-
2
-
-
3543107075
-
Pharmacokinetics in pregnancy and placental drug transfer
-
E. Reynolds and C. Knott: Pharmacokinetics in pregnancy and placental drug transfer. Oxford Rev. Reprod. Biol. 11, 390-429 (1959).
-
(1959)
Oxford Rev. Reprod. Biol.
, vol.11
, pp. 390-429
-
-
Reynolds, E.1
Knott, C.2
-
4
-
-
0014497592
-
Simultaneous measurements of hepatic and portal venous blood flow in sheep and dog
-
M. L. Katz and E. N. Bergman: Simultaneous measurements of hepatic and portal venous blood flow in sheep and dog. Am. J. Physiol. 216, 946-952 (1969).
-
(1969)
Am. J. Physiol.
, vol.216
, pp. 946-952
-
-
Katz, M.L.1
Bergman, E.N.2
-
5
-
-
0018100292
-
Liver and ductus venosus blood flows in fetal lambs in utero
-
D. I. Edelstone, A. M. Rudolph, and M. A. Heymann: Liver and ductus venosus blood flows in fetal lambs in utero. Circ. Res. 42, 426-433 (1978).
-
(1978)
Circ. Res.
, vol.42
, pp. 426-433
-
-
Edelstone, D.I.1
Rudolph, A.M.2
Heymann, M.A.3
-
6
-
-
0019820188
-
A preparation for studying blood flow, oxygen consumption, and metabolism in the fetal lamb in utero
-
J. Bristow, A. M. Rudolph, and J. Itskovitz: A preparation for studying blood flow, oxygen consumption, and metabolism in the fetal lamb in utero. J. Dev. Physiol. 3, 255-266 (1981).
-
(1981)
J. Dev. Physiol.
, vol.3
, pp. 255-266
-
-
Bristow, J.1
Rudolph, A.M.2
Itskovitz, J.3
-
7
-
-
0021467170
-
Fetal and neonatal hepatic perfusion and oxygenation
-
I. R. Holzman: Fetal and neonatal hepatic perfusion and oxygenation. Semin. Perinatal. 8, 234-244 (1984).
-
(1984)
Semin. Perinatal.
, vol.8
, pp. 234-244
-
-
Holzman, I.R.1
-
8
-
-
0018632141
-
Preferential streaming of ductus venosus blood to the brain and heart in fetal lambs
-
D. I. Edelstone and A. M. Rudolph: Preferential streaming of ductus venosus blood to the brain and heart in fetal lambs. Am. J. Physiol. 237, H724-H728 (1979).
-
(1979)
Am. J. Physiol.
, vol.237
-
-
Edelstone, D.I.1
Rudolph, A.M.2
-
9
-
-
0022381509
-
Distribution and regulation of blood flow in the fetal and neonatal lamb
-
A. M. Rudolph: Distribution and regulation of blood flow in the fetal and neonatal lamb. Circ. Res. 57, 811-821 (1985).
-
(1985)
Circ. Res.
, vol.57
, pp. 811-821
-
-
Rudolph, A.M.1
-
10
-
-
0021191326
-
Nutrient and waste product concentration differences in upper and lower body arteries of fetal sheep
-
V. Charlton and M. Johengen: Nutrient and waste product concentration differences in upper and lower body arteries of fetal sheep. J. Dev. Physiol. 6, 431-437 (1984).
-
(1984)
J. Dev. Physiol.
, vol.6
, pp. 431-437
-
-
Charlton, V.1
Johengen, M.2
-
11
-
-
0022271059
-
Animal models for study of fetal drug exposure
-
"Prenatal Drug Exposure: Kinetics and Dynamics" (C. N. Chiang and C. C. Lee, ed.), U.S. Department of Health and Human Services, Rockville, MD
-
A. M Rudolph: Animal models for study of fetal drug exposure. In "Prenatal Drug Exposure: Kinetics and Dynamics" (C. N. Chiang and C. C. Lee, ed.), pp. 5-16, NIDA Research Monograph 60. U.S. Department of Health and Human Services, Rockville, MD, 1985.
