Investigation of the major human hepatic cytochrome P450 involved in 4- hydroxylation and N-dechloroethylation of trofosfamide

Cancer Chemotherapy and Pharmacology

Volumn 44, Issue 4, 1999, Pages 327-334

  May Manke, Antje ^a   Kroemer, Heyo ^b   Hempel, Georg ^a   Bohnenstengel, Frank ^c   Hohenlöchter, Barbara ^a   Blaschke, Gottfried ^d   Boos, Joachim ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Cyclophosphamide; Cytochrome P450; Ifosfamide; Metabolism; Trofosfamide

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOCHROME P450; IFOSFAMIDE; KETOCONAZOLE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TROFOSFAMIDE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME KINETICS; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER METABOLISM; LIVER MICROSOME; PRIORITY JOURNAL;

EID: 0032790040     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050985     Document Type: Article

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