-
1
-
-
84966192535
-
The histological structure of some human lung cancers and possible implications for radiotherapy
-
Thomlinson, R. H. and Gray, L. H. The histological structure of some human lung cancers and possible implications for radiotherapy. Br. J. Cancer, 9, 539-549 (1955).
-
(1955)
Br. J. Cancer
, vol.9
, pp. 539-549
-
-
Thomlinson, R.H.1
Gray, L.H.2
-
2
-
-
0021972468
-
Chemical sensitizers for hypoxic cells: A decade of experience in clinical radiotherapy
-
Dische, S. Chemical sensitizers for hypoxic cells: a decade of experience in clinical radiotherapy. Radiother. Oncol., 3, 97-115 (1985).
-
(1985)
Radiother. Oncol.
, vol.3
, pp. 97-115
-
-
Dische, S.1
-
3
-
-
0024331256
-
Sensitization of hypoxic tumour cells - Clinical experience
-
Overgaard, J. Sensitization of hypoxic tumour cells - clinical experience. Int. J. Radiat. Biol., 56, 801-811 (1989).
-
(1989)
Int. J. Radiat. Biol.
, vol.56
, pp. 801-811
-
-
Overgaard, J.1
-
4
-
-
0018760476
-
Evidence for acutely hypoxic cells in mouse tumors and a possible mechanism of reoxygenation
-
Brown, J. M. Evidence for acutely hypoxic cells in mouse tumors and a possible mechanism of reoxygenation. Br. J. Cancer, 52, 650-656 (1979).
-
(1979)
Br. J. Cancer
, vol.52
, pp. 650-656
-
-
Brown, J.M.1
-
5
-
-
0021276479
-
Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data
-
Moulder, J. E. and Rockwell, S. Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data. Int. J. Radiat. Oncol. Biol. Phys., 10, 695-712 (1984).
-
(1984)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.10
, pp. 695-712
-
-
Moulder, J.E.1
Rockwell, S.2
-
6
-
-
0022537042
-
Tumor oxygenation and reoxygenation during radiation therapy: Their importance in predicting tumor response
-
Kallman, R. F. and Dorie, M. J. Tumor oxygenation and reoxygenation during radiation therapy: their importance in predicting tumor response. Int. J. Radiat. Oncol. Biol. Phys., 12, 681-685 (1986).
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 681-685
-
-
Kallman, R.F.1
Dorie, M.J.2
-
7
-
-
0023107539
-
Intermittent blood flow in a murine tumour: Radiobiological effects
-
Chaplin, D. J., Olive, F. L. and Durand, R. E. Intermittent blood flow in a murine tumour: radiobiological effects. Cancer Res., 47, 597-661 (1987).
-
(1987)
Cancer Res.
, vol.47
, pp. 597-661
-
-
Chaplin, D.J.1
Olive, F.L.2
Durand, R.E.3
-
9
-
-
0019507711
-
A marker for hypoxic cells with potential clinical applicability
-
Chapman, J. D., Franko, A. J. and Sharplin, J. A marker for hypoxic cells with potential clinical applicability. Br. J. Cancer, 43, 546-550 (1981).
-
(1981)
Br. J. Cancer
, vol.43
, pp. 546-550
-
-
Chapman, J.D.1
Franko, A.J.2
Sharplin, J.3
-
10
-
-
0026585518
-
123I-iodoazomycin arabinoside: Preliminary report of a clinical study
-
123I-iodoazomycin arabinoside: preliminary report of a clinical study. Br. J. Cancer, 65, 90-95 (1992).
-
(1992)
Br. J. Cancer
, vol.65
, pp. 90-95
-
-
Parliament, M.B.1
Chapman, J.D.2
Urtasun, R.C.3
McEwan, A.J.4
Goldberg, L.5
Mercer, J.R.6
Mannan, R.H.7
Wiebe, L.I.8
-
11
-
-
0025972967
-
A review of hypoxic cell radiosensitization
-
Dische, S. A review of hypoxic cell radiosensitization. Int. J. Radiat. Oncol. Biol. Phys., 20, 147-152 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 147-152
-
-
Dische, S.1
-
12
-
-
0026089349
-
Nimorazole as a hypoxic radiosensitizer in the treatment of supraglottic larynx and pharynx carcinoma. First report from the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85
-
Overgaard, J., Sand Hansen, H., Lindeløv, B., Overgaard, M., Jørgensen, K., Rasmusson, B. and Berthelsen, A. Nimorazole as a hypoxic radiosensitizer in the treatment of supraglottic larynx and pharynx carcinoma. First report from the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85. Radiother. Oncol., 20 (Suppl.), 143-149 (1991).