-
(1985)
NIDA Research Monograph
, vol.60
, pp. 5-16
-
-
Rudolph, A.M.1
-
12
-
-
0022515847
-
Placental transfer of diphenhydramine in chronically instrumented pregnant sheep
-
S. D. Yoo, J. E. Axelson, S. M. Taylor, and D. W. Rurak: Placental transfer of diphenhydramine in chronically instrumented pregnant sheep. J Pharm. Sci. 75, 685-687 (1986).
-
(1986)
J Pharm. Sci.
, vol.75
, pp. 685-687
-
-
Yoo, S.D.1
Axelson, J.E.2
Taylor, S.M.3
Rurak, D.W.4
-
13
-
-
0027174325
-
Transplacental and nonplacental clearances of diphenhydramine in the chronically instrumented pregnant sheep
-
S. D. Yoo, D. W Rurak, S. M. Taylor, and J. E. Axelson: Transplacental and nonplacental clearances of diphenhydramine in the chronically instrumented pregnant sheep. J. Pharm. Sci. 82, 145-149 (1993).
-
(1993)
J. Pharm. Sci.
, vol.82
, pp. 145-149
-
-
Yoo, S.D.1
Rurak, D.W.2
Taylor, S.M.3
Axelson, J.E.4
-
14
-
-
0022543391
-
Hydroxylation and glucuronidation of various xenobiotics by hepatic micro-somes from the fetal lamb, pregnant ewe and human fetus
-
B. H. Dvorchik, G. Woodward, D. S. Sitar, and W. A. Tweed: Hydroxylation and glucuronidation of various xenobiotics by hepatic micro-somes from the fetal lamb, pregnant ewe and human fetus. Dev. Pharmacol. Ther. 9, 282-289 (1986).
-
(1986)
Dev. Pharmacol. Ther.
, vol.9
, pp. 282-289
-
-
Dvorchik, B.H.1
Woodward, G.2
Sitar, D.S.3
Tweed, W.A.4
-
15
-
-
0022521615
-
Pharmacokinetic studies of the disposition of acetaminophen in sheep maternal-fetal unit
-
L. H. Wang, A. M. Rudolph, and L. Z. Benet: Pharmacokinetic studies of the disposition of acetaminophen in sheep maternal-fetal unit. J. Pharmacol. Exp. Ther. 238, 198-205 (1986).
-
(1986)
J. Pharmacol. Exp. Ther.
, vol.238
, pp. 198-205
-
-
Wang, L.H.1
Rudolph, A.M.2
Benet, L.Z.3
-
16
-
-
0022494396
-
Developmental alterations in hepatic UDP-glucuronyltransferase: A comparison of the kinetic properties of enzymes from adult sheep and fetal lambs
-
L. H. Wang, D. Zakim, A. M. Rudolph, and L. Z. Benet: Developmental alterations in hepatic UDP-glucuronyltransferase: a comparison of the kinetic properties of enzymes from adult sheep and fetal lambs. Biochem. Pharmacol. 35, 3065-3070 (1986).
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 3065-3070
-
-
Wang, L.H.1
Zakim, D.2
Rudolph, A.M.3
Benet, L.Z.4
-
17
-
-
0026042047
-
Clearance and disposition of ritodrine in the fluid compartments of the fetal lamb during and after constant rate fetal intravenous infusion
-
M. R. Wright, D. W. Rurak, M. P. van der Weyde, S. M. Taylor, and J. E. Axelson: Clearance and disposition of ritodrine in the fluid compartments of the fetal lamb during and after constant rate fetal intravenous infusion. J. Pharmacol. Exp. Ther. 258, 897-902 (1991).
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.258
, pp. 897-902
-
-
Wright, M.R.1
Rurak, D.W.2
Van der Weyde, M.P.3
Taylor, S.M.4
Axelson, J.E.5
-
18
-
-
0027424343
-
Transplacental and nonplacental clearances, metabolism and pharmacodynamics of labetalol in the fetal lamb after direct intravenous administration
-
K. Yeleswaram, D. W. Rurak, E. Kwan, C. Hall, A. Doroudian, M. R. Wright, F. S. Abbott, and J. E. Axelson: Transplacental and nonplacental clearances, metabolism and pharmacodynamics of labetalol in the fetal lamb after direct intravenous administration. J. Pharmacol. Exp. Ther. 267, 425-431 (1993).
