolution that are common to tumors from different patients Clin Cancer Res 4 1998 913 918
4. S Shackney C Smith A Pollice L Janocko S Singh D Groft Preferred genetic evolutionary sequences in human breast cancer: a case study Cytometry 21 1995 6 13
5. CF Mountain Revisions in the International System for Staging Lung Cancer Chest 111 1997 1710 1717
6. AA Pollice JP McCoy Jr SE Shackney CA Smith J Agarwal DR Burholt Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins Cytometry 13 1992 432 444
7. S Bodner J Minna S Jensen D D’Amico D Carbone T Mitsudomi Expression of mutant p53 proteins in lung cancer correlates with the class of gene mutation Oncogene 7 1992 743 749
8. A Levine p53, the cellular gatekeeper for growth and division Cell 88 1997 323 331
9. V Sundaresan P Ganly P Hasleton R Rudd G Sinha N Bleehen p53 and chromosome 3 abnormalities, characteristic of malignant lung tumors, are detectable in preinvasive lesions of the bronchus Oncogene 7 1992 1989 1997
10. G Sozzi M Miozzo R Donghi S Pilotti C Caraini U Pastorino Deletions of 17p and p53 mutations in preneoplastic lesions of the lung Cancer Res 52 1992 6079 6082
11. W Bennett T Colby W Travis A Borkowski R Jones D Lane p53 protein accumulates frequently in early bronchial neoplasia Cancer Res 53 1993 4817 4822
12. Z-H Li J Zheng L Weiss D Shibata c-K- ras and p53 mutations occur very early in adenocarcinoma of the lung Am J Pathol 144 1994 303 309
13. K Sugio Y Kishimoto A Virmani J Hung A Gazdar K- ras mutations are a relatively late event in the pathogenesis of lung carcinomas Cancer Res 54 1994 5811 5815
14. H Dosaka M Harada N Kuzumaki H Kobayashi H Miyamoto Y Kawakami The relationship of clinical classification to ras p21 expression in human non–small cell lung cancer Oncology 45 1988 396 400
15. C Finlay P Hinds A Levine The p53 proto-oncogene can act as a suppressor of transformation Cell 57 1989 1083 1093
16. Y Haupt R Maya A Kazaz M Oren Mdm2 promotes the rapid degradation of p53 Nature 387 1997 296 299
17. M Kubbutat S Jones K Vousden Regulation of p53 stability by Mdm2 Nature 387 1997 299 303
18. Arf, interacts with MDM2 and neutralizes MDM2’s inhibition of p53 Cell 92 1998 713 723
19. J Iglehart M Kraus B Langton G Huper B Kerns J Marks Increased ErbB-2 gene copies and expression in multiple stages of breast cancer Cancer Res 50 1990 6701 6707
20. D Ciocca F Fujimura A Tandon G Clark C Mark G-J Lee-Chen Correlation of Her-2/neu amplification with expression and with other prognostic factors in 1103 breast cancers J Natl Cancer Inst 84 1992 1279 1281
21. M Press M Pike V Chazin G Hung U JA M Markowicz Her-2/neu expression in node-negative breast cancer: direct tissue quantitation by computerized image analysis and association of overexpression with increased risk of recurrent disease Cancer Res 53 1993 4960 4970
22. K Robertson J Reeves G Smith W Keith B Ozanne T Cooke Quantitative estimation of epidermal growth factor receptor and c-ErbB-2 in human breast cancer Cancer Res 56 1996 3823 3830
23. P Schneider M-C Hung S Chiocca J Manning X Zhao K Fang Differential expression of the c-ErbB-2 gene in human small cell and non–small cell lung cancer Cancer Res 49 1989 4968 4971
24. S Shackney A Pollice C Smith L Alston S Singh L Janocko The accumulation of multiple genetic abnormalities in individual tumor cells in human breast cancers: clinical prognostic implications Cancer J 2 1996 105 114