Effects of lesions to the hippocampus on contextual fear: Evidence for a disruption of freezing and avoidance behavior but not context conditioning

Behavioral Neuroscience

Volumn 113, Issue 3, 1999, Pages 507-522

  Gisquet Verrier, Pascale ^a   Dutrieux, Gérard ^a   Richer, Paulette ^a   Doyère, Valérie ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; CONDITIONING; CONTROLLED STUDY; FEAR; FREEZING; HIPPOCAMPUS; MALE; NONHUMAN; RAT; SHOCK;

ANIMALS; AVOIDANCE LEARNING; CONDITIONING, CLASSICAL; CONDITIONING, OPERANT; ELECTROSHOCK; EXCITATORY AMINO ACID AGONISTS; FEAR; HIPPOCAMPUS; IBOTENIC ACID; MALE; NERVE NET; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0032806983     PISSN: 07357044     EISSN: None     Source Type: Journal    
DOI: 10.1037/0735-7044.113.3.507     Document Type: Article

References (45)

1. Balsam, P. D., & Tomie, A. (1985). Context and learning. Hillsdale, NJ: Erlbaum.
2. Blanchard, D. C., Blanchard, R. J., Lee, E. M. C., & Fukunage, K. K. (1977). Movement arrest and the hippocampus. Physiological Psychology, 5, 331-335.
3. Blanchard, R. J., & Blanchard, D. C. (1969a). Crouching as an index of fear. Journal of Comparative and Physiological Psychology, 67, 370-375.
4. Blanchard, R. J., & Blanchard, D. C. (1969b). Passive and active reactions to fear-eliciting stimuli. Journal of Comparative and Physiological Psychology, 68, 129-135.
5. Diamond, D. M., Fleshner, M., Ingersoll, N., & Rose, G. M. (1996). Psychological stress impairs spatial working memory: Relevance to electrophysiological studies of hippocampal function. Behavioral Neuroscience, 110, 661-672.
6. Frankland, P. W., Cestari, V., Filipkowski, R. K., McDonald, R. J., & Silva, A. J. (1998). The dorsal hippocampus is essential for context discrimination but not for contextual conditioning. Behavioral Neuroscience, 112, 863-874.
7. Garrud, P., Rawlins, J. N. P., Mackintosh, N. J., Goodall, G., Cotton, M. M., & Feldon, J. (1984). Successful overshadowing and blocking in hippocampectomized rats. Behavioural Brain Research, 12, 39-53.
8. Gisquet-Verrier, P., & Doyère, V. (1997). Lesions to the hippocampus in rats do not affect conditioning to contextual cues in classical fear conditioning. Society for Neuroscience Abstracts, 23, 1609.
9. Gisquet-Verrier, P., & El Massioui, N. (1997). Selective hippocampal lesions in rats disrupt acquisition and retention of a positive patterning discrimination. Physiology and Behavior, 61, 577-589.
10. Gisquet-Verrier, P., & Schenk, F. (1994). Selective hippocampal lesions in rats do not affect retrieval processes promoted by prior cuing with a conditioned stimulus or the context. Psychobiology, 22, 289-303.
11. Good, M., & Honey, R. C. (1991). Conditioning and contextual retrieval in hippocampal rats. Behavioral Neuroscience, 105, 499-509.
12. Good, M., & Honey, R. C. (1997). Dissociable effects of selective lesions to hippocampal subsystems on exploratory behavior, contextual learning, and spatial learning. Behavioral Neuroscience, 111, 487-493.
13. Hall, G., Purves, D., & Bonardi, C. (1996). Contextual control of conditioned responding in rats with dorsal hippocampal lesions. Behavioral Neuroscience, 110, 933-945.
14. Hirsh, R. (1974). The hippocampus and contextual retrieval of information from memory: A theory. Behavioral Biology, 12, 421-444.
15. Hirsh, R., Holt, L., & Mosseri, A. (1978). Hippocampal mossy fibers, motivational states, and contextual retrieval. Experimental Neurology, 62, 68-79.
16. Honey, R. C., & Good, M. (1993). Selective hippocampal lesions abolish the contextual specificity of latent inhibition and conditioning. Behavioral Neuroscience, 107, 23-33.
17. Hsiao, S., & Isaacson, R. L. (1971). Learning of food and water position by hippocampus damaged rats. Physiology and Behavior, 6, 81-83.
18. Hughey, D. J., & Koppenaal, R. J. (1987). Hippocampal lesions in rats alter learning about intramaze cues. Behavioral Neuroscience, 101, 634-643.
19. Hull, C. L. (1943). Principles of behavior. New York: Appleton-Century-Crofts.
20. Jarrard, L. E. (1989). On the use of ibotenic acid to lesion selectively different components of the hippocampal formation. Journal of Neuroscience Methods, 29, 251-259.
