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Volumn 19, Issue 3 A, 1999, Pages 1893-1899

Aberrant p16 expression is correlated with hemizygous deletions at the 9p21-22 chromosome region in non-small cell lung carcinomas

Author keywords

CDNK2; Chromosome locus 9p21 22; Lung cancer; MTS1 p16(INK4A); p16

Indexed keywords

CYCLIN DEPENDENT KINASE; PROTEIN P16; RETINOBLASTOMA PROTEIN;

EID: 0032791953     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (31)
  • 1
    • 0032547380 scopus 로고    scopus 로고
    • Progress in understanding the molecular pathogenesis of human lung cancer
    • Yoshitaka S, Kwun MF, Minna JD: Progress in understanding the molecular pathogenesis of human lung cancer. Bioch Biophys Acta 1378: F21-F59, 1998.
    • (1998) Bioch Biophys Acta , vol.1378
    • Yoshitaka, S.1    Kwun, M.F.2    Minna, J.D.3
  • 2
  • 4
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371: 257-261, 1994.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 6
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T, Miura K, Wu DJ, Lois A, Takabayashi K, Carson DA: Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature 368: 753-756, 1994.
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 7
    • 0031710479 scopus 로고    scopus 로고
    • The INK4a/ARF tumor suppressor some gene-two products-two pathways
    • Chin L, Pomerantz J, DePinho RA: The INK4a/ARF tumor suppressor some gene-two products-two pathways. TIBS 23: 291-296, 1998.
    • (1998) TIBS , vol.23 , pp. 291-296
    • Chin, L.1    Pomerantz, J.2    DePinho, R.A.3
  • 9
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • Hannon GJ, Beach D: p15INK4B is a potential effector of TGF-β-induced cell cycle arrest. Nature 371: 257-261, 1994.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 10
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, Beach D: A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature 366: 704-707, 1993.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 12
    • 0027960437 scopus 로고
    • Overexpression of human cyclin D1 reduces the transforming growth factor β (TGF-β) type II receptor and growth inhibition by TGF-β1 in an immortalized human esophageal epithelial cell line
    • Okamoto A, Jiang W, Kim S-J, Spillare EA, Stoner GD, Weinstein IB, Harris CC: Overexpression of human cyclin D1 reduces the transforming growth factor β (TGF-β) type II receptor and growth inhibition by TGF-β1 in an immortalized human esophageal epithelial cell line. Proc Natl Acad Sci USA 91: 11576-11580, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11576-11580
    • Okamoto, A.1    Jiang, W.2    Kim, S.-J.3    Spillare, E.A.4    Stoner, G.D.5    Weinstein, I.B.6    Harris, C.C.7
  • 13
    • 0028034775 scopus 로고
    • Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb
    • Li Y, Nichols MA, Shay JW, Xiong Y: Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb. Cancer Res 54: 6078-6082, 1994.
    • (1994) Cancer Res , vol.54 , pp. 6078-6082
    • Li, Y.1    Nichols, M.A.2    Shay, J.W.3    Xiong, Y.4
  • 17
    • 0028085975 scopus 로고
    • Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
    • Kamb A, Shattuck-Eidens D, Eeles R et al: Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat Genet 8: 22-26, 1994.
    • (1994) Nat Genet , vol.8 , pp. 22-26
    • Kamb, A.1    Shattuck-Eidens, D.2    Eeles, R.3
  • 19
    • 0028338514 scopus 로고
    • Frequent somatic mutation of the MTS1/CDK41 (multiple tumor suppressor/cyclin-.,dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma
    • Mori T, Miura K, Aoki T, Nishihira T, Mori S, Nakamura Y: Frequent somatic mutation of the MTS1/CDK41 (multiple tumor suppressor/cyclin-.,dependent kinase 4 inhibitor) gene in esophageal squamous cell carcinoma. Cancer Res 54: 3396-3397, 1994.
    • (1994) Cancer Res , vol.54 , pp. 3396-3397
    • Mori, T.1    Miura, K.2    Aoki, T.3    Nishihira, T.4    Mori, S.5    Nakamura, Y.6
  • 20
    • 0028875205 scopus 로고
    • Methylation of the 5 'CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS, Nguyen T, Beart RW, Van Tornour JM, Jones PA: Methylation of the 5 'CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res 55: 4531-4535, 1995.
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.4    Beart, R.W.5    Van Tornour, J.M.6    Jones, P.A.7
  • 21
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa J-PJ, Davidson NE, Sidransky D, Baylin SB: Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55: 4525-4530, 1995.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.-P.J.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 22
    • 0028787221 scopus 로고
    • CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5- Aza 2′ deoxycytidine
    • Otterson GA, Khleif SN, Chen W, Coxon AB, Kaye FJ: CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5- aza 2′ deoxycytidine. Oncogene 11: 1211-1216, 1995.
    • (1995) Oncogene , vol.11 , pp. 1211-1216
    • Otterson, G.A.1    Khleif, S.N.2    Chen, W.3    Coxon, A.B.4    Kaye, F.J.5
  • 23
    • 0032576630 scopus 로고    scopus 로고
    • Mechanisms of p16INK4A inactivation in non small-cell lung cancers
    • Gazzeri S, Gouyer V, Vourtch C, Brambilla C, Brambilla E. Mechanisms of p16INK4A inactivation in non small-cell lung cancers. Oncogene 16: 497-504, 1998.
    • (1998) Oncogene , vol.16 , pp. 497-504
    • Gazzeri, S.1    Gouyer, V.2    Vourtch, C.3    Brambilla, C.4    Brambilla, E.5
  • 25
    • 0020070666 scopus 로고
    • The World Health Organization histologic typing of lung tumours
    • World Health Organization. The World Health Organization histologic typing of lung tumours. Am J Clin Pathol 77: 123-136, 1982.
    • (1982) Am J Clin Pathol , vol.77 , pp. 123-136
  • 27
    • 0029901708 scopus 로고    scopus 로고
    • High frequency of aberrant p16INK4A expression in human breast cancer
    • Geradts J, Wilson PA: High frequency of aberrant p16INK4A expression in human breast cancer. Am J Pathol 149: 15-20, 1996.
    • (1996) Am J Pathol , vol.149 , pp. 15-20
    • Geradts, J.1    Wilson, P.A.2
  • 29
    • 0028909163 scopus 로고
    • Microsatellite instability and other molecular abnormalities in non-small cell lung cancer
    • Fong KM, Zimmermann PV, Smith PJ: Microsatellite instability and other molecular abnormalities in non-small cell lung cancer. Cancer Res 55: 28-30, 1995.
    • (1995) Cancer Res , vol.55 , pp. 28-30
    • Fong, K.M.1    Zimmermann, P.V.2    Smith, P.J.3
  • 30
    • 0031841276 scopus 로고    scopus 로고
    • DNA missmatch repair and colorectal cancer
    • Toft NJ, Arends MJ: DNA missmatch repair and colorectal cancer. J Pathol 185(2): 123-129, 1998.
    • (1998) J Pathol , vol.185 , Issue.2 , pp. 123-129
    • Toft, N.J.1    Arends, M.J.2
  • 31
    • 0028813895 scopus 로고
    • Microsatellite instability in inherited and sporadic neoplasms
    • Eshelman JR, Marcowitz SD: Microsatellite instability in inherited and sporadic neoplasms. Curr Opin Oncol 7: 83-89, 1995.
    • (1995) Curr Opin Oncol , vol.7 , pp. 83-89
    • Eshelman, J.R.1    Marcowitz, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.