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Volumn 80, Issue SUPPL. 1, 1999, Pages 28-33

Target genes and target cells in carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOGEN; GROWTH FACTOR; PROTEIN P16; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 0032796982     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (8)

References (58)
  • 1
    • 0024334362 scopus 로고
    • Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions
    • Aldaz CM, Trono T, Larcher F, Slaga TJ and Conti CJ (1980) Sequential trisomization of chromosomes 6 and 7 in mouse skin premalignant lesions. Mol Carcinogen 2: 22-26
    • (1980) Mol Carcinogen , vol.2 , pp. 22-26
    • Aldaz, C.M.1    Trono, T.2    Larcher, F.3    Slaga, T.J.4    Conti, C.J.5
  • 2
    • 0025041030 scopus 로고
    • Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter
    • Bailleul B, Surani MA, While S, Barton SC, Brown K, Blessing M, Jorcano J and Balmain A (1990) Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. Cell 62: 697-708
    • (1990) Cell , vol.62 , pp. 697-708
    • Bailleul, B.1    Surani, M.A.2    While, S.3    Barton, S.C.4    Brown, K.5    Blessing, M.6    Jorcano, J.7    Balmain, A.8
  • 4
    • 0020586334 scopus 로고
    • Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene
    • Balmain A, and Pragnell IB (1983) Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene. Nature 303: 72-74
    • (1983) Nature , vol.303 , pp. 72-74
    • Balmain, A.1    Pragnell, I.B.2
  • 5
    • 0021141757 scopus 로고
    • Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas
    • Balmain A, Ramsden M, Bowden GT and Smith J (1984) Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature 307: 658-660
    • (1984) Nature , vol.307 , pp. 658-660
    • Balmain, A.1    Ramsden, M.2    Bowden, G.T.3    Smith, J.4
  • 6
    • 84966175904 scopus 로고
    • A new, quantitative approach to the study of the stages of chemical carcinogenesis in the mouse's skin
    • Berenblum I and Shubik P (1947) A new, quantitative approach to the study of the stages of chemical carcinogenesis in the mouse's skin. Br J Cancer 1: 383-386
    • (1947) Br J Cancer , vol.1 , pp. 383-386
    • Berenblum, I.1    Shubik, P.2
  • 10
    • 0013953906 scopus 로고
    • Quantitative aspects of the reaction of some carcinogens with nucleic acids and the possible significance of such reactions in the process of carcinogenesis
    • Brookes P (1966) Quantitative aspects of the reaction of some carcinogens with nucleic acids and the possible significance of such reactions in the process of carcinogenesis. Cancer Res 26: 1994-2003
    • (1966) Cancer Res , vol.26 , pp. 1994-2003
    • Brookes, P.1
  • 11
    • 0022458856 scopus 로고
    • v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis
    • Brown K, Quintanilla M, Ramsden M, Kerr IB, Young S and Balmain A (1986) v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis. Cell 46: 447-456
    • (1986) Cell , vol.46 , pp. 447-456
    • Brown, K.1    Quintanilla, M.2    Ramsden, M.3    Kerr, I.B.4    Young, S.5    Balmain, A.6
  • 12
    • 0025038030 scopus 로고
    • Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumour progression
    • Brown K, Buchmann A and Balmain A (1990) Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumour progression. Proc Nat Acad Sci USA 87: 538-542
    • (1990) Proc Nat Acad Sci USA , vol.87 , pp. 538-542
    • Brown, K.1    Buchmann, A.2    Balmain, A.3
  • 13
    • 0032559976 scopus 로고    scopus 로고