21. Jay, T. M., & Witter, N. P. (1991). Distribution of hippocampal CA1 and subicular efferents in the prefrontal cortex of the rats studied by means of anterograge transport of Phaseolus vulgaris-leucoagglutinin. Journal of Comparative Neurology, 313, 574-586.
22. Kim, J. J., & Fanselow, M. S. (1992, May). Modality-specific retrograde amnesia of fear. Science, 256, 675-677.
23. Kim, J. J., Rison, R. A., & Fanselow, M. S. (1993). Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear. Behavioral Neuroscience, 107, 1093-1098.
24. Lovely, R. H., Grossen, N. E., Moot, S. A., Bauer, R. H., & Peterson, J. J. (1971). Hippocampal lesions and inhibition of avoidance behavior. Journal of Comparative and Physiological Psychology, 77, 345-352.
25. Mackintosh, N. J. (1974). The psychology of animal learning. London: Academic Press.
26. Maren, S., Aharonov, G., & Fanselow, M. S. (1997). Neurotoxic lesions of the dorsal hippocampus and Pavlovian fear conditioning in rats. Behavioural Brain Research, 88, 261-274.
27. McNish, K. A., Gewirtz, J. C., & Davis, M. (1997). Evidence of contextual fear after lesions of the hippocampus: A disruption of freezing but not fear-potentiated startle. Journal of Neuroscience, 17, 9353-9360.
28. Nadel, L., & Willner, J. (1980). Context and conditioning: A place for space. Physiological Psychology, 8, 218-228.
29. Pavlov, I. P. (1927). Conditioned reflexes. Oxford, England: Oxford University Press.
30. Paxinos, G., & Watson, C. (1986). The rat brain in stereotaxic coordinates. London: Academic Press.
31. Penick, S., & Solomon, P. R. (1991). Hippocampus, context, and conditioning. Behavioral Neuroscience, 105, 611-617.
32. Phillips, R. G., & LeDoux, J. E. (1992). Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behavioral Neuroscience, 106, 274-285.
33. Phillips, R. G., & LeDoux, J. E. (1994). Lesions of the dorsal hippocampal formation interfere with background but not foreground contextual fear conditioning. Learning & Memory, 1, 34-44.
34. Phillips, R. G., & LeDoux, J. E. (1995). Lesions of the fornix but not the entorhinal or perirhinal cortex interfere with contextual fear conditioning. Journal of Neuroscience, 15, 5308-5315.
35. Rescorla, R. A., & Wagner, A. R. (1972). A theory of Pavlovian conditioning: Variations in the effectiveness of reinforcement and nonreinforcement. In A. H. Black & W. F. Prokasy (Eds.), Classical conditioning II: Current research and theory (pp. 64-99). New York: Appleton-Century-Crofts.
36. Rickert, E. J., Bennett, T. L., Lane, P., & French, J. (1978). Hippocampectomy and attenuation of blocking. Behavioral Biology, 22, 147-160.
37. Selden, N. R. W., Everitt, B. J., Jarrard, L. E., & Robbins, T. W. (1991). Complementary roles for the amygdala and hippocampus in aversive conditioning to explicit and contextual cues. Neuroscience, 42, 335-350.
38. Solomon, P. R. (1979). Temporal versus spatial information processing theories of hippocampal function. Psychological Bulletin, 86, 1272-1279.
39. Squire, L. R. (1987). Memory and brain. New York: Oxford University Press.
40. Sutherland, R. J., & Rudy, J. W. (1989). Configural association theory: The role of the hippocampal formation in learning, memory, and amnesia. Psychobiology, 17, 129-144.
41. Whishaw, I. Q., & Tomie, J. (1991). Acquisition and retention by rats of simple, conditional, and configural tasks using tactile and olfactory cues: Implication for hippocampal function. Behavioral Neuroscience, 105, 787-797.
42. Wilson, A., Brooks, D. C., & Bouton, M. E. (1995). The role of the rat hippocampal system in several effects of context in extinction. Behavioral Neuroscience, 109, 828-836.
43. Winocur, G. (1997). Hippocampal lesions alter conditioning to conditional and contextual stimuli. Behavioural Brain Research, 111, 712-726.
44. Winocur, G., & Olds, J. (1978). Effects of context manipulation on memory and reversal learning in rats with hippocampal lesions. Journal of Comparative and Physiological Psychology, 92, 312-321.
45. Winocur, G., Rawlins, J. N. P., & Gray, J. A. (1987). The hippocampus and conditioning to contextual cues. Behavioral Neuroscience, 101, 617-625.