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Volumn 9, Issue 3, 1999, Pages 327-332

Low frequency of CYP2A6 gene polymorphism as revealed by a one-step polymerase chain reaction method

Author keywords

Cytochrome P450; DNA sequencing; Genetic polymorphism restriction fragment length polymorphism

Indexed keywords

CYTOCHROME P450; RESTRICTION ENDONUCLEASE;

EID: 0032805514     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199906000-00007     Document Type: Article
Times cited : (54)

References (17)
  • 1
    • 0017148259 scopus 로고
    • A general method for isolation of high molecular weight DNA from eukaryotes
    • Blin N, Stafford DW. A general method for isolation of high molecular weight DNA from eukaryotes. Nucleic Acids Res 1976; 3:2303-2308.
    • (1976) Nucleic Acids Res , vol.3 , pp. 2303-2308
    • Blin, N.1    Stafford, D.W.2
  • 2
    • 0025848338 scopus 로고
    • A tobacco smoke-denied nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450206
    • Crespi CL, Penman BW, Gelboin HV, Gonzalez FJ. A tobacco smoke-denied nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450206. Carcinogenesis 1991; 12: 1197-1201.
    • (1991) Carcinogenesis , vol.12 , pp. 1197-1201
    • Crespi, C.L.1    Penman, B.W.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 3
    • 0009610299 scopus 로고
    • Purification and characterization of two unique forms of cytochrome P-450 from rabbit nasal microsomes
    • Ding X, Coon MJ. Purification and characterization of two unique forms of cytochrome P-450 from rabbit nasal microsomes. Biochemistry 1988; 29:1322-1329.
    • (1988) Biochemistry , vol.29 , pp. 1322-1329
    • Ding, X.1    Coon, M.J.2
  • 4
    • 0029099107 scopus 로고
    • A genetic polymorphism in coumarin 7-hydroxylation: Sequence of the human CYP2A genes and identification of variant CYP2A6 alleles
    • Fernandez-Salguero P, Hoffman SMG, Cholerton S, Mohrenweiser H, Raunio H, Rautio A, et al. A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. Am J Hum Genet 1995; 57:651-660.
    • (1995) Am J Hum Genet , vol.57 , pp. 651-660
    • Fernandez-Salguero, P.1    Hoffman, S.M.G.2    Cholerton, S.3    Mohrenweiser, H.4    Raunio, H.5    Rautio, A.6
  • 6
    • 0030697098 scopus 로고    scopus 로고
    • A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin
    • Hadidi H, Zahlsen K, Idle JR, Cholerton S. A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin. Food Chem Toxicol 1997; 35:903-907.
    • (1997) Food Chem Toxicol , vol.35 , pp. 903-907
    • Hadidi, H.1    Zahlsen, K.2    Idle, J.R.3    Cholerton, S.4
  • 7
    • 0031914368 scopus 로고    scopus 로고
    • Differential amplification kinetics for point mutation analysis by PCR
    • Kaltenbock B, Schneider R. Differential amplification kinetics for point mutation analysis by PCR. BioTechniques 1998; 24:202-206.
    • (1998) BioTechniques , vol.24 , pp. 202-206
    • Kaltenbock, B.1    Schneider, R.2
  • 8
    • 0030885491 scopus 로고    scopus 로고
    • A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes
    • Messina ES, Tyndale RF, Sellers EM. A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes. J Pharmacol Exp Ther 1997; 282:1608-1614.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1608-1614
    • Messina, E.S.1    Tyndale, R.F.2    Sellers, E.M.3
  • 9
    • 0025214234 scopus 로고
    • Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity
    • Miles JS, McLaren AW, Forrester LM, Glancey MJ, Lang MA, Wolf CR. Identification of the human liver cytochrome P-450 responsible for coumarin 7-hydroxylase activity. Biochem J 1990; 267:365-371.
    • (1990) Biochem J , vol.267 , pp. 365-371
    • Miles, J.S.1    McLaren, A.W.2    Forrester, L.M.3    Glancey, M.J.4    Lang, M.A.5    Wolf, C.R.6
  • 11
    • 7144257874 scopus 로고    scopus 로고
    • A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3, 5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)
    • Nunoya K-I, Yokoi T, Kimura K, Inoue K, Kodama T, Funayama M, et al. A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3, 5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502). Pharmacogenetics 1998; 8:239-249.
    • (1998) Pharmacogenetics , vol.8 , pp. 239-249
    • Nunoya, K.-I.1    Yokoi, T.2    Kimura, K.3    Inoue, K.4    Kodama, T.5    Funayama, M.6
  • 13
    • 0028556582 scopus 로고
    • Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): Mutational specificity in the gpt gene of AS52 cells
    • Tiano HF, Wang R-L, Hosokawa M, Crepsi C, Tindal KR, Langenbach R. Human CYP2A6 activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK): mutational specificity in the gpt gene of AS52 cells. Carcinogenesis 1994; 15:2859-2866.
    • (1994) Carcinogenesis , vol.15 , pp. 2859-2866
    • Tiano, H.F.1    Wang, R.-L.2    Hosokawa, M.3    Crepsi, C.4    Tindal, K.R.5    Langenbach, R.6
  • 14
    • 0025022689 scopus 로고
    • The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in liver microsomes
    • Yamano S, Tatsuno J, Gonzalez FJ. The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in liver microsomes. Biochemistry 1990; 29:1322-1329.
    • (1990) Biochemistry , vol.29 , pp. 1322-1329
    • Yamano, S.1    Tatsuno, J.2    Gonzalez, F.J.3
  • 15
    • 0026744568 scopus 로고
    • Cytochrome P450 2EJ and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
    • Yamazaki H, Inui Y, Yun C-H, Guengerich FP, Shimada T. Cytochrome P450 2EJ and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis 1992; 13:1789-1794.
    • (1992) Carcinogenesis , vol.13 , pp. 1789-1794
    • Yamazaki, H.1    Inui, Y.2    Yun, C.-H.3    Guengerich, F.P.4    Shimada, T.5
  • 16
    • 0031947888 scopus 로고    scopus 로고
    • Genetic polymorphism of drug metabolizing enzymes: New mutations in CYP2D6 and CYP2A6 genes in Japanese
    • Yokoi T, Kamataki T. Genetic polymorphism of drug metabolizing enzymes: new mutations in CYP2D6 and CYP2A6 genes in Japanese. Pharmaceutical Res 1998; 15:517-524.
    • (1998) Pharmaceutical Res , vol.15 , pp. 517-524
    • Yokoi, T.1    Kamataki, T.2
  • 17
    • 0025841777 scopus 로고
    • Purification and characterization of human liver microsomal cytochrome P-450 2A6
    • Yun CH, Shimada T, Guengerich FP. Purification and characterization of human liver microsomal cytochrome P-450 2A6. Mol Pharmacol 1991; 40:679-685.
    • (1991) Mol Pharmacol , vol.40 , pp. 679-685
    • Yun, C.H.1    Shimada, T.2    Guengerich, F.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.