The production of nitric oxide and tumor necrosis factor by murine macrophages infected with mycobacterial strains differing by hemolytic activity

Microbiology and Immunology

Volumn 43, Issue 7, 1999, Pages 637-644

  Rudnicka, Wiesława ^a   Brzychcy, Marzena ^a   Klink, Magdalena ^b   Lopez, Arley Gomez ^c   Fonteyne, Pierre Alain ^c   Rüsch Gerdes, Sabine ^d   Rózalska, Barbara ^a  

^a UNIVERSITY OF LODZ   (Poland)

^b POLISH ACADEMY OF SCIENCES   (Poland)

^c INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^d Natl Ref Ctr Mycobacterium F   (Germany)

Author keywords

Hemolysis; Macrophages; Mycobacteria; Nitric oxide; TNF

Indexed keywords

NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BACTERIUM ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HEMOLYSIS; MONONUCLEAR PHAGOCYTE; MOUSE; MYCOBACTERIOSIS; MYCOBACTERIUM AVIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PERITONEUM MACROPHAGE;

ANIMALIA; BACILLI; BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MURINAE; MYCOBACTERIUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 0032808840     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.1999.tb02451.x     Document Type: Article

References (60)

1. Adams, L.B., Franzblau, S.G., Vavrin, Z., Hibbs, J.B., and Krahenbuhl, J.L. 1991. L-Arginine-dependent macrophage effector function inhibit metabolic activity of Mycobacterium leprae. J. Immunol. 147: 1642-1648.
2. Bellamy, R., Ruwende, C., Corrah, T., McAdam, K.P.W.J., Whittle, H.C., and Hill, A.V.S. 1998. Variations in the NRAMPI gene and susceptibility to tuberculosis in West Africans. N. Engl. J. Med. 338: 640-644.
3. Bermundez, L.E.M., Wu, M., Petrofsky, M., and Young, L.S. 1992. Interleukin-6 antagonizes tumor necrosis factor-mediated mycobacteriostatic and mycobactericidal activities in macrophages. Infect. Immun. 60: 4245-4252.
4. Bermundez, L.E.M. 1993. Differential mechanisms of intracellular killing of Mycobacterium avium and Listeria monocytogenes by activated human and murine macrophages: the role of nitric oxide. Cell. Exp. Immunol. 91: 277-281.
5. Bermundez, L.E.M., and Young, L.S. 1988. Tumor necrosis factor, alone or in combination with IL-2, but not IFN-γ, is associated with macrophage killing of Mycobacterium avium complex. J. Immunol. 140: 3006-3013.
6. Bradbury, M.G., and Moreno, M.R.C. 1993. Effect of lipoarabinomannan and mycobacteria on tumor necrosis factor production by different populations of murine macrophages. Clin. Exp. Immunol. 94: 57-63.
7. Britton, W.J., Meadows, N., Rathjen, D.A., Roach, D.R., and Briscoe, H. 1998. A tumor necrosis factor mimetic peptide activates a murine macrophage cell line to inhibit mycobacterial growth in a nitric oxide-dependent fashion. Infect. Immun. 66: 2122-2127.
8. Brzychcy, M., Klink, M., Tchórzewski, H., and Rudnicka, W. 1997. Listeria monocytogenes infection in mice treated with pentoxifylline. Zbl. Bakt. 285: 491-500.
9. Brzychcy, M., Andrzejczyk, Z., Zalewska, N., Zwolska, Z., and Rudnicka, W. 1997. Haemolytic activity of Mycobacterium spp. Acta Microbiol. Polon. 47: 371-378.
10. Brzychcy, M., Zwolska, Z., Andrzejczyk, Z., and Rudnicka, W. 1998. Cellular reaction to Mycobacterium avium complex (MAC) clinical isolates differing in hemolytic activity and virulence for C57B1/6 mice. Microbiol. Immunol. 42: 357-363.
11. Chan, J., Xing, V., Magliozzo, R., and Bloom, B.R. 1992. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated macrophages. J. Exp. Med. 175: 1111-1122.
12. Chatterjee, D., Roberts, A.D., Lowell, K., Brennan, P.J., and Orme, I.M. 1992. Structural basis of capacity of lipoarabinomannan to induce secretion of tumor necrosis factor. Infect. Immun. 60: 1249-1253.
13. Collins, F.M. 1993. Tuberculosis: the return of an old enemy. Crit. Rev. Microbiol. 19: 1-16.
14. Davies, P.D.O., De Cock, K.M., Leese, J., and Moore-Gillon, J. 1996. Tuberculosis 2000. J. Roy. Soc. Med. 89: 431-435.
15. Denis, M. 1991. Tumor necrosis factor and granulocyte macrophage-colony stimulating factor stimulate human macrophages to restrict growth of virulent Mycobacterium avium and to kill avirulent M. avium: killing effector mechanisms depends on the generation of reactive nitrogen intermediates. J. Leukoc. Biol. 49: 380-387.