    • The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted
    • Brown K, Strathdee D, Bryson S, Lambic W and Balmain A (1998) The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted. Curr Biol 8: 516-524
    • (1998) Curr Biol , vol.8 , pp. 516-524
    • Brown, K.1    Strathdee, D.2    Bryson, S.3    Lambic, W.4    Balmain, A.5
  • 14
    • 0026385870 scopus 로고
    • Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7
    • Buchmann A, Ruggeri A, Klein Szanto AJP and Balmain A (1991) Progression of squamous carcinoma cells to spindle carcinomas of mouse skin is associated with an imbalance of H-ras alleles on chromosome 7. Cancer Res 51: 4097-4101
    • (1991) Cancer Res , vol.51 , pp. 4097-4101
    • Buchmann, A.1    Ruggeri, A.2    Klein Szanto, A.J.P.3    Balmain, A.4
  • 15
    • 0026349058 scopus 로고
    • Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice
    • Burns PA, Kemp CJ, Gannon JV, Lane DP, Bremner R and Balmain A (1991) Loss of heterozygosity and mutational alterations of the p53 gene in skin tumours of interspecific hybrid mice. Oncogene 6: 2363-2369
    • (1991) Oncogene , vol.6 , pp. 2363-2369
    • Burns, P.A.1    Kemp, C.J.2    Gannon, J.V.3    Lane, D.P.4    Bremner, R.5    Balmain, A.6
  • 16
    • 0018893416 scopus 로고
    • Transforming activity of DNA of chemically transformed and normal cells
    • Cooper GM, Okenquist S and Silverman L (1980) Transforming activity of DNA of chemically transformed and normal cells. Nature 284: 418-421
    • (1980) Nature , vol.284 , pp. 418-421
    • Cooper, G.M.1    Okenquist, S.2    Silverman, L.3
  • 17
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarclis G, Sun TT, Lavker RM (1990)) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis, Cell 61: 1329-1337
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarclis, G.1    Sun, T.T.2    Lavker, R.M.3
  • 18
    • 0030598681 scopus 로고    scopus 로고
    • TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
    • Cui W, Fowlis DJ, Bryson S, Duffic E, Ireland H, Balmain A and Akhurst RJ (1996) TGFβ1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 86: 531-542
    • (1996) Cell , vol.86 , pp. 531-542
    • Cui, W.1    Fowlis, D.J.2    Bryson, S.3    Duffic, E.4    Ireland, H.5    Balmain, A.6    Akhurst, R.J.7
  • 19
    • 0026602416 scopus 로고
    • Expression of simple epithelial keratins in mouse epidermal keratmocytes harbouring Harvey-ras gene alterations
    • Diaz Guerra M, Haddow S, Bauluz C, Jorcano JL, Cano A, Balmain A and Quintanilla M (1992) Expression of simple epithelial keratins in mouse epidermal keratmocytes harbouring Harvey-ras gene alterations, Cancer Res 52: 680-687
    • (1992) Cancer Res , vol.52 , pp. 680-687
    • Diaz Guerra, M.1    Haddow, S.2    Bauluz, C.3    Jorcano, J.L.4    Cano, A.5    Balmain, A.6    Quintanilla, M.7
  • 21
    • 0029782220 scopus 로고    scopus 로고
    • Paradoxical tumour inhibitory effect of p53 loss in transgenic mice expressing epidermal targeted v-rasH, v-fos, or human transforming growth factor alpha
    • Greenhalgh DA, Wang XJ, Donehower LA and Balmain A (1996) Paradoxical tumour inhibitory effect of p53 loss in transgenic mice expressing epidermal targeted v-rasH, v-fos, or human transforming growth factor alpha. Cancer Rev 56: 4413-4423
    • (1996) Cancer Rev , vol.56 , pp. 4413-4423
    • Greenhalgh, D.A.1    Wang, X.J.2    Donehower, L.A.3    Balmain, A.4
  • 24
    • 0027203921 scopus 로고
    • Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumours
    • Kemp CJ, Donehower LA, Bradley A and Balmain A (1993a) Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumours. Cell 74: 813-822
    • (1993) Cell , vol.74 , pp. 813-822
    • Kemp, C.J.1    Donehower, L.A.2    Bradley, A.3    Balmain, A.4
  • 25
    • 0027145128 scopus 로고
    • Allelotype analysis of mouse skin tumours using polymorphic microsatellites: Sequential genetic alterations on chromosomes 6, 7 and 11
    • Kemp CJ, Fee F and Balmain A (1993b) Allelotype analysis of mouse skin tumours using polymorphic microsatellites: sequential genetic alterations on chromosomes 6, 7 and 11. Cancer Research 53: 6022-6027
    • (1993) Cancer Research , vol.53 , pp. 6022-6027
    • Kemp, C.J.1    Fee, F.2    Balmain, A.3
  • 28
    • 0024469982 scopus 로고
    • Multistage chemical carcinogencsis protocols produce spindle cell carcinomas of the mouse skin
    • Klein-Szanto AJP, Larcher F, Bonfil RD and Conti CJ (1989) Multistage chemical carcinogencsis protocols produce spindle cell carcinomas of the mouse skin, Carcinogenesis 10: 2169-2172
    • (1989) Carcinogenesis , vol.10 , pp. 2169-2172
    • Klein-Szanto, A.J.P.1    Larcher, F.2    Bonfil, R.D.3    Conti, C.J.4
  • 29
    • 0031911356 scopus 로고    scopus 로고
    • SMADs; mediators and regulators of TGF-beta signalling
    • Kretzschmar M, Massague J (1998) SMADs; mediators and regulators of TGF-beta signalling. Curr Opin Genet Dev 8: 103-111
    • (1998) Curr Opin Genet Dev , vol.8 , pp. 103-111
    • Kretzschmar, M.1    Massague, J.2
  • 30
    • 0025970229 scopus 로고
    • D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to bcl-1
    • Lammic GA, Fantl V, Smith R, Schuuring E, Brookes S, Michalides R, Dickson C, Arnold A and Peters G (1991) D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to bcl-1. Oncogene 6: 439-444
    • (1991) Oncogene , vol.6 , pp. 439-444
    • Lammic, G.A.1    Fantl, V.2    Smith, R.3    Schuuring, E.4    Brookes, S.5    Michalides, R.6    Dickson, C.7    Arnold, A.8    Peters, G.9
  • 31
    • 0029814061 scopus 로고    scopus 로고
    • Anti-apoptotic activity of low levels of wild-type p53
    • Lassus P, Ferlin M,Pietle J and Hibner U (1996) Anti-apoptotic activity of low levels of wild-type p53. EMBO J 15: 4566-4573
    • (1996) EMBO J , vol.15 , pp. 4566-4573
    • Lassus, P.1    Ferlin, M.2    Pietle, J.3    Hibner, U.4
  • 33
    • 0028051642 scopus 로고
    • Loss of heterozygosity of chromosome 9p21 is associated with the immorial phenotype of neoplastic human head and neck keratinocytes
    • Loughran O, Edington KG, Berry IJ, Clark LJ and Parkinson EK (1994) Loss of heterozygosity of chromosome 9p21 is associated with the immorial phenotype of neoplastic human head and neck keratinocytes. Cancer Res 54: 5045-5049
    • (1994) Cancer Res , vol.54 , pp. 5045-5049
    • Loughran, O.1    Edington, K.G.2    Berry, I.J.3    Clark, L.J.4    Parkinson, E.K.5
  • 35
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signalling: Transient versus sustained extracellular signal regulated kinase activation
    • Marshall CJ (1995) Specificity of receptor tyrosine kinase signalling: transient versus sustained extracellular signal regulated kinase activation. Cell 80: 179-185
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 37
    • 0031955368 scopus 로고    scopus 로고
    • Cancer resistance genes in mice: Models for the study of tumour modifiers