-
(1991)
Radiother. Oncol.
, vol.20
, Issue.SUPPL.
, pp. 143-149
-
-
Overgaard, J.1
Sand Hansen, H.2
Lindeløv, B.3
Overgaard, M.4
Jørgensen, K.5
Rasmusson, B.6
Berthelsen, A.7
-
13
-
-
0022486242
-
Studies of the in vivo and in vitro cytotoxicity of the drug RSU-1069
-
Hill, R. P., Gulyas, S. and Whitmore, G. F. Studies of the in vivo and in vitro cytotoxicity of the drug RSU-1069. Br. J. Cancer, 53, 743-751 (1986).
-
(1986)
Br. J. Cancer
, vol.53
, pp. 743-751
-
-
Hill, R.P.1
Gulyas, S.2
Whitmore, G.F.3
-
14
-
-
0024363529
-
Characteristics of fluorinated nitroazoles as hypoxic cell radiosensitizers
-
Shibamoto, Y., Nishimoto, S., Shimokawa, K., Hisanaga, Y., Zhou, L., Wang, J., Sasai, K., Takahashi, M., Abe, M. and Kagiya, T. Characteristics of fluorinated nitroazoles as hypoxic cell radiosensitizers. Int. J. Radiat. Oncol. Biol. Phys., 16, 1045-1048 (1989).
-
(1989)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.16
, pp. 1045-1048
-
-
Shibamoto, Y.1
Nishimoto, S.2
Shimokawa, K.3
Hisanaga, Y.4
Zhou, L.5
Wang, J.6
Sasai, K.7
Takahashi, M.8
Abe, M.9
Kagiya, T.10
-
15
-
-
0025895726
-
A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer
-
Sasai, K., Nishimoto, S., Shimokawa, K., Hisanaga, Y., Kitakabu, Y., Shibamoto, Y., Zhou, L., Wang, J., Takahashi, M., Kagiya, T. and Abe, M. A fluorinated 2-nitroimidazole, KU-2285, as a new hypoxic cell radiosensitizer. Int. J. Radiat. Oncol. Biol. Phys., 20, 1249-1254 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 1249-1254
-
-
Sasai, K.1
Nishimoto, S.2
Shimokawa, K.3
Hisanaga, Y.4
Kitakabu, Y.5
Shibamoto, Y.6
Zhou, L.7
Wang, J.8
Takahashi, M.9
Kagiya, T.10
Abe, M.11
-
16
-
-
0026589976
-
Radiosensitization efficacy of KU-2285, RP-170, and etanidazole at low radiation doses: Assessment by in vitro cytokinesis-block micronucleus assay
-
Shibamoto, Y., Streffer, C., Sasai, K., Oya, N. and Abe, M. Radiosensitization efficacy of KU-2285, RP-170, and etanidazole at low radiation doses: assessment by in vitro cytokinesis-block micronucleus assay. Int. J. Radiat. Biol., 61, 473-478 (1992).
-
(1992)
Int. J. Radiat. Biol.
, vol.61
, pp. 473-478
-
-
Shibamoto, Y.1
Streffer, C.2
Sasai, K.3
Oya, N.4
Abe, M.5
-
17
-
-
0028246226
-
Comparison of radiosensitizing effect of KU-2285 and SR-2508 at low drug concentrations and doses
-
Shibata, T., Shibamoto, Y., Oya, N., Sasai, K., Murata, R., Ishigaki, T. and Abe, M. Comparison of radiosensitizing effect of KU-2285 and SR-2508 at low drug concentrations and doses. Int. J. Radiat. Oncol. Biol. Phys., 29, 587-590 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 587-590
-
-
Shibata, T.1
Shibamoto, Y.2
Oya, N.3
Sasai, K.4
Murata, R.5
Ishigaki, T.6
Abe, M.7
-
18
-
-
0022493495
-
SR-4233: A new bioreductive agent with high selective toxicity for hypoxic mammalian cells
-
Zeman, E. M., Brown, J. M., Lemmon, M. J., Hirst, V. K. and Lee, W. W. SR-4233: a new bioreductive agent with high selective toxicity for hypoxic mammalian cells. Int. J. Radiat. Oncol. Biol. Phys., 12, 1239-1242 (1986).