16. Deshpande, R.G., Kham, M.B., Bhat, D.A., and Navalkar, R.G. 1997. Isolation of a contact-dependent haemolysin from Mycobacterium tuberculosis. J. Med. Microbiol. 46: 233-238.
17. Deshpande, R.G., Khan, M.B., Bhat, D.A., and Navalkar, R.G. 1998. Haemolysin from Mycobacterium avium complex isolates from AIDS patients. J. Med. Microbiol. 47: 365-367.
18. Ding, A.H., Nathan, C.F., and Stuehr, D.J. 1988. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. J. Immunol. 141: 2407-2412.
19. Doherty, T.M., and Sher, A. 1997. Defects in cell-mediated immunity affect chronic, but not innate, resistance of mice to Mycobacterium avium infection. J. Immunol. 158: 4822-4831.
20. Doi, T., Ando, M., Akaike, T., Sato, K., and Maeda, H. 1993. Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis. Infect. Immun. 61: 1980-1989.
21. Eaton, T., Falkinham, J.O., and von Reyn, C.F. 1995. Recovery of Mycobacterium avium from cigarettes. J. Clin. Microbiol. 33: 2757-2758.
22. Eriks, I.S., and Emerson, C.L. 1997. Temporal effect of tumor necrosis factor alpha on murine macrophages infected with Mycobacterium avium. Infect. Immun. 65: 2100-2106.
23. Fischer, L.J., Quinn, F.D., White, E.H., and King, C.H. 1996. Intracellular growth and cytotoxicity of Mycobacterium haemophilum in a human epithelial cell line (Hec-1-B). Infect. Immun. 64: 269-276.
24. Flesch, I.E.A., and Kaufmann, S.H.E. 1990. Activation of tuberculostatic macrophage functions by gamma interferon, interleukin-4, and tumor necrosis factor. Infect. Immun. 58: 2675-2677.
25. Fonteyne, P.A., Kunze, Z.M., De Beenhouwer, H., Dumonceau, J.M., Dawson, D.J., McFadden, J.J., and Portaels, F. 1997. Characterization of Mycobacterium avium complex related mycobacteria isolated from an African environment and patients with AIDS. Trop. Med. Int. Health 2: 200-207.
26. Gato, Y., Buschman, E., and Skamene, E. 1989. Regulation of host resistance to Mycobacterium intracellulare in vivo and in vitro by the Bcg gene. Immunogenetics 30: 218-221.
27. Groves, M.J. 1997. BCG: the past, present and future of a tuberculosis vaccine. J. Pharm. Pharmacol. 49 (Suppl. 1): 7-15.
28. Hibbs, J.B., Taintor, R.R., Vavrin, Z., and Rachlin, E.M. 1988. Nitric oxide: a cytotoxic activated macrophage effector molecule. Biochem. Biophys. Res. Commun. 157: 87-94.
29. Horsburgh, C.R. 1997. Epidemiology of Mycobacterium avium complex disease. Am. J. Med. 102: 11-15.
30. Ichiyama, S., Shimokata, K., and Tsukamura, M. 1988. The isolation of Mycobacterium avium complex from soil, water, dust and cigarettes. Microbiol. Immunol. 32: 733-739.
31. Inderlied, C.B., Kemper, C.A., and Bermudez, L.E.M. 1993. The Mycobacterium avium complex. Clin. Microbiol. Rev. 6: 266-310.
32. King, C.H., Mundayoor, S., Crawford, J.T., and Shinnick, T.M. 1993. Expression of contact-dependent cytolytic activity by Mycobacterium tuberculosis and isolation of the genomic locus that encodes the activity. Infect. Immun. 61: 2708-2712.
33. MacMicking, J.D., North, R.J., LaCourse, R., Mudgett, J.S., Shah, S.K., and Nathan, C.F. 1997. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc. Natl. Acad. Sci. U.S.A. 94: 5243-5248.
34. Mauel, J., Ransijn, A., and Buchmuller-Rouiller, Y. 1991. Killing of Leishmania parasites in activated murine macrophages is based on an L-arginine-dependent process that produces nitrogen derivatives. J. Leukoc. Biol. 49: 73-82.
35. McDonough, K.A., Kress, Y., and Bloom, B.R. 1993. Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages. Infect. Immun. 61: 2763-2773.
36. Medina, E., and North, R.J. 1996. Evidence inconsistent with a role for the Bcg gene (NrampI) in resistance of mice to infection with virulent Mycobacterium tuberculosis. J. Exp. Med. 183: 1045-1051.
37. Mehta, P.K., King, C.H., White, E.H., Murtagh, J.J., and Quinn, F.D. 1996. Comparison of in vitro models for the study of Mycobacterium tuberculosis invasion and intracellular replication. Infect. Immun. 64: 2673-2679.
38. Morimoto, A., Sakata, Y., Watanabe, T., and Murakami, N. 1989. Characteristics of fever and acute-phase response induced in rabbits by IL-1 and TNF. Am. J. Physiol. 256: R35-R41.
39. Munder, M., Mallo, M., Eichmann, K., and Modelell, M. 1998. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J. Exp. Med. 187: 2103-2108.
40. Myrvik, Q.N., Leake, E.S., and Wright, M.J. 1984. Disruption of phagosomal membranes of normal alveolar macrophages by the H37Rv strain of Mycobacterium tuberculosis: a correlate of virulence. Am. Rev. Respir. Dis. 129: 322-328.