    • Nagase H and Balmain A (1998) Cancer resistance genes in mice: models for the study of tumour modifiers, Trends Genet 14: 139-144
    • (1998) Trends Genet , vol.14 , pp. 139-144
    • Nagase, H.1    Balmain, A.2
  • 38
    • 0029086835 scopus 로고
    • Cancer predisposition in mice: Distinct loci control development of benign and malignant skin tumours
    • Nagase H, Bryson S, Cordell H, Kemp CJ, Fee F and Balmain A (1995) Cancer predisposition in mice: distinct loci control development of benign and malignant skin tumours, Nat Genet 10; 424-429
    • (1995) Nat Genet , vol.10 , pp. 424-429
    • Nagase, H.1    Bryson, S.2    Cordell, H.3    Kemp, C.J.4    Fee, F.5    Balmain, A.6
  • 40
    • 0029836835 scopus 로고    scopus 로고
    • Signature p53 mutation at DNA cross-linking sites in 8-methoxypsorale and ultraviolet A (PUVA)-induced murine skin cancers
    • Nataraj AJ, Black HS and Ananthaswanny HN (1996) Signature p53 mutation at DNA cross-linking sites in 8-methoxypsorale and ultraviolet A (PUVA)-induced murine skin cancers. Proc Natl Acad Sci USA 93: 7961-7965
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7961-7965
    • Nataraj, A.J.1    Black, H.S.2    Ananthaswanny, H.N.3
  • 41
    • 0029662049 scopus 로고    scopus 로고
    • TGFβ1 and Ha-ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumour cells
    • Oft M, Peli J, Rudaz C, Schwarz H, Beug H and Reichmann F. (1996) TGFβ1 and Ha-ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumour cells. Genes Dev 10: 2462-2477
    • (1996) Genes Dev , vol.10 , pp. 2462-2477
    • Oft, M.1    Peli, J.2    Rudaz, C.3    Schwarz, H.4    Beug, H.5    Reichmann, F.6
  • 42
    • 0026720447 scopus 로고
    • Selective mutation of codons 204 and 213 of the p53 gene in rat tumours induced by alkylating N-nitroso compounds
    • Ohgaki H, Hard GC, Hirota N, Mackawa A, Takahashi M and Kleihues p (1992) Selective mutation of codons 204 and 213 of the p53 gene in rat tumours induced by alkylating N-nitroso compounds. Cancer Res 52: 2995-2998
    • (1992) Cancer Res , vol.52 , pp. 2995-2998
    • Ohgaki, H.1    Hard, G.C.2    Hirota, N.3    Mackawa, A.4    Takahashi, M.5    Kleihues, P.6
  • 43
    • 0025281090 scopus 로고
    • Inherited predisposition to cancer
    • Ponder BA (1990) Inherited predisposition to cancer. Trends Genet 6: 213-218
    • (1990) Trends Genet , vol.6 , pp. 213-218
    • Ponder, B.A.1
  • 44
    • 0031817391 scopus 로고    scopus 로고
    • Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo; implications for tumour invasion
    • Portella G, Cumming SA, Liddell J, Chi W, Ireland H, Akhurst RJ and Balmain A (1998) Transforming growth factor beta is essential for spindle cell conversion of mouse skin carcinoma in vivo; implications for tumour invasion. Cell Growth Differ 9: 393-404
    • (1998) Cell Growth Differ , vol.9 , pp. 393-404
    • Portella, G.1    Cumming, S.A.2    Liddell, J.3    Chi, W.4    Ireland, H.5    Akhurst, R.J.6    Balmain, A.7
  • 45
    • 84989405753 scopus 로고
    • The epidermal proliferative unit: The possible role of the central basal cell
    • Potten CS (1974) The epidermal proliferative unit: the possible role of the central basal cell. Cell Tissue Kinel 7: 77-88
    • (1974) Cell Tissue Kinel , vol.7 , pp. 77-88
    • Potten, C.S.1
  • 46
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Ouintanilla M, Brown K, Ramsden M and Balmain A (1986) Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis, Nature 322: 78-80
    • (1986) Nature , vol.322 , pp. 78-80
    • Ouintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 47
  • 49
    • 0027500049 scopus 로고
    • Benzo[a]pyrene-induced murine skin tumours exhibit frequent and characteristic G to T mutations in the p53 gene
    • Ruggeri B, DiRado M, Zhang SY, Bauer B, Goodrow T and Klein-Szanto AJ (1993) Benzo[a]pyrene-induced murine skin tumours exhibit frequent and characteristic G to T mutations in the p53 gene. Proc Natl Acad Sci USA 90: 1013-1017
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1013-1017
    • Ruggeri, B.1    DiRado, M.2    Zhang, S.Y.3    Bauer, B.4    Goodrow, T.5    Klein-Szanto, A.J.6
  • 51
    • 0346381089 scopus 로고
    • Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin
    • Shin C, Shilo B. Goldfarb MP, Dannenberg A and Weinberg RA (1979) Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin. Proc Natl Acad Sci USA 76: 5714-5718
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 5714-5718
    • Shin, C.1    Shilo, B.2    Goldfarb, M.P.3    Dannenberg, A.4    Weinberg, R.A.5
  • 52
    • 0028086502 scopus 로고
    • Developmental decisions in Aspergillus nidulans are modulated by ras activity
    • Som T and Kolaparthi VSR (1994) Developmental decisions in Aspergillus nidulans are modulated by ras activity, Mol Cell Biol 14: 5333-5348
    • (1994) Mol Cell Biol , vol.14 , pp. 5333-5348
    • Som, T.1    Kolaparthi, V.S.R.2
  • 53
    • 0016615917 scopus 로고
    • The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis in mouse skin
    • Van Duuren BL, Sivak A, Katz C, Seidman I and Melchionine S (1975) The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis in mouse skin. Cancer Res 35: 502-505
    • (1975) Cancer Res , vol.35 , pp. 502-505
    • Van Duuren, B.L.1    Sivak, A.2    Katz, C.3    Seidman, I.4    Melchionine, S.5
  • 54
    • 0026611442 scopus 로고
    • Involvement of p21 ras in Xenopus mesoderm induction
    • Whitman M and Melton DA (1992) Involvement of p21 ras in Xenopus mesoderm induction. Nature 357: 252-254
    • (1992) Nature , vol.357 , pp. 252-254
    • Whitman, M.1    Melton, D.A.2
  • 55
    • 0028017632 scopus 로고
    • Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma
    • Yoo GH, Xu HJ, Brennan JA, Westra W, Hruban RH, Koch W, Benedict WF and Sidransky D (1994) Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. Cancer Res 54: 4603-4606
    • (1994) Cancer Res , vol.54 , pp. 4603-4606
    • Yoo, G.H.1    Xu, H.J.2    Brennan, J.A.3    Westra, W.4    Hruban, R.H.5    Koch, W.6    Benedict, W.F.7    Sidransky, D.8
  • 56
    • 0028351556 scopus 로고
    • The pathogenesis of squamous cell cancer: Lessons learned from studies of skin carcinogenesis. Thirty-third GHA clowes memorial award lecture
    • Yuspa SH (1994) The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis. Thirty-third GHA Clowes Memorial Award Lecture. Cancer Res 54: 1178-1189
    • (1994) Cancer Res , vol.54 , pp. 1178-1189
    • Yuspa, S.H.1
  • 57
    • 0021871265 scopus 로고
    • Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurca during initiation of mammary carcinogenesis in rats
    • Zarbl H, Sukumar S, Arthur AV, Martin-Zanca D and Barbacid M (1985) Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurca during initiation of mammary carcinogenesis in rats. Nature 315: 382-385
    • (1985) Nature , vol.315 , pp. 382-385
    • Zarbl, H.1    Sukumar, S.2    Arthur, A.V.3    Martin-Zanca, D.4    Barbacid, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.