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1239-1242
-
-
Zeman, E.M.1
Brown, J.M.2
Lemmon, M.J.3
Hirst, V.K.4
Lee, W.W.5
-
19
-
-
0023689603
-
Metabolism of SR 4233 by Chinese hamster ovary cells: The basis of selective hypoxic cytotoxicity
-
Baker, M. A., Zeman, E. M., Hirst, V. K. and Brown, J. M. Metabolism of SR 4233 by Chinese hamster ovary cells: the basis of selective hypoxic cytotoxicity. Cancer Res., 48, 5947-5952 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 5947-5952
-
-
Baker, M.A.1
Zeman, E.M.2
Hirst, V.K.3
Brown, J.M.4
-
20
-
-
0023750547
-
Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR 4233
-
Zeman, E. M., Hirst, V. K., Lemmon, M. J. and Brown, J. M. Enhancement of radiation-induced tumor cell killing by the hypoxic cell toxin SR 4233. Radiother. Oncol., 12, 209-218 (1988).
-
(1988)
Radiother. Oncol.
, vol.12
, pp. 209-218
-
-
Zeman, E.M.1
Hirst, V.K.2
Lemmon, M.J.3
Brown, J.M.4
-
21
-
-
0025646401
-
Potentiation by the hypoxic cytotoxin SR 4233 of cell killing produced by fractionated irradiation of mouse tumors
-
Brown, J. M. and Lemmon, M. J. Potentiation by the hypoxic cytotoxin SR 4233 of cell killing produced by fractionated irradiation of mouse tumors. Cancer Res., 50, 7745-7749 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 7745-7749
-
-
Brown, J.M.1
Lemmon, M.J.2
-
22
-
-
0026083865
-
Aerobic radiosensitization by SR 4233 in rodent and human cells: Mechanistic and therapeutic implications
-
Zeman, E. M. and Brown, J. M. Aerobic radiosensitization by SR 4233 in rodent and human cells: mechanistic and therapeutic implications. Int. J. Radiat. Biol., 59, 117-131 (1991).
-
(1991)
Int. J. Radiat. Biol.
, vol.59
, pp. 117-131
-
-
Zeman, E.M.1
Brown, J.M.2
-
23
-
-
0027288316
-
SR 4233 (tirapazamine): A new anticancer drug exploiting hypoxia in solid tumours
-
Brown, J. M. SR 4233 (tirapazamine): a new anticancer drug exploiting hypoxia in solid tumours. Br. J. Cancer, 67, 1163-1170 (1993).
-
(1993)
Br. J. Cancer
, vol.67
, pp. 1163-1170
-
-
Brown, J.M.1
-
24
-
-
0028339820
-
Bioreductive drugs for cancer therapy: The search for tumor specificity
-
Adams, G. E. and Stratford, I. J. Bioreductive drugs for cancer therapy: the search for tumor specificity. Int. J. Radiat. Oncol. Biol. Phys., 29, 231-238 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 231-238
-
-
Adams, G.E.1
Stratford, I.J.2
-
25
-
-
0028084787
-
Tumour hypoxia: The picture has changed in the 1990s
-
Brown, J. M. and Giaccia, A. J. Tumour hypoxia: the picture has changed in the 1990s. Int. J. Radiat. Biol., 65, 95-102 (1994).
-
(1994)
Int. J. Radiat. Biol.
, vol.65
, pp. 95-102
-
-
Brown, J.M.1
Giaccia, A.J.2
-
26
-
-
0026572272
-
Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive antitumor agents: Pharmacology and activity in vitro and in vivo
-
Minchinton, A. I., Lemmon, M. J., Tracy, M., Pollart, D. J., Martinez, A. P., Tosto, L. M. and Brown, J. M. Second-generation 1,2,4-benzotriazine 1,4-di-N-oxide bioreductive antitumor agents: pharmacology and activity in vitro and in vivo. Int. J. Radiat. Oncol. Biol. Phys., 22, 701-705 (1992).