41. Nathan, C. 1997. Inducible nitric oxide synthase: what difference does it make? J. Clin. Invest. 100: 2417-2423.
42. North, R.J., and Medina, E. 1996. Significance of the antimicrobial resistance gene, Nramp I, in resistance to virulent Mycobacterium tuberculosis infection. Res. Immunol. 147: 493-499.
43. Olivier, M., Cook, P., Desanctis, J., Hel, Z., Wojciechowski, W., Reiner, N.E., Skamene, E., and Radzioch, D. 1998. Phenotypic difference Bcg(r) and Bcg(s) macrophages is related to differences in protein-kinase-C-depending signalling. Eur. J. Biochem. 251: 734-743.
44. 3 metabolites and tumor necrosis factor in the pathogenesis of tuberculosis. Immunology 62: 229-234.
45. Różalska, B., Długońska, H., Ljungh, A., Paziak-Domańska, B., Burow, A., and Rudnicka, W. 1996. The cells of monocyte-macrophage lineage in mice with the 2-month-polyethylene implantation. Immunol. Lett. 49: 99-103.
46. Rüsch-Gerdes, S. 1995. Diagnosis of tuberculosis. Internist 36: 957-960.
47. Sarmento, A.M., and Appelberg, R. 1995. Relationship between virulence of Mycobacterium avium strains and induction of tumor necrosis factor alpha production in infected mice and in in vitro-cultured mouse macrophages. Infect. Immun. 63: 3759-3764.
48. Sarmento, A., and Appelberg, R. 1996. Involvement of reactive oxygen intermediates in tumor necrosis factor alpha-dependent bacteriostasis of Mycobacterium avium. Infect. Immun. 64: 3224-3230.
49. Schulze-Röbbecke, R., Feldmann, C., Fischeder, R., Janning, B., Exner, M., and Wahl, G. 1995. Dental units: an environmental study of sources of potentially pathogenic mycobacteria. Tuber. Lung Dis. 76: 318-323.
50. Silver, R.F., Li, Q., and Ellner, J.J. 1998. Expression of virulence of Mycobacterium tuberculosis within human monocytes: virulence correlates with intracellular growth and induction of tumor necrosis factor alpha but not with evasion of lymphocyte-dependent monocyte effector functions. Infect. Immun. 66: 1190-1199.
51. + T cells in purified protein derivative-positive, but not in purified protein derivative-negative subjects. J. Immunol. 160: 2408-2417.
52. Smith, D., Hansch, H., Bancroft, G., and Ehlers, S. 1997. T-cell independent granuloma formation in response to Mycobacterium avium: role of tumor necrosis factor-alpha and interferon-gamma. Immunology 92: 413-421.
53. Sugita, Y., Miyamoto, M., Koseki, M., Ishii, N., and Nakajima, H. 1997. Suppression of tumor necrosis factor-α expression in leprosy skin lesions during treatment for leprosy. Br. J. Dermatol. 136: 393-397.
54. Takashima, T., Ueta, C., Tsuyuguchi, I., and Kishimoto, S. 1990. Production of tumor necrosis factor alpha by monocytes from patients with pulmonary tuberculosis. Infect. Immun. 58: 3286-3292.
55. Takeichi, O., Saito, I., Okamoto, Y., Tsurumachi, T., and Saito, T. 1998. Cytokine regulation on the synthesis of nitric oxide in vivo by chronically infected human polymorphonuclear leukocytes. Immunology 93: 275-280.
56. Tomioka, H., Sato, K., Sano, C., Akai, T., Shimizu, T., Kajitani, H., and Saito, H. 1997. Effector molecules of the host defence mechanisms against Mycobacterium avium complex: the evidence showing that reactive oxygen intermediates, reactive nitrogen intermediates, and free fatty acids each alone are not decisive in expression of macrophage antimicrobial activity against the parasites. Clin. Exp. Immunol. 109: 248-254.
57. Toossi, Z. 1996. Cytokine circuits in tuberculosis. Infect. Agents Dis. 5: 98-107.
58. Vidal, S., Gros, P., and Skamene, E. 1995. Natural resistance to infection with intracellular parasites: molecular genetics identifies Nramp I as the Bcg/Ity/Lsh locus. J. Leukoc. Biol. 58: 382-390.
59. Wren, B.W., Stabler, R.A., Das, S.S., Butcher, P.D., Mangan, J.A., Clarke, J.D., Casali, N., Parish, T., and Stoker, N.G. 1998. Characterization of a haemolysin from Mycobacterium tuberculosis with homology to a virulence factor of Serpulina hyodysenteriae. Microbiology 144: 1205-1211.
60. Xu, D.L., Goto, Y., Endo, F., Amoako, K.K., and Shinjo, T. 1997. The effect of Bcg gene on antigen presentation of spleen adherent cells and peritoneal macrophages from Mycobacterium bovis BCG-infected Bcg(s) and Bcg(r) mice. Vet. Microbiol. 59: 67-78.