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 425-431
-
-
Yeleswaram, K.1
Rurak, D.W.2
Kwan, E.3
Hall, C.4
Doroudian, A.5
Wright, M.R.6
Abbott, F.S.7
Axelson, J.E.8
-
19
-
-
0023724793
-
Effects of diphenhydramine in the fetal lamb after maternal or fetal administration
-
D. W. Rurak, S. D. Yoo, E. Kwan, S. M. Taylor, K. W. Riggs, and J. E. Axelson: Effects of diphenhydramine in the fetal lamb after maternal or fetal administration. J. Pharmacol Exp. Ther. 247, 271-278 (1988).
-
(1988)
J. Pharmacol Exp. Ther.
, vol.247
, pp. 271-278
-
-
Rurak, D.W.1
Yoo, S.D.2
Kwan, E.3
Taylor, S.M.4
Riggs, K.W.5
Axelson, J.E.6
-
21
-
-
0027703593
-
10) diphenhydramine using capillary gas chromatography with mass selective detection in biological fluids from chronically instrumented pregnant ewes
-
10) diphenhydramine using capillary gas chromatography with mass selective detection in biological fluids from chronically instrumented pregnant ewes. Biol. Mass Spectrom. 22, 633-642 (1993).
-
(1993)
Biol. Mass Spectrom.
, vol.22
, pp. 633-642
-
-
Tonn, G.R.1
Multib, A.2
Abbott, F.S.3
Rurak, D.W.4
Axelson, J.E.5
-
22
-
-
0004061014
-
-
(J. Swarbrick, ed.). Marcel Dekker. New York
-
M. Gibaldi and D. Perrier: "Pharmacokinetics" (J. Swarbrick, ed.). Marcel Dekker. New York, 1982.
-
(1982)
Pharmacokinetics
-
-
Gibaldi, M.1
Perrier, D.2
-
24
-
-
0027052236
-
Optimum numerical integration methods for estimation of area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC)
-
R. D. Purves: Optimum numerical integration methods for estimation of area-under-the-curve (AUC) and area-under-the-moment-curve (AUMC). J. Pharmacokinet. Biopharmacol. 20, 211-226 (1992).
-
(1992)
J. Pharmacokinet. Biopharmacol.
, vol.20
, pp. 211-226
-
-
Purves, R.D.1
-
25
-
-
0026448685
-
The relevance of residence time theory to pharmacokinetics
-
M. Weiss: The relevance of residence time theory to pharmacokinetics. Eur. J. Clin. Pharmacol. 43, 571-579 (1992).
-
(1992)
Eur. J. Clin. Pharmacol.
, vol.43
, pp. 571-579
-
-
Weiss, M.1
-
26
-
-
0016560388
-
A description of the dynamics of fetal growth in sheep
-
L. J. Koong, W. N. Garrett, and P. V. Rattray: A description of the dynamics of fetal growth in sheep. J. Anim. Sci. 41, 1065-1243 (1975).
-
(1975)
J. Anim. Sci.
, vol.41
, pp. 1065-1243
-
-
Koong, L.J.1
Garrett, W.N.2
Rattray, P.V.3
-
27
-
-
0004252445
-
-
Prentice-Hall, Englewood Cliffs, New Jersey
-
J. H. Zar: "Biostatistical Analysis." Prentice-Hall, Englewood Cliffs, New Jersey, 1984.
-
(1984)
Biostatistical Analysis
-
-
Zar, J.H.1
-
28
-
-
0019435605
-
Fetal hepatic function: The disposition of propranolol in the pregnant sheep
-
A. W. Marshall, G. W. Mihaly, R. A. Smallwood, D. J. Morgan, and K. J. Hardy. Fetal hepatic function: the disposition of propranolol in the pregnant sheep. Res. Commun. Chem. Pathol. Pharmacol. 32, 3-25 (1981).