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.22
, pp. 701-705
-
-
Minchinton, A.I.1
Lemmon, M.J.2
Tracy, M.3
Pollart, D.J.4
Martinez, A.P.5
Tosto, L.M.6
Brown, J.M.7
-
27
-
-
0028200683
-
Muscle cramping in Phase I clinical trials of tirapazamine (SR 4233) with and without radiation
-
Doherty, N., Hancock, S. L., Kaye, S., Coleman, C. N., Shulman, L., Marquez, C., Mariscal, C., Rampling, R., Senan, S. and Roemeling, R. V. Muscle cramping in Phase I clinical trials of tirapazamine (SR 4233) with and without radiation. Int. J. Radiat. Oncol. Biol. Phys., 29, 379-382 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 379-382
-
-
Doherty, N.1
Hancock, S.L.2
Kaye, S.3
Coleman, C.N.4
Shulman, L.5
Marquez, C.6
Mariscal, C.7
Rampling, R.8
Senan, S.9
Roemeling, R.V.10
-
28
-
-
0026056373
-
In vivo radiosensitizing activity of a new fluorinated hypoxic cell radiosensitizer, KU-2285, in combination with radiation dose fractionation
-
Sasai, K., Fushiki, M., Yukawa, Y., Suyama, S., Iwai, H., Shibamoto, Y., Nishimoto, S., Takahashi, M. and Abe, M. In vivo radiosensitizing activity of a new fluorinated hypoxic cell radiosensitizer, KU-2285, in combination with radiation dose fractionation. Int. J. Radiat. Oncol. Biol. Phys., 21, 1231-1234 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.21
, pp. 1231-1234
-
-
Sasai, K.1
Fushiki, M.2
Yukawa, Y.3
Suyama, S.4
Iwai, H.5
Shibamoto, Y.6
Nishimoto, S.7
Takahashi, M.8
Abe, M.9
-
29
-
-
0027370858
-
In vivo radiosensitization efficacy of KU-2285 and etanidazole at clinically relevant low radiation doses
-
Oya, N., Shibamoto, Y., Sasai, K., Sugiyama, T. and Abe, M. In vivo radiosensitization efficacy of KU-2285 and etanidazole at clinically relevant low radiation doses. Int. J. Radiat. Oncol. Biol. Phys., 27, 1113-1119 (1993).
-
(1993)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.27
, pp. 1113-1119
-
-
Oya, N.1
Shibamoto, Y.2
Sasai, K.3
Sugiyama, T.4
Abe, M.5
-
30
-
-
0026778985
-
Phannacokinetics of fluorinated 2-nitroimidazole hypoxic cell radiosensitizers in murine peripheral nervous tissue
-
Sasai, K., Iwai, H., Yoshizawa, T., Nishimoto, S., Shibamoto, Y., Kitakabu, Y., Oya, N., Takahashi, M. and Abe, M. Phannacokinetics of fluorinated 2-nitroimidazole hypoxic cell radiosensitizers in murine peripheral nervous tissue. Int. J. Radiat. Biol., 62, 221-227 (1992).
-
(1992)
Int. J. Radiat. Biol.
, vol.62
, pp. 221-227
-
-
Sasai, K.1
Iwai, H.2
Yoshizawa, T.3
Nishimoto, S.4
Shibamoto, Y.5
Kitakabu, Y.6
Oya, N.7
Takahashi, M.8
Abe, M.9
-
31
-
-
0022478693
-
Variation in the hypoxic fraction among mouse tumors of different types, sizes, and sites
-
Shibamoto, Y., Yukawa, Y., Tsutsui, K., Takahashi, M. and Abe, M. Variation in the hypoxic fraction among mouse tumors of different types, sizes, and sites. Jpn. J. Cancer Res., 77, 908-915 (1986).
-
(1986)
Jpn. J. Cancer Res.
, vol.77
, pp. 908-915
-
-
Shibamoto, Y.1
Yukawa, Y.2
Tsutsui, K.3
Takahashi, M.4
Abe, M.5
-
32
-
-
0025806366
-
Variations of the hypoxic fraction in the SCCVII tumors after single dose and during fractionated radiation therapy: Assessment without anesthesia or physical restraint of mice
-
Kitakabu, Y., Shibamoto, Y., Sasai, K., Ono, K. and Abe, M. Variations of the hypoxic fraction in the SCCVII tumors after single dose and during fractionated radiation therapy: assessment without anesthesia or physical restraint of mice. Int. J. Radiat. Oncol. Biol. Phys., 20, 709-714 (1991).
-
(1991)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.20
, pp. 709-714
-
-
Kitakabu, Y.1
Shibamoto, Y.2
Sasai, K.3
Ono, K.4
Abe, M.5
-
33
-
-
0023057193
-
Reoxygenation after a single dose of 15 Gy in the EMT6/KU sarcoma
-
Shibamoto, Y., Nishimura, Y., Nishidai, T., Takahashi, M. and Abe, M. Reoxygenation after a single dose of 15 Gy in the EMT6/KU sarcoma. Nippon Acta Radiol., 46, 1319-1323 (1986).
