Interferon-gamma (IFN-γ) regulates production of IL-10 and IL-12 in human herpesvirus-6 (HHV-6)-infected monocyte/macrophage lineage

Clinical and Experimental Immunology

Volumn 109, Issue 3, 1997, Pages 421-425

  Li, C ^a   Goodrich, J M ^b   Yang, X ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Human herpesvires 6; IL 10; IL 12; Interferon gamma

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12;

ARTICLE; CELLULAR IMMUNITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HERPES; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; IMMUNE RESPONSE; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0030881353     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.4661362.x     Document Type: Article

References (16)

1. Pellett PE, Black JB, Yamamoto M. Human herpesvirus 6: the virus and the search for its role as a human pathogen. Adv Virus Res 1992; 41:1-51.
2. Pruksananonda P, Hall CB, Insel RA et al. Primary human herpesvirus 6 infection in young children. N Eng J Med 1942; 326:1445-50.
3. Knox KK, Garrigan DR. Disseminated active HHV-6 infection in patients with AIDS. Lancet 1994; 343:577-8.
4. Kondo K, Kondo T, Okuno T et al. Latent human herpesvirus 6 infection of human monocytes/macrophages. J Gen Virol 1991; 72: 1401-8.
5. Brunda MJ. Interleukin-12. J Leuk Biol 1994; 55:280-94.
6. Mosmann TR. Properties and functions of interleukin-10. Adv Immunol 1994; 56:1-27.
7. Balachandran N, Amelse RE, Zhou WW et al. Identification of proteins specific for human herpesvirus 6-infected human T cells. J Virol 1989; 63:2835-40.
8. Mattei S, Colombo MP, Melani C et al. Expression of cytokine/growth factors and their receptors in human melanoma and melanocytes. Int J Cancer 1994; 56:853-7.
9. Fan JA, Bass HZ, Fahey JL. Elevated IFN-γ and decreased IL-2 gene expression are associated with HIV infection. J Immunol 1993; 151: 5031-40.
10. D'Andrea A, Aste-Amezaga M, Valiante NM et al. Interleukin 10 (IL-10) inhibits human lymphocyte interferon-γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med 1993;178:1041-8.
11. Akridge RE, Oyafuso LKM, Reed SG. IL-10 is induced during HIV infection and is capable of decreasing viral replication in human macrophages. J Immunol 1994; 153:5782-9.
12. Tsutsumi H, Matsuda K, Sone S et al. Respiratory syncytial virus-induced cytokine production by neonatal macrophages. Clin Exp Immunol 1996; 106:442-6.
13. Chomarat P, Rissoan MC, Banchereau J et al. Interferon γ inhibits interleukin 10 production by monocytes. J Exp Med 1993; 177:523-7.
14. Cassatella MA, Meda L, Gasperini S et al. Interleukin-12 production by human polymorphonuclear leukocytes. Eur J Immunol 1995; 25: 1-5.
15. Hayes MP, Wang JH, Norcross MA. Regulation of interleukin-12 expression in human monocytes: selective priming by interferon-γ of lipopolysaccharide-inducible P35 and P40 genes. Blood 1995; 86:646-50.
16. Romagnan S. Biology of human Th1 and Th2 cells. J Clin Immunol 1995; 15:121-92.