Induction of vascular endothelial growth factor (VEGF) by hyperthermia and/or an angiogenesis inhibitor

International Journal of Hyperthermia

Volumn 15, Issue 4, 1999, Pages 267-278

  Kanamori, S ^a   Nishimura, Y ^b   Okuno, Y ^a   Horii, N ^a   Saga, T ^a   Hiraoka, M ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Anti angiogenic agent; Hyperthermia; Hypoxia; Vascular endothelial growth factor (VEGF)

Indexed keywords

ANGIOGENESIS INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE; VASCULOTROPIN;

ANIMAL EXPERIMENT; ARTICLE; HISTOLOGY; HUMAN; HYPERTHERMIC THERAPY; IMMUNOHISTOCHEMISTRY; INTRATUMORAL DRUG ADMINISTRATION; MALE; MOUSE; PROTEIN EXPRESSION; TUMOR VASCULARIZATION;

ANIMALS; CYCLOHEXANES; ENDOTHELIAL GROWTH FACTORS; HYPERTHERMIA, INDUCED; IMMUNOHISTOCHEMISTRY; LYMPHOKINES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; SESQUITERPENES; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0032803466     PISSN: 02656736     EISSN: None     Source Type: Journal    
DOI: 10.1080/026567399285648     Document Type: Article

References (24)

1. BREM, H., and FOLKMAN, J., 1993, Analysis of experimental antiangiogenic therapy. Journal of Pediatric Surgery, 28, 445-450.
2. BROWN, L. F., BERSE, B., JACKMAN, R. W., TOGNAZZI, K., MANSEAU, E. J., SENGER, D. R., and DVORAK, H. F., 1993, Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Research, 53, 4727-4735.
3. BROWN, S. L., HUNT, J. W., and HILL, R. P., 1992, Differential thermal sensitivity of tumour and normal tissue microvascular response during hyperthermia. International Journal of Hyperthermia, 8, 501-514.
4. FERRARA, N., and DAVIS-SMYTH, T., 1997, The biology of vascular endothelial growth factor. Endocrine Reviews, 18, 4-25.
5. FOLKMAN, J., 1995, Angiogenesis in cancer, vascular, rheumatoid and other disease. Nature Medicine, 1, 27-31.
6. HOLDEN, S. A., and TEICHER, B. A., 1995, Combinations of TNP-470 or SR-4233 with anti-tumour alkylating agents in EMT-6 spheroids and monolayers. International Journal of Oncology, 7, 777-781.
7. INGBER, D., FUJITA, T., KISHIMOTO, S., SUDO, K., KANAMARU, T., BREM, H., and FOLKMAN, J., 1990, Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth. Nature, 348, 555-557.
8. INOUE, K., OZEKI, Y., SUGANUMA, T., SUGIURA, Y., and TANAKA, S., 1997, Vascular endothelial growth factor expression in primary esophageal squamous cell carcinoma. Association with angiogenesis and tumour progression. Cancer, 79, 206-213.
9. KAWARADA, Y., ISHIKURA, H., KISHIMOTO, T., SAITO, K., TAKAHASHI, T., KATO, H., and YOSHIKI, T., 1997, Inhibitory effects of the antiangiogenic agent TNP-470 on establishment and growth of hematogenous metastasis of human pancreatic carcinoma in SCID beige mice in vivo. Pancreas, 15, 251-257.
10. KUSAKA, M., SUDO, K., MATSUTANI, E., KOZAI, Y., MARUI, S., FUJITA, T., INGBER, D., and FOLKMAN, J., 1994, Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470). British Journal of Cancer, 69, 212-216.
11. MINCHENKO, A., SALCEDA, S., BAUER, T., and CARO, J., 1994, Hypoxia regulatory elements of the human vascular endothelial growth factor gene. Cellular and Molecular Biology Research, 40, 35-39.
12. MURATA, R., NISHIMURA, Y., and HIRAOKA, M., 1997, An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma. International Journal of Radiation Oncology, Biology, Physics, 15, 1107-1113.
13. NISHIMURA, Y., HIRAOKA, M., JO, S., AKUTA, K., YUKAWA, Y., SHIBAMOTO, Y., TAKAHASHI, M., and ABE, M., 1988b, Microangiographic and histologic analysis of the effects of hyperthermia on murine tumour vasculature. International Journal of Radiation Oncology, Biology, Physics, 15, 411-420.
14. NISHIMURA, Y., MURATA, R., and HIRAOKA, M., 1996, Combined effects of an angiogenesis inhibitor (TNP-470) and hyperthermia. British Journal of Cancer, 73, 270-274.
15. NISHIMURA, Y., SHIBAMOTO, Y., JO, S., AKUTA, K., HIRAOKA, M., TAKAHASHI, M., and ABE, M., 1988a, Relationship between heat, induced vascular damage and thermosensitivity in four mouse tumors. Cancer Research, 48, 7226-7230.
16. REINHOLD, H. S., and ENDRICH, B., 1986, Tumour microcirculation as a target for hyperthermia. International Journal of Hyperthermia, 2, 111-137.
17. SHIBATA, T., SHIBAMOTO, Y., SASAI, K., OYA, N., MURATA, R., TAKAGI, T., HIRAOKA, M., and ABE, M., 1996, Comparison of in vivo efficacy of hypoxic cytotoxin tirapazamine and hypoxic cell radiosensitizer KU-2285 in combination with single and fractionated irradiation. Japanese Journal of Cancer Research, 87, 98-104.
18. SHWEIKI, D., ITIN, A., SOFFER, D., and KESHET, E., 1992, Vascular endothelial growth factor induced by hypoxia may mediate hypoxia, initiated angiogenesis. Nature, 359, 843-845.
19. SONG, C. W., 1984, Effect of local hyperthermia on blood flow and microenvironment: A review. Cancer Research, 44 (Suppl.), 4721s-4730s.
20. TOI, M., TAKAYANAGI, T., SOUMA, R., and TOMINAGA, T., 1994, Inhibition of vascular endothelial growth factor induced cell growth by an angiogenesis inhibitor AGM-1470 in capillary endothelial cells. Oncology Report, 1, 423-426.
21. VAUPEL, P., KALLINOWSKI, F., and KLUGE, M., 1988, Pathophysiology of tumors in hyperthermia. Recent Results in Cancer Research, 107, 65-75.
22. YAMAOKA, M., YAMAMOTO, T., MASAKI, T., IKEYAMA, S., SUDO, K., and FUJITA, T., 1993, Inhibition of tumour growth and metastasis of rodent tumors by the angiogenesis inhibitor O-(Chloroacetyl-carbamoyl) fumagillol (TNP-470; AGM-1470). Cancer Research, 53, 4262-4267.
23. YANASE, T., MASAKI, T., FUJITA, K., KODAMA, S., and TANAKA, K., 1993, Inhibitory effect of angiogenesis inhibitor TNP-470 on tumour growth and metastasis of human cell lines in vitro and in vivo. Cancer Research, 53, 2566-2570.
24. YANO, T., TANASE, M., WATANABE, A., SAWADA, H., YAMADA, Y., SHINO, Y., NAKANO, H., and OHNISHI, T., 1995, Enhancement effect of an anti-angiogenic agent, TNP-470, on hyperthermia, induced growth suppression of human esophageal and gastric cancers transplantable to nude mice. Anticancer Research, 15, 1355-1358.