-
(1981)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.32
, pp. 3-25
-
-
Marshall, A.W.1
Mihaly, G.W.2
Smallwood, R.A.3
Morgan, D.J.4
Hardy, K.J.5
-
29
-
-
0020266010
-
The developing liver: The steady-state disposition of propranolol in pregnant sheep
-
G. W. Mihaly, D. J. Morgan, R. Smallwood, and K. J. Hardy: The developing liver: the steady-state disposition of propranolol in pregnant sheep. Hepatology 2, 344-349 (1982).
-
(1982)
Hepatology
, vol.2
, pp. 344-349
-
-
Mihaly, G.W.1
Morgan, D.J.2
Smallwood, R.3
Hardy, K.J.4
-
30
-
-
0022639059
-
The application of stable isotopes to studies of drug bio-availability and bioequivalence
-
R. L. Wolen: The application of stable isotopes to studies of drug bio-availability and bioequivalence. J. Clin. Pharmacol. 26, 419-424 (1986).
-
(1986)
J. Clin. Pharmacol.
, vol.26
, pp. 419-424
-
-
Wolen, R.L.1
-
31
-
-
0025367713
-
Stable isotopes in clinical pharmacokinetic investigations - Advantages and disadvantages
-
T. R. Browne: Stable isotopes in clinical pharmacokinetic investigations - advantages and disadvantages. Clin. Pharmacokinet. 18, 423-433 (1990).
-
(1990)
Clin. Pharmacokinet.
, vol.18
, pp. 423-433
-
-
Browne, T.R.1
-
32
-
-
0022640655
-
Isotope effects: Definitions and consequences for pharmacologic studies
-
A. Van Langenhove: Isotope effects: definitions and consequences for pharmacologic studies. J. Clin. Pharmacol. 26, 383-389 (1986).
-
(1986)
J. Clin. Pharmacol.
, vol.26
, pp. 383-389
-
-
Van Langenhove, A.1
-
33
-
-
0022627491
-
Drug metabolite identification: Stable isotope methods
-
W. J. A VandenHeuvel: Drug metabolite identification: stable isotope methods. J. Clin. Pharmacol. 26, 427-434 (1986).
-
(1986)
J. Clin. Pharmacol.
, vol.26
, pp. 427-434
-
-
Vandenheuvel, W.J.A.1
-
34
-
-
84865668446
-
Presystemic drug metabolism in the liver
-
"Presystemic Drug Elimination" (C. F. George, D. G. Shand, and A. G. Renwick, eds.), Butterworth Scientific, London
-
C. F. George and D. G. Shand: Presystemic drug metabolism in the liver. In "Presystemic Drug Elimination" (C. F. George, D. G. Shand, and A. G. Renwick, eds.), pp. 69-77. Butterworths International Medical Reviews, Clinical Pharmacology and Therapeutics, vol. 1. Butterworth Scientific, London, 1982.
-
(1982)
Butterworths International Medical Reviews, Clinical Pharmacology and Therapeutics
, vol.1
, pp. 69-77
-
-
George, C.F.1
Shand, D.G.2
-
35
-
-
0025343862
-
Pharmacokinetics of diphenhydramine after dose ranging in nonpregnant ewes
-
S. D. Yoo, J. E. Axelson, E. Kwan, and D. W. Rurak: Pharmacokinetics of diphenhydramine after dose ranging in nonpregnant ewes. J. Pharm. Sci. 79, 106-110 (1990).
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 106-110
-
-
Yoo, S.D.1
Axelson, J.E.2
Kwan, E.3
Rurak, D.W.4
-
36
-
-
0021240623
-
Diphenhydramine disposition in chronic liver disease
-
C. G. Meredith, C. D. Christian, R. F. Johnson, S. V. Madhavan. and S. Schenker: Diphenhydramine disposition in chronic liver disease. Clin. Pharmacol. Ther. 35, 474-479 (1984).
-
(1984)
Clin. Pharmacol. Ther.