-
(1986)
Nippon Acta Radiol.
, vol.46
, pp. 1319-1323
-
-
Shibamoto, Y.1
Nishimura, Y.2
Nishidai, T.3
Takahashi, M.4
Abe, M.5
-
34
-
-
0023292750
-
The radiation response of SCCVII tumor cells in C3H/He mice varies with the irradiation conditions
-
Shibamoto, Y., Sasai, K. and Abe, M. The radiation response of SCCVII tumor cells in C3H/He mice varies with the irradiation conditions. Radiat. Res., 109, 352-354 (1987).
-
(1987)
Radiat. Res.
, vol.109
, pp. 352-354
-
-
Shibamoto, Y.1
Sasai, K.2
Abe, M.3
-
35
-
-
0026559474
-
Evaluation of bioreductive drugs in multicell spheroids
-
Durand, R. E. and Olive, P. L. Evaluation of bioreductive drugs in multicell spheroids. Int. J. Radiat. Oncol. Biol. Phys., 22, 689-692 (1992).
-
(1992)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.22
, pp. 689-692
-
-
Durand, R.E.1
Olive, P.L.2
-
36
-
-
0025968030
-
SR4233: A tumor specific radiosensitizer active in fractionated radiation regimes
-
Brown, J. M. and Lemmon, M. J. SR4233: a tumor specific radiosensitizer active in fractionated radiation regimes. Radiother. Oncol., 20 (Suppl.), 151-156 (1991).
-
(1991)
Radiother. Oncol.
, vol.20
, Issue.SUPPL.
, pp. 151-156
-
-
Brown, J.M.1
Lemmon, M.J.2
-
37
-
-
0025020275
-
Aerobic radiosensitization by SR4233 in vitro and in vivo
-
Zeman, E. M., Lemmon, M. J. and Brown, J. M. Aerobic radiosensitization by SR4233 in vitro and in vivo. Int. J. Radiat. Oncol. Biol. Phys., 18, 125-132 (1990).
-
(1990)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.18
, pp. 125-132
-
-
Zeman, E.M.1
Lemmon, M.J.2
Brown, J.M.3
-
39
-
-
0021749137
-
Intraoperative radiotherapy - Past, present, and future
-
Abe, M. Intraoperative radiotherapy - past, present, and future. Int. J. Radiat. Oncol. Biol. Phys., 10, 1987-1990 (1984).
-
(1984)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.10
, pp. 1987-1990
-
-
Abe, M.1
-
40
-
-
0022471797
-
Sensitizers and radiation dose fractionation: Results and interpretations
-
Hill, R. P. Sensitizers and radiation dose fractionation: results and interpretations. Int. J. Radiat. Oncol. Biol. Phys., 12, 1049-1054 (1986).
-
(1986)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.12
, pp. 1049-1054
-
-
Hill, R.P.1
-
41
-
-
0028246224
-
Reoxygenation in the SCCVII tumor after KU-2285 sensitization plus single or fractionated irradiation
-
Shibamoto, Y., Kitakabu, Y., Murata, R., Oya, N., Shibata, T., Sasai, K., Takahashi, M. and Abe, M. Reoxygenation in the SCCVII tumor after KU-2285 sensitization plus single or fractionated irradiation. Int. J. Radiat. Oncol. Biol. Phys., 29, 583-586 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 583-586
-
-
Shibamoto, Y.1
Kitakabu, Y.2
Murata, R.3
Oya, N.4
Shibata, T.5
Sasai, K.6
Takahashi, M.7
Abe, M.8
-
42
-
-
0028235953
-
Reoxygenation and rehypoxiation in the SCCVII mouse tumor
-
Kim, I. H. and Brown, J. M. Reoxygenation and rehypoxiation in the SCCVII mouse tumor. Int. J. Radiat. Oncol. Biol. Phys., 29, 493-497 (1994).
-
(1994)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.29
, pp. 493-497
-
-
Kim, I.H.1
Brown, J.M.2
-
43
-
-
0024335180
-
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid
-
Zwi, L. J., Baguley, B. C., Gavin, J. B. and Wilson, W. R. Blood flow failure as a major determinant in the antitumor action of flavone acetic acid. J. Natl. Cancer Inst., 81, 1005-1013 (1989).
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 1005-1013
-
-
Zwi, L.J.1
Baguley, B.C.2
Gavin, J.B.3
Wilson, W.R.4
|