, vol.35
, pp. 474-479
-
-
Meredith, C.G.1
Christian, C.D.2
Johnson, R.F.3
Madhavan, S.V.4
Schenker, S.5
-
37
-
-
0018960329
-
Diphenhydramine in orientals and caucasians
-
R. Spector, A. K. Choudhury, C. Chao-Kuo, M. J. Goldberg, and M. M. Ghoneim: Diphenhydramine in orientals and caucasians. Clin. Pharmacol. Ther. 28, 229-234 (1980).
-
(1980)
Clin. Pharmacol. Ther.
, vol.28
, pp. 229-234
-
-
Spector, R.1
Choudhury, A.K.2
Chao-Kuo, C.3
Goldberg, M.J.4
Ghoneim, M.M.5
-
38
-
-
0016792079
-
Pharmacokinetics of diphenhydramine in man
-
K. S. Albert, M. R. Hallmark, E. Sakmur, D. J. Weidler, and S. C. Wagner: Pharmacokinetics of diphenhydramine in man. J. Pharmacokinet. Biopharmacol. 3, 159-170 (1975).
-
(1975)
J. Pharmacokinet. Biopharmacol.
, vol.3
, pp. 159-170
-
-
Albert, K.S.1
Hallmark, M.R.2
Sakmur, E.3
Weidler, D.J.4
Wagner, S.C.5
-
39
-
-
0014886931
-
Species differences in the metabolism of diphenhydramine (benadryl) (35157)
-
J. C. Drach, J. P. Howell, P. E. Borondy, and A. J. Glazko: Species differences in the metabolism of diphenhydramine (benadryl) (35157). Proc. Soc. Exp. Biol. Med. 135, 849-853 (1970).
-
(1970)
Proc. Soc. Exp. Biol. Med.
, vol.135
, pp. 849-853
-
-
Drach, J.C.1
Howell, J.P.2
Borondy, P.E.3
Glazko, A.J.4
-
41
-
-
0016149090
-
Metabolic disposition of diphenhydramine
-
A. J. Glazko, W. A. Dill, R. M. Young, T. C. Smith, and R. I. Ogilvie: Metabolic disposition of diphenhydramine. Clin. Pharmacol. Ther. 16, 1066-1075 (1974).
-
(1974)
Clin. Pharmacol. Ther.
, vol.16
, pp. 1066-1075
-
-
Glazko, A.J.1
Dill, W.A.2
Young, R.M.3
Smith, T.C.4
Ogilvie, R.I.5
-
42
-
-
0028794540
-
The simultaneous analysis of diphenylmethoxyacetic acid, a metabolite of diphenhydramine, and its deuterium labeled stable isotope analog in ovine plasma and urine
-
G. R. Tonn, F. S. Abbott, D. W. Rurak, and J. E. Axelson: The simultaneous analysis of diphenylmethoxyacetic acid, a metabolite of diphenhydramine, and its deuterium labeled stable isotope analog in ovine plasma and urine. J. Chromatogr. 663, 67-81 (1995).
-
(1995)
J. Chromatogr.
, vol.663
, pp. 67-81
-
-
Tonn, G.R.1
Abbott, F.S.2
Rurak, D.W.3
Axelson, J.E.4
-
43
-
-
9044250853
-
Contribution of diphenylmethoxyacetic acid formation to clearance in adult sheep: Application of stable-isotope labeled metabolite
-
abstr.
-
S. Kumar, D. W. Rurak, E. Kwan, and J. E. Axelson: Contribution of diphenylmethoxyacetic acid formation to clearance in adult sheep: application of stable-isotope labeled metabolite. American Academy of Pharmaceutical Science. Annual Meeting, 1995 (abstr.).
-
(1995)
American Academy of Pharmaceutical Science. Annual Meeting
-
-
Kumar, S.1
Rurak, D.W.2
Kwan, E.3
Axelson, J.E.4
-
44
-
-
0023485806
-
Effects of birth-related events on central blood flow patterns
-
D. F. Teitel, H. S. Iwamoto, and A. M. Rudolph: Effects of birth-related events on central blood flow patterns. Pediatr. Res. 22, 557-566 (1982).
-
(1982)
Pediatr. Res.
, vol.22
, pp. 557-566
-
-
Teitel, D.F.1
Iwamoto, H.S.2
Rudolph, A.M